VPS8

General Information

Gene Name       : VPS8
Gene ID             : ENSG00000156931.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: VPS8)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878VPS8ENSG00000156931.1515.1912.5013.84ENCSR000AEF
HepG2VPS8ENSG00000156931.1511.5717.8814.72ENCSR985KAT
K562VPS8ENSG00000156931.1514.5615.7315.14ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for VPS8 is not avaliable on ENCORE database.



Proteins bound to RNA
  • VPS8 RNA is bound by 19 proteins.  







eCLIP assay for VPS8 is not avaliable on ENCORE database.





19 proteins are bound to VPS8 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3184557467184557541+3'-UTR,CDS,intron-Distal,intron-Proximal3.899898.26514HepG2U2AF2
chr3184616390184616423+3'-UTR,CDS3.991343.06595HepG2BCLAF1
chr3184612665184612714+3'-UTR,CDS,intron-Distal,intron-Proximal3.263853.94979HepG2BCLAF1
chr3184632764184632819+3'-UTR,CDS,intron-Proximal6.428797.17157K562PUM2
chr3184552480184552534+3'-UTR,CDS,intron-Proximal3.091934.68592HepG2PPIG
chr3184556710184556777+3'-UTR,intron-Distal3.157903.05068HepG2U2AF2
chr3184556555184556609+3'-UTR,intron-Proximal4.591955.33214K562PRPF8
chr3184557441184557496+3'-UTR,CDS,intron-Distal,intron-Proximal5.230164.40745K562SF3B4
chr3184633154184633193+3'-UTR,CDS4.261623.38968HepG2BCLAF1
chr3184631316184631350+3'-UTR,CDS,intron-Proximal5.108795.76540K562PUM2
chr3184556573184556667+3'-UTR,intron-Distal,intron-Proximal4.556436.16999K562TIA1
chr3184556495184556628+3'-UTR,CDS,intron-Proximal5.732098.41916K562EFTUD2
chr3184535061184535142+5'-UTR,intron-Distal,intron-Proximal4.341633.19125K562GTF2F1
chr3184648288184648347+CDS3.728303.68471HepG2BCLAF1
chr3184587257184587308+CDS,intron-Proximal4.185133.45799HepG2U2AF2
chr3184573500184573546+CDS4.127123.49905HepG2PPIG
chr3184587278184587316+CDS3.445385.15776HepG2BCLAF1
chr3184580684184580825+CDS,intron-Proximal3.091503.21309HepG2GRWD1
chr3184542505184542574+CDS,intron-Proximal3.668133.14999HepG2GRWD1
chr3184571735184571799+CDS,intron-Proximal3.409623.07653K562ZNF622
chr3184542527184542574+CDS,intron-Proximal4.877105.23259HepG2BCLAF1
chr3184573498184573535+CDS,intron-Proximal3.998595.06180HepG2BCLAF1
chr3184570327184570356+CDS,intron-Proximal4.491344.34038HepG2BCLAF1
chr3184566848184566927+CDS,intron-Proximal3.238933.46866HepG2U2AF2
chr3184571939184571962+CDS,intron-Proximal4.526884.70478HepG2BCLAF1
chr3184571644184571680+CDS,intron-Proximal5.136024.48364K562DDX24
chr3184637926184637982+CDS5.102546.37937HepG2BCLAF1
chr3184580764184580864+CDS,intron-Proximal3.906365.03335K562UCHL5
chr3184571652184571717+CDS3.894446.39464HepG2BCLAF1
chr3184566810184566865+CDS,intron-Proximal5.200717.36555K562SF3B4
chr3184612791184612917+intron-Distal,intron-Proximal4.087493.49011K562KHSRP
chr3184621745184621845+intron-Distal4.237274.31512K562KHSRP
chr3184594766184594917+intron-Distal4.128813.16986HepG2QKI
chr3184603582184603664+intron-Distal4.4419311.61338HepG2U2AF2
chr3184697737184697790+intron-Distal4.014993.30696K562EXOSC5
chr3184531854184531920+intron-Distal4.051783.92684K562KHSRP
chr3184559153184559228+intron-Distal3.223513.28806K562KHSRP
chr3184641200184641350+intron-Distal3.909343.09122HepG2PTBP1
chr3184566740184566826+intron-Distal,intron-Proximal3.727245.78005K562KHSRP
chr3184531711184531753+intron-Distal,intron-Proximal4.305633.45799HepG2U2AF2
chr3184723565184723643+intron-Distal3.422063.72952K562EXOSC5
chr3184603408184603541+intron-Distal3.234004.96160K562KHSRP
chr3184531661184531755+intron-Distal,intron-Proximal3.276053.93901K562KHSRP
chr3184531819184531854+intron-Distal4.047703.06150K562KHSRP
chr3184603591184603655+intron-Distal4.410834.90655K562U2AF2
chr3184602216184602340+intron-Distal3.922023.63454HepG2SUGP2
chr3184541176184541288+intron-Distal3.202795.11767HepG2QKI
chr3184621845184621942+intron-Distal4.425405.41654K562KHSRP
chr3184552530184552597+intron-Proximal4.699634.65563K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for VPS8 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for VPS8 is not available on ENCORE database.

  • 42 RBPs can affect the levels of VPS8.  








The Knockdown/knockout RNA-Seq assay for VPS8 is not available on ENCORE database.





42 RBPs can affect the gene expression of VPS8 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
VPS8ENSG00000156931.111354.04500804.968400.750207.103706.29480HepG2AKAP1
VPS8ENSG00000156931.111277.81710896.835600.510707.779606.72130HepG2AUH
VPS8ENSG00000156931.11766.72620585.178000.389702.659402.07160HepG2BOP1
VPS8ENSG00000156931.11896.48430683.024200.392204.754303.92730HepG2CKAP4
VPS8ENSG00000156931.11957.52690578.689000.726408.456107.34060HepG2DDX21
VPS8ENSG00000156931.11438.58440540.40530-0.301201.902101.30730HepG2DNAJC21
VPS8ENSG00000156931.111090.52520847.641300.363403.989603.01760HepG2EIF4G1
VPS8ENSG00000156931.11875.27240667.580000.390702.427201.64660HepG2EWSR1
VPS8ENSG00000156931.11581.16980365.392400.669405.940004.80890HepG2FUBP3
VPS8ENSG00000156931.11427.88940606.86530-0.504103.494202.72120HepG2HNRNPC
VPS8ENSG00000156931.11428.79680782.63500-0.8680016.0589014.55220HepG2HNRNPL
VPS8ENSG00000156931.11426.49240581.17530-0.446502.586701.97450HepG2HNRNPLL
VPS8ENSG00000156931.11700.63810538.399800.379902.580801.79830HepG2MSI2
VPS8ENSG00000156931.11412.66380537.69550-0.381802.784902.04590HepG2PPIL4
VPS8ENSG00000156931.11729.33230458.425600.669806.162005.00740HepG2PRPF8
VPS8ENSG00000156931.11718.16400863.32750-0.265602.399501.83950HepG2PUM1
VPS8ENSG00000156931.11579.39680695.83830-0.264201.999001.45670HepG2PUS1
VPS8ENSG00000156931.11914.22900660.237200.469504.447703.68200HepG2QKI
VPS8ENSG00000156931.111604.72550860.617000.8988021.3296020.16410HepG2RBM22
VPS8ENSG00000156931.11896.68420599.170700.581503.020202.31940HepG2RBM25
VPS8ENSG00000156931.11564.54910749.67700-0.409202.269701.38000HepG2RBM27
VPS8ENSG00000156931.11902.07640678.389800.411003.910903.28870HepG2NELFE
VPS8ENSG00000156931.11617.06160453.500400.444202.850902.05360HepG2RRP9
VPS8ENSG00000156931.11421.20420536.86380-0.350002.661602.02660HepG2SAFB2
VPS8ENSG00000156931.11497.74880709.20950-0.510803.013901.64960HepG2SART3
VPS8ENSG00000156931.111708.59490972.041700.8136022.6121021.53910HepG2SRFBP1
VPS8ENSG00000156931.11879.43130662.440000.408704.011703.46850HepG2SRSF1
VPS8ENSG00000156931.11580.70650706.80210-0.283502.057101.44700HepG2SRSF7
VPS8ENSG00000156931.11952.55460595.333400.678009.438108.50150HepG2TAF15
VPS8ENSG00000156931.11425.16990591.02180-0.475204.742804.04460HepG2TRIM56
VPS8ENSG00000156931.11890.16310740.064000.266302.583602.05020HepG2ZNF622
VPS8ENSG00000156931.11829.088501078.82640-0.379903.943902.61330K562CPEB4
VPS8ENSG00000156931.111404.915301116.462700.331403.893603.13960K562DDX47
VPS8ENSG00000156931.11708.83960870.30800-0.296102.537301.39160K562EIF2S1
VPS8ENSG00000156931.11509.64150827.76900-0.699707.639206.27720K562EIF4A3
VPS8ENSG00000156931.11650.394201008.93980-0.633507.555105.72620K562HNRNPL
VPS8ENSG00000156931.11408.76930682.66060-0.739906.091104.63610K562HNRNPM
VPS8ENSG00000156931.11666.65940985.05690-0.563306.150604.87710K562MAGOH
VPS8ENSG00000156931.11609.18380983.11430-0.690508.959107.20290K562MATR3
VPS8ENSG00000156931.11644.84110942.17720-0.547105.084103.91460K562PPIG
VPS8ENSG00000156931.11761.36790926.58730-0.283302.087601.34670K562SF3B4
VPS8ENSG00000156931.11647.28440938.15460-0.535404.805003.87840K562SRSF1
VPS8ENSG00000156931.11687.27970949.56240-0.466403.759102.92890K562TARDBP
VPS8ENSG00000156931.111085.16390821.191100.402005.443104.29650K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for VPS8 is not available on ENCORE database.





8 RBPs can affect the splicing of VPS8 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEVPS8ENSG00000156931.11chr3+1846402161846402711846379141846379861846426491846427690.295000.006600.09442includedK562SRSF1
SEVPS8ENSG00000156931.11chr3+1846001361846002211845885031845885931846038971846039440.115000.002770.02870includedK562AQR
SEVPS8ENSG00000156931.11chr3+184711770184711851184700799184700882184714119184714289-0.093000.008660.07242excludedK562AQR
SEVPS8ENSG00000156931.11chr3+184640216184640271184637914184637986184642649184642769-0.194000.004230.07152excludedK562U2AF1
SEVPS8ENSG00000156931.11chr3+1846402161846402711846379141846379861846426491846427690.253000.000010.00213includedK562HNRNPM
SEVPS8ENSG00000156931.11chr3+1846622791846623771846579841846580311846751611846753090.065000.002490.06686includedK562UTP18
SEVPS8ENSG00000156931.11chr3+184647367184647452184646238184646321184648257184648356-0.159000.001020.02032excludedK562U2AF2
SEVPS8ENSG00000156931.11chr3+184640216184640271184637914184637986184642649184642769-0.230000.000700.02859excludedK562HNRNPU
A3SSVPS8ENSG00000156931.11chr3+1846473471846474521846473671846474521846462081846463210.180000.004460.02613longerK562AQR
A5SSVPS8ENSG00000156931.11chr3+1846482571846484351846482571846483561846540331846541230.073000.000240.00566longerK562AQR
MXEVPS8ENSG00000156931.11chr3+184556501184556534184557485184557546184552436184552530184566858184566983-0.210000.010020.063462includedK562AQR
MXEVPS8ENSG00000156931.11chr3+184603897184603944184611021184611200184588503184588593184612490184612713-0.372000.000250.013572includedHepG2HNRNPL
MXEVPS8ENSG00000156931.11chr3+184603744184603944184611021184611200184588503184588593184612490184612713-0.420000.000860.034892includedHepG2HNRNPL

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for VPS8 is not avaliable on ENCORE database.