PIAS1

General Information

Gene Name       : PIAS1
Gene ID             : ENSG00000033800.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PIAS1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PIAS1ENSG00000033800.1347.0242.5044.76ENCSR000AEF
HepG2PIAS1ENSG00000033800.1319.6423.5221.58ENCSR985KAT
K562PIAS1ENSG00000033800.1335.6039.7437.67ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PIAS1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PIAS1 RNA is bound by 26 proteins.  







eCLIP assay for PIAS1 is not avaliable on ENCORE database.





26 proteins are bound to PIAS1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr156847986168479934+3'-UTR,CDS,intron-Proximal4.299224.88594K562U2AF2
chr156847987868479929+3'-UTR,CDS,intron-Proximal3.028753.90516K562IGF2BP1
chr156843426968434369+3'-UTR,CDS,intron-Proximal4.296206.60968K562BUD13
chr156848147668481560+3'-UTR,intron-Proximal3.855624.92393K562PUM2
chr156843428368434332+3'-UTR,CDS,intron-Proximal4.547224.36101K562U2AF1
chr156843427868434336+3'-UTR,CDS,intron-Proximal3.954853.23382HepG2U2AF1
chr156847985868479933+3'-UTR,CDS,intron-Proximal3.117046.06877HepG2U2AF2
chr156837888068378944+5'-UTR,CDS3.165566.78391K562RBM15
chr156834691668346982+5'-UTR,intron-Distal3.698813.14687K562CSTF2T
chr156837885068379047+5'-UTR,CDS3.000567.10182HepG2GRWD1
chr156837890768379037+5'-UTR,CDS3.780106.50713K562IGF2BP2
chr156846808868468105+CDS3.152333.02345K562ZNF622
chr156847367168473733+CDS,intron-Proximal4.894446.81564HepG2PRPF8
chr156846802168468116+CDS,intron-Proximal3.324265.60389HepG2PPIG
chr156847368968473748+CDS,intron-Proximal4.031117.79506K562AQR
chr156843890668438945+CDS3.088683.26275K562BUD13
chr156845708168457141+CDS3.215075.40132HepG2BCLAF1
chr156847367668473742+CDS,intron-Proximal3.291914.98422K562PRPF8
chr156843893968439038+CDS3.839433.39506K562IGF2BP2
chr156844600968446057+CDS,intron-Proximal4.601964.35676HepG2PRPF8
chr156848193468481990+intron-Distal4.901275.76540K562PUM2
chr156841388368413942+intron-Distal5.322327.45191HepG2PTBP1
chr156839272268392793+intron-Distal3.406003.64762HepG2QKI
chr156847375368473825+intron-Distal,intron-Proximal3.323894.65237HepG2U2AF2
chr156847325668473385+intron-Distal3.131913.31830K562KHSRP
chr156840804768408165+intron-Distal4.593614.31871HepG2HNRNPM
chr156841395568414015+intron-Distal4.536023.96879HepG2MATR3
chr156840051068400632+intron-Distal4.576485.61842HepG2MATR3
chr156840076968400850+intron-Distal4.174048.40396K562MATR3
chr156841232668412371+intron-Distal3.829283.23532K562MATR3
chr156838061268380714+intron-Distal4.599174.53660HepG2KHSRP
chr156845071168450771+intron-Distal4.183804.10336HepG2SUGP2
chr156840824968408326+intron-Distal4.088784.58794K562KHSRP
chr156841854768418598+intron-Distal4.586518.54919HepG2PTBP1
chr156840078768400851+intron-Distal3.669534.59863HepG2PTBP1
chr156838078868380823+intron-Distal3.745613.26999K562KHSRP
chr156841718868417431+intron-Distal3.118508.64789K562KHSRP
chr156840104268401077+intron-Distal3.778876.02877HepG2SUGP2
chr156840841468408485+intron-Distal3.500984.02190K562EXOSC5
chr156840806568408114+intron-Distal3.185053.69184HepG2SUGP2
chr156843970768439786+intron-Distal5.1173916.87092K562KHSRP
chr156840118768401271+intron-Distal4.196247.54890HepG2SUGP2
chr156841388768413955+intron-Distal3.814494.94624HepG2MATR3
chr156838055368380666+intron-Distal3.109107.30615K562KHSRP
chr156840142168401461+intron-Distal3.454634.81844HepG2SUGP2
chr156840078868400847+intron-Distal3.968639.95261K562PTBP1
chr156848197468482075+intron-Distal3.924803.22972K562TARDBP
chr156840135768401542+intron-Distal4.911418.36737HepG2MATR3
chr156844610268446195+intron-Distal,intron-Proximal4.986076.04760K562AQR
chr156840141668401521+intron-Distal5.060808.08294K562MATR3
chr156843397068434037+intron-Distal3.870885.78005K562KHSRP
chr156840054268400634+intron-Distal3.361728.80382HepG2SUGP2
chr156845041468450475+intron-Distal4.239324.51299HepG2SUGP2
chr156840075868400847+intron-Distal3.449543.57598HepG2MATR3
chr156838041468380493+intron-Distal3.884403.95921HepG2U2AF2
chr156835497668355074+intron-Distal4.274186.04113HepG2CSTF2
chr156838033868380412+intron-Distal3.440586.57673K562KHSRP
chr156843365468433758+intron-Distal3.246323.00914HepG2PTBP1
chr156838054968380594+intron-Distal4.002263.73609HepG2KHSRP
chr156843403768434115+intron-Distal3.475417.01633K562KHSRP
chr156843386368433948+intron-Distal4.374795.19823K562KHSRP
chr156847510868475222+intron-Distal3.289834.30679K562KHSRP
chr156847585068475908+intron-Distal,intron-Proximal3.882123.89294K562KHSRP
chr156839180768391934+intron-Distal3.6532012.20105K562KHSRP
chr156841258868412631+intron-Distal4.088734.28663HepG2SUGP2
chr156843411568434162+intron-Distal3.927823.66668K562KHSRP
chr156844978168449830+intron-Distal3.922023.63454HepG2SUGP2
chr156841861168418676+intron-Distal5.549017.45191HepG2PTBP1
chr156841337368413454+intron-Distal4.077093.89294K562KHSRP
chr156838397168384135+intron-Distal3.039045.27540HepG2HNRNPL
chr156841232668412386+intron-Distal3.318717.80569HepG2SUGP2
chr156838326468383360+intron-Distal4.903735.14653K562EIF4G2
chr156848064068480695+intron-Distal,intron-Proximal3.683645.01178K562PUM2
chr156841853968418673+intron-Distal3.9761213.48919K562PTBP1
chr156841540068415474+intron-Distal4.095574.43741HepG2HNRNPC
chr156841389168413992+intron-Distal4.785556.26399K562MATR3
chr156840464068404795+intron-Distal4.239003.47525K562MATR3
chr156839071768390797+intron-Distal3.827013.20552HepG2KHSRP
chr156841387668413946+intron-Distal4.374827.56720K562PTBP1
chr156841855468418672+intron-Distal4.1656912.25105HepG2QKI
chr156841859868418611+intron-Distal5.147355.07733HepG2PTBP1
chr156840051568400606+intron-Distal4.794515.51760K562MATR3
chr156841749468417567+intron-Distal3.950825.16181K562PTBP1
chr156838327468383363+intron-Distal4.606095.97091K562TARDBP
chr156840463468404739+intron-Distal3.775524.19039HepG2PTBP1
chr156843374068433805+intron-Distal4.464705.85485K562KHSRP
chr156838399968384069+intron-Distal3.903143.14791K562HNRNPL
chr156837910668379188+intron-Proximal4.958626.45599K562PRPF8
chr156848057368480650+intron-Proximal3.917293.47043HepG2KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PIAS1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PIAS1 is not available on ENCORE database.

  • 51 RBPs can affect the levels of PIAS1.  








The Knockdown/knockout RNA-Seq assay for PIAS1 is not available on ENCORE database.





51 RBPs can affect the gene expression of PIAS1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PIAS1ENSG00000033800.9752.83990567.058600.408702.148101.67320HepG2AKAP1
PIAS1ENSG00000033800.9300.65560460.82140-0.616103.022402.03910HepG2BCCIP
PIAS1ENSG00000033800.9720.592301306.66370-0.858605.311404.51590HepG2BOP1
PIAS1ENSG00000033800.9808.376401090.26690-0.431604.212303.28470HepG2CALR
PIAS1ENSG00000033800.9519.88570653.17270-0.329302.483901.86840HepG2CELF1
PIAS1ENSG00000033800.9549.49140702.34120-0.354103.498802.68230HepG2DAZAP1
PIAS1ENSG00000033800.9421.97270553.67770-0.391902.372001.73790HepG2DDX21
PIAS1ENSG00000033800.9503.32140646.77010-0.361802.822402.11480HepG2DNAJC21
PIAS1ENSG00000033800.9494.24020641.08670-0.375303.674002.94210HepG2DNAJC2
PIAS1ENSG00000033800.9431.37720663.74290-0.621705.272604.16740HepG2EIF4G2
PIAS1ENSG00000033800.9395.47930527.59150-0.415802.697301.56590HepG2FASTKD2
PIAS1ENSG00000033800.9887.028501360.01670-0.616602.834202.18620HepG2GPKOW
PIAS1ENSG00000033800.9492.98170726.31390-0.559104.561403.68570HepG2HNRNPC
PIAS1ENSG00000033800.9552.74460721.51130-0.384403.678602.98930HepG2HNRNPU
PIAS1ENSG00000033800.9377.72600507.80590-0.426902.468501.40120HepG2LARP7
PIAS1ENSG00000033800.9362.04750533.23570-0.558603.810002.38550HepG2LIN28B
PIAS1ENSG00000033800.9409.97690664.80640-0.697403.127202.49970HepG2PUF60
PIAS1ENSG00000033800.9778.006201016.42510-0.385703.146602.42550HepG2RPLP0
PIAS1ENSG00000033800.9506.68770642.53220-0.342702.912302.25560HepG2SAFB2
PIAS1ENSG00000033800.9447.57440545.43210-0.285301.831501.33370HepG2SF3B4
PIAS1ENSG00000033800.9902.622501429.44750-0.663302.818302.03010HepG2SNRNP70
PIAS1ENSG00000033800.91032.90090877.900100.234502.276401.80770HepG2SRFBP1
PIAS1ENSG00000033800.9740.35970569.304700.378903.193202.69470HepG2SRSF1
PIAS1ENSG00000033800.9732.20130926.98890-0.340303.543102.76930HepG2SRSF7
PIAS1ENSG00000033800.9625.565601264.67240-1.015506.628405.57150HepG2TARDBP
PIAS1ENSG00000033800.9487.34920707.35240-0.537506.282905.49480HepG2TRIM56
PIAS1ENSG00000033800.91363.791001049.591900.377702.822602.18820HepG2U2AF1
PIAS1ENSG00000033800.91541.62160872.034900.821902.314401.42150HepG2U2AF2
PIAS1ENSG00000033800.9704.14690903.62280-0.359803.923503.11400HepG2UPF1
PIAS1ENSG00000033800.9300.01390444.00550-0.565502.817002.08650HepG2XRN2
PIAS1ENSG00000033800.9713.61740993.81710-0.477807.430706.64650HepG2ZNF622
PIAS1ENSG00000033800.91604.639001148.363800.482608.085707.18590K562AGGF1
PIAS1ENSG00000033800.91605.019301194.918100.425603.086602.39570K562AKAP8L
PIAS1ENSG00000033800.91267.93620993.203000.352202.441201.88360K562AQR
PIAS1ENSG00000033800.9879.82190678.362800.375102.636001.61540K562CCAR1
PIAS1ENSG00000033800.91467.258201797.63510-0.293003.610702.33980K562CPEB4
PIAS1ENSG00000033800.91437.457401860.48060-0.372203.916103.15980K562DDX47
PIAS1ENSG00000033800.91326.828801654.71170-0.318603.491002.43840K562EIF4G2
PIAS1ENSG00000033800.9432.34080603.75920-0.481803.015501.52080K562GEMIN5
PIAS1ENSG00000033800.9879.243301206.77670-0.456804.438103.48470K562GRSF1
PIAS1ENSG00000033800.91810.97160941.867600.943102.985501.70490K562HNRNPA2B1
PIAS1ENSG00000033800.91640.097702101.71810-0.357803.191702.34080K562HSPD1
PIAS1ENSG00000033800.91596.464101268.129400.332102.160901.44260K562KIF1C
PIAS1ENSG00000033800.9636.14310804.82720-0.339302.545001.66340K562MATR3
PIAS1ENSG00000033800.91091.418901269.22620-0.217702.027501.33040K562MTPAP
PIAS1ENSG00000033800.91546.96490995.751200.635505.088903.77080K562NAA15
PIAS1ENSG00000033800.91418.523201759.59490-0.310902.368901.61120K562PPIG
PIAS1ENSG00000033800.9736.29370921.49990-0.323702.218601.41610K562PSIP1
PIAS1ENSG00000033800.91893.235601185.077100.675808.917807.99040K562PUS1
PIAS1ENSG00000033800.91806.544901154.640800.6457011.8836010.65930K562RBM15
PIAS1ENSG00000033800.91517.02300752.553601.011303.209701.88960K562SF1
PIAS1ENSG00000033800.91886.35130864.799201.125103.779402.25940K562SNRNP200
PIAS1ENSG00000033800.9552.80180777.38290-0.491903.797102.96230K562TARDBP
PIAS1ENSG00000033800.91008.88720725.899800.474803.322902.10070K562U2AF1
PIAS1ENSG00000033800.91121.71770749.755600.581107.447606.13270K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PIAS1 is not available on ENCORE database.





4 RBPs can affect the splicing of PIAS1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPIAS1ENSG00000033800.9chr15+684759676847600568473549684736926847987968480402-0.282000.000020.00067excludedK562SF3B4
SEPIAS1ENSG00000033800.9chr15+684759676847600568473549684736926847987968480402-0.428000.000000.00000excludedK562AQR
SEPIAS1ENSG00000033800.9chr15+684759676847600568473549684736926847987968480402-0.105000.000880.03616excludedK562SF3B1
A3SSPIAS1ENSG00000033800.9chr15+6843887668439038684389036843903868438153684382440.061000.000130.00112longerK562AQR
A3SSPIAS1ENSG00000033800.9chr15+6843459768434675684346276843467568434283684343680.072000.001930.01248longerK562AQR
A3SSPIAS1ENSG00000033800.9chr15+6846876068468992684688116846899268467974684681050.071000.000000.00001longerK562AQR
MXEPIAS1ENSG00000033800.9chr15+68434627684346756843815368438244684342836843436868438903684390380.124000.002080.037101includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PIAS1 is not avaliable on ENCORE database.