SECISBP2

General Information

Gene Name : SECISBP2
Gene ID : ENSG00000187742.14
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: SECISBP2)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SECISBP2	ENSG00000187742.14	42.34	32.88	37.61	ENCSR000AEF
HepG2	SECISBP2	ENSG00000187742.14	18.86	26.31	22.59	ENCSR985KAT
K562	SECISBP2	ENSG00000187742.14	22.22	24.20	23.21	ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	BGKcLV33-37,BGKcLV33-38		SECISBP2	K562	Released			CRISPR	KD% = no band on the position,

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

GeneName	Cell_Line	Method	Sample_reps	Control_reps	KD%	Status	Project
SECISBP2	K562	CRISPR	BGKcLV33-37,BGKcLV33-38	BGKcLV33-1,BGKcLV33-2	no band on the position,	Released	ENCODE4
SECISBP2	K562	CRISPR	BGKcLV33-43,BGKcLV33-44	BGKcLV33-1,BGKcLV33-2	0.0,0.0	NotSatisfied	ENCODE4
SECISBP2	K562	CRISPR	BGKcLV35-65,BGKcLV35-66	BGKcLV35-1,BGKcLV35-2	8.0,0.0	NotSatisfied	ENCORE2
SECISBP2	HepG2	CRISPR	BGHcLV31-39,BGHcLV31-40	BGHcLV31-1,BGHcLV31-2	NO CLEAR BAND,	NotSatisfied	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SECISBP2 is not avaliable on ENCORE database.

Proteins bound to RNA

SECISBP2 RNA is bound by 19 proteins.

CanvasJS.com

eCLIP assay for SECISBP2 is not avaliable on ENCORE database.

19 proteins are bound to SECISBP2 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr9	91934758	91934872	+	intron-Distal,intron-Proximal	8.12321	47.51028	HepG2	XPO5
chr9	91963047	91963115	+	CDS	6.24835	17.22331	HepG2	BCLAF1
chr9	91972382	91972482	+	CDS,intron-Proximal	4.80692	15.55279	HepG2	BCLAF1
chr9	91935618	91935706	+	intron-Distal	4.26570	15.49278	HepG2	U2AF2
chr9	91940841	91940898	+	CDS	5.18262	14.25738	HepG2	BCLAF1
chr9	91935880	91935987	+	intron-Distal	4.72724	13.69723	K562	KHSRP
chr9	91965595	91965766	+	CDS	3.46514	13.63814	HepG2	BCLAF1
chr9	91935798	91935846	+	intron-Distal	4.03840	13.08623	K562	KHSRP
chr9	91935846	91935880	+	intron-Distal	3.61634	11.04913	K562	KHSRP
chr9	91947384	91947454	+	intron-Distal	4.51747	8.98750	HepG2	U2AF2
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 95 entries

eCLIP assay for SECISBP2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for SECISBP2 is not available on ENCORE database.
60 RBPs can affect the levels of SECISBP2.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for SECISBP2 is not available on ENCORE database.

60 RBPs can affect the gene expression of SECISBP2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SECISBP2	ENSG00000187742.10	2788.10830	1735.70320	0.68370	21.96640	20.90570	HepG2	SRFBP1
SECISBP2	ENSG00000187742.10	718.70570	1450.77420	-1.01340	14.28600	12.97660	HepG2	DDX3X
SECISBP2	ENSG00000187742.10	626.26060	1246.20870	-0.99270	11.74740	10.58140	HepG2	DDX6
SECISBP2	ENSG00000187742.10	2065.42010	1349.73200	0.61370	11.39150	10.25180	HepG2	QKI
SECISBP2	ENSG00000187742.10	1535.71240	897.08280	0.77550	10.38430	9.13640	HepG2	CPSF6
SECISBP2	ENSG00000187742.10	1010.31040	1461.22970	-0.53240	9.86710	8.61620	K562	UPF1
SECISBP2	ENSG00000187742.10	655.88550	1009.48230	-0.62210	9.08680	8.06410	K562	FXR1
SECISBP2	ENSG00000187742.10	587.81170	948.79330	-0.69070	8.17470	7.19870	K562	HNRNPC
SECISBP2	ENSG00000187742.10	679.34310	1060.31760	-0.64230	7.93180	6.74140	K562	SRSF1
SECISBP2	ENSG00000187742.10	1504.75120	2288.72350	-0.60500	8.08240	6.68350	K562	PUF60
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 66 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SECISBP2 is not available on ENCORE database.

12 RBPs can affect the splicing of SECISBP2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
A3SS	SECISBP2	ENSG00000187742.10	chr9	+	91953344	91953495			91953372	91953495	91949404	91949645	0.16800	0.00000	0.00000	longer	K562	AQR
MXE	SECISBP2	ENSG00000187742.10	chr9	+	91934566	91934712	91940341	91940591	91933420	91933527	91940811	91940953	0.32200	0.00000	0.00001	1included	HepG2	MATR3
MXE	SECISBP2	ENSG00000187742.10	chr9	+	91934566	91934712	91940341	91940591	91933420	91933527	91940811	91940953	-0.29700	0.00000	0.00001	2included	K562	AQR
SE	SECISBP2	ENSG00000187742.10	chr9	+	91954778	91954868			91953372	91953495	91956261	91956394	-0.13100	0.00002	0.00224	excluded	HepG2	SF3B4
A3SS	SECISBP2	ENSG00000187742.10	chr9	+	91940341	91940591			91940462	91940591	91934566	91934712	-0.48900	0.00007	0.00895	shorter	HepG2	SRSF1
A3SS	SECISBP2	ENSG00000187742.10	chr9	+	91940341	91940591			91940462	91940591	91934566	91934712	-0.38200	0.00008	0.00893	shorter	HepG2	SF3B4
A3SS	SECISBP2	ENSG00000187742.10	chr9	+	91940341	91940591			91940462	91940591	91934566	91934712	-0.38100	0.00011	0.00720	shorter	K562	U2AF1
MXE	SECISBP2	ENSG00000187742.10	chr9	+	91934566	91934712	91940341	91940591	91933420	91933527	91940811	91940953	0.24000	0.00016	0.01258	1included	HepG2	DDX3X
MXE	SECISBP2	ENSG00000187742.10	chr9	+	91934566	91934712	91940341	91940591	91933420	91933527	91940811	91940953	0.21500	0.00017	0.01667	1included	HepG2	IGF2BP3
A3SS	SECISBP2	ENSG00000187742.10	chr9	+	91949436	91949645			91949550	91949645	91947822	91947901	0.35300	0.00026	0.00861	longer	HepG2	U2AF2

Showing 1 to 10 of 21 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SECISBP2

General Information

Functions

Localization

Domains (AlphaFold: SECISBP2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SECISBP2 is not avaliable on ENCORE database.

19 proteins are bound to SECISBP2 RNA:

eCLIP assay for SECISBP2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SECISBP2 is not available on ENCORE database.

60 RBPs can affect the gene expression of SECISBP2 :

The Knockdown/knockout RNA-Seq assay for SECISBP2 is not available on ENCORE database.

12 RBPs can affect the splicing of SECISBP2 :

The Knockdown/knockout RNA-Seq assay for SECISBP2 is not avaliable on ENCORE database.