INVS

General Information

Gene Name       : INVS
Gene ID             : ENSG00000119509.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: INVS)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878INVSENSG00000119509.127.228.848.03ENCSR000AEF
HepG2INVSENSG00000119509.127.869.478.67ENCSR985KAT
K562INVSENSG00000119509.125.936.736.33ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for INVS is not avaliable on ENCORE database.



Proteins bound to RNA
  • INVS RNA is bound by 22 proteins.  







eCLIP assay for INVS is not avaliable on ENCORE database.





22 proteins are bound to INVS RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr9102893145102893251+3'-UTR,intron-Distal3.601235.30252HepG2KHSRP
chr9102893155102893257+3'-UTR,intron-Distal5.4968610.83219K562KHSRP
chr9102893003102893069+3'-UTR,intron-Distal4.227244.29306HepG2KHSRP
chr9102888663102888741+5'-UTR,CDS,intron-Proximal4.832516.78401HepG2GRWD1
chr9102861570102861702+5'-UTR,intron-Proximal3.538684.88807HepG2NCBP2
chr9102888741102888824+5'-UTR,CDS3.859806.84754HepG2GRWD1
chr9102866838102866910+5'-UTR,CDS,intron-Proximal4.404303.80193HepG2GRWD1
chr9102888663102888790+5'-UTR,CDS,intron-Proximal4.311747.79455HepG2PPIG
chr9102888722102888845+5'-UTR,CDS,intron-Proximal3.2296211.44176HepG2BCLAF1
chr9102888784102888917+5'-UTR,CDS,intron-Proximal4.453505.10338HepG2KHSRP
chr9103059198103059231+CDS,intron-Proximal3.354184.31744K562YBX3
chr9103014570103014632+CDS3.099414.79538HepG2BCLAF1
chr9103027103103027136+CDS,intron-Proximal4.461593.89826HepG2BCLAF1
chr9103015234103015271+CDS4.406384.34038HepG2BCLAF1
chr9103015317103015410+CDS3.521319.28980HepG2BCLAF1
chr9102991958102991999+CDS3.723044.51739HepG2BCLAF1
chr9103055306103055320+CDS4.538306.09204K562YBX3
chr9103055320103055326+CDS,intron-Proximal4.524296.09204K562YBX3
chr9103055303103055306+CDS4.404005.20509K562YBX3
chr9103004920103004960+CDS3.723044.51739HepG2BCLAF1
chr9102864106102864219+intron-Distal4.876886.45599K562PRPF8
chr9102937580102937678+intron-Distal3.498775.35818K562SAFB2
chr9102901563102901687+intron-Distal3.939834.19039HepG2PTBP1
chr9103061792103061872+intron-Distal3.725643.51804HepG2HNRNPL
chr9102901612102901659+intron-Distal4.455775.04993HepG2QKI
chr9102964832102964941+intron-Distal5.8594228.74200K562PTBP1
chr9102867750102867820+intron-Distal4.422344.74221HepG2PTBP1
chr9102952823102952868+intron-Distal3.243953.91859HepG2SUGP2
chr9102893284102893351+intron-Distal3.905745.61949K562KHSRP
chr9102954544102954630+intron-Distal3.439384.65797K562TARDBP
chr9102952050102952086+intron-Distal3.931733.24322HepG2MATR3
chr9102950745102950796+intron-Distal4.553574.48560K562EXOSC5
chr9102953320102953370+intron-Distal4.493154.31720HepG2MATR3
chr9102921928102921982+intron-Distal4.318463.50357HepG2QKI
chr9102909405102909636+intron-Distal3.140686.71344HepG2HNRNPL
chr9102954500102954557+intron-Distal3.572253.12825K562EIF4G2
chr9103061897103062020+intron-Distal3.364954.26114HepG2HNRNPL
chr9102901723102901828+intron-Distal4.748376.76922HepG2PTBP1
chr9102907100102907222+intron-Distal3.429123.29499HepG2PRPF4
chr9102897399102897443+intron-Distal3.720303.02234K562KHSRP
chr9103061808103061884+intron-Distal4.199064.71638K562HNRNPL
chr9102867877102867988+intron-Distal4.711035.30852HepG2HNRNPL
chr9102896013102896088+intron-Distal3.785829.12799HepG2HNRNPL
chr9102952299102952354+intron-Distal4.288133.27946HepG2HNRNPM
chr9102951557102951622+intron-Distal4.951866.73731K562EXOSC5
chr9102864105102864182+intron-Distal4.284596.48405K562AQR
chr9103000869103000969+intron-Distal3.959253.27829HepG2MATR3
chr9102953152102953194+intron-Distal3.579754.61322HepG2MATR3
chr9102950931102950985+intron-Distal3.199933.00129HepG2SUGP2
chr9102893420102893480+intron-Distal3.383485.36861HepG2U2AF2
chr9102864837102864925+intron-Distal3.426004.74790HepG2ILF3
chr9102964836102964918+intron-Distal6.8752428.81672HepG2PTBP1
chr9102954319102954368+intron-Distal3.985843.79098HepG2SUGP2
chr9102952048102952095+intron-Distal4.1444510.31219K562EXOSC5
chr9102935235102935360+intron-Distal3.569955.56248K562SAFB2
chr9102896023102896094+intron-Distal4.418504.27660K562HNRNPL
chr9102950582102950632+intron-Distal4.719036.08869K562EXOSC5
chr9102911147102911264+intron-Distal3.714913.06150K562KHSRP
chr9102986514102986571+intron-Distal3.302773.06005HepG2QKI
chr9103061943103062000+intron-Distal4.505384.30270K562AGGF1
chr9102952193102952232+intron-Distal4.385064.48560K562EXOSC5
chr9102929818102929917+intron-Distal3.238194.01234HepG2HNRNPL
chr9102962054102962102+intron-Distal3.685053.04224HepG2SUGP2
chr9102888831102888916+intron-Proximal4.234824.89208K562AQR
chr9102888867102888898+intron-Proximal3.008143.55800HepG2BCLAF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for INVS is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for INVS is not available on ENCORE database.

  • 41 RBPs can affect the levels of INVS.  








The Knockdown/knockout RNA-Seq assay for INVS is not available on ENCORE database.





41 RBPs can affect the gene expression of INVS :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
INVSENSG00000119509.8325.85530439.50380-0.431602.122401.42960HepG2ASCC1
INVSENSG00000119509.8234.26130321.13570-0.455102.176401.64060HepG2BOP1
INVSENSG00000119509.8316.10170398.93110-0.335802.102801.51150HepG2CKAP4
INVSENSG00000119509.8238.07070452.11020-0.925305.805804.83440HepG2EIF4B
INVSENSG00000119509.8276.25450389.90950-0.497103.074602.19730HepG2EWSR1
INVSENSG00000119509.8292.36530440.04440-0.589903.608502.81700HepG2HNRNPK
INVSENSG00000119509.8228.61630346.44030-0.599704.583003.81900HepG2HNRNPU
INVSENSG00000119509.8469.97190363.572700.370201.923801.31160HepG2IGF2BP1
INVSENSG00000119509.8267.09600471.28940-0.819305.619904.74610HepG2MATR3
INVSENSG00000119509.8350.83910469.73420-0.421001.867701.40110HepG2PTBP1
INVSENSG00000119509.8314.61840502.14750-0.674506.108805.41290HepG2RBM22
INVSENSG00000119509.8396.98870280.582200.500602.242901.52260HepG2RPS3A
INVSENSG00000119509.8155.82820237.90250-0.610402.439301.69700HepG2RRP9
INVSENSG00000119509.8385.90450308.516700.322801.875401.32800HepG2SAFB2
INVSENSG00000119509.8349.11210489.15050-0.486602.036201.51700HepG2SF3B4
INVSENSG00000119509.8468.33630567.14930-0.276201.773601.34520HepG2SRFBP1
INVSENSG00000119509.8335.97090450.80940-0.424202.864802.22790HepG2SRSF5
INVSENSG00000119509.8690.94360492.406100.488604.964804.31690HepG2SSB
INVSENSG00000119509.8371.50350469.75610-0.338502.175201.63090HepG2UTP3
INVSENSG00000119509.8765.98260535.124200.517307.003306.23750HepG2ZNF622
INVSENSG00000119509.8371.02540512.75860-0.466802.529701.59710K562AKAP8
INVSENSG00000119509.8308.21990485.61020-0.655803.522702.78200K562AKAP8L
INVSENSG00000119509.8242.33840484.48560-0.999409.356908.38070K562AQR
INVSENSG00000119509.8365.46410509.48360-0.479302.517401.64840K562ATP5C1
INVSENSG00000119509.8610.80310487.591500.324902.371501.76090K562DDX47
INVSENSG00000119509.8380.56340522.67890-0.457802.134501.37650K562DKC1
INVSENSG00000119509.8209.22770319.10930-0.609004.137003.41890K562FXR1
INVSENSG00000119509.8158.53950300.79660-0.923906.278705.41470K562HNRNPC
INVSENSG00000119509.8367.28380515.42510-0.488902.361201.60770K562KIF1C
INVSENSG00000119509.8352.69450493.33080-0.484102.578901.55450K562MAK16
INVSENSG00000119509.8412.96520577.39630-0.483502.623701.74200K562MBNL1
INVSENSG00000119509.8275.44670404.70680-0.555102.680001.81360K562NAA15
INVSENSG00000119509.8218.86040306.43780-0.485602.628701.42970K562NCBP2
INVSENSG00000119509.8158.37030271.72180-0.778804.457503.20830K562PCBP2
INVSENSG00000119509.8109.31940219.25990-1.004105.080204.06530K562PRPF8
INVSENSG00000119509.8171.34150296.67480-0.792005.847904.91180K562PTBP1
INVSENSG00000119509.8550.27590729.51090-0.406802.841402.01400K562PUF60
INVSENSG00000119509.8312.98550469.26010-0.584303.220602.58830K562RBM15
INVSENSG00000119509.8198.38400284.53750-0.520302.668301.84360K562RBM22
INVSENSG00000119509.8149.65400236.24930-0.658702.794701.81600K562SF3B1
INVSENSG00000119509.8133.30640258.24290-0.954007.184805.76530K562SF3B4
INVSENSG00000119509.8177.48890358.80750-1.015504.168702.55230K562SNRNP200
INVSENSG00000119509.8306.37300407.94590-0.413102.673101.75000K562SRPK2
INVSENSG00000119509.8208.38090294.36380-0.498402.387101.72740K562TARDBP
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for INVS is not available on ENCORE database.





17 RBPs can affect the splicing of INVS :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEINVSENSG00000119509.8chr9+1030142491030143751030088861030090691030145641030147200.385000.000070.02085includedK562HNRNPA1
SEINVSENSG00000119509.8chr9+102977206102977322102888664102888831102988343102988517-0.066000.006080.07214excludedK562PUS1
SEINVSENSG00000119509.8chr9+1029776821029777701028886641028888311029883431029885170.421000.000000.00018includedHepG2SFPQ
SEINVSENSG00000119509.8chr9+1030037331030038381030023411030025221030048511030049610.134000.001920.06778includedHepG2MATR3
SEINVSENSG00000119509.8chr9+1028941511028942361028886641028888311029883431029885170.441000.001220.07698includedHepG2HNRNPL
SEINVSENSG00000119509.8chr9+1028941511028942361028886641028888311029883431029885170.311000.000780.05335includedK562HNRNPL
SEINVSENSG00000119509.8chr9+1028941511028942361028886641028888311029883431029885170.240000.000400.08450includedK562PPIL4
SEINVSENSG00000119509.8chr9+102977682102977770102888664102888831102988343102988516-0.431000.000290.06079excludedK562FXR2
SEINVSENSG00000119509.8chr9+102977682102977770102888664102888831102988343102988516-0.220000.001830.03258excludedK562U2AF2
SEINVSENSG00000119509.8chr9+1030142491030143751030088861030090691030145641030147200.596000.000000.00013includedK562HNRNPU
SEINVSENSG00000119509.8chr9+102977682102977770102888664102888831102988343102988517-0.198000.001420.03654excludedK562AGGF1
SEINVSENSG00000119509.8chr9+1030142491030143751030088861030090691030145641030147200.258000.000030.00335includedHepG2SRSF9
SEINVSENSG00000119509.8chr9+1030037331030038381030023411030025221030048511030049610.353000.001590.05761includedK562PTBP1
A3SSINVSENSG00000119509.8chr9+1030351251030353581030351451030353581030271031030272100.184000.019820.09466longerK562AQR
RIINVSENSG00000119509.8chr9+1030546071030553251030546071030547181030552281030553250.193000.004730.03260includedHepG2U2AF2
RIINVSENSG00000119509.8chr9+103054607103055325103054607103054718103055228103055325-0.610000.000750.01898excludedK562SRSF1
RIINVSENSG00000119509.8chr9+103054607103055325103054607103054718103055228103055325-0.280000.004060.04683excludedHepG2PCBP1
RIINVSENSG00000119509.8chr9+103054607103055325103054607103054718103055228103055325-0.443000.000010.00037excludedHepG2SRSF1
MXEINVSENSG00000119509.8chr9+103008897103009069103014249103014375103004851103004961103014564103014720-0.502000.000910.056432includedK562LARP4
MXEINVSENSG00000119509.8chr9+1030058401030059601030088861030090691030048511030049611030145641030147200.315000.000940.025701includedHepG2HNRNPK
MXEINVSENSG00000119509.8chr9+1030058401030059601030088971030090691030048511030049611030145641030147200.238000.000140.005631includedHepG2HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for INVS is not avaliable on ENCORE database.