DOCK1

General Information

Gene Name       : DOCK1
Gene ID             : ENSG00000150760.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DOCK1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DOCK1ENSG00000150760.120.000.000.00ENCSR000AEF
HepG2DOCK1ENSG00000150760.1216.6017.8917.25ENCSR985KAT
K562DOCK1ENSG00000150760.120.000.000.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DOCK1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • DOCK1 RNA is bound by 34 proteins.  







eCLIP assay for DOCK1 is not avaliable on ENCORE database.





34 proteins are bound to DOCK1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr10128594039128594116+5'-UTR,CDS3.020695.26571HepG2NCBP2
chr10128816987128817079+CDS4.0037817.19016HepG2BCLAF1
chr10128788786128788835+CDS3.194754.24005HepG2BCLAF1
chr10128830417128830500+CDS3.0673410.00803HepG2BCLAF1
chr10128807052128807069+CDS,intron-Proximal5.224296.24363HepG2EIF3H
chr10129183102129183174+CDS,intron-Proximal4.084923.93054HepG2LIN28B
chr10128796460128796506+CDS4.832065.52963HepG2PPIG
chr10128821512128821584+CDS4.527155.48415HepG2EIF3H
chr10128798497128798524+CDS3.206114.56058HepG2BCLAF1
chr10128810557128810602+CDS,intron-Proximal5.480007.72559HepG2EIF3H
chr10128830438128830529+CDS3.998567.03378HepG2GRWD1
chr10129160349129160413+CDS4.473354.56100HepG2FXR2
chr10128797680128797737+CDS,intron-Proximal6.119539.06713HepG2PRPF8
chr10128810556128810594+CDS,intron-Proximal3.123683.78006HepG2PPIG
chr10128859956128860015+CDS3.346004.71371HepG2GRWD1
chr10129213475129213544+CDS,intron-Proximal4.857948.77485HepG2PRPF8
chr10129046340129046368+CDS3.623684.13746HepG2PPIG
chr10129201327129201353+CDS4.665304.78529HepG2BCLAF1
chr10128817034128817093+CDS3.304754.78418HepG2EIF3H
chr10129160447129160474+CDS3.259394.26492HepG2BCLAF1
chr10128821560128821588+CDS3.503087.42278HepG2BCLAF1
chr10128822948128822997+CDS,intron-Proximal3.351314.00333HepG2EIF3H
chr10128904519128904557+CDS3.176534.51003HepG2PPIG
chr10128797618128797640+CDS4.150847.09561HepG2BCLAF1
chr10128796411128796505+CDS3.467754.21853HepG2EIF3D
chr10128840886128840943+CDS,intron-Proximal3.286493.94960HepG2EIF3H
chr10128840889128840937+CDS3.144953.40321HepG2GRWD1
chr10128822948128823039+CDS,intron-Proximal5.0835520.06099HepG2BCLAF1
chr10128821509128821560+CDS3.711728.25092HepG2BCLAF1
chr10128796447128796513+CDS3.8897910.98590HepG2BCLAF1
chr10128806995128807065+CDS,intron-Proximal4.3080014.24397HepG2BCLAF1
chr10128807033128807070+CDS,intron-Proximal3.073674.05271HepG2PPIG
chr10128796439128796511+CDS3.784405.52031HepG2GRWD1
chr10128810558128810601+CDS,intron-Proximal3.002707.90382HepG2BCLAF1
chr10128829949128830003+CDS3.479405.79905HepG2BCLAF1
chr10128798555128798571+CDS3.996785.35703HepG2BCLAF1
chr10128594701128594756+intron-Distal3.149874.98353HepG2CSTF2T
chr10128994217128994260+intron-Distal3.721593.16310HepG2CSTF2T
chr10128594162128594257+intron-Distal,intron-Proximal3.383678.62898HepG2CSTF2T
chr10128609364128609410+intron-Distal4.3780216.18886HepG2TROVE2
chr10128816379128816433+intron-Distal5.433395.39754HepG2HNRNPL
chr10129161249129161428+intron-Distal5.7527410.30844HepG2XPO5
chr10128609378128609414+intron-Distal4.5192645.68683K562TROVE2
chr10128599896128599972+intron-Distal4.9262920.86201HepG2HNRNPM
chr10128773511128773572+intron-Distal3.392574.08528HepG2SUGP2
chr10129209362129209424+intron-Distal3.023063.06005HepG2QKI
chr10129060025129060091+intron-Distal5.408877.70656HepG2DKC1
chr10128773487128773565+intron-Distal3.764103.84494HepG2QKI
chr10128813089128813158+intron-Distal4.770053.04956HepG2HNRNPL
chr10128815837128815901+intron-Distal4.8350413.53830HepG2AGGF1
chr10129119510129119635+intron-Distal5.265156.79054HepG2PCBP2
chr10128815851128815897+intron-Distal4.6016812.85441HepG2HNRNPL
chr10128609362128609373+intron-Distal7.3489040.64100K562TROVE2
chr10129161264129161374+intron-Distal5.6556210.65264HepG2AGGF1
chr10128594263128594316+intron-Distal3.049164.07062HepG2CSTF2T
chr10129080473129080563+intron-Distal4.7086212.24240HepG2PTBP1
chr10128600130128600189+intron-Distal4.166783.79821HepG2BCCIP
chr10128594666128594714+intron-Distal4.382583.82670HepG2SFPQ
chr10128814690128814736+intron-Distal4.056584.59145HepG2XPO5
chr10129161103129161264+intron-Distal5.666007.76403HepG2AGGF1
chr10129117677129117736+intron-Distal4.220384.24431HepG2RBFOX2
chr10128815927128816034+intron-Distal4.951575.27767HepG2GTF2F1
chr10128970618128970695+intron-Distal4.572798.18285HepG2XPO5
chr10128775556128775632+intron-Distal4.306914.53347HepG2SUGP2
chr10128940662128940722+intron-Distal4.352893.86368HepG2HNRNPM
chr10128772909128772956+intron-Distal3.809023.39864HepG2SUGP2
chr10129060091129060139+intron-Distal4.896405.95110HepG2DKC1
chr10128594894128594967+intron-Distal3.727654.95619HepG2SFPQ
chr10128813157128813266+intron-Distal3.498783.76399HepG2CDC40
chr10128613005128613093+intron-Distal3.715934.18895HepG2FKBP4
chr10128813171128813249+intron-Distal5.468826.94016HepG2AGGF1
chr10129146129129146226+intron-Distal5.520848.60492HepG2PCBP2
chr10128605204128605358+intron-Distal6.9569728.98949HepG2PCBP2
chr10128615822128615886+intron-Distal4.093613.62366HepG2HNRNPM
chr10129059508129059575+intron-Distal4.619574.17531HepG2RBFOX2
chr10128600012128600051+intron-Distal3.030845.08467HepG2HNRNPM
chr10128775469128775545+intron-Distal3.643374.86210HepG2HNRNPM
chr10128613007128613129+intron-Distal3.405055.47992HepG2HNRNPUL1
chr10128594572128594625+intron-Distal3.997566.85787HepG2CSTF2T
chr10128940698128940762+intron-Distal3.290863.46325HepG2SUGP2
chr10128781651128781825+intron-Distal3.925555.07626HepG2PTBP1
chr10128605223128605356+intron-Distal5.6628825.93372HepG2PTBP1
chr10129161261129161374+intron-Distal4.840707.68255HepG2HNRNPL
chr10128594789128594894+intron-Distal4.153527.38964HepG2SFPQ
chr10128605218128605348+intron-Distal3.178254.53157HepG2MATR3
chr10128815943128816017+intron-Distal3.783944.57703HepG2CDC40
chr10128599626128599654+intron-Distal3.535513.68481HepG2HNRNPM
chr10129060030129060123+intron-Distal5.073015.52571HepG2RBFOX2
chr10128994164128994197+intron-Distal3.799603.40229HepG2CSTF2T
chr10128599842128599896+intron-Distal5.3928517.99708HepG2HNRNPM
chr10128774080128774142+intron-Distal3.212093.46325HepG2SUGP2
chr10128815915128815962+intron-Distal6.0493811.41498HepG2HNRNPL
chr10129034593129034700+intron-Distal4.9138914.08485HepG2PCBP2
chr10128791071128791130+intron-Distal3.492704.14321HepG2HNRNPL
chr10128826248128826376+intron-Distal3.326143.98726HepG2RBFOX2
chr10128608284128608379+intron-Distal6.8602518.97615HepG2XPO5
chr10128814649128814727+intron-Distal4.170443.86455HepG2GTF2F1
chr10128813778128813810+intron-Distal4.884686.18180HepG2AGGF1
chr10128772758128772806+intron-Distal3.242793.69184HepG2SUGP2
chr10128594840128594933+intron-Distal4.176263.19863HepG2EIF3D
chr10128609373128609378+intron-Distal4.5277743.98030K562TROVE2
chr10128814827128814910+intron-Distal6.2558118.75818HepG2AGGF1
chr10128816380128816426+intron-Distal5.469845.95153HepG2AGGF1
chr10128982679128982782+intron-Distal3.743833.06084HepG2HNRNPK
chr10128608584128608652+intron-Distal3.799603.40229HepG2CSTF2T
chr10128815924128816032+intron-Distal7.5880944.50679HepG2AGGF1
chr10128854828128854931+intron-Distal5.157888.48075HepG2PTBP1
chr10128599784128599842+intron-Distal5.5936112.23409HepG2HNRNPM
chr10128782128128782228+intron-Distal3.370803.35585HepG2QKI
chr10129068789129068864+intron-Distal4.967355.36996HepG2PCBP2
chr10128598498128598568+intron-Distal4.151343.97018HepG2HNRNPM
chr10128815933128816033+intron-Distal6.6165215.64735HepG2XPO5
chr10128594878128594899+intron-Distal3.221593.72734HepG2CSTF2T
chr10128851155128851288+intron-Distal,intron-Proximal4.6231113.35401HepG2U2AF2
chr10128594365128594451+intron-Distal5.285186.92491HepG2FAM120A
chr10128815725128815837+intron-Distal4.4178020.76879HepG2AGGF1
chr10128993881128993937+intron-Distal3.073873.49516HepG2CSTF2T
chr10128813160128813267+intron-Distal3.780734.61722HepG2HNRNPL
chr10128613966128614022+intron-Distal4.413984.45335HepG2HNRNPC
chr10128612990128613112+intron-Distal5.9005716.50696HepG2RBFOX2
chr10128781774128781944+intron-Distal5.7692410.42241HepG2RBFOX2
chr10128605038128605078+intron-Distal4.189933.62366HepG2HNRNPM
chr10128814633128814752+intron-Distal5.1951811.87188HepG2HNRNPL
chr10128614439128614528+intron-Distal3.372304.25221HepG2LSM11
chr10128814647128814727+intron-Distal5.1711412.08621HepG2AGGF1
chr10128815962128816038+intron-Distal6.1640026.83878HepG2HNRNPL
chr10128810472128810543+intron-Proximal3.128263.37120HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DOCK1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DOCK1 is not available on ENCORE database.

  • 55 RBPs can affect the levels of DOCK1.  








The Knockdown/knockout RNA-Seq assay for DOCK1 is not available on ENCORE database.





55 RBPs can affect the gene expression of DOCK1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DOCK1ENSG00000150760.81695.834901271.631900.415203.913502.65530HepG2AATF
DOCK1ENSG00000150760.82505.974601714.059200.547904.811704.13590HepG2AKAP1
DOCK1ENSG00000150760.81788.634201461.356900.291403.630902.76520HepG2AKAP8L
DOCK1ENSG00000150760.81951.465001418.272000.460304.078803.13320HepG2ASCC1
DOCK1ENSG00000150760.8770.002601562.21770-1.0207018.2118016.87730HepG2BOP1
DOCK1ENSG00000150760.81757.573701492.971300.235301.973901.31380HepG2CALR
DOCK1ENSG00000150760.81835.924701434.222900.356102.935902.23030HepG2CPSF6
DOCK1ENSG00000150760.8971.585901218.92210-0.327203.230602.12810HepG2YBX3
DOCK1ENSG00000150760.81356.966301823.48040-0.426308.568107.37350HepG2DAZAP1
DOCK1ENSG00000150760.81876.421901410.357300.411802.908402.27670HepG2DDX6
DOCK1ENSG00000150760.81467.808401196.872100.294303.048902.31520HepG2DNAJC21
DOCK1ENSG00000150760.82814.062001458.934400.9476010.582909.27910HepG2EIF4B
DOCK1ENSG00000150760.81472.633201798.96240-0.288803.443102.52570HepG2EIF4G1
DOCK1ENSG00000150760.83241.565902446.608700.405808.059207.12560HepG2ETF1
DOCK1ENSG00000150760.82010.775301421.334100.500406.442805.17020HepG2EWSR1
DOCK1ENSG00000150760.8888.576801093.41070-0.299302.455101.35790HepG2FAM120A
DOCK1ENSG00000150760.82460.707701862.212000.402002.756901.98850HepG2FIP1L1
DOCK1ENSG00000150760.81353.189601066.518900.343402.906102.10150HepG2FUBP3
DOCK1ENSG00000150760.81972.000801511.774700.383303.019302.29550HepG2FXR1
DOCK1ENSG00000150760.81745.320501402.515800.315401.988701.42060HepG2G3BP1
DOCK1ENSG00000150760.81484.349201208.338800.296702.136101.56140HepG2HNRNPA1
DOCK1ENSG00000150760.81853.582701344.062200.463604.900503.99740HepG2HNRNPC
DOCK1ENSG00000150760.81151.991601512.30140-0.392602.774702.11940HepG2MAGOH
DOCK1ENSG00000150760.8706.645101135.30630-0.684003.953602.87970HepG2PABPC1
DOCK1ENSG00000150760.81980.099901321.584200.5832012.6187011.02400HepG2PARN
DOCK1ENSG00000150760.81767.964101308.787800.433807.377506.46540HepG2PCBP1
DOCK1ENSG00000150760.81139.698101434.64530-0.332004.124703.20060HepG2PRPF4
DOCK1ENSG00000150760.81670.169801331.787700.326503.189402.61000HepG2PTBP1
DOCK1ENSG00000150760.82116.940601832.264200.208302.852402.25260HepG2PUM1
DOCK1ENSG00000150760.82129.438401530.597600.476302.319701.67060HepG2RAVER1
DOCK1ENSG00000150760.81561.884801906.34420-0.287502.541601.71670HepG2RBM15
DOCK1ENSG00000150760.82676.050402044.905300.388005.879105.19350HepG2RBM22
DOCK1ENSG00000150760.81003.034101381.89660-0.462303.540202.34030HepG2RCC2
DOCK1ENSG00000150760.81937.281801482.112700.386305.899005.15670HepG2NELFE
DOCK1ENSG00000150760.81955.225701380.457600.502109.799708.74730HepG2RECQL
DOCK1ENSG00000150760.8874.080801174.38410-0.426102.615101.34010HepG2SART3
DOCK1ENSG00000150760.81673.809001386.478300.271603.112802.49040HepG2SF3B4
DOCK1ENSG00000150760.81695.685001386.598500.290204.232903.46740HepG2SMN1
DOCK1ENSG00000150760.82026.837801447.217700.485809.830109.06210HepG2SRSF1
DOCK1ENSG00000150760.82129.745801704.208500.321504.650703.87480HepG2SRSF5
DOCK1ENSG00000150760.81678.634202005.28710-0.256503.307302.75800HepG2SSB
DOCK1ENSG00000150760.8672.478801084.76290-0.689805.654004.02930HepG2STIP1
DOCK1ENSG00000150760.82343.340401938.159700.273804.188103.45160HepG2SUCLG1
DOCK1ENSG00000150760.82433.244601300.911500.9033026.2021024.70650HepG2TAF15
DOCK1ENSG00000150760.81446.728901195.258800.275402.296801.53310HepG2TIA1
DOCK1ENSG00000150760.81768.685601297.339700.447005.791705.11890HepG2TIAL1
DOCK1ENSG00000150760.81516.120901308.972100.211902.112401.60740HepG2TRIM56
DOCK1ENSG00000150760.8962.490201592.90370-0.726809.428908.25710HepG2U2AF1
DOCK1ENSG00000150760.8925.405101712.12900-0.887602.597901.64320HepG2U2AF2
DOCK1ENSG00000150760.82468.959501784.875600.468003.946002.93680HepG2UBE2L3
DOCK1ENSG00000150760.8541.05010806.46040-0.575804.650403.66220HepG2UCHL5
DOCK1ENSG00000150760.8892.649001250.11010-0.485902.628401.65170HepG2UPF2
DOCK1ENSG00000150760.8712.327401117.03000-0.649104.740803.29020HepG2XPO5
DOCK1ENSG00000150760.8971.996501343.87130-0.467403.651502.82780HepG2XRN2
DOCK1ENSG00000150760.81330.178601795.47050-0.432709.140208.29300HepG2ZNF622
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DOCK1 is not available on ENCORE database.





2 RBPs can affect the splicing of DOCK1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSDOCK1ENSG00000150760.8chr10+1288104951288106381288105581288106381288069951288070680.370000.000000.00000longerHepG2U2AF2
A3SSDOCK1ENSG00000150760.8chr10+1288104951288106381288105581288106381288069951288070680.269000.000000.00000longerHepG2U2AF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DOCK1 is not avaliable on ENCORE database.