FBXL20

General Information

Gene Name       : FBXL20
Gene ID             : ENSG00000108306.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FBXL20)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FBXL20ENSG00000108306.123.122.472.79ENCSR000AEF
HepG2FBXL20ENSG00000108306.124.616.475.54ENCSR985KAT
K562FBXL20ENSG00000108306.124.504.234.37ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FBXL20 is not avaliable on ENCORE database.



Proteins bound to RNA
  • FBXL20 RNA is bound by 22 proteins.  







eCLIP assay for FBXL20 is not avaliable on ENCORE database.





22 proteins are bound to FBXL20 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr173741720437417256-3'-UTR,intron-Distal3.985728.99604K562UPF1
chr173741548937415554-3'-UTR,intron-Distal3.6093522.25300K562UPF1
chr173741750437417563-3'-UTR,intron-Distal3.263113.40713K562HNRNPL
chr173741692137416972-3'-UTR,intron-Distal3.902318.37857K562UPF1
chr173741730737417366-3'-UTR,intron-Distal3.8768511.25148K562UPF1
chr173741695737417030-3'-UTR,intron-Distal3.710693.27788HepG2IGF2BP3
chr173755780837557895-5'-UTR,intron-Distal,intron-Proximal4.130728.13071HepG2NCBP2
chr173755784037557904-5'-UTR,intron-Distal,intron-Proximal3.091254.25828HepG2NKRF
chr173755783737557897-5'-UTR,intron-Distal,intron-Proximal4.214714.58989K562NONO
chr173745982137459891-CDS,intron-Distal,intron-Proximal4.108827.96049HepG2U2AF2
chr173742054637420632-CDS,intron-Distal4.147447.72847HepG2PPIG
chr173745731937457328-CDS,intron-Distal4.490505.05122K562DDX24
chr173745530237455336-CDS,intron-Distal3.578283.95068K562DDX24
chr173743906637439118-CDS,intron-Distal,intron-Proximal3.878165.18845HepG2U2AF2
chr173745732037457328-CDS,intron-Distal3.974705.40651HepG2PPIG
chr173745983737459878-CDS,intron-Distal,intron-Proximal4.025697.97611K562DDX24
chr173744173037441820-CDS,intron-Distal,intron-Proximal3.220614.29172K562YBX3
chr173743901837439101-CDS,intron-Distal3.395026.60490HepG2BCLAF1
chr173743765837437728-CDS,intron-Distal,intron-Proximal3.414183.76090HepG2U2AF2
chr173742045637420525-CDS,intron-Distal3.835343.14999HepG2GRWD1
chr173743905937439114-CDS,intron-Distal,intron-Proximal3.853203.95991K562U2AF2
chr173745525737455302-CDS,intron-Distal3.428504.70460K562DDX24
chr173742704737427108-CDS,intron-Distal,intron-Proximal5.774448.27639K562DDX24
chr173745983437459879-CDS,intron-Distal,intron-Proximal4.6966611.12920HepG2PPIG
chr173745525037455297-CDS,intron-Distal5.033785.68196HepG2BCLAF1
chr173742705137427114-CDS,intron-Distal,intron-Proximal3.380174.87883K562BUD13
chr173744176237441835-CDS,intron-Distal,intron-Proximal3.192384.57751HepG2U2AF2
chr173743765437437725-CDS,intron-Distal,intron-Proximal3.367515.12722K562BUD13
chr173745726037457277-CDS,intron-Distal4.130113.02457HepG2BCLAF1
chr173745982437459883-CDS,intron-Distal,intron-Proximal3.446734.35139K562U2AF1
chr173743764737437723-CDS,intron-Distal,intron-Proximal3.967598.05213K562U2AF2
chr173741562137415711-intron-Distal4.3158919.42884K562UPF1
chr173755716037557226-intron-Distal3.262823.84859K562NONO
chr173741619537416236-intron-Distal3.264427.30038K562FAM120A
chr173754152937541593-intron-Distal3.640255.37900K562TARDBP
chr173743788237437990-intron-Distal3.156363.28806K562KHSRP
chr173755704337557099-intron-Distal4.102653.71735K562TIA1
chr173743101637431120-intron-Distal4.281203.31283K562PRPF8
chr173741647437416515-intron-Distal4.264258.71030K562UPF1
chr173741641837416455-intron-Distal3.724439.72842K562UPF1
chr173755698337557103-intron-Distal3.628056.60059K562NONO
chr173755834537558408-intron-Distal3.500484.76224HepG2NKRF
chr173742739337427461-intron-Distal4.408863.77802HepG2U2AF2
chr173754145937541512-intron-Distal4.739307.00934K562TARDBP
chr173741680437416835-intron-Distal,intron-Proximal3.188256.74785K562UPF1
chr173741638137416418-intron-Distal4.2937010.12876K562UPF1
chr173745306437453166-intron-Distal4.767236.58335HepG2QKI
chr173741658537416644-intron-Distal3.994144.40891K562FAM120A
chr173747199537472139-intron-Distal3.707145.19856HepG2PTBP1
chr173741592237415972-intron-Distal4.568833.78860K562AKAP1
chr173743250137432578-intron-Distal4.891086.76922HepG2PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FBXL20 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FBXL20 is not available on ENCORE database.

  • 45 RBPs can affect the levels of FBXL20.  








The Knockdown/knockout RNA-Seq assay for FBXL20 is not available on ENCORE database.





45 RBPs can affect the gene expression of FBXL20 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FBXL20ENSG00000108306.7508.78740370.844000.456202.201501.72050HepG2AKAP1
FBXL20ENSG00000108306.7267.62490437.81220-0.710102.900002.28840HepG2BOP1
FBXL20ENSG00000108306.7205.09410307.94720-0.586404.477903.57140HepG2DAZAP1
FBXL20ENSG00000108306.7103.92920206.85920-0.993004.135202.59710HepG2DDX27
FBXL20ENSG00000108306.7490.50140355.284600.465202.518501.91940HepG2DDX3X
FBXL20ENSG00000108306.7378.86590280.535000.433402.766902.09330HepG2HNRNPL
FBXL20ENSG00000108306.7221.41080317.38820-0.519503.036202.27120HepG2ILF2
FBXL20ENSG00000108306.7354.40130487.67800-0.460502.096301.38130HepG2LARP4
FBXL20ENSG00000108306.7180.44310329.01060-0.866604.246703.48110HepG2MATR3
FBXL20ENSG00000108306.7248.95010324.15460-0.380802.040801.50690HepG2PCBP1
FBXL20ENSG00000108306.7457.72350316.160700.533702.032301.43590HepG2RPLP0
FBXL20ENSG00000108306.7218.20610322.66060-0.564303.139602.46140HepG2SMN1
FBXL20ENSG00000108306.7706.11780478.972300.559902.891702.09140HepG2SNRNP70
FBXL20ENSG00000108306.7693.00000490.442500.498705.386604.75100HepG2SRFBP1
FBXL20ENSG00000108306.7652.47640463.105600.494502.410101.48340HepG2SRSF3
FBXL20ENSG00000108306.7338.96330425.80020-0.329002.032601.57610HepG2SSB
FBXL20ENSG00000108306.7466.29120322.189500.533204.289603.61490HepG2TAF15
FBXL20ENSG00000108306.7198.71930304.62710-0.616303.846203.20380HepG2TRIM56
FBXL20ENSG00000108306.7214.64690338.96590-0.659203.237102.08760HepG2XRCC6
FBXL20ENSG00000108306.7142.39710216.64180-0.605402.107201.46650HepG2XRN2
FBXL20ENSG00000108306.71031.59330642.371700.683309.952208.96110K562AGGF1
FBXL20ENSG00000108306.7261.30070464.86570-0.831104.209702.62570K562APOBEC3C
FBXL20ENSG00000108306.7357.67630500.62350-0.485103.154101.77810K562CIRBP
FBXL20ENSG00000108306.7294.51040436.32340-0.567103.376002.66660K562DDX47
FBXL20ENSG00000108306.7144.47560219.57860-0.603902.521901.65310K562EFTUD2
FBXL20ENSG00000108306.7108.59840188.95740-0.799102.649201.67060K562EIF3A
FBXL20ENSG00000108306.7138.42220255.79380-0.885906.370805.18020K562EIF3G
FBXL20ENSG00000108306.7177.39760321.02180-0.855702.103101.56270K562FXR1
FBXL20ENSG00000108306.7508.79400278.240900.870604.030102.88730K562KRR1
FBXL20ENSG00000108306.7308.49400490.90320-0.670205.882204.64190K562MAGOH
FBXL20ENSG00000108306.7273.31360489.92470-0.842008.692306.95840K562MATR3
FBXL20ENSG00000108306.7890.20870556.973300.676403.867302.77620K562NAA15
FBXL20ENSG00000108306.7318.39760436.80320-0.456202.643401.68700K562PCBP2
FBXL20ENSG00000108306.7112.90410213.67530-0.920304.503203.54720K562PRPF8
FBXL20ENSG00000108306.7249.15330476.93460-0.9368010.569409.33030K562PTBP1
FBXL20ENSG00000108306.7438.74900574.82450-0.389702.276501.53720K562PUF60
FBXL20ENSG00000108306.7822.22780645.881200.348202.042701.51910K562RBM15
FBXL20ENSG00000108306.7354.71170481.31090-0.440302.468601.44590K562NELFE
FBXL20ENSG00000108306.7141.32580217.65280-0.623002.289501.54930K562RPS19
FBXL20ENSG00000108306.7408.37980552.29670-0.435502.244201.35190K562RPS3
FBXL20ENSG00000108306.7249.70060467.54210-0.904908.964107.70120K562SRSF1
FBXL20ENSG00000108306.7229.42590473.21080-1.0445010.629209.08910K562TARDBP
FBXL20ENSG00000108306.7315.90020456.45800-0.531003.773202.79670K562TIA1
FBXL20ENSG00000108306.7273.87040368.63480-0.428702.352101.61190K562U2AF2
FBXL20ENSG00000108306.7499.27470326.517300.612605.047903.84910K562WDR3
FBXL20ENSG00000108306.7650.72690418.032600.638304.360103.23660K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FBXL20 is not available on ENCORE database.





9 RBPs can affect the splicing of FBXL20 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFBXL20ENSG00000108306.7chr17-374417303744182637438981374391083745337937453448-0.476000.000000.00003excludedK562PUS1
SEFBXL20ENSG00000108306.7chr17-374417303744182637438981374391083745337937453448-0.334000.000690.01670excludedK562U2AF1
SEFBXL20ENSG00000108306.7chr17-3745928037459464374572533745732837459837374598920.489000.000250.02233includedHepG2HNRNPL
SEFBXL20ENSG00000108306.7chr17-3745928037459464374572533745732837459837374598920.358000.000000.00013includedK562HNRNPL
SEFBXL20ENSG00000108306.7chr17-3745725337457328374552423745533737459837374598920.063000.001460.08404includedK562HNRNPUL1
SEFBXL20ENSG00000108306.7chr17-374417303744182637438885374391083745337937453448-0.368000.000010.00054excludedK562UTP18
SEFBXL20ENSG00000108306.7chr17-374417303744182637438981374391083745337937453448-0.258000.004890.07119excludedK562U2AF2
SEFBXL20ENSG00000108306.7chr17-374417303744182637438981374391083745337937453448-0.193000.002150.04839excludedK562RBM15
SEFBXL20ENSG00000108306.7chr17-374417303744182637438981374391083745337937453448-0.379000.000000.00000excludedK562AGGF1
SEFBXL20ENSG00000108306.7chr17-374417303744182637438981374391083745337937453448-0.446000.001060.04498excludedHepG2HNRNPU
MXEFBXL20ENSG00000108306.7chr17-37441730374418263745337937453448374389813743910837455242374553370.199000.000920.034971includedK562AGGF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FBXL20 is not avaliable on ENCORE database.