TUSC3

General Information

Gene Name       : TUSC3
Gene ID             : ENSG00000104723.20
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TUSC3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TUSC3ENSG00000104723.200.000.070.04ENCSR000AEF
HepG2TUSC3ENSG00000104723.200.100.250.17ENCSR985KAT
K562TUSC3ENSG00000104723.2051.8147.8949.85ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TUSC3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TUSC3 RNA is bound by 18 proteins.  







eCLIP assay for TUSC3 is not avaliable on ENCORE database.





18 proteins are bound to TUSC3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr81539788315397969+5'-UTR,CDS,intron-Distal3.656164.79053K562FTO
chr81553126015531334+CDS4.233457.95584K562SND1
chr81550821815508265+CDS,intron-Distal4.474815.61640K562YBX3
chr81539800015398062+CDS,intron-Distal3.170467.35825K562DDX3X
chr81553132815531346+CDS,intron-Proximal5.163255.10740K562DDX24
chr81553125415531328+CDS,intron-Proximal4.117285.64813K562DDX24
chr81551701415517146+CDS,intron-Proximal3.094216.21779K562YBX3
chr81551700915517072+CDS,intron-Proximal4.166684.23351K562BUD13
chr81553126615531344+CDS3.485883.34065K562IGF2BP1
chr81548069415480758+CDS3.294664.53005K562YBX3
chr81548068015480760+CDS,intron-Proximal4.562065.44652K562IGF2BP2
chr81553840315538437+intron-Distal3.457253.72952K562EXOSC5
chr81553784215537962+intron-Distal6.5507523.02542K562EXOSC5
chr81555520215555335+intron-Distal3.631305.32884K562KHSRP
chr81554142515541516+intron-Distal4.638415.57532K562HNRNPM
chr81554892715548965+intron-Distal3.812745.50856K562EXOSC5
chr81554000615540094+intron-Distal5.5422111.00212K562EXOSC5
chr81553827215538317+intron-Distal4.926556.73640K562EXOSC5
chr81553856615538597+intron-Distal3.667983.43829K562EXOSC5
chr81542511315425357+intron-Distal3.959323.26999K562KHSRP
chr81554142715541474+intron-Distal4.053573.01445K562EXOSC5
chr81530066315300757+intron-Distal3.563755.45334K562U2AF2
chr81542793315428108+intron-Distal4.512785.25174K562KHSRP
chr81555499115555049+intron-Distal3.415903.34940K562HNRNPM
chr81553908215539104+intron-Distal4.155043.30696K562EXOSC5
chr81555246015552522+intron-Distal4.658185.57532K562HNRNPM
chr81553993515540026+intron-Distal3.610985.14864K562KHSRP
chr81548812815488216+intron-Distal4.792268.06346K562KHSRP
chr81542777015427861+intron-Distal4.173424.94713K562HNRNPL
chr81540957315409651+intron-Distal4.318504.72162K562KHSRP
chr81544002015440134+intron-Distal3.713953.39089K562KHDRBS1
chr81539814815398289+intron-Distal,intron-Proximal4.829457.46888K562NONO
chr81561733315617420+intron-Distal3.758386.87274K562HNRNPL
chr81554039615540431+intron-Distal4.583025.76606K562EXOSC5
chr81555213515552211+intron-Distal4.235283.30687K562EXOSC5
chr81554025815540308+intron-Distal4.283173.53404K562HNRNPM
chr81555018115550233+intron-Distal3.470024.31711K562EXOSC5
chr81554086915540909+intron-Distal4.779186.08869K562EXOSC5
chr81560524215605404+intron-Distal3.077103.40400K562HNRNPL
chr81545420115454337+intron-Distal3.346074.70224K562KHSRP
chr81548198715482071+intron-Distal4.062554.10688K562KHSRP
chr81548494315485002+intron-Distal5.432515.53111K562LSM11
chr81557783015577938+intron-Distal4.475335.74422K562HNRNPL
chr81548500215485061+intron-Distal4.134433.65874K562LSM11
chr81553783415537960+intron-Distal4.497115.44904K562TARDBP
chr81560532315605458+intron-Distal5.6707919.07464K562QKI
chr81539859415398732+intron-Distal4.065884.07352K562KHSRP
chr81554033015540385+intron-Distal5.7843113.98859K562EXOSC5
chr81560483815604901+intron-Distal3.666843.02234K562KHSRP
chr81553924815539291+intron-Distal4.752596.41304K562EXOSC5
chr81554133015541383+intron-Distal5.302839.35180K562EXOSC5
chr81557697615577086+intron-Distal3.131287.72509K562HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TUSC3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TUSC3 is not available on ENCORE database.

  • 47 RBPs can affect the levels of TUSC3.  








The Knockdown/knockout RNA-Seq assay for TUSC3 is not available on ENCORE database.





47 RBPs can affect the gene expression of TUSC3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TUSC3ENSG00000104723.1663.855407.877003.019007.689906.85010HepG2AKAP1
TUSC3ENSG00000104723.1630.856506.518002.243003.358802.49300HepG2ASCC1
TUSC3ENSG00000104723.1635.542902.330403.930806.353605.19470HepG2CNOT7
TUSC3ENSG00000104723.1694.847707.546503.6516014.9746013.63270HepG2DDX3X
TUSC3ENSG00000104723.1627.246106.480402.071802.591701.99330HepG2DDX6
TUSC3ENSG00000104723.1689.248906.704503.734504.894603.99660HepG2EIF4B
TUSC3ENSG00000104723.1623.235104.787302.278902.917102.06130HepG2EWSR1
TUSC3ENSG00000104723.1639.179006.445702.603605.229504.32800HepG2G3BP1
TUSC3ENSG00000104723.1645.094306.552502.782706.034705.07510HepG2IGF2BP2
TUSC3ENSG00000104723.1627.513007.759001.826102.310201.55630HepG2LARP4
TUSC3ENSG00000104723.1615.347202.132802.847102.410101.59260HepG2PABPC1
TUSC3ENSG00000104723.1668.438105.925403.5297012.8283011.67220HepG2PUF60
TUSC3ENSG00000104723.1634.627906.285502.461704.467003.62600HepG2PUM2
TUSC3ENSG00000104723.1696.512505.624704.1008011.7909010.41180HepG2RAVER1
TUSC3ENSG00000104723.16113.801306.804204.0639014.9468013.93840HepG2RBM22
TUSC3ENSG00000104723.1624.286504.702802.368503.340302.59760HepG2SF3A3
TUSC3ENSG00000104723.1643.960901.813504.599309.777208.52320HepG2SF3B1
TUSC3ENSG00000104723.16195.796407.686104.6709025.0870023.97250HepG2SRFBP1
TUSC3ENSG00000104723.1622.385906.771301.725001.699601.30330HepG2SRSF1
TUSC3ENSG00000104723.1622.145301.951103.504502.604601.63670HepG2SRSF3
TUSC3ENSG00000104723.16102.378005.507704.2162023.9834022.65700HepG2SRSF9
TUSC3ENSG00000104723.1618.214504.293702.084702.025401.47870HepG2U2AF1
TUSC3ENSG00000104723.1621.642704.170502.375503.043602.31880HepG2UPF1
TUSC3ENSG00000104723.1658.178004.586903.6648011.9994011.06010HepG2ZNF622
TUSC3ENSG00000104723.161819.077901440.845800.336202.888702.22100K562AKAP8L
TUSC3ENSG00000104723.161028.972601930.58500-0.9078014.6891013.48580K562AQR
TUSC3ENSG00000104723.162085.323001654.826400.333503.547402.18880K562CCDC124
TUSC3ENSG00000104723.16938.594201624.64260-0.7915011.459808.62070K562DDX19B
TUSC3ENSG00000104723.16649.34120881.47400-0.440903.191702.20570K562EFTUD2
TUSC3ENSG00000104723.161513.210001295.414000.224101.990001.36240K562EIF2S2
TUSC3ENSG00000104723.16862.367801078.25460-0.322303.102402.26160K562EIF3G
TUSC3ENSG00000104723.16736.972601050.29980-0.511104.889803.79530K562EIF4A3
TUSC3ENSG00000104723.161338.291701030.226700.377303.146002.23980K562FIP1L1
TUSC3ENSG00000104723.16877.947701092.27020-0.315102.914202.29570K562FXR1
TUSC3ENSG00000104723.161440.556801132.115000.347501.884101.31310K562G3BP2
TUSC3ENSG00000104723.16783.03640970.99640-0.310402.581601.48080K562GLRX3
TUSC3ENSG00000104723.16607.77060790.68190-0.379602.629901.85320K562GPKOW
TUSC3ENSG00000104723.162022.714701396.678900.534206.184705.00660K562HSPD1
TUSC3ENSG00000104723.161662.072501200.686500.469003.095502.15450K562NAA15
TUSC3ENSG00000104723.16844.060101134.21120-0.426306.490405.41130K562NSUN2
TUSC3ENSG00000104723.161506.703501169.603400.365302.919602.07400K562PPIG
TUSC3ENSG00000104723.162474.750901428.974000.7922012.4813011.37420K562PUS1
TUSC3ENSG00000104723.161824.140001392.278200.389704.914304.14450K562RBM15
TUSC3ENSG00000104723.161227.428101637.07670-0.415504.300402.28550K562RBM17
TUSC3ENSG00000104723.16947.559901344.10310-0.504404.016602.98720K562RBM22
TUSC3ENSG00000104723.16925.173301177.64640-0.348103.200702.28080K562SF3B4
TUSC3ENSG00000104723.16631.11970839.84390-0.412203.560402.62910K562SYNCRIP
TUSC3ENSG00000104723.161491.726301133.716100.395804.386203.37930K562U2AF2
TUSC3ENSG00000104723.161458.068201202.635400.277803.291602.51200K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TUSC3 is not available on ENCORE database.





11 RBPs can affect the splicing of TUSC3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETUSC3ENSG00000104723.16chr8+156152991561536415605883156059741562171115621968-0.317000.000000.00000excludedK562SRSF1
SETUSC3ENSG00000104723.16chr8+156152991561536415605883156059741562171115621968-0.330000.000000.00000excludedK562PRPF8
SETUSC3ENSG00000104723.16chr8+156152991561536415605883156059741562171115621968-0.264000.000000.00027excludedK562FXR1
SETUSC3ENSG00000104723.16chr8+1561529915615364156058831560597415621711156219680.192000.000180.09279includedK562SSB
SETUSC3ENSG00000104723.16chr8+1561525215615364156058831560597415621711156219680.204000.000080.02087includedK562UPF1
SETUSC3ENSG00000104723.16chr8+156152991561536415605883156059741562171115621968-0.212000.000220.00571excludedK562U2AF2
SETUSC3ENSG00000104723.16chr8+1561529915615364156058831560597415621711156219680.254000.000370.04435includedK562CPSF6
SETUSC3ENSG00000104723.16chr8+1561529915615364156058951560597415621711156219680.160000.000720.08925includedK562ZC3H8
SETUSC3ENSG00000104723.16chr8+156152991561536415605895156059741562171115621968-0.274000.000320.00732excludedK562HNRNPC
MXETUSC3ENSG00000104723.16chr8+1548058815480758155082051550832315397789153980771551701515517156-0.099000.001720.026592includedK562DROSHA
MXETUSC3ENSG00000104723.16chr8+15605883156059741561529915615364156009521560112115615538156157860.094000.000960.018671includedK562SRSF1
MXETUSC3ENSG00000104723.16chr8+1548058815480758155082051550832315397789153980771551701515517156-0.106000.001010.023462includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TUSC3 is not avaliable on ENCORE database.