TM2D1

General Information

Gene Name       : TM2D1
Gene ID             : ENSG00000162604.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TM2D1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TM2D1ENSG00000162604.1213.7815.8414.81ENCSR000AEF
HepG2TM2D1ENSG00000162604.1214.4523.0018.73ENCSR985KAT
K562TM2D1ENSG00000162604.1223.3123.3623.34ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TM2D1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TM2D1 RNA is bound by 14 proteins.  







eCLIP assay for TM2D1 is not avaliable on ENCORE database.





14 proteins are bound to TM2D1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr16214680162146906-3'-UTR,intron-Distal,intron-Proximal4.516246.88705HepG2SUB1
chr16216318662163230-3'-UTR,intron-Distal3.914827.55138K562KHSRP
chr16216657462166656-3'-UTR,CDS,intron-Distal,intron-Proximal5.7217613.78100HepG2PRPF8
chr16214685562146925-3'-UTR,intron-Distal,intron-Proximal4.4350611.47805HepG2FUBP3
chr16214678862146860-3'-UTR,intron-Distal,intron-Proximal4.274558.38381HepG2DDX55
chr16214681962146855-3'-UTR,intron-Distal,intron-Proximal4.051284.34279HepG2FUBP3
chr16214681362146892-3'-UTR,intron-Distal,intron-Proximal4.616325.77165HepG2TIAL1
chr16214918662149229-3'-UTR,CDS,intron-Distal,intron-Proximal3.346093.55754HepG2U2AF2
chr16216323062163291-3'-UTR,intron-Distal4.064388.11138K562KHSRP
chr16216659462166650-3'-UTR,CDS,intron-Distal,intron-Proximal3.686454.80912HepG2PPIG
chr16218934962189405-5'-UTR,CDS,intron-Distal,intron-Proximal3.879684.54206HepG2PRPF8
chr16219063862190708-CDS,intron-Distal3.9876014.89015HepG2DDX3X
chr16219053662190588-CDS,intron-Distal3.039726.87008HepG2PRPF8
chr16219063762190714-CDS,intron-Distal4.548839.27494K562DDX3X
chr16219071862190793-CDS,intron-Distal,intron-Proximal5.5900821.73822HepG2DDX3X
chr16216993562170018-intron-Distal4.893085.39854K562PTBP1
chr16215805562158091-intron-Distal3.913823.62418K562PTBP1
chr16217603862176085-intron-Distal3.348507.12565HepG2HNRNPC
chr16216993562170023-intron-Distal4.714824.74221HepG2PTBP1
chr16215809662158156-intron-Distal5.8186129.36430HepG2PTBP1
chr16214730062147384-intron-Distal3.555267.46603HepG2KHSRP
chr16214970862149795-intron-Distal4.332859.48825HepG2U2AF2
chr16214725562147300-intron-Distal4.332995.07255HepG2KHSRP
chr16216294862163067-intron-Distal3.807863.95338HepG2CSTF2
chr16216137062161471-intron-Distal5.2073010.05887K562KHSRP
chr16217608562176102-intron-Distal3.115505.25752HepG2HNRNPC
chr16214708062147169-intron-Distal3.409884.76825K562KHSRP
chr16216313262163177-intron-Distal,intron-Proximal4.981654.23016K562FMR1
chr16214724762147295-intron-Distal3.213834.30679K562KHSRP
chr16215145162151519-intron-Distal3.678583.21162HepG2HNRNPC
chr16215806062158085-intron-Distal3.161363.00914HepG2PTBP1
chr16215809162158158-intron-Distal5.2160822.18965K562PTBP1
chr16216308662163177-intron-Distal,intron-Proximal5.002899.95238HepG2CSTF2
chr16218192162182010-intron-Distal3.490084.27938HepG2ILF3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TM2D1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TM2D1 is not available on ENCORE database.

  • 64 RBPs can affect the levels of TM2D1.  








The Knockdown/knockout RNA-Seq assay for TM2D1 is not available on ENCORE database.





64 RBPs can affect the gene expression of TM2D1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TM2D1ENSG00000162604.8279.37660358.13610-0.358302.104001.55940HepG2ACO1
TM2D1ENSG00000162604.8548.71290416.921300.396203.113502.39230HepG2AUH
TM2D1ENSG00000162604.8478.95100376.267400.348002.009401.34470HepG2CALR
TM2D1ENSG00000162604.8778.32380501.223500.634803.436902.57730HepG2CNOT7
TM2D1ENSG00000162604.8459.23950280.568100.710805.185904.27060HepG2CPSF6
TM2D1ENSG00000162604.8561.45490418.830400.422703.315902.62510HepG2CELF1
TM2D1ENSG00000162604.8599.85970450.376500.413403.795302.95050HepG2DAZAP1
TM2D1ENSG00000162604.8213.74970342.65440-0.680805.108404.23870HepG2DKC1
TM2D1ENSG00000162604.8364.97460279.599100.384302.168401.53730HepG2DNAJC21
TM2D1ENSG00000162604.8366.44490277.080700.403202.739402.09080HepG2DNAJC2
TM2D1ENSG00000162604.8263.14650368.77060-0.486902.246501.41400HepG2EEF2
TM2D1ENSG00000162604.8287.12770579.68390-1.013607.591806.48270HepG2EIF4B
TM2D1ENSG00000162604.8675.93460479.264100.496002.444301.71700HepG2FIP1L1
TM2D1ENSG00000162604.8378.44000600.71890-0.666605.072404.15640HepG2FXR1
TM2D1ENSG00000162604.8453.39070591.60030-0.383902.101301.33200HepG2G3BP2
TM2D1ENSG00000162604.8187.85650266.53990-0.504702.278901.47310HepG2GEMIN5
TM2D1ENSG00000162604.8522.82390413.894000.337002.215201.36960HepG2HNRNPA2B1
TM2D1ENSG00000162604.8574.68410410.268000.486104.857903.98280HepG2HNRNPL
TM2D1ENSG00000162604.8452.11830303.522100.574803.507302.80840HepG2HNRNPLL
TM2D1ENSG00000162604.8400.36180311.890200.360202.295401.73810HepG2HNRNPU
TM2D1ENSG00000162604.8353.36560566.42160-0.680705.019404.13460HepG2IGF2BP2
TM2D1ENSG00000162604.8329.74510569.73100-0.788905.315003.88430HepG2KHSRP
TM2D1ENSG00000162604.8442.98860600.92870-0.439902.487901.86540HepG2MAGOH
TM2D1ENSG00000162604.8356.98220604.28850-0.759405.640704.76490HepG2MATR3
TM2D1ENSG00000162604.8541.79320387.813200.482303.103402.24870HepG2MSI2
TM2D1ENSG00000162604.8462.85730309.539900.580302.620201.68030HepG2MTPAP
TM2D1ENSG00000162604.8481.88220325.665400.565203.953602.49950HepG2NAA15
TM2D1ENSG00000162604.8465.63540618.52000-0.409602.197501.63110HepG2NCBP2
TM2D1ENSG00000162604.8565.20690446.590800.339702.164101.48780HepG2NOL12
TM2D1ENSG00000162604.8312.84090523.57990-0.743008.357107.39600HepG2PCBP1
TM2D1ENSG00000162604.8395.60330278.184000.507903.632002.79890HepG2PPIL4
TM2D1ENSG00000162604.8352.06310532.78410-0.597705.542904.82410HepG2PTBP1
TM2D1ENSG00000162604.8600.68170369.996700.699003.423002.64110HepG2RAVER1
TM2D1ENSG00000162604.8710.61930540.887400.393603.263002.34010HepG2RBM15
TM2D1ENSG00000162604.8253.72910361.93830-0.512502.314801.41560HepG2RBM27
TM2D1ENSG00000162604.8282.43100592.91920-1.0699015.2386014.16110HepG2NELFE
TM2D1ENSG00000162604.8302.55980552.25680-0.8681010.615009.52790HepG2RECQL
TM2D1ENSG00000162604.8288.23380191.051200.593202.406901.66870HepG2RRP9
TM2D1ENSG00000162604.8417.24210277.761700.586905.122804.29420HepG2SAFB2
TM2D1ENSG00000162604.8353.09980491.73050-0.477801.988001.41460HepG2SF3A3
TM2D1ENSG00000162604.8506.63740300.430500.753806.152105.13450HepG2SF3B1
TM2D1ENSG00000162604.8210.75800554.65760-1.3960022.7778021.35810HepG2SF3B4
TM2D1ENSG00000162604.8522.26240377.703800.467402.313101.44590HepG2SMNDC1
TM2D1ENSG00000162604.8527.98270334.280300.659303.313102.45440HepG2SNRNP70
TM2D1ENSG00000162604.8821.83280451.877100.8628015.2482014.32160HepG2SRFBP1
TM2D1ENSG00000162604.8369.74450578.95850-0.646906.564005.91040HepG2SRSF1
TM2D1ENSG00000162604.8531.40460323.254300.717004.418003.12510HepG2SRSF3
TM2D1ENSG00000162604.8411.05590305.829300.426502.909502.19860HepG2SRSF7
TM2D1ENSG00000162604.8449.94570323.560500.475603.090702.10220HepG2SUPT6H
TM2D1ENSG00000162604.8395.54000249.280400.666003.223302.50000HepG2SUPV3L1
TM2D1ENSG00000162604.8334.93940520.43510-0.635806.025205.25060HepG2TAF15
TM2D1ENSG00000162604.8453.07850295.824100.614904.125503.26210HepG2TARDBP
TM2D1ENSG00000162604.8276.05610167.076600.724403.332802.24610HepG2TFIP11
TM2D1ENSG00000162604.8412.51070305.764800.431903.021102.43790HepG2TRIM56
TM2D1ENSG00000162604.8612.07320409.938400.578203.779703.04930HepG2U2AF1
TM2D1ENSG00000162604.8279.42290147.249400.924105.909304.78960HepG2UCHL5
TM2D1ENSG00000162604.8302.16690421.02740-0.478602.254101.70190HepG2UTP3
TM2D1ENSG00000162604.8773.66660479.615200.6897011.5322010.60480HepG2ZNF622
TM2D1ENSG00000162604.8981.74770660.471600.571808.424607.50790K562AGGF1
TM2D1ENSG00000162604.8878.26240687.258800.353702.628101.99040K562AKAP8L
TM2D1ENSG00000162604.8580.93480718.29630-0.306202.429201.81310K562DDX47
TM2D1ENSG00000162604.8891.48340739.488700.269602.275001.49170K562DKC1
TM2D1ENSG00000162604.81016.93950729.324800.479503.371602.45080K562KIF1C
TM2D1ENSG00000162604.81022.36270817.032000.323302.480201.62690K562MBNL1
TM2D1ENSG00000162604.8778.09580572.682800.442102.388101.58180K562NAA15
TM2D1ENSG00000162604.81314.50300681.514000.947607.537906.68800K562PUS1
TM2D1ENSG00000162604.8847.34620664.080900.351503.077802.45790K562RBM15
TM2D1ENSG00000162604.8266.43590400.17470-0.586803.732401.73010K562RECQL
TM2D1ENSG00000162604.8226.01320409.85810-0.858708.476906.94000K562SF3B4
TM2D1ENSG00000162604.8383.19270258.110000.570003.089802.01560K562SUPV3L1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TM2D1 is not available on ENCORE database.





17 RBPs can affect the splicing of TM2D1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETM2D1ENSG00000162604.8chr1-6215246362152593621491236214921862160368621604310.131000.000020.00333includedHepG2G3BP1
SETM2D1ENSG00000162604.8chr1-6215246362152593621491236214921862160368621604420.088000.005060.07484includedK562SF3B4
SETM2D1ENSG00000162604.8chr1-621893846218944462175000621751096219057362190816-0.216000.001790.03350excludedK562SF3B4
SETM2D1ENSG00000162604.8chr1-621603686216044262149088621492186216660562166677-0.094000.001030.02151excludedK562SF3B4
SETM2D1ENSG00000162604.8chr1-621524636215256762149168621492186216036862160442-0.132000.000260.03018excludedHepG2PRPF8
SETM2D1ENSG00000162604.8chr1-621893846218944462175000621751096219057362190816-0.213000.000110.03323excludedK562PCBP1
SETM2D1ENSG00000162604.8chr1-6215246362152567621491686214921862160368621604420.151000.000380.03580includedHepG2TBRG4
SETM2D1ENSG00000162604.8chr1-6215246362152567621491686214921862160368621604420.237000.006930.06860includedHepG2U2AF2
SETM2D1ENSG00000162604.8chr1-6215246362152593621491236214921862160368621604310.126000.000000.00067includedHepG2AKAP1
SETM2D1ENSG00000162604.8chr1-621603686216044262148943621492186216660562166697-0.052000.003500.03473excludedK562AQR
SETM2D1ENSG00000162604.8chr1-6215246362152593621491236214921862160368621604420.099000.000700.03867includedHepG2PTBP1
SETM2D1ENSG00000162604.8chr1-6215246362152593621491236214921862160368621604420.108000.000470.02379includedHepG2MATR3
SETM2D1ENSG00000162604.8chr1-6215246362152593621491236214921862160368621604420.079000.005770.09028includedK562U2AF1
SETM2D1ENSG00000162604.8chr1-6215246362152593621491236214921862160368621604310.159000.000280.03692includedHepG2LARP4
SETM2D1ENSG00000162604.8chr1-6215246362152593621491236214921862160368621604310.117000.000300.02557includedK562HNRNPL
SETM2D1ENSG00000162604.8chr1-621524636215256762149168621492186216036862160442-0.120000.000060.02797excludedK562PPIL4
SETM2D1ENSG00000162604.8chr1-6215246362152593621491236214921862160368621604420.266000.000000.00000includedHepG2SRSF1
SETM2D1ENSG00000162604.8chr1-621893846218956662175000621751096219057362190816-0.124000.000240.00990excludedHepG2SF3A3
SETM2D1ENSG00000162604.8chr1-6215246362152593621491236214921862160368621604420.151000.000000.00006includedK562U2AF2
SETM2D1ENSG00000162604.8chr1-6218938462189444621750006217510962190573621908160.136000.002960.08817includedHepG2HNRNPC
SETM2D1ENSG00000162604.8chr1-6215246362152567621491686214921862160368621604420.166000.000790.03206includedHepG2HNRNPC
SETM2D1ENSG00000162604.8chr1-6218995962190097621750006217510962190573621907850.767000.008070.09987includedK562HNRNPC
SETM2D1ENSG00000162604.8chr1-6215246362152593621491236214921862160368621604420.148000.006890.08892includedK562HNRNPC
SETM2D1ENSG00000162604.8chr1-621893846218944462175000621751096218995962190097-0.182000.000630.01308excludedK562HNRNPC
A3SSTM2D1ENSG00000162604.8chr1-6217500062175149621750006217510962190573621908160.622000.008780.04729longerK562AQR
MXETM2D1ENSG00000162604.8chr1-62160368621604426216660562166697621490886214921862175000621751090.133000.003670.062331includedHepG2SRSF1
MXETM2D1ENSG00000162604.8chr1-6216660562166697621750006217510962149088621492186218938462189444-0.064000.000970.008892includedK562AQR
MXETM2D1ENSG00000162604.8chr1-6216660562166697621750026217510962149088621492186218938462189444-0.064000.001010.009182includedK562AQR
MXETM2D1ENSG00000162604.8chr1-6216660562166697621750796217510962149088621492186218938462189444-0.136000.000230.002472includedK562AQR
MXETM2D1ENSG00000162604.8chr1-62149088621492186216036862160442621467206214702262166605621666970.075000.013630.069321includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TM2D1 is not avaliable on ENCORE database.