SMURF2

General Information

Gene Name       : SMURF2
Gene ID             : ENSG00000108854.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SMURF2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SMURF2ENSG00000108854.158.038.188.11ENCSR000AEF
HepG2SMURF2ENSG00000108854.1515.3417.9716.66ENCSR985KAT
K562SMURF2ENSG00000108854.1511.4711.0511.26ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SMURF2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SMURF2 RNA is bound by 14 proteins.  







eCLIP assay for SMURF2 is not avaliable on ENCORE database.





14 proteins are bound to SMURF2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr176256793262568052-3'-UTR,CDS,intron-Distal3.922563.31827HepG2GRWD1
chr176255193562552019-3'-UTR,CDS,intron-Distal,intron-Proximal4.012876.22576HepG2BCLAF1
chr176255901362559102-3'-UTR,CDS,intron-Distal,intron-Proximal4.550983.93614HepG2AQR
chr176258219762582286-3'-UTR,CDS,intron-Distal,intron-Proximal3.297643.34848HepG2PPIG
chr176255900662559089-3'-UTR,CDS,intron-Distal,intron-Proximal3.187845.63425HepG2BCLAF1
chr176258720062587259-3'-UTR,CDS,intron-Distal,intron-Proximal3.791074.09885HepG2BCLAF1
chr176256800062568087-3'-UTR,CDS,intron-Distal,intron-Proximal4.466594.45977HepG2U2AF2
chr176257461662574713-3'-UTR,CDS,intron-Distal,intron-Proximal3.401643.75245K562BUD13
chr176254771762547818-3'-UTR,CDS,intron-Distal3.165305.40132HepG2BCLAF1
chr176254189962541988-3'-UTR,CDS,intron-Distal4.242596.22576HepG2BCLAF1
chr176257691462577017-3'-UTR,CDS,intron-Distal3.255783.69481K562UCHL5
chr176265785562657923-intron-Distal3.904264.33898HepG2FAM120A
chr176260982962609894-intron-Distal4.537879.98238HepG2HNRNPL
chr176265520262655321-intron-Distal4.1394012.70351HepG2HNRNPL
chr176265238062652472-intron-Distal3.720303.02234K562KHSRP
chr176265768562657744-intron-Distal3.424094.14880HepG2CSTF2T
chr176265778462657917-intron-Distal4.741256.54349K562CSTF2T
chr176260976662609817-intron-Distal4.019933.98095HepG2HNRNPL
chr176259545762595570-intron-Distal5.290585.17615K562AQR
chr176260479462604883-intron-Distal5.053577.06230K562EXOSC5
chr176260973162609819-intron-Distal4.149905.74048K562AGGF1
chr176257639862576500-intron-Distal3.468854.76345K562KHSRP
chr176260492562605064-intron-Distal5.215299.35180K562EXOSC5
chr176262730462627372-intron-Distal4.200186.43614HepG2PCBP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SMURF2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SMURF2 is not available on ENCORE database.

  • 57 RBPs can affect the levels of SMURF2.  








The Knockdown/knockout RNA-Seq assay for SMURF2 is not available on ENCORE database.





57 RBPs can affect the gene expression of SMURF2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SMURF2ENSG00000108854.11833.44060601.828600.469603.730702.49590HepG2AATF
SMURF2ENSG00000108854.111750.02530795.869301.1367043.4535041.75960HepG2ACO1
SMURF2ENSG00000108854.11518.05870678.08660-0.388402.397201.46650HepG2ADAR
SMURF2ENSG00000108854.111388.688001096.482400.340701.928101.47480HepG2AKAP1
SMURF2ENSG00000108854.111481.919901151.963400.363303.363402.61900HepG2AUH
SMURF2ENSG00000108854.111277.85330884.816400.530206.294605.19230HepG2CALR
SMURF2ENSG00000108854.111373.182101067.643800.363002.138701.52480HepG2CPSF6
SMURF2ENSG00000108854.111546.71630971.515800.6708013.1105011.91450HepG2CELF1
SMURF2ENSG00000108854.11850.38570649.775600.388103.074102.11050HepG2DDX24
SMURF2ENSG00000108854.11676.813701050.33830-0.634005.662904.79760HepG2DDX3X
SMURF2ENSG00000108854.111515.65260605.884001.3227020.5885018.77190HepG2DDX55
SMURF2ENSG00000108854.111949.707201212.374700.685304.065502.89300HepG2DDX59
SMURF2ENSG00000108854.11548.16750676.78450-0.304102.688802.04450HepG2DNAJC2
SMURF2ENSG00000108854.111226.823501030.591400.251402.119901.37120HepG2EIF4G1
SMURF2ENSG00000108854.111361.77270987.255000.463904.048003.07660HepG2EIF4G2
SMURF2ENSG00000108854.112738.468501322.597301.0499035.2352033.52900HepG2ETF1
SMURF2ENSG00000108854.112792.524801035.474501.4312029.9707027.95670HepG2FIP1L1
SMURF2ENSG00000108854.11722.89260569.314300.344502.251701.53620HepG2FUBP3
SMURF2ENSG00000108854.11608.169501210.36740-0.992907.363106.34900HepG2GPKOW
SMURF2ENSG00000108854.11797.425401044.73260-0.389702.001201.37830HepG2IGF2BP1
SMURF2ENSG00000108854.11675.60880972.89610-0.526103.712602.99210HepG2MATR3
SMURF2ENSG00000108854.111107.20450838.354600.401203.915402.95740HepG2MSI2
SMURF2ENSG00000108854.11785.91680995.80920-0.341501.918501.38590HepG2NCBP2
SMURF2ENSG00000108854.111163.74300829.643700.488102.263701.47520HepG2PABPC1
SMURF2ENSG00000108854.111053.02210851.893300.305702.238701.73640HepG2PTBP1
SMURF2ENSG00000108854.11918.053701049.68660-0.193301.891801.38140HepG2PUM1
SMURF2ENSG00000108854.111211.87890922.767100.393103.767103.05490HepG2QKI
SMURF2ENSG00000108854.111088.66070774.465600.491202.196701.56260HepG2RAVER1
SMURF2ENSG00000108854.111394.757101105.448900.335303.490402.92710HepG2RBM22
SMURF2ENSG00000108854.111048.86360837.415400.324702.294501.67490HepG2RBM25
SMURF2ENSG00000108854.111602.045101142.647700.487405.498904.58280HepG2RPLP0
SMURF2ENSG00000108854.11638.31450462.429200.464902.750701.96550HepG2RRP9
SMURF2ENSG00000108854.113414.654101248.567801.4514094.1303092.26630HepG2SRFBP1
SMURF2ENSG00000108854.111296.43920925.841700.485604.521103.95340HepG2SRSF1
SMURF2ENSG00000108854.111285.25810976.317300.396504.994904.19360HepG2SRSF5
SMURF2ENSG00000108854.111136.37860753.178500.593309.550308.63220HepG2SRSF9
SMURF2ENSG00000108854.111374.585601084.059400.342504.502003.87960HepG2SSB
SMURF2ENSG00000108854.11960.971501110.37280-0.208501.996201.45150HepG2SUCLG1
SMURF2ENSG00000108854.111165.40490603.170400.9501010.883209.68870HepG2SUPV3L1
SMURF2ENSG00000108854.111109.74420832.043900.415404.005903.35040HepG2TAF15
SMURF2ENSG00000108854.11966.86090764.682200.338302.525501.72420HepG2TIA1
SMURF2ENSG00000108854.11900.89510740.096200.283502.104001.65620HepG2TIAL1
SMURF2ENSG00000108854.11631.86500746.74400-0.241001.826601.34910HepG2TRIM56
SMURF2ENSG00000108854.111304.36400885.957300.557905.441504.57740HepG2U2AF1
SMURF2ENSG00000108854.11970.22550743.003400.384904.633503.80110HepG2ZC3H8
SMURF2ENSG00000108854.11714.61960980.58330-0.456502.603401.42650K562ABCF1
SMURF2ENSG00000108854.11706.18280861.63910-0.287002.304001.77800K562AGGF1
SMURF2ENSG00000108854.11680.91480896.57180-0.396902.977202.29870K562AKAP8L
SMURF2ENSG00000108854.11843.13480600.211500.490204.428803.43660K562CPSF6
SMURF2ENSG00000108854.11236.00830382.65540-0.697203.781702.25340K562EEF2
SMURF2ENSG00000108854.11647.98770480.022500.432802.196901.57750K562G3BP2
SMURF2ENSG00000108854.11429.46840573.04910-0.416102.646601.86790K562GPKOW
SMURF2ENSG00000108854.11516.71570741.55450-0.521204.341403.39890K562GRSF1
SMURF2ENSG00000108854.11442.83780598.56500-0.434703.278902.26550K562MATR3
SMURF2ENSG00000108854.11405.02040615.29020-0.603306.684205.47680K562MTPAP
SMURF2ENSG00000108854.11511.63170683.68970-0.418203.423002.60210K562NSUN2
SMURF2ENSG00000108854.11547.24430799.99520-0.547803.325302.41160K562PPIG
SMURF2ENSG00000108854.11435.00360558.81030-0.361302.139701.40470K562RBM22
SMURF2ENSG00000108854.11446.76890588.04080-0.396402.386901.38710K562NELFE
SMURF2ENSG00000108854.11438.77150578.14500-0.398002.361801.70620K562TARDBP
SMURF2ENSG00000108854.11722.04300465.333500.633704.854703.32080K562U2AF1
SMURF2ENSG00000108854.11801.75210480.576500.738309.735608.22750K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SMURF2 is not available on ENCORE database.





5 RBPs can affect the splicing of SMURF2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESMURF2ENSG00000108854.11chr17-6259010862590222625895576258969162594499625946080.173000.000240.04910includedK562MTPAP
SESMURF2ENSG00000108854.11chr17-6259010862590222625895576258969162594499625946080.095000.000540.04310includedK562HNRNPUL1
SESMURF2ENSG00000108854.11chr17-6259010862590222625895576258969162594499625946080.199000.002660.05813includedK562AGGF1
SESMURF2ENSG00000108854.11chr17-6259010862590222625895576258969162594499625946080.121000.000070.02207includedK562NPM1
A3SSSMURF2ENSG00000108854.11chr17-6258220362582325625822036258228862587201625872620.100000.009820.05209longerK562AQR
A3SSSMURF2ENSG00000108854.11chr17-6257460962574712625746096257469462576906625771090.158000.000720.00517longerK562AQR
A3SSSMURF2ENSG00000108854.11chr17-6258720162587327625872016258726762589557625896910.114000.000190.00157longerK562AQR
A3SSSMURF2ENSG00000108854.11chr17-6255097362551192625509736255111162551937625521160.083000.000010.00015longerK562AQR
A3SSSMURF2ENSG00000108854.11chr17-6254371762543946625437176254391962547701625478220.092000.001150.00785longerK562AQR
A3SSSMURF2ENSG00000108854.11chr17-6254238062542486625423806254245662543717625439190.106000.004990.02882longerK562AQR
MXESMURF2ENSG00000108854.11chr17-62547701625478226255097362551149625437176254391962551937625521160.073000.016970.096521includedK562AQR
MXESMURF2ENSG00000108854.11chr17-62547701625479236255097362551149625437176254391962551937625521160.074000.016210.093161includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SMURF2 is not avaliable on ENCORE database.