CCDC66

General Information

Gene Name       : CCDC66
Gene ID             : ENSG00000180376.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CCDC66)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CCDC66ENSG00000180376.1620.0013.9716.98ENCSR000AEF
HepG2CCDC66ENSG00000180376.166.6014.3110.46ENCSR985KAT
K562CCDC66ENSG00000180376.1617.4619.8918.68ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CCDC66 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CCDC66 RNA is bound by 13 proteins.  







eCLIP assay for CCDC66 is not avaliable on ENCORE database.





13 proteins are bound to CCDC66 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr35660062656600706+3'-UTR,CDS,intron-Distal4.385593.45943HepG2BCLAF1
chr35660100356601085+3'-UTR,5'-UTR,CDS,intron-Proximal3.048044.34780K562ZNF622
chr35664767456647768+3'-UTR,CDS3.471094.80070K562GRWD1
chr35660100756601036+3'-UTR,5'-UTR,CDS3.068113.49168K562AQR
chr35665217756652233+3'-UTR,CDS,intron-Proximal4.247893.35169HepG2U2AF2
chr35660076456600861+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal6.9730826.80084K562AQR
chr35664766156647770+3'-UTR,CDS4.214556.40330K562UCHL5
chr35659807356598153+3'-UTR,5'-UTR,CDS,intron-Distal4.665303.45943HepG2BCLAF1
chr35659780956597866+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.080343.02457HepG2BCLAF1
chr35664762756647767+3'-UTR,CDS,intron-Proximal4.751087.20775K562TRA2A
chr35660094456601007+3'-UTR,5'-UTR,CDS,intron-Proximal5.0374117.14889K562AQR
chr35660099756601083+3'-UTR,5'-UTR,CDS,intron-Proximal4.523403.45943HepG2BCLAF1
chr35665157356651640+3'-UTR,CDS,intron-Proximal3.032393.70975K562UCHL5
chr35660520856605294+5'-UTR,CDS,intron-Distal,intron-Proximal3.683585.30520K562UCHL5
chr35660521556605296+5'-UTR,CDS,intron-Distal4.636094.34038HepG2BCLAF1
chr35659289456592941+5'-UTR,CDS,intron-Proximal3.752115.14848K562ZNF622
chr35659359456593625+5'-UTR,CDS,intron-Distal,intron-Proximal4.128153.20027K562ZNF622
chr35660077056600887+CDS,intron-Distal,intron-Proximal3.287997.57294K562KHSRP
chr35661264456612685+intron-Distal4.507023.89080K562EXOSC5
chr35664708256647141+intron-Distal4.164654.28571K562HNRNPM
chr35664342756643507+intron-Distal5.196277.71312K562EXOSC5
chr35660950056609546+intron-Distal3.846053.01445K562EXOSC5
chr35664638956646440+intron-Distal4.338503.89080K562EXOSC5
chr35663332156633366+intron-Distal4.749735.12361K562EXOSC5
chr35661190456611947+intron-Distal4.360933.59909K562EXOSC5
chr35664142156641495+intron-Distal4.553578.51158K562EXOSC5
chr35664657256646646+intron-Distal5.160738.03988K562EXOSC5
chr35660084956600938+intron-Distal,intron-Proximal4.001623.49140K562RBFOX2
chr35660609856606224+intron-Distal3.193514.13575K562KHSRP
chr35664486256644935+intron-Distal5.2581510.00762K562HNRNPM
chr35659130756591419+intron-Distal,intron-Proximal4.669335.32062K562EFTUD2
chr35661250756612545+intron-Distal4.064763.30687K562EXOSC5
chr35661149356611533+intron-Distal4.014993.30696K562EXOSC5
chr35661440056614460+intron-Distal4.841036.41216K562EXOSC5
chr35664497956645037+intron-Distal4.669646.09831K562HNRNPM
chr35662939256629476+intron-Distal3.841363.05187HepG2QKI
chr35664635156646430+intron-Distal3.482444.80898K562HNRNPM
chr35664250556642557+intron-Distal4.719036.08869K562EXOSC5
chr35664486556644919+intron-Distal4.508644.31871HepG2HNRNPM
chr35662587556625995+intron-Distal4.334715.02888K562KHSRP
chr35659819756598278+intron-Distal,intron-Proximal4.086204.07352K562KHSRP
chr35664629256646340+intron-Distal4.299503.89085K562EXOSC5
chr35663301956633092+intron-Distal5.7681013.65583K562EXOSC5
chr35664689556646955+intron-Distal4.143373.60235HepG2HNRNPM
chr35664645256646501+intron-Distal4.283174.52011K562HNRNPM
chr35663504556635095+intron-Distal4.007023.01445K562EXOSC5
chr35661270656612755+intron-Distal5.229418.36716K562EXOSC5
chr35663043456630511+intron-Distal3.708504.02241K562EXOSC5
chr35664678056646825+intron-Distal4.219743.29197K562HNRNPM
chr35664485056644905+intron-Distal4.118213.59909K562EXOSC5
chr35663274956632788+intron-Distal4.375503.01445K562EXOSC5
chr35663080356630846+intron-Distal4.385064.48560K562EXOSC5
chr35663365356633700+intron-Distal4.784656.73640K562EXOSC5
chr35664687956646962+intron-Distal4.974107.90619K562HNRNPM
chr35664154356641604+intron-Distal4.534544.80466K562EXOSC5
chr35664732356647372+intron-Distal4.053573.01445K562EXOSC5
chr35661161156611653+intron-Distal4.013005.50856K562EXOSC5
chr35663727156637325+intron-Distal5.015988.03988K562EXOSC5
chr35660091556600961+intron-Proximal3.667993.24603K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CCDC66 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CCDC66 is not available on ENCORE database.

  • 57 RBPs can affect the levels of CCDC66.  








The Knockdown/knockout RNA-Seq assay for CCDC66 is not available on ENCORE database.





57 RBPs can affect the gene expression of CCDC66 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CCDC66ENSG00000180376.12352.01310504.82550-0.520203.383302.72860HepG2BOP1
CCDC66ENSG00000180376.12354.77510463.46370-0.385601.888801.30920HepG2CPSF6
CCDC66ENSG00000180376.12268.59540198.343500.437301.889501.31640HepG2DDX21
CCDC66ENSG00000180376.12283.41910194.230800.545102.805101.88400HepG2DDX24
CCDC66ENSG00000180376.12335.54150526.29500-0.649402.942601.93550HepG2DDX59
CCDC66ENSG00000180376.12102.88440164.59550-0.677902.229501.66930HepG2DDX6
CCDC66ENSG00000180376.12306.23900227.065100.431502.295601.66870HepG2DKC1
CCDC66ENSG00000180376.12115.22910212.59970-0.883605.411404.45680HepG2DNAJC21
CCDC66ENSG00000180376.12256.37600174.879900.551802.253601.67480HepG2EIF4A3
CCDC66ENSG00000180376.12272.01090170.259900.675802.696002.01580HepG2EIF4B
CCDC66ENSG00000180376.12257.41280176.430300.544902.272701.64320HepG2FXR1
CCDC66ENSG00000180376.12252.51730173.749300.539302.244401.44610HepG2G3BP2
CCDC66ENSG00000180376.12318.45480525.38980-0.722304.989104.14570HepG2GPKOW
CCDC66ENSG00000180376.12257.97540340.19300-0.399102.299001.64070HepG2HNRNPF
CCDC66ENSG00000180376.12273.06080165.714400.720403.701402.90260HepG2HNRNPK
CCDC66ENSG00000180376.12383.08760501.38760-0.388301.916901.38470HepG2HNRNPLL
CCDC66ENSG00000180376.12360.81280156.122201.208502.707301.73430HepG2IGF2BP3
CCDC66ENSG00000180376.12344.40200176.491900.964406.665105.65950HepG2MAGOH
CCDC66ENSG00000180376.12315.54480181.665100.796504.578703.77500HepG2NCBP2
CCDC66ENSG00000180376.12233.12080150.809800.628203.436102.77570HepG2PCBP1
CCDC66ENSG00000180376.12405.42980245.060200.726202.765901.54930HepG2PRPF6
CCDC66ENSG00000180376.12268.91250153.452100.809205.459104.74550HepG2PTBP1
CCDC66ENSG00000180376.12295.11800166.197700.828305.549304.71040HepG2QKI
CCDC66ENSG00000180376.12246.77420150.833100.710102.496701.85240HepG2RBM25
CCDC66ENSG00000180376.12318.94540170.779500.901106.979506.18910HepG2NELFE
CCDC66ENSG00000180376.12322.33980159.054101.019003.722503.02220HepG2RECQL
CCDC66ENSG00000180376.12618.03470364.038500.763505.129504.19230HepG2SF3A3
CCDC66ENSG00000180376.12382.36610496.28480-0.376201.928501.33290HepG2SF3B1
CCDC66ENSG00000180376.12277.10610159.767900.794405.202004.43440HepG2SF3B4
CCDC66ENSG00000180376.12210.32160292.23150-0.474502.882002.16750HepG2SLBP
CCDC66ENSG00000180376.12390.78710552.20020-0.498802.129101.44600HepG2SNRNP70
CCDC66ENSG00000180376.12466.07140166.761301.4827021.4474020.39400HepG2SRSF1
CCDC66ENSG00000180376.12260.21090334.22730-0.361101.904501.31570HepG2SRSF7
CCDC66ENSG00000180376.12459.30300345.626900.410103.026802.49560HepG2SSB
CCDC66ENSG00000180376.12263.29560165.338700.671203.273202.06840HepG2STIP1
CCDC66ENSG00000180376.12284.24770149.886500.923207.020906.19740HepG2TAF15
CCDC66ENSG00000180376.12146.15860232.51240-0.669804.025903.37100HepG2TRIM56
CCDC66ENSG00000180376.12450.95770276.888400.703604.151603.38920HepG2U2AF1
CCDC66ENSG00000180376.12209.62500131.948300.667703.058902.26250HepG2UCHL5
CCDC66ENSG00000180376.12370.77890247.383300.583702.693301.65220HepG2XRCC6
CCDC66ENSG00000180376.12314.16840219.876100.514702.205601.55220HepG2XRN2
CCDC66ENSG00000180376.12356.42880283.580300.329801.886401.31710HepG2ZC3H8
CCDC66ENSG00000180376.12741.98080978.85970-0.399703.124902.50850K562AQR
CCDC66ENSG00000180376.12618.60020892.58550-0.529004.273703.18080K562BOP1
CCDC66ENSG00000180376.12634.53410949.03360-0.580806.522905.31660K562CPSF6
CCDC66ENSG00000180376.12313.61320414.65160-0.402902.360201.39700K562CSTF2
CCDC66ENSG00000180376.12596.84640789.54950-0.403703.755302.93970K562EIF2S2
CCDC66ENSG00000180376.12375.84040499.43280-0.410202.801702.00040K562EIF3G
CCDC66ENSG00000180376.12676.57680937.73160-0.470903.515202.54960K562FIP1L1
CCDC66ENSG00000180376.12748.93560965.69830-0.366702.509401.69560K562FMR1
CCDC66ENSG00000180376.12841.62830573.385500.553603.542702.72070K562G3BP2
CCDC66ENSG00000180376.12548.16190906.06080-0.725008.371206.98340K562GPKOW
CCDC66ENSG00000180376.12845.339201052.20960-0.315802.187301.51060K562GRSF1
CCDC66ENSG00000180376.12856.464501092.04330-0.350602.833001.76110K562HNRNPL
CCDC66ENSG00000180376.12573.21290771.23940-0.428102.372901.51360K562HNRNPM
CCDC66ENSG00000180376.12614.42350884.43020-0.525504.950203.75850K562METAP2
CCDC66ENSG00000180376.12754.08890883.67280-0.228801.958101.31720K562NSUN2
CCDC66ENSG00000180376.12755.066501064.42680-0.495403.400502.47520K562PPIG
CCDC66ENSG00000180376.121194.850901511.66350-0.339303.340802.28500K562PUM2
CCDC66ENSG00000180376.121246.76290915.915500.444803.421602.82690K562PUS1
CCDC66ENSG00000180376.12670.39460530.841600.336602.359401.60140K562SYNCRIP
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CCDC66 is not available on ENCORE database.





17 RBPs can affect the splicing of CCDC66 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECCDC66ENSG00000180376.12chr3+5660636456606456566052085660533056626997566271290.551000.000020.00076includedK562SRSF1
SECCDC66ENSG00000180376.12chr3+5659916156599232565979975659815356600621566007340.248000.000610.01393includedK562SRSF1
SECCDC66ENSG00000180376.12chr3+566521995665224056651139566516335665329856653555-0.323000.000080.00255excludedK562SF3B4
SECCDC66ENSG00000180376.12chr3+5659916156599232565979975659815356600621566007340.222000.000000.00016includedK562PUM1
SECCDC66ENSG00000180376.12chr3+566063645660645656605208566053305662699756627089-0.225000.000780.01141excludedHepG2U2AF2
SECCDC66ENSG00000180376.12chr3+566521995665224056651139566516335665329856653555-0.098000.008450.07111excludedK562AQR
SECCDC66ENSG00000180376.12chr3+566006215660076856597711565981535660097756601081-0.228000.000680.01241excludedK562PUS1
SECCDC66ENSG00000180376.12chr3+5659916156599232565977115659815356600621566007340.142000.000390.07127includedK562APOBEC3C
SECCDC66ENSG00000180376.12chr3+5659916156599232565979975659815356600621566007340.205000.000000.00233includedK562PUM2
SECCDC66ENSG00000180376.12chr3+5659916156599232565977115659815356600621566007340.319000.000000.00000includedK562EIF4G2
SECCDC66ENSG00000180376.12chr3+5659916156599232565977115659815356600621566007340.352000.000010.00710includedHepG2NOL12
SECCDC66ENSG00000180376.12chr3+565935965659362256592873565929385659771156598153-0.316000.001110.04382excludedK562SF3B1
SECCDC66ENSG00000180376.12chr3+5659916156599232565977115659815356600621566007340.299000.000070.00463includedK562PTBP1
A3SSCCDC66ENSG00000180376.12chr3+5662793956628056566279715662805656627587566277690.080000.006010.03395longerK562AQR
A3SSCCDC66ENSG00000180376.12chr3+566476165664777856647638566477785662797156628056-0.147000.000180.01181shorterK562PUS1
A5SSCCDC66ENSG00000180376.12chr3+566006215660078756600621566007685660097756601081-0.319000.000030.00381shorterK562HNRNPC
A5SSCCDC66ENSG00000180376.12chr3+566006215660078756600621566007685660097756601081-0.349000.000080.04735shorterHepG2RBFOX2
MXECCDC66ENSG00000180376.12chr3+56605208566053305662699756627129566009775660108156627518566277690.484000.002160.053441includedHepG2MATR3
MXECCDC66ENSG00000180376.12chr3+56597711565981535660062156600787565935965659362256600977566010810.361000.000850.018021includedK562PUS1
MXECCDC66ENSG00000180376.12chr3+5659359656593622566006215660076856592873565929385660097756601081-0.378000.000010.000832includedK562SF3B1
MXECCDC66ENSG00000180376.12chr3+56600977566010815660519456605330565928735659293856626997566271290.241000.005100.036511includedK562AQR
MXECCDC66ENSG00000180376.12chr3+5659359656593622566009775660108156592872565929385662699756627129-0.194000.006930.047072includedK562AQR
MXECCDC66ENSG00000180376.12chr3+5659359656593622566006215660076856592873565929385660097756601081-0.273000.000510.009232includedK562U2AF2
MXECCDC66ENSG00000180376.12chr3+56599161565992325660062156600787565977115659815356600977566010810.222000.000000.000001includedK562EIF4G2
MXECCDC66ENSG00000180376.12chr3+56599161565992325660062156600768565977115659815356600977566010810.270000.000000.000001includedK562EIF4G2
MXECCDC66ENSG00000180376.12chr3+5660520856605330566269975662712956600977566010815662751856627769-0.434000.001800.050912includedK562EFTUD2
MXECCDC66ENSG00000180376.12chr3+5660520856605330566269975662712956600977566010815662751856627769-0.564000.000060.044792includedK562SLBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CCDC66 is not avaliable on ENCORE database.