APBB2

General Information

Gene Name       : APBB2
Gene ID             : ENSG00000163697.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: APBB2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878APBB2ENSG00000163697.1614.7413.5014.12ENCSR000AEF
HepG2APBB2ENSG00000163697.1615.2614.9815.12ENCSR985KAT
K562APBB2ENSG00000163697.161.440.961.20ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for APBB2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • APBB2 RNA is bound by 14 proteins.  







eCLIP assay for APBB2 is not avaliable on ENCORE database.





14 proteins are bound to APBB2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr44114505341145164-5'-UTR,intron-Distal,intron-Proximal3.176663.71797HepG2BCLAF1
chr44121640841216503-5'-UTR,intron-Distal,intron-Proximal4.109134.62090HepG2SRSF1
chr44089534740895433-CDS,intron-Distal,intron-Proximal4.668164.34038HepG2BCLAF1
chr44101559741015797-CDS,intron-Distal,intron-Proximal4.150827.50845HepG2GRWD1
chr44093646840936534-CDS,intron-Distal,intron-Proximal4.491344.34038HepG2BCLAF1
chr44093667940936730-CDS,intron-Distal,intron-Proximal3.566615.76944HepG2U2AF2
chr44093714740937199-CDS,intron-Distal,intron-Proximal3.689973.80334HepG2U2AF2
chr44101562241015813-CDS,intron-Distal3.211867.13168HepG2BCLAF1
chr44082786440827874-intron-Distal,intron-Proximal5.309469.60492HepG2RBM22
chr44100197041002067-intron-Distal4.452784.51080HepG2HNRNPL
chr44121591141216067-intron-Distal3.101444.49736HepG2NKRF
chr44100197141002045-intron-Distal3.956613.58932HepG2AGGF1
chr44094481740944897-intron-Distal3.994043.29248HepG2SUGP2
chr44121632641216409-intron-Distal4.627335.66020HepG2TIAL1
chr44096467540964783-intron-Distal5.9604415.19890HepG2PCBP2
chr44082781240827864-intron-Distal,intron-Proximal5.5396512.12214HepG2RBM22
chr44091001040910069-intron-Distal4.853055.82272HepG2HNRNPL
chr44094676940946818-intron-Distal,intron-Proximal3.569823.62357HepG2U2AF2
chr44093678540936913-intron-Distal,intron-Proximal3.691763.48223HepG2RBFOX2
chr44089037440890460-intron-Distal4.182383.86368HepG2HNRNPM
chr44102186141022013-intron-Distal4.833347.13376HepG2PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for APBB2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for APBB2 is not available on ENCORE database.

  • 76 RBPs can affect the levels of APBB2.  








The Knockdown/knockout RNA-Seq assay for APBB2 is not available on ENCORE database.





76 RBPs can affect the gene expression of APBB2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
APBB2ENSG00000163697.121094.04500656.777700.736104.947703.72450HepG2ABCF1
APBB2ENSG00000163697.12694.50450416.415200.737907.057205.55560HepG2ADAR
APBB2ENSG00000163697.12633.69270420.582100.591306.702505.56280HepG2AKAP8L
APBB2ENSG00000163697.12327.05590514.71290-0.654203.813702.71290HepG2BCCIP
APBB2ENSG00000163697.12468.60640898.91420-0.9398012.3696011.22620HepG2BOP1
APBB2ENSG00000163697.12773.35250483.579100.677305.875504.77810HepG2CIRBP
APBB2ENSG00000163697.12688.74080418.515200.7186010.934709.79130HepG2CKAP4
APBB2ENSG00000163697.12248.02480427.02260-0.783807.592805.92620HepG2YBX3
APBB2ENSG00000163697.12444.80550317.946200.484302.881301.78400HepG2CSTF2
APBB2ENSG00000163697.12507.73560618.55830-0.284801.864901.31800HepG2CELF1
APBB2ENSG00000163697.12497.75170665.10530-0.418204.193803.31060HepG2DAZAP1
APBB2ENSG00000163697.12229.23420383.38570-0.742005.062403.23670HepG2DDX28
APBB2ENSG00000163697.12402.83280589.27180-0.548803.537802.84020HepG2DDX3X
APBB2ENSG00000163697.12647.11430400.529500.692008.415907.36120HepG2DKC1
APBB2ENSG00000163697.12259.16680486.61850-0.908907.505306.56540HepG2EIF2S1
APBB2ENSG00000163697.12708.25080498.404300.506804.653103.15830HepG2EIF2S2
APBB2ENSG00000163697.12854.50220523.604200.706504.789303.89950HepG2EIF4B
APBB2ENSG00000163697.12814.67430656.164400.312102.545501.73620HepG2EIF4G1
APBB2ENSG00000163697.121742.43850936.655400.8954025.3841023.87740HepG2ETF1
APBB2ENSG00000163697.12694.52260409.057800.763608.680907.21720HepG2EWSR1
APBB2ENSG00000163697.12224.33950343.00230-0.612504.186602.71900HepG2FAM120A
APBB2ENSG00000163697.12904.34120663.238100.447202.927202.13570HepG2FIP1L1
APBB2ENSG00000163697.12445.13160314.025400.503303.117202.28610HepG2FUBP3
APBB2ENSG00000163697.12379.59260503.33270-0.407102.022901.45070HepG2G3BP1
APBB2ENSG00000163697.12712.92750534.372100.415802.547601.69520HepG2G3BP2
APBB2ENSG00000163697.12491.74420341.691500.525103.460002.44530HepG2GEMIN5
APBB2ENSG00000163697.12452.38840611.24930-0.434203.663702.61290HepG2HNRNPA2B1
APBB2ENSG00000163697.12293.79910470.87640-0.680504.925504.02030HepG2HNRNPC
APBB2ENSG00000163697.12440.11520605.86100-0.461104.630903.77570HepG2HNRNPL
APBB2ENSG00000163697.12770.67320511.621200.590904.631003.77770HepG2IGF2BP2
APBB2ENSG00000163697.12376.08370554.96080-0.561302.905301.62600HepG2KRR1
APBB2ENSG00000163697.12317.67770659.51690-1.0538016.1112014.35580HepG2NOL12
APBB2ENSG00000163697.12345.36980463.01550-0.422903.073402.18440HepG2PARN
APBB2ENSG00000163697.12725.65300475.176300.610707.457906.53980HepG2PCBP1
APBB2ENSG00000163697.12378.47100553.07180-0.547302.777901.73460HepG2PCBP2
APBB2ENSG00000163697.12245.54630401.23350-0.708404.453202.34440HepG2PHF6
APBB2ENSG00000163697.121079.47490635.545900.764209.905908.57550HepG2PRPF4
APBB2ENSG00000163697.12566.76710390.412300.537702.515201.74350HepG2PRPF8
APBB2ENSG00000163697.12608.85590483.479700.332502.449801.93000HepG2PTBP1
APBB2ENSG00000163697.12375.22880667.82320-0.8317010.138908.89700HepG2PUM2
APBB2ENSG00000163697.12737.84670426.423600.7909012.9747011.80910HepG2PUS1
APBB2ENSG00000163697.121112.84210782.868800.507306.429005.71810HepG2RBM22
APBB2ENSG00000163697.12722.43910475.253000.604105.628404.69900HepG2RBM25
APBB2ENSG00000163697.12606.78520409.603700.566902.636801.60440HepG2RCC2
APBB2ENSG00000163697.12716.24950538.091400.412503.373202.78830HepG2NELFE
APBB2ENSG00000163697.12792.53840501.113900.661208.606407.60960HepG2RECQL
APBB2ENSG00000163697.121035.98970784.051100.401902.304301.67250HepG2RPLP0
APBB2ENSG00000163697.12759.66170524.275400.534902.819301.86730HepG2RPS10
APBB2ENSG00000163697.121056.51530678.818700.638103.818703.02150HepG2SF3A3
APBB2ENSG00000163697.12757.59590503.418500.589606.787605.92600HepG2SF3B4
APBB2ENSG00000163697.12490.98890603.65310-0.298002.223101.58300HepG2SLBP
APBB2ENSG00000163697.121417.75390884.218300.6810015.1665014.24280HepG2SRFBP1
APBB2ENSG00000163697.121164.74180525.438001.1483029.2632028.08580HepG2SRSF1
APBB2ENSG00000163697.12467.62350621.60310-0.410603.563502.86960HepG2SRSF5
APBB2ENSG00000163697.121025.70350767.705200.417905.224804.56360HepG2SSB
APBB2ENSG00000163697.12506.04280706.93510-0.482305.578904.75230HepG2SUCLG1
APBB2ENSG00000163697.12265.49910448.03990-0.754903.958002.84490HepG2SUPT6H
APBB2ENSG00000163697.121179.47620472.223301.3205034.6575032.95960HepG2TAF15
APBB2ENSG00000163697.12205.25530337.67510-0.718203.777302.63230HepG2TFIP11
APBB2ENSG00000163697.12271.91630458.58120-0.754008.576207.66980HepG2TRIM56
APBB2ENSG00000163697.12434.88680615.05720-0.500103.875902.82100HepG2TUFM
APBB2ENSG00000163697.121097.34840512.580901.098103.577602.45260HepG2U2AF2
APBB2ENSG00000163697.12385.41470651.02720-0.756305.272704.09830HepG2UBE2L3
APBB2ENSG00000163697.12391.80800297.607300.396601.955401.31740HepG2UCHL5
APBB2ENSG00000163697.12396.07360602.00450-0.604004.974604.08100HepG2UPF1
APBB2ENSG00000163697.12311.27470461.33300-0.567602.584301.61680HepG2UPF2
APBB2ENSG00000163697.12879.62910627.241500.487806.406705.45430HepG2ZC3H8
APBB2ENSG00000163697.1213.2278057.60990-2.122705.638904.68920K562AKAP8L
APBB2ENSG00000163697.1223.0775064.95830-1.493004.205702.37760K562DDX19B
APBB2ENSG00000163697.1265.9578016.909701.963606.307005.28610K562EIF2S2
APBB2ENSG00000163697.1249.5043015.859101.642103.382402.43270K562FMR1
APBB2ENSG00000163697.1291.0685022.541602.014306.990505.78090K562GRSF1
APBB2ENSG00000163697.12118.2800024.668302.2614010.740509.19870K562HSPD1
APBB2ENSG00000163697.1224.5269061.13830-1.317702.991002.13160K562KIF1C
APBB2ENSG00000163697.1247.6885014.753101.692503.902102.95570K562MTPAP
APBB2ENSG00000163697.1218.9558048.00680-1.340602.199901.43390K562NAA15
APBB2ENSG00000163697.1260.5644023.402601.371703.239201.68940K562PNPT1
APBB2ENSG00000163697.1215.9563057.13280-1.840204.484103.81620K562PUS1
APBB2ENSG00000163697.1216.8232055.66760-1.726404.123603.41620K562RBM15
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for APBB2 is not available on ENCORE database.





6 RBPs can affect the splicing of APBB2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEAPBB2ENSG00000163697.12chr4-4093709340937156409366304093671640946881409470900.345000.000450.03270includedHepG2AKAP1
SEAPBB2ENSG00000163697.12chr4-4093709340937156409366304093671640946881409470900.317000.000010.04017includedHepG2UTP18
SEAPBB2ENSG00000163697.12chr4-409370934093715640936630409367164094688140947090-0.418000.000070.00844excludedHepG2HNRNPL
SEAPBB2ENSG00000163697.12chr4-410352524103532141015599410164154110265541102767-0.254000.001030.03148excludedHepG2SF3A3
SEAPBB2ENSG00000163697.12chr4-409370934093715640936630409367164094688140947090-0.479000.000000.00000excludedHepG2RBFOX2
SEAPBB2ENSG00000163697.12chr4-409370934093715640936630409367164094688140947090-0.542000.000010.00453excludedHepG2XRCC6
MXEAPBB2ENSG00000163697.12chr4-4110265541102767411450034114515941016304410164154121642141216535-0.646000.001700.052682includedHepG2SF3A3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for APBB2 is not avaliable on ENCORE database.