DCPS

General Information

Gene Name       : DCPS
Gene ID             : ENSG00000110063.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: DCPS)


Antibody Validation

 View validation images for all DCPS antibodies

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DCPSENSG00000110063.936.2452.6944.47ENCSR000AEF
HepG2DCPSENSG00000110063.930.1620.3825.27ENCSR985KAT
K562DCPSENSG00000110063.926.8825.6026.24ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq DCPS-BGKcLV28-K562ENCSR166VYIDCPSK562ReleasedENCSR220DTX   CRISPRKD% = 71.9,66.8
knockdown followed by RNA-seq DCPS-BGHcLV29-HepG2ENCSR524NOZDCPSHepG2ReleasedENCSR462MFN   CRISPRKD% = 70.8,71.4






  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
DCPSENCAB507CYAA305-426A1Released, ENCODE4BGKcLV28-63, Released, ENCODE4
DCPSENCAB554JMAA305-444A1Released, ENCODE4BGHcLV29-63, Released, ENCODE4


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
DCPSK562CRISPRENCSR166VYIENCSR220DTXDCPS-BGKcLV28-63,DCPS-BGKcLV28-64NT-BGKcLV28-1,NT-BGKcLV28-271.9,66.8ReleasedENCODE4
DCPSHepG2CRISPRENCSR524NOZENCSR462MFNDCPS-BGHcLV29-63,DCPS-BGHcLV29-64NT-BGHcLV29-1,NT-BGHcLV29-270.8,71.4ReleasedENCODE4


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
DCPSProduct_ID: A305-426A
Lot_ID: 1
Source: Bethyl Labs
Target Name: DCPS-human		 Bethyl_A305-426A_1_DCPS.png<br>Caption: IP-WB analysis of K562 whole cell lysate using the DCPS specific antibody, A305-426A. Lanes 1 and 2 are 2.5% of five million whole cell lysate input and 50% of IP enrichment, respectively, using a normal IgG antibody. Lane 3 is 50% of IP enrichment from five million whole cell lysate using the DCPS-specific antibody, A305-426A. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.
 DCPS-K562-CRISPR-A305-426A.png<br>Caption: Western blot following CRISPR against DCPS in K562 whole cell lysate using DCPS specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against DCPS. DCPS protein appears as the green arrow, Tubulin serves as a control and appears in red arrow.
DCPSProduct_ID: A305-444A
Lot_ID: 1
Source: Bethyl Labs
Target Name: DCPS-human		 DCPS-HEPG2-CRISPR-A305-444A.png<br>Caption: Western blot following CRISPR against DCPS in HepG2 whole cell lysate using DCPS specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against DCPS. DCPS protein appears as the green arrow, Tubulin serves as a control and appears in red arrow.
 Bethyl_A305-444A_1_DCPS.png<br>Caption: IP-WB analysis of K562 whole cell lysate using the DCPS specific antibody, A305-444A. Lanes 1 and 2 are 2.5% of five million whole cell lysate input and 50% of IP enrichment, respectively, using a normal IgG antibody. Lane 3 is 50% of IP enrichment from five million whole cell lysate using the DCPS-specific antibody, A305-444A. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.








RNA Targets

  • eCLIP assay for DCPS is not avaliable on ENCORE database.



Proteins bound to RNA
  • DCPS RNA is bound by 1 proteins.  







eCLIP assay for DCPS is not avaliable on ENCORE database.





1 proteins are bound to DCPS RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr11126173985126174069+CDS4.121144.26442K562DDX3X
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DCPS is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DCPS is not available on ENCORE database.

  • 67 RBPs can affect the levels of DCPS.  








The Knockdown/knockout RNA-Seq assay for DCPS is not available on ENCORE database.





67 RBPs can affect the gene expression of DCPS :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DCPSENSG00000110063.4526.10420271.315700.955307.219406.40450HepG2AKAP1
DCPSENSG00000110063.4166.59080280.54520-0.751904.292703.56610HepG2BOP1
DCPSENSG00000110063.4158.48410280.33620-0.822805.285604.26200HepG2CALR
DCPSENSG00000110063.4145.16890257.55630-0.827204.423803.57120HepG2CPSF6
DCPSENSG00000110063.4161.04720254.16860-0.658303.173402.35350HepG2DDX55
DCPSENSG00000110063.4210.25370336.31850-0.677704.126103.14190HepG2EIF4G2
DCPSENSG00000110063.4331.41920470.56190-0.505704.229003.51350HepG2ETF1
DCPSENSG00000110063.4132.56870257.99660-0.960602.949001.89880HepG2FTO
DCPSENSG00000110063.4359.21800239.330800.585803.049002.32270HepG2FXR1
DCPSENSG00000110063.4180.79800291.96150-0.691403.374402.67200HepG2GPKOW
DCPSENSG00000110063.4307.80960395.31200-0.361002.178101.53650HepG2HNRNPF
DCPSENSG00000110063.4319.65600224.847900.507502.346901.70140HepG2HNRNPK
DCPSENSG00000110063.4146.32620278.62410-0.929105.526104.66840HepG2HNRNPLL
DCPSENSG00000110063.4286.44910389.27020-0.442502.637901.93010HepG2IGF2BP1
DCPSENSG00000110063.4199.78360271.80870-0.444202.480401.78250HepG2ILF2
DCPSENSG00000110063.4192.93520291.73430-0.596503.317302.43470HepG2MSI2
DCPSENSG00000110063.4181.71380284.15730-0.645002.182501.32940HepG2MTPAP
DCPSENSG00000110063.4128.08660247.05250-0.947705.206704.19450HepG2NSUN2
DCPSENSG00000110063.4335.24090250.509200.420202.458701.87900HepG2PCBP1
DCPSENSG00000110063.4108.00860195.96250-0.859404.145303.17970HepG2PRPF8
DCPSENSG00000110063.4190.72570336.85450-0.820605.893005.06740HepG2PUF60
DCPSENSG00000110063.4197.28720393.30290-0.995309.407208.58000HepG2RBM22
DCPSENSG00000110063.4243.29470425.83700-0.807606.377205.40080HepG2RPLP0
DCPSENSG00000110063.4133.83130193.83690-0.534401.989501.31190HepG2RRP9
DCPSENSG00000110063.4113.17080306.85740-1.439109.059507.65170HepG2SNRNP70
DCPSENSG00000110063.4325.83260444.22160-0.447103.422602.88330HepG2SRFBP1
DCPSENSG00000110063.4406.04450277.005400.551604.106103.55790HepG2SRSF1
DCPSENSG00000110063.4279.01650388.37850-0.477103.293802.54340HepG2SRSF7
DCPSENSG00000110063.4163.23880225.36390-0.465302.191101.68830HepG2SRSF9
DCPSENSG00000110063.4233.29790385.69030-0.725306.564805.83820HepG2SSB
DCPSENSG00000110063.4116.82200252.98960-1.114806.889005.89850HepG2SUPV3L1
DCPSENSG00000110063.4144.46080271.56850-0.910605.517904.54740HepG2TARDBP
DCPSENSG00000110063.4178.11860258.52730-0.537502.679502.18560HepG2TIAL1
DCPSENSG00000110063.4180.26320260.87770-0.533302.975602.39570HepG2TRIM56
DCPSENSG00000110063.4189.47840308.38770-0.702704.019703.26860HepG2U2AF1
DCPSENSG00000110063.4231.92440348.33750-0.586802.486301.69590HepG2UBE2L3
DCPSENSG00000110063.490.67560149.42730-0.720702.977502.19290HepG2UCHL5
DCPSENSG00000110063.4339.44780237.816500.513203.268602.62740HepG2UTP3
DCPSENSG00000110063.4158.00160259.62220-0.716504.784403.94150HepG2ZC3H8
DCPSENSG00000110063.4686.68750551.354800.316601.854501.31510K562AKAP8L
DCPSENSG00000110063.4744.39510549.981300.436603.215601.87860K562APOBEC3C
DCPSENSG00000110063.4281.90690457.65580-0.699004.701003.97300K562AQR
DCPSENSG00000110063.4570.49740766.26860-0.425603.139702.10270K562CELF1
DCPSENSG00000110063.4917.97160501.754500.8714016.6038015.12810K562DDX47
DCPSENSG00000110063.4769.83830593.320700.375603.308702.34130K562DKC1
DCPSENSG00000110063.4161.13750255.27670-0.663803.384201.88990K562DNAJC21
DCPSENSG00000110063.4230.42070368.94010-0.679103.499501.63120K562ESF1
DCPSENSG00000110063.4177.04290269.09460-0.604002.951902.06760K562FMR1
DCPSENSG00000110063.4134.65810228.07360-0.760203.730202.65560K562FTO
DCPSENSG00000110063.4370.66450252.623000.553003.732403.04500K562FXR1
DCPSENSG00000110063.479.54660176.56660-1.150305.589704.50380K562G3BP2
DCPSENSG00000110063.4167.85290252.53210-0.589302.761801.96800K562GPKOW
DCPSENSG00000110063.4193.80730345.38630-0.833605.915405.07460K562HNRNPC
DCPSENSG00000110063.4466.80400285.402400.709704.794303.53430K562HNRNPM
DCPSENSG00000110063.4302.95100399.49280-0.399102.357001.53170K562HNRNPU
DCPSENSG00000110063.4705.17040470.465100.583804.740503.70650K562HSPD1
DCPSENSG00000110063.4130.08720215.61020-0.728902.834201.88690K562KRR1
DCPSENSG00000110063.4728.38300560.110800.378902.289901.34140K562MAK16
DCPSENSG00000110063.4143.82530246.49620-0.777204.409203.28580K562METAP2
DCPSENSG00000110063.4391.91470664.36550-0.761406.978205.21520K562MSI2
DCPSENSG00000110063.4267.36580366.09960-0.453402.088101.38050K562MTPAP
DCPSENSG00000110063.4604.91910326.683900.888704.023902.77370K562PABPN1
DCPSENSG00000110063.4259.84860395.67620-0.606603.512302.57490K562PCBP3
DCPSENSG00000110063.4219.38900303.49650-0.468202.433701.68510K562POLR2G
DCPSENSG00000110063.4369.60870239.006200.628904.621703.78460K562PTBP1
DCPSENSG00000110063.4770.26370546.819500.494203.703603.08830K562PUS1
DCPSENSG00000110063.4706.33780532.771000.406703.316102.67610K562RBM15
DCPSENSG00000110063.4425.02970245.320800.792804.942003.84800K562RPS19
DCPSENSG00000110063.4531.61670298.734800.831403.118901.81840K562SF1
DCPSENSG00000110063.4341.14310234.325700.541803.079202.33700K562SRSF1
DCPSENSG00000110063.4282.08620416.43200-0.561903.205301.83800K562STAU1
DCPSENSG00000110063.4497.56050304.415800.708706.596205.31980K562SYNCRIP
DCPSENSG00000110063.4155.99980246.79640-0.661803.291802.17680K562UCHL5
DCPSENSG00000110063.4259.92770431.36480-0.730804.025203.17330K562UPF1
DCPSENSG00000110063.4347.92180515.54690-0.567304.308103.19350K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DCPS is not available on ENCORE database.






No RBPs affect the alternative splcing events of DCPS on ENCORE database.





The Knockdown/knockout RNA-Seq assay for DCPS is not avaliable on ENCORE database.