ELP3

General Information

Gene Name       : ELP3
Gene ID             : ENSG00000134014.16
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: ELP3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ELP3ENSG00000134014.1631.3629.7530.55ENCSR000AEF
HepG2ELP3ENSG00000134014.1631.8439.8335.84ENCSR985KAT
K562ELP3ENSG00000134014.1634.3043.9139.10ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ELP3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ELP3 RNA is bound by 12 proteins.  







eCLIP assay for ELP3 is not avaliable on ENCORE database.





12 proteins are bound to ELP3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr82801786128017922+3'-UTR,CDS,intron-Proximal3.537596.06436HepG2BCLAF1
chr82804761628047678+3'-UTR3.429715.65632K562UPF1
chr82804762728047701+3'-UTR3.460704.53300K562LIN28B
chr82804810228048157+3'-UTR4.048236.14808K562UPF1
chr82804839828048449+3'-UTR3.685434.24288K562UPF1
chr82796423427964272+5'-UTR,CDS3.656344.34695HepG2BCLAF1
chr82796422727964290+5'-UTR,CDS,intron-Proximal3.236684.24993HepG2PPIG
chr82799533127995405+5'-UTR,CDS3.160453.24162HepG2G3BP1
chr82795475427954827+5'-UTR,CDS,intron-Distal3.349926.60490HepG2BCLAF1
chr82795744327957487+5'-UTR,CDS,intron-Distal,intron-Proximal4.313734.08604HepG2PPIG
chr82800938528009461+intron-Distal3.129096.35394HepG2SUGP2
chr82803334228033379+intron-Distal4.664736.05753HepG2SUGP2
chr82803177528031811+intron-Distal3.953773.79098HepG2SUGP2
chr82802552528025569+intron-Distal4.832635.72853HepG2HNRNPM
chr82800867328008737+intron-Distal3.799465.54651HepG2SUGP2
chr82800907928009138+intron-Distal4.742216.10726HepG2SUGP2
chr82800752428007588+intron-Distal3.715453.64762HepG2QKI
chr82799595727996156+intron-Distal3.312545.17344K562HNRNPL
chr82803908028039185+intron-Distal3.296253.69184HepG2SUGP2
chr82803100528031042+intron-Distal3.685053.04224HepG2SUGP2
chr82803650828036563+intron-Distal3.957213.86809HepG2SUGP2
chr82800747728007523+intron-Distal4.605704.78128HepG2SUGP2
chr82800883428008894+intron-Distal3.490777.20487HepG2SUGP2
chr82800878728008888+intron-Distal4.172293.68462HepG2MATR3
chr82799592327996001+intron-Distal3.227455.38424HepG2HNRNPL
chr82800913828009199+intron-Distal4.466604.51299HepG2SUGP2
chr82801550528015569+intron-Distal3.627034.19039HepG2PTBP1
chr82797681527976930+intron-Distal3.312056.14017HepG2HNRNPL
chr82803799328038029+intron-Distal3.767793.29248HepG2SUGP2
chr82800846628008505+intron-Distal3.053543.10640HepG2SUGP2
chr82803304328033081+intron-Distal3.016543.10883HepG2SUGP2
chr82800879728008892+intron-Distal3.101684.82768K562MATR3
chr82800999928010049+intron-Distal4.296254.78128HepG2SUGP2
chr82799765027997737+intron-Distal3.283403.93348K562TARDBP
chr82803256128032599+intron-Distal4.242794.36036HepG2SUGP2
chr82800703528007123+intron-Distal4.209553.90241K562MATR3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ELP3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ELP3 is not available on ENCORE database.

  • 70 RBPs can affect the levels of ELP3.  








The Knockdown/knockout RNA-Seq assay for ELP3 is not available on ENCORE database.





70 RBPs can affect the gene expression of ELP3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ELP3ENSG00000134014.121317.322401794.66540-0.446103.133102.57170HepG2AKAP1
ELP3ENSG00000134014.12900.103101484.95150-0.722308.147306.84350HepG2ASCC1
ELP3ENSG00000134014.121062.129401536.20010-0.532403.767902.61670HepG2CCAR1
ELP3ENSG00000134014.12642.63080816.56640-0.345602.364201.73060HepG2DDX21
ELP3ENSG00000134014.121240.635001719.18920-0.470603.895703.16450HepG2DDX3X
ELP3ENSG00000134014.121296.835001026.523100.337102.419901.47190HepG2DDX5
ELP3ENSG00000134014.12795.071601476.73540-0.8933010.232709.12560HepG2DDX6
ELP3ENSG00000134014.12658.51740805.15860-0.290102.209701.57410HepG2DNAJC21
ELP3ENSG00000134014.12642.82080798.09550-0.312103.085202.40260HepG2DNAJC2
ELP3ENSG00000134014.12841.935801419.70460-0.753808.592907.58400HepG2EIF2S1
ELP3ENSG00000134014.121249.031001568.98070-0.329001.917401.38110HepG2EIF4A3
ELP3ENSG00000134014.12888.722801527.54620-0.781406.686405.64920HepG2EIF4B
ELP3ENSG00000134014.121235.115801491.19690-0.271802.807902.20350HepG2ETF1
ELP3ENSG00000134014.12618.66580901.10060-0.542505.534004.34950HepG2EWSR1
ELP3ENSG00000134014.12743.007001071.29690-0.527903.194901.99200HepG2FUS
ELP3ENSG00000134014.12955.129201582.91420-0.728808.509507.35130HepG2FXR1
ELP3ENSG00000134014.12793.662601468.44900-0.8877010.964309.68170HepG2G3BP1
ELP3ENSG00000134014.121105.659301558.86320-0.495604.456503.31380HepG2G3BP2
ELP3ENSG00000134014.12441.17830636.57470-0.529002.647901.77240HepG2GEMIN5
ELP3ENSG00000134014.12462.149501086.01390-1.2326017.3382015.87430HepG2GPKOW
ELP3ENSG00000134014.12598.76990812.87280-0.441003.457602.74530HepG2HNRNPA1
ELP3ENSG00000134014.121002.168501220.00140-0.283802.677101.75470HepG2HNRNPA2B1
ELP3ENSG00000134014.121148.381801486.78830-0.372602.920802.20260HepG2HNRNPK
ELP3ENSG00000134014.12976.742901209.17720-0.308003.674902.90570HepG2HNRNPL
ELP3ENSG00000134014.12927.721501492.66900-0.686107.515606.45940HepG2IGF2BP2
ELP3ENSG00000134014.12793.401601400.71380-0.820003.281402.20810HepG2IGF2BP3
ELP3ENSG00000134014.121003.682601501.32740-0.580904.259802.99040HepG2KHSRP
ELP3ENSG00000134014.121137.078601621.88770-0.512303.712402.75010HepG2LARP4
ELP3ENSG00000134014.121219.493001583.46620-0.376802.652702.01010HepG2MAGOH
ELP3ENSG00000134014.121043.097301592.34850-0.610305.449104.58800HepG2MATR3
ELP3ENSG00000134014.12587.59650906.16960-0.625006.447805.26170HepG2MSI2
ELP3ENSG00000134014.12863.067801629.87330-0.9172011.9876010.71150HepG2NCBP2
ELP3ENSG00000134014.121039.222301316.29780-0.341003.279102.45100HepG2NOL12
ELP3ENSG00000134014.12801.215301451.58230-0.8574010.756709.35630HepG2PABPC4
ELP3ENSG00000134014.12965.771201484.51950-0.6202012.4073011.27100HepG2PCBP1
ELP3ENSG00000134014.12750.13670935.93560-0.319303.014402.21190HepG2PRPF4
ELP3ENSG00000134014.12931.486501510.56990-0.6975014.4370013.37890HepG2PTBP1
ELP3ENSG00000134014.121141.017601333.90400-0.225302.350001.79490HepG2PUM1
ELP3ENSG00000134014.121008.695501635.95100-0.6976012.6124011.42040HepG2QKI
ELP3ENSG00000134014.12826.932101484.74330-0.8444014.6227013.13880HepG2RBM25
ELP3ENSG00000134014.12825.894701681.10620-1.0254029.9446028.56440HepG2NELFE
ELP3ENSG00000134014.12846.688701565.74560-0.8869023.2105021.73030HepG2RECQL
ELP3ENSG00000134014.12502.55210695.58480-0.469002.317101.74920HepG2RPS19
ELP3ENSG00000134014.12705.06870893.83840-0.342302.229201.50670HepG2RPS2
ELP3ENSG00000134014.12824.838901572.67000-0.9310024.9346023.46120HepG2SF3B4
ELP3ENSG00000134014.121155.707201407.72730-0.284603.457802.91690HepG2SRFBP1
ELP3ENSG00000134014.121194.095901641.53850-0.459107.715307.01800HepG2SRSF1
ELP3ENSG00000134014.12977.056401240.68650-0.344603.887603.16740HepG2SRSF5
ELP3ENSG00000134014.12996.961101335.48890-0.421806.296305.52370HepG2SRSF9
ELP3ENSG00000134014.121146.717501410.97500-0.299203.652102.95610HepG2SUCLG1
ELP3ENSG00000134014.12367.19110833.50450-1.1827012.8238011.54610HepG2SUPV3L1
ELP3ENSG00000134014.121098.030001475.51080-0.426305.609904.86030HepG2TAF15
ELP3ENSG00000134014.12692.348601010.20500-0.545104.960904.03100HepG2TARDBP
ELP3ENSG00000134014.12832.626901355.75950-0.7034010.696109.08050HepG2TIA1
ELP3ENSG00000134014.12690.96100880.58180-0.349903.490502.87310HepG2TRIM56
ELP3ENSG00000134014.12874.112501227.63430-0.490005.096503.87330HepG2TUFM
ELP3ENSG00000134014.12362.04600492.41640-0.443702.245601.56150HepG2UCHL5
ELP3ENSG00000134014.12836.601601044.40800-0.320103.369202.72050HepG2UTP3
ELP3ENSG00000134014.12776.620801076.33230-0.470802.662601.62850HepG2XRCC6
ELP3ENSG00000134014.121069.290501367.86210-0.355304.560003.86340K562AGGF1
ELP3ENSG00000134014.121090.685101423.29550-0.384003.478802.74320K562AKAP8L
ELP3ENSG00000134014.121198.297501584.10900-0.402703.628302.97420K562AQR
ELP3ENSG00000134014.122260.622001643.525100.459808.661607.58920K562DDX47
ELP3ENSG00000134014.12559.190301065.84920-0.9306013.9240012.11470K562GPKOW
ELP3ENSG00000134014.121329.840001732.99130-0.382003.799202.91800K562GRSF1
ELP3ENSG00000134014.12897.835501456.35680-0.697803.284601.92230K562HNRNPA2B1
ELP3ENSG00000134014.121337.097701017.547200.393902.954401.67630K562HNRNPK
ELP3ENSG00000134014.12953.723001222.29500-0.358003.702402.66880K562HNRNPU
ELP3ENSG00000134014.121015.613401274.34740-0.327403.876902.93410K562MTPAP
ELP3ENSG00000134014.121174.086001415.90790-0.270203.664602.81880K562NSUN2
ELP3ENSG00000134014.12651.131001274.20210-0.968605.612604.06470K562PABPN1
ELP3ENSG00000134014.121086.775001375.34040-0.339703.616802.95170K562RBM15
ELP3ENSG00000134014.12579.56980859.74870-0.568904.192602.92010K562SUPV3L1
ELP3ENSG00000134014.12779.357901032.12520-0.405303.046402.30330K562TARDBP
ELP3ENSG00000134014.12690.43980904.23630-0.389202.715801.77960K562TRIM56
ELP3ENSG00000134014.121450.662601784.64620-0.298902.451101.64720K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ELP3 is not available on ENCORE database.





12 RBPs can affect the splicing of ELP3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEELP3ENSG00000134014.12chr8+279547352795483527950618279507502795734427957483-0.122000.001730.03286excludedK562SF3B4
SEELP3ENSG00000134014.12chr8+279654292796549327964229279643002796788627967955-0.089000.002040.03705excludedHepG2U2AF1
SEELP3ENSG00000134014.12chr8+2801730728017502280160842801615028017745280179730.108000.000000.00001includedK562AQR
SEELP3ENSG00000134014.12chr8+279547352795483527950618279507502795734427957483-0.122000.004090.03944excludedK562AQR
SEELP3ENSG00000134014.12chr8+279654292796549327964229279643002796788627967955-0.120000.000010.00017excludedK562AQR
SEELP3ENSG00000134014.12chr8+2801731128017502280160842801615028017745280179730.065000.001930.02913includedK562PUS1
SEELP3ENSG00000134014.12chr8+279547352795483527950618279507502795734427957483-0.155000.000110.00261excludedK562PUS1
SEELP3ENSG00000134014.12chr8+279654292796549327964229279643002796788627967955-0.159000.000010.00025excludedK562U2AF1
SEELP3ENSG00000134014.12chr8+2801730728017502280160842801615028017745280179730.108000.000360.01563includedK562UTP18
SEELP3ENSG00000134014.12chr8+279573442795748327954735279548352796422927964300-0.125000.005640.07967excludedK562U2AF2
SEELP3ENSG00000134014.12chr8+279654292796549327964229279643002796788627967955-0.093000.001550.02853excludedK562U2AF2
SEELP3ENSG00000134014.12chr8+2801731128017502280160842801615028017745280179730.124000.000000.00012includedK562RBM15
SEELP3ENSG00000134014.12chr8+2801731128017502280160842801615028017745280179730.138000.000000.00017includedK562AGGF1
SEELP3ENSG00000134014.12chr8+2804071028040781280195132801959528047165280476040.067000.000060.00692includedHepG2SRSF9
SEELP3ENSG00000134014.12chr8+279547352795483527950618279507502795734427957483-0.113000.001660.05931excludedK562PTBP1
A3SSELP3ENSG00000134014.12chr8+279547352795483527954745279548352795061827950750-0.077000.002050.09049shorterK562SF3B4
MXEELP3ENSG00000134014.12chr8+2795473527954835279573442795748327950628279507502796422927964300-0.144000.001770.046252includedHepG2MATR3
MXEELP3ENSG00000134014.12chr8+27967886279679552797053527970690279642292796430027987018279871800.136000.000010.000151includedK562AQR
MXEELP3ENSG00000134014.12chr8+2795473527954835279573442795756927950628279507502796422927964300-0.127000.002080.017212includedK562AQR
MXEELP3ENSG00000134014.12chr8+2795473527954835279573442795748327950628279507502796422927964300-0.147000.005740.061132includedK562U2AF2
MXEELP3ENSG00000134014.12chr8+27987018279871802798979427989921279705352797069027995214279954080.110000.016340.079771includedHepG2U2AF2
MXEELP3ENSG00000134014.12chr8+2795734427957483279642292796430027954735279548352796788627967955-0.308000.003790.024202includedHepG2U2AF2
MXEELP3ENSG00000134014.12chr8+2795473527954835279573442795748327950628279507502796422927964300-0.139000.001410.068062includedHepG2DDX3X
MXEELP3ENSG00000134014.12chr8+2795473527954835279573442795748327950628279507502796422927964300-0.174000.002110.034252includedK562SF3B4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ELP3 is not avaliable on ENCORE database.