EIF2B1

General Information

Gene Name : EIF2B1
Gene ID : ENSG00000111361.12
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: EIF2B1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	EIF2B1	ENSG00000111361.12	47.62	44.73	46.17	ENCSR000AEF
HepG2	EIF2B1	ENSG00000111361.12	29.60	34.30	31.95	ENCSR985KAT
K562	EIF2B1	ENSG00000111361.12	71.79	78.40	75.09	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for EIF2B1 is not avaliable on ENCORE database.

Proteins bound to RNA

EIF2B1 RNA is bound by 14 proteins.

eCLIP assay for EIF2B1 is not avaliable on ENCORE database.

14 proteins are bound to EIF2B1 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr12	124111001	124111088	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.32648	10.44734	K562	SF3B4
chr12	124110930	124110946	-	3'-UTR,intron-Distal,intron-Proximal	5.25389	7.28294	K562	AQR
chr12	124109315	124109401	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.54751	5.42118	K562	GRWD1
chr12	124107175	124107187	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.41962	3.85435	K562	PRPF8
chr12	124105615	124105720	-	3'-UTR,intron-Distal	4.91173	4.67790	K562	CPSF6
chr12	124106321	124106365	-	3'-UTR,CDS,intron-Distal	3.86437	3.05875	K562	RBM15
chr12	124110992	124111094	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.55722	5.47493	HepG2	BUD13
chr12	124106291	124106318	-	3'-UTR,CDS,intron-Distal	3.68215	5.37252	K562	YBX3
chr12	124111004	124111064	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.90111	12.35151	K562	AQR
chr12	124105692	124105751	-	3'-UTR,intron-Distal	3.04223	3.29251	K562	KHSRP
chr12	124110974	124111088	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.79527	6.03362	HepG2	AQR
chr12	124106247	124106291	-	3'-UTR,intron-Distal,intron-Proximal	3.44198	4.74241	K562	YBX3
chr12	124110946	124110972	-	3'-UTR,intron-Distal,intron-Proximal	4.03111	7.79506	K562	AQR
chr12	124107262	124107325	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.49727	3.02321	K562	U2AF2
chr12	124118091	124118219	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.41246	12.61629	K562	DDX3X
chr12	124116890	124116987	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.70587	6.98305	HepG2	PPIG
chr12	124111650	124111703	-	CDS,intron-Distal	3.69874	5.57640	K562	YBX3
chr12	124111549	124111624	-	CDS,intron-Distal,intron-Proximal	4.55380	29.23863	K562	PRPF8
chr12	124114950	124115004	-	CDS,intron-Distal	3.21249	7.42778	K562	YBX3
chr12	124111562	124111618	-	CDS,intron-Distal,intron-Proximal	3.26718	3.05161	HepG2	PPIG
chr12	124111482	124111638	-	CDS,intron-Distal,intron-Proximal	3.35393	14.03313	K562	BUD13
chr12	124111551	124111555	-	CDS,intron-Distal,intron-Proximal	5.23757	34.34521	K562	AQR
chr12	124111547	124111551	-	CDS,intron-Distal,intron-Proximal	4.30045	12.60688	K562	AQR
chr12	124116890	124116963	-	CDS,intron-Distal,intron-Proximal	3.10563	3.60157	HepG2	GRWD1
chr12	124111547	124111679	-	CDS,intron-Distal,intron-Proximal	6.22712	18.12830	HepG2	PRPF8
chr12	124116885	124116951	-	CDS,intron-Distal,intron-Proximal	3.09479	4.37507	K562	DDX24
chr12	124115004	124115052	-	CDS,intron-Distal	4.97751	16.47345	K562	YBX3
chr12	124111584	124111591	-	CDS,intron-Distal,intron-Proximal	4.64419	31.58001	K562	AQR
chr12	124111555	124111584	-	CDS,intron-Distal,intron-Proximal	5.07171	35.75572	K562	AQR
chr12	124109045	124109104	-	intron-Distal	3.81579	3.31709	K562	ILF3
chr12	124107138	124107175	-	intron-Distal,intron-Proximal	3.72346	3.20886	K562	PRPF8
chr12	124109285	124109332	-	intron-Distal,intron-Proximal	3.59644	3.88924	K562	PRPF8
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for EIF2B1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for EIF2B1 is not available on ENCORE database.
56 RBPs can affect the levels of EIF2B1.

The Knockdown/knockout RNA-Seq assay for EIF2B1 is not available on ENCORE database.

56 RBPs can affect the gene expression of EIF2B1 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
EIF2B1	ENSG00000111361.8	621.16630	475.69630	0.38480	2.38010	1.38270	HepG2	AATF
EIF2B1	ENSG00000111361.8	605.81870	815.34860	-0.42850	2.36370	1.86750	HepG2	AKAP1
EIF2B1	ENSG00000111361.8	854.95300	640.94150	0.41560	2.78790	2.01250	HepG2	CIRBP
EIF2B1	ENSG00000111361.8	436.42930	673.55380	-0.62600	5.06930	4.16310	HepG2	CPSF6
EIF2B1	ENSG00000111361.8	368.24710	524.64550	-0.51070	3.50110	2.74590	HepG2	DDX21
EIF2B1	ENSG00000111361.8	404.95910	670.96110	-0.72850	5.49680	4.65160	HepG2	DDX6
EIF2B1	ENSG00000111361.8	337.98390	480.00630	-0.50610	4.04830	3.21080	HepG2	DNAJC21
EIF2B1	ENSG00000111361.8	436.28810	644.96490	-0.56390	3.89470	3.19840	HepG2	EIF2S1
EIF2B1	ENSG00000111361.8	538.02440	763.54960	-0.50510	3.22920	2.54240	HepG2	GPKOW
EIF2B1	ENSG00000111361.8	698.48690	836.76660	-0.26060	2.10630	1.47430	HepG2	HNRNPF
EIF2B1	ENSG00000111361.8	569.07280	728.66730	-0.35660	1.96940	1.43030	HepG2	HNRNPLL
EIF2B1	ENSG00000111361.8	684.37270	535.45490	0.35390	3.09930	2.46000	HepG2	HNRNPU
EIF2B1	ENSG00000111361.8	523.11640	743.09360	-0.50640	2.64840	1.70320	HepG2	MTPAP
EIF2B1	ENSG00000111361.8	722.16430	973.39240	-0.43070	3.93300	3.13680	HepG2	PUM2
EIF2B1	ENSG00000111361.8	836.64220	579.65300	0.52930	2.32810	1.67750	HepG2	RAVER1
EIF2B1	ENSG00000111361.8	521.71350	700.84320	-0.42580	3.24610	2.52150	HepG2	RBM25
EIF2B1	ENSG00000111361.8	682.35000	879.91220	-0.36680	3.85700	3.04970	HepG2	SLBP
EIF2B1	ENSG00000111361.8	348.02110	590.89010	-0.76370	5.36410	4.00160	HepG2	SMNDC1
EIF2B1	ENSG00000111361.8	523.53200	802.51270	-0.61620	3.42440	2.55020	HepG2	SNRNP70
EIF2B1	ENSG00000111361.8	739.17410	906.04930	-0.29370	2.46690	1.87140	HepG2	SRSF5
EIF2B1	ENSG00000111361.8	322.96770	616.36210	-0.93240	7.10020	6.09670	HepG2	SUPV3L1
EIF2B1	ENSG00000111361.8	483.00200	364.13520	0.40750	2.44100	1.72800	HepG2	UCHL5
EIF2B1	ENSG00000111361.8	413.70440	576.20140	-0.47800	4.72030	3.88160	HepG2	ZC3H8
EIF2B1	ENSG00000111361.8	1106.21490	669.36210	0.72470	16.37340	15.32100	HepG2	ZNF622
EIF2B1	ENSG00000111361.8	1678.44650	1343.61020	0.32090	2.66290	1.50670	K562	AARS
EIF2B1	ENSG00000111361.8	1316.77450	1682.77590	-0.35380	5.27860	3.93540	K562	BCLAF1
EIF2B1	ENSG00000111361.8	1401.61060	1809.49900	-0.36850	2.46820	1.64720	K562	BOP1
EIF2B1	ENSG00000111361.8	1638.65960	2120.19800	-0.37170	2.83070	1.39520	K562	BUD13
EIF2B1	ENSG00000111361.8	1459.46820	1924.10860	-0.39870	2.56750	1.81100	K562	CPSF6
EIF2B1	ENSG00000111361.8	755.31780	958.00580	-0.34300	2.75290	1.71360	K562	DDX3X
EIF2B1	ENSG00000111361.8	3316.23000	2379.09020	0.47900	5.74950	4.86120	K562	DDX47
EIF2B1	ENSG00000111361.8	1943.15540	2688.45870	-0.46840	4.83340	3.91830	K562	EIF2S2
EIF2B1	ENSG00000111361.8	1758.35770	1134.50550	0.63210	11.57160	9.92420	K562	EIF3G
EIF2B1	ENSG00000111361.8	932.86290	1213.72640	-0.37970	3.31020	1.54400	K562	FASTKD2
EIF2B1	ENSG00000111361.8	2058.01930	1040.83710	0.98340	29.33120	27.49330	K562	FXR1
EIF2B1	ENSG00000111361.8	1446.72280	1837.12380	-0.34470	2.08480	1.39190	K562	GPKOW
EIF2B1	ENSG00000111361.8	1051.09610	1470.20400	-0.48410	5.34890	4.54390	K562	HNRNPC
EIF2B1	ENSG00000111361.8	1570.62610	1214.79240	0.37050	2.70170	1.48740	K562	HNRNPK
EIF2B1	ENSG00000111361.8	2368.56200	2966.59480	-0.32480	2.60770	1.83380	K562	HSPD1
EIF2B1	ENSG00000111361.8	1357.04590	1793.20680	-0.40210	2.32480	1.52490	K562	METAP2
EIF2B1	ENSG00000111361.8	1512.41300	1137.34280	0.41110	3.84770	2.69120	K562	PCBP2
EIF2B1	ENSG00000111361.8	1910.36920	1410.86470	0.43720	4.17540	3.25450	K562	PRPF8
EIF2B1	ENSG00000111361.8	981.31560	1318.18890	-0.42580	3.60400	2.55300	K562	PSIP1
EIF2B1	ENSG00000111361.8	1624.18200	1241.86110	0.38710	4.10660	3.31330	K562	PTBP1
EIF2B1	ENSG00000111361.8	4289.25130	3515.45930	0.28690	2.20670	1.47910	K562	PUF60
EIF2B1	ENSG00000111361.8	1633.37470	1351.05640	0.27370	1.84410	1.38260	K562	PUS1
EIF2B1	ENSG00000111361.8	1799.72660	1437.22950	0.32440	2.19270	1.46920	K562	RPS19
EIF2B1	ENSG00000111361.8	1217.02720	934.09060	0.38160	2.52380	1.57380	K562	RPS3
EIF2B1	ENSG00000111361.8	1738.53660	1429.23270	0.28250	2.27720	1.30260	K562	SAFB
EIF2B1	ENSG00000111361.8	1292.37290	991.00930	0.38300	3.85790	2.84340	K562	SF3B4
EIF2B1	ENSG00000111361.8	895.14580	1140.09290	-0.34900	2.56790	1.59050	K562	SRFBP1
EIF2B1	ENSG00000111361.8	946.52050	1170.26810	-0.30610	2.75250	1.48060	K562	SSB
EIF2B1	ENSG00000111361.8	869.36470	1366.20960	-0.65210	6.17860	4.61650	K562	SUPV3L1
EIF2B1	ENSG00000111361.8	2233.91800	1608.91230	0.47340	6.70740	5.41790	K562	SYNCRIP
EIF2B1	ENSG00000111361.8	1922.60760	2560.10380	-0.41310	3.40620	1.84010	K562	TRIP6
EIF2B1	ENSG00000111361.8	1989.34070	2529.78320	-0.34670	5.62900	3.78900	K562	TROVE2
EIF2B1	ENSG00000111361.8	1044.35050	1445.87070	-0.46930	3.96980	2.72700	K562	UCHL5
EIF2B1	ENSG00000111361.8	1456.78190	1843.42290	-0.33960	3.33180	2.37610	K562	WDR3
EIF2B1	ENSG00000111361.8	2259.09050	1916.86460	0.23690	3.17510	2.27330	K562	WDR43
EIF2B1	ENSG00000111361.8	1976.45730	1162.14400	0.76600	4.39850	2.25820	K562	XRCC6
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for EIF2B1 is not available on ENCORE database.

14 RBPs can affect the splicing of EIF2B1 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124109333	124109470			124109333	124109409	124110971	124111040	0.23100	0.00002	0.00412	longer	K562	AGGF1
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124109333	124109470			124109333	124109409	124110971	124111040	0.20800	0.00038	0.03759	longer	K562	AKAP8L
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124109333	124109470			124109333	124109409	124110971	124111040	0.21100	0.00001	0.00924	longer	K562	PPIL4
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124109333	124109470			124109333	124109409	124110971	124111040	0.44400	0.00000	0.00000	longer	K562	U2AF2
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124109333	124109470			124109333	124109409	124110971	124111040	-0.17900	0.00000	0.00001	shorter	K562	FXR1
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124109333	124109470			124109333	124109409	124110971	124111040	0.26900	0.00015	0.00542	longer	HepG2	U2AF2
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124106284	124106517			124106284	124106467	124107182	124107339	0.06600	0.00001	0.00009	longer	K562	AQR
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124109333	124109493			124109333	124109409	124110971	124111040	0.24900	0.00000	0.00000	longer	K562	AQR
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124107182	124107350			124107182	124107308	124109333	124109409	0.07800	0.00001	0.00014	longer	K562	AQR
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124111590	124111719			124111590	124111703	124114715	124114832	0.08000	0.00000	0.00000	longer	K562	AQR
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124110971	124111104			124110971	124111040	124111590	124111719	0.12900	0.00000	0.00001	longer	K562	AQR
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124114654	124114851			124114654	124114832	124114943	124115139	0.31400	0.00000	0.00000	longer	K562	AQR
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124116891	124117037			124116891	124116993	124118091	124118313	0.12000	0.00000	0.00000	longer	K562	AQR
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124109333	124109470			124109333	124109409	124110971	124111040	0.18500	0.00024	0.01508	longer	K562	PUS1
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124109333	124109470			124109333	124109409	124110971	124111040	0.20100	0.00009	0.07524	longer	K562	LARP4
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124109333	124109470			124109333	124109409	124110971	124111040	-0.18300	0.00029	0.05388	shorter	HepG2	SFPQ
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124109333	124109470			124109333	124109409	124110971	124111040	0.18400	0.00113	0.04441	longer	HepG2	U2AF1
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124109333	124109470			124109333	124109409	124110971	124111040	0.19500	0.00065	0.03138	longer	K562	U2AF1
A3SS	EIF2B1	ENSG00000111361.8	chr12	-	124109333	124109470			124109333	124109409	124110971	124111040	0.15800	0.00007	0.07541	longer	K562	DDX55
A5SS	EIF2B1	ENSG00000111361.8	chr12	-	124111463	124111703			124111590	124111703	124110971	124111040	0.07100	0.00074	0.06188	longer	K562	RBM15
MXE	EIF2B1	ENSG00000111361.8	chr12	-	124109333	124109409	124110971	124111040	124107182	124107308	124111590	124111703	0.13300	0.00002	0.00112	1included	K562	DROSHA
MXE	EIF2B1	ENSG00000111361.8	chr12	-	124109333	124109409	124110971	124111040	124107182	124107308	124111590	124111703	0.11200	0.00085	0.02135	1included	K562	HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

EIF2B1

General Information

Functions

Localization

Domains (AlphaFold: EIF2B1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for EIF2B1 is not avaliable on ENCORE database.

14 proteins are bound to EIF2B1 RNA:

eCLIP assay for EIF2B1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for EIF2B1 is not available on ENCORE database.

56 RBPs can affect the gene expression of EIF2B1 :

The Knockdown/knockout RNA-Seq assay for EIF2B1 is not available on ENCORE database.

14 RBPs can affect the splicing of EIF2B1 :

The Knockdown/knockout RNA-Seq assay for EIF2B1 is not avaliable on ENCORE database.