GTSF1

General Information

Gene Name : GTSF1
Gene ID : ENSG00000170627.10
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: GTSF1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	GTSF1	ENSG00000170627.10	121.42	99.43	110.43	ENCSR000AEF
HepG2	GTSF1	ENSG00000170627.10	0.00	0.00	0.00	ENCSR985KAT
K562	GTSF1	ENSG00000170627.10	365.86	395.40	380.63	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

GeneName	Cell_Line	Method	Sample_reps	Control_reps	KD%	Status	Project
GTSF1	Ribo-STAMP-293T	shRNA	BGRSLV03-33,BGRSLV03-34	BGRSLV03-1,BGRSLV03-2		NotSatisfied	ENCORE2
GTSF1	Ribo-STAMP-293T	shRNA	BGRSLV07-11,BGRSLV07-12	BGRSLV07-1,BGRSLV07-2		NotSatisfied	ENCORE2
GTSF1	293T	shRNA	GTSF1-BG293LV02-19,GTSF1-BG293LV02-20	NT-BG293LV02-1,NT-BG293LV02-2	,	Revoked	ENCORE2
GTSF1	293T	shRNA	GTSF1-BG293LV06-23,GTSF1-BG293LV06-24	NT-BG293LV06-1,NT-BG293LV06-2	,	Sequenced	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for GTSF1 is not avaliable on ENCORE database.

Proteins bound to RNA

GTSF1 RNA is bound by 17 proteins.

eCLIP assay for GTSF1 is not avaliable on ENCORE database.

17 proteins are bound to GTSF1 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr12	54849909	54849948	-	3'-UTR,intron-Distal,intron-Proximal	4.07711	13.41431	K562	U2AF2
chr12	54852872	54852890	-	3'-UTR,intron-Distal,intron-Proximal	4.37218	7.97356	K562	IGF2BP1
chr12	54849745	54849822	-	3'-UTR,intron-Distal	4.83405	20.25522	K562	IGF2BP1
chr12	54849900	54849938	-	3'-UTR,intron-Distal,intron-Proximal	4.98312	13.83696	K562	IGF2BP1
chr12	54852904	54852909	-	3'-UTR,CDS,intron-Distal	3.29466	8.60308	K562	YBX3
chr12	54852872	54852902	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.37404	8.05355	K562	PABPC4
chr12	54849825	54849882	-	3'-UTR,intron-Distal,intron-Proximal	5.10985	28.79278	K562	IGF2BP1
chr12	54849896	54849951	-	3'-UTR,intron-Distal,intron-Proximal	4.09438	11.31129	K562	U2AF1
chr12	54852872	54852886	-	3'-UTR,intron-Distal,intron-Proximal	3.23502	5.04716	K562	SND1
chr12	54865016	54865043	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.93651	27.92267	K562	YBX3
chr12	54865027	54865043	-	5'-UTR,CDS,intron-Distal	3.35118	13.09014	K562	DDX3X
chr12	54865034	54865061	-	5'-UTR,intron-Distal	5.50015	16.75154	HepG2	SUB1
chr12	54867329	54867371	-	5'-UTR,intron-Distal,intron-Proximal	3.30968	10.48121	K562	DDX3X
chr12	54865043	54865062	-	5'-UTR,intron-Distal,intron-Proximal	3.51363	9.35807	K562	DDX3X
chr12	54867328	54867355	-	5'-UTR,intron-Distal,intron-Proximal	5.47812	15.77869	HepG2	SUB1
chr12	54856446	54856502	-	CDS,intron-Distal	3.83720	5.89423	K562	SND1
chr12	54856997	54857081	-	CDS,intron-Distal	3.21004	7.67013	K562	SND1
chr12	54865015	54865027	-	CDS,intron-Distal,intron-Proximal	3.18527	14.69203	K562	DDX3X
chr12	54858850	54858899	-	CDS,intron-Distal,intron-Proximal	4.31872	7.36912	K562	SND1
chr12	54854227	54854245	-	CDS,intron-Distal	4.93866	23.05167	K562	YBX3
chr12	54858855	54858903	-	CDS,intron-Distal	4.58963	37.10291	K562	YBX3
chr12	54855847	54855898	-	CDS,intron-Distal,intron-Proximal	3.71548	6.32052	K562	AQR
chr12	54857012	54857057	-	CDS,intron-Distal	3.14913	18.62311	K562	YBX3
chr12	54858907	54858955	-	CDS,intron-Distal,intron-Proximal	3.97020	7.23394	K562	RPS3
chr12	54854159	54854231	-	CDS,intron-Distal,intron-Proximal	3.10660	5.31499	K562	IGF2BP1
chr12	54854164	54854227	-	CDS,intron-Distal	3.90374	5.64799	K562	IGF2BP2
chr12	54856442	54856457	-	CDS,intron-Distal	3.96274	14.45786	K562	YBX3
chr12	54856466	54856472	-	CDS,intron-Distal	3.69468	23.55755	K562	YBX3
chr12	54856980	54857076	-	CDS,intron-Distal	3.18019	3.92909	K562	GRWD1
chr12	54858850	54858854	-	CDS,intron-Distal,intron-Proximal	3.67842	12.74366	K562	YBX3
chr12	54857057	54857081	-	CDS,intron-Distal	3.89468	18.83109	K562	YBX3
chr12	54856881	54856960	-	CDS,intron-Distal,intron-Proximal	3.82390	11.47097	K562	AQR
chr12	54858802	54858864	-	CDS,intron-Distal,intron-Proximal	4.93262	4.48002	K562	AQR
chr12	54856497	54856509	-	CDS,intron-Distal	3.40789	18.17574	K562	YBX3
chr12	54854245	54854255	-	CDS,intron-Distal	4.18466	14.88203	K562	YBX3
chr12	54858911	54858928	-	CDS,intron-Distal	4.65177	27.32401	K562	YBX3
chr12	54857042	54857142	-	CDS,intron-Distal,intron-Proximal	3.52097	16.76647	K562	SF3B4
chr12	54857012	54857059	-	CDS,intron-Distal	3.90571	3.03355	K562	METAP2
chr12	54858948	54858951	-	CDS,intron-Distal	3.80399	21.28472	K562	YBX3
chr12	54854072	54854185	-	CDS,intron-Distal,intron-Proximal	3.40489	8.18888	K562	AQR
chr12	54858928	54858948	-	CDS,intron-Distal	3.85782	26.06833	K562	YBX3
chr12	54854230	54854255	-	CDS,intron-Distal	3.62622	5.04716	K562	SND1
chr12	54856484	54856497	-	CDS,intron-Distal	3.60595	25.99114	K562	YBX3
chr12	54854199	54854225	-	CDS,intron-Distal	4.43401	21.94366	K562	YBX3
chr12	54854178	54854199	-	CDS,intron-Distal	4.21381	19.31287	K562	YBX3
chr12	54854160	54854178	-	CDS,intron-Distal,intron-Proximal	3.66005	11.53103	K562	YBX3
chr12	54856472	54856484	-	CDS,intron-Distal	3.61718	24.58573	K562	YBX3
chr12	54856457	54856466	-	CDS,intron-Distal	3.20443	13.80568	K562	YBX3
chr12	54855892	54855910	-	CDS,intron-Distal,intron-Proximal	3.50319	13.48472	K562	YBX3
chr12	54857020	54857078	-	CDS,intron-Distal	3.77823	5.16549	HepG2	SUB1
chr12	54867003	54867120	-	intron-Distal	3.85369	6.19377	K562	KHSRP
chr12	54856378	54856408	-	intron-Distal,intron-Proximal	4.84233	4.48002	K562	AQR
chr12	54854039	54854127	-	intron-Distal,intron-Proximal	6.23047	17.20896	K562	PRPF8
chr12	54853971	54854038	-	intron-Distal	3.99691	4.93376	K562	PRPF8
chr12	54855818	54855886	-	intron-Distal,intron-Proximal	3.07163	3.20348	K562	PRPF8
chr12	54852747	54852847	-	intron-Distal,intron-Proximal	4.87250	4.03304	K562	RBM22
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for GTSF1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for GTSF1 is not available on ENCORE database.
34 RBPs can affect the levels of GTSF1.

The Knockdown/knockout RNA-Seq assay for GTSF1 is not available on ENCORE database.

34 RBPs can affect the gene expression of GTSF1 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
GTSF1	ENSG00000170627.5	3728.49380	3013.28220	0.30720	2.86670	1.66220	K562	AARS
GTSF1	ENSG00000170627.5	3081.72590	5839.01980	-0.92200	24.64700	21.08800	K562	APOBEC3C
GTSF1	ENSG00000170627.5	3091.47760	5098.78060	-0.72190	12.88510	11.75230	K562	AQR
GTSF1	ENSG00000170627.5	2692.11290	3141.74820	-0.22280	2.85200	1.87710	K562	BCLAF1
GTSF1	ENSG00000170627.5	4201.07730	4892.36920	-0.21980	2.60410	1.53110	K562	CPEB4
GTSF1	ENSG00000170627.5	3421.12650	4036.14930	-0.23850	2.19490	1.48900	K562	CPSF6
GTSF1	ENSG00000170627.5	1745.30890	2536.06500	-0.53910	6.07220	4.67500	K562	EFTUD2
GTSF1	ENSG00000170627.5	4758.66640	6617.43340	-0.47570	11.47190	9.62100	K562	EIF4G2
GTSF1	ENSG00000170627.5	2496.07090	3025.47040	-0.27750	2.65970	1.42020	K562	EXOSC5
GTSF1	ENSG00000170627.5	4766.29600	3934.18070	0.27670	2.37320	1.58810	K562	FIP1L1
GTSF1	ENSG00000170627.5	3348.42420	4106.46970	-0.29440	2.41830	1.61640	K562	FMR1
GTSF1	ENSG00000170627.5	2370.99280	3480.50950	-0.55380	6.16750	4.74940	K562	FTO
GTSF1	ENSG00000170627.5	2997.44610	3853.61870	-0.36250	3.91010	2.97210	K562	GPKOW
GTSF1	ENSG00000170627.5	2576.88930	3295.96660	-0.35510	4.08150	3.37280	K562	HNRNPC
GTSF1	ENSG00000170627.5	1535.18720	3578.58220	-1.22100	26.86930	23.34290	K562	HNRNPK
GTSF1	ENSG00000170627.5	3298.65330	4575.14030	-0.47190	6.81680	5.08270	K562	HNRNPL
GTSF1	ENSG00000170627.5	4226.53250	3235.95730	0.38520	3.13210	2.13650	K562	HNRNPM
GTSF1	ENSG00000170627.5	7367.18150	5333.86120	0.46580	5.83490	4.69320	K562	HSPD1
GTSF1	ENSG00000170627.5	5385.99000	7053.43780	-0.38910	3.41680	2.16100	K562	MSI2
GTSF1	ENSG00000170627.5	2718.33470	3748.16050	-0.46350	11.69170	10.16010	K562	MTPAP
GTSF1	ENSG00000170627.5	3334.35270	4164.38000	-0.32070	9.11690	7.86900	K562	NSUN2
GTSF1	ENSG00000170627.5	2709.18720	3350.50510	-0.30650	2.93410	1.92790	K562	PCBP2
GTSF1	ENSG00000170627.5	2873.75390	3848.37990	-0.42130	3.79360	2.82040	K562	PCBP3
GTSF1	ENSG00000170627.5	2355.23270	2951.77630	-0.32570	3.73600	2.79980	K562	POLR2G
GTSF1	ENSG00000170627.5	5819.51520	7220.04830	-0.31110	3.63000	2.69810	K562	PUF60
GTSF1	ENSG00000170627.5	6434.40370	7524.52010	-0.22580	3.16350	2.13860	K562	PUM2
GTSF1	ENSG00000170627.5	2725.32270	3508.02470	-0.36420	3.60970	2.63860	K562	RBM22
GTSF1	ENSG00000170627.5	3341.47560	4109.42270	-0.29850	4.48510	3.46650	K562	SF3A3
GTSF1	ENSG00000170627.5	2836.10390	3664.60250	-0.36970	2.84780	1.85960	K562	SF3B1
GTSF1	ENSG00000170627.5	3375.40600	4210.21420	-0.31880	7.20160	5.76760	K562	SRPK2
GTSF1	ENSG00000170627.5	2270.62650	3629.95300	-0.67690	9.83520	8.37230	K562	TARDBP
GTSF1	ENSG00000170627.5	3945.08480	4415.59330	-0.16260	1.95190	1.34090	K562	UPF1
GTSF1	ENSG00000170627.5	2837.34060	3778.26270	-0.41320	5.35610	4.11630	K562	WDR3
GTSF1	ENSG00000170627.5	4602.58960	5743.97360	-0.31960	3.24490	2.30160	K562	ZC3H8
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for GTSF1 is not available on ENCORE database.

15 RBPs can affect the splicing of GTSF1 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	GTSF1	ENSG00000170627.5	chr12	-	54858850	54858951			54856954	54857081	54865016	54865061	0.05700	0.00000	0.00000	included	K562	SRSF1
SE	GTSF1	ENSG00000170627.5	chr12	-	54865016	54865061			54856954	54857081	54867329	54867383	-0.14300	0.00153	0.02952	excluded	K562	SRSF1
SE	GTSF1	ENSG00000170627.5	chr12	-	54858850	54858951			54856954	54857081	54867329	54867383	-0.05600	0.00000	0.00013	excluded	K562	SF3B4
SE	GTSF1	ENSG00000170627.5	chr12	-	54858850	54858951			54856954	54857081	54865016	54865061	-0.05200	0.00001	0.00016	excluded	K562	AQR
SE	GTSF1	ENSG00000170627.5	chr12	-	54858850	54858951			54856954	54857081	54865016	54865061	0.05500	0.00000	0.00001	included	K562	FXR1
SE	GTSF1	ENSG00000170627.5	chr12	-	54858850	54858951			54856954	54857081	54867329	54867383	-0.07000	0.00000	0.00000	excluded	K562	PUS1
SE	GTSF1	ENSG00000170627.5	chr12	-	54858850	54858951			54856954	54857081	54865016	54865061	-0.09400	0.00000	0.00002	excluded	K562	LARP4
SE	GTSF1	ENSG00000170627.5	chr12	-	54858850	54858951			54856954	54857081	54865016	54865061	-0.12100	0.00000	0.00000	excluded	K562	U2AF1
SE	GTSF1	ENSG00000170627.5	chr12	-	54858850	54858951			54856954	54857081	54865016	54865061	-0.05900	0.00007	0.01029	excluded	K562	HNRNPUL1
SE	GTSF1	ENSG00000170627.5	chr12	-	54858850	54858951			54856954	54857081	54867329	54867383	-0.05100	0.00001	0.00092	excluded	K562	UTP18
SE	GTSF1	ENSG00000170627.5	chr12	-	54858850	54858951			54856954	54857081	54865016	54865061	-0.10900	0.00000	0.00000	excluded	K562	U2AF2
SE	GTSF1	ENSG00000170627.5	chr12	-	54865016	54865061			54856954	54857081	54867329	54867383	-0.10000	0.00006	0.00309	excluded	K562	RBM15
SE	GTSF1	ENSG00000170627.5	chr12	-	54865016	54865061			54856954	54857081	54867329	54867383	-0.06800	0.00140	0.03611	excluded	K562	AGGF1
SE	GTSF1	ENSG00000170627.5	chr12	-	54858850	54858951			54856954	54857081	54865016	54865061	0.05200	0.00001	0.00105	included	K562	HNRNPK
SE	GTSF1	ENSG00000170627.5	chr12	-	54865016	54865061			54856954	54857081	54867329	54867383	-0.23200	0.00015	0.01017	excluded	K562	HNRNPK
SE	GTSF1	ENSG00000170627.5	chr12	-	54858850	54858951			54856954	54857081	54865016	54865061	-0.07100	0.00001	0.00539	excluded	K562	NPM1
A3SS	GTSF1	ENSG00000170627.5	chr12	-	54854160	54854275			54854160	54854255	54855892	54855988	0.12400	0.00000	0.00000	longer	K562	AQR
MXE	GTSF1	ENSG00000170627.5	chr12	-	54854160	54854255	54855892	54855956	54852872	54852909	54856425	54856509	-0.06100	0.00342	0.04231	2included	K562	DROSHA
MXE	GTSF1	ENSG00000170627.5	chr12	-	54852872	54852909	54854208	54854275	54849922	54849937	54855892	54855956	0.07700	0.00000	0.00000	1included	K562	AQR
MXE	GTSF1	ENSG00000170627.5	chr12	-	54852872	54852909	54854160	54854275	54849922	54849937	54855892	54855956	0.09000	0.00000	0.00000	1included	K562	AQR
MXE	GTSF1	ENSG00000170627.5	chr12	-	54858850	54859022	54865016	54865120	54856954	54857081	54867329	54867354	0.05400	0.00020	0.00222	1included	K562	AQR
MXE	GTSF1	ENSG00000170627.5	chr12	-	54858850	54859022	54865016	54865061	54856954	54857081	54867329	54867354	0.06900	0.00016	0.00187	1included	K562	AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

GTSF1

General Information

Functions

Localization

Domains (AlphaFold: GTSF1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for GTSF1 is not avaliable on ENCORE database.

17 proteins are bound to GTSF1 RNA:

eCLIP assay for GTSF1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for GTSF1 is not available on ENCORE database.

34 RBPs can affect the gene expression of GTSF1 :

The Knockdown/knockout RNA-Seq assay for GTSF1 is not available on ENCORE database.

15 RBPs can affect the splicing of GTSF1 :

The Knockdown/knockout RNA-Seq assay for GTSF1 is not avaliable on ENCORE database.