TK2

General Information

Gene Name       : TK2
Gene ID             : ENSG00000166548.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TK2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TK2ENSG00000166548.152.861.792.33ENCSR000AEF
HepG2TK2ENSG00000166548.1511.3714.9413.15ENCSR985KAT
K562TK2ENSG00000166548.153.442.893.17ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TK2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TK2 RNA is bound by 8 proteins.  







eCLIP assay for TK2 is not avaliable on ENCORE database.





8 proteins are bound to TK2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr166654387366543939-3'-UTR,intron-Distal4.121373.31330K562UPF1
chr166654408166544117-3'-UTR,intron-Distal4.171143.31330K562UPF1
chr166654763866547716-3'-UTR,CDS,intron-Distal,intron-Proximal4.311748.98365HepG2PPIG
chr166655103866551121-3'-UTR,CDS,intron-Distal,intron-Proximal4.1444710.72269HepG2PPIG
chr166654760866547662-3'-UTR,CDS,intron-Distal,intron-Proximal4.884764.35676HepG2PRPF8
chr166657086766570921-5'-UTR,CDS,intron-Distal,intron-Proximal3.261623.55800HepG2BCLAF1
chr166658361166583732-5'-UTR,intron-Distal,intron-Proximal5.2330614.13532HepG2NCBP2
chr166657090466570923-5'-UTR,CDS,intron-Distal,intron-Proximal3.745646.00907HepG2PPIG
chr166657086766570904-5'-UTR,CDS,intron-Distal4.228445.30777HepG2PPIG
chr166657577966575805-5'-UTR,CDS,intron-Distal,intron-Proximal3.902243.56019HepG2GRWD1
chr166657577866575859-5'-UTR,CDS,intron-Distal,intron-Proximal3.706116.81385HepG2BCLAF1
chr166657578066575853-5'-UTR,CDS,intron-Distal,intron-Proximal3.524396.27819HepG2PPIG
chr166657594566576030-intron-Distal,intron-Proximal4.163294.05848HepG2QKI
chr166658376866583836-intron-Distal,intron-Proximal4.885414.13847K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TK2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TK2 is not available on ENCORE database.

  • 58 RBPs can affect the levels of TK2.  








The Knockdown/knockout RNA-Seq assay for TK2 is not available on ENCORE database.





58 RBPs can affect the gene expression of TK2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TK2ENSG00000166548.11696.61820556.424900.324102.818002.20560HepG2ACO1
TK2ENSG00000166548.111113.93490745.845200.578609.344408.20640HepG2AUH
TK2ENSG00000166548.11603.29460413.631400.544403.185402.21900HepG2BCLAF1
TK2ENSG00000166548.11394.42700276.156600.514202.887202.27670HepG2BOP1
TK2ENSG00000166548.11265.31990484.09460-0.867607.125105.92580HepG2CIRBP
TK2ENSG00000166548.11733.76160556.202800.399604.271603.47930HepG2CKAP4
TK2ENSG00000166548.11220.75020416.43200-0.915705.221404.16600HepG2CNOT7
TK2ENSG00000166548.11388.60350253.519000.616103.675602.89400HepG2CPSF6
TK2ENSG00000166548.11423.66070326.149100.377302.320401.67030HepG2DNAJC21
TK2ENSG00000166548.11488.67850323.246100.596206.475305.53630HepG2DNAJC2
TK2ENSG00000166548.11656.27550487.112800.429902.563501.99320HepG2EIF2S1
TK2ENSG00000166548.11757.58050524.178800.531202.849802.15270HepG2EIF4B
TK2ENSG00000166548.111013.27820729.480100.474006.283005.11180HepG2EIF4G1
TK2ENSG00000166548.11712.48190441.580500.690104.706803.72410HepG2FIP1L1
TK2ENSG00000166548.11485.67230336.655300.528603.529902.64680HepG2FUBP3
TK2ENSG00000166548.11826.76150503.856700.714406.242405.26240HepG2G3BP1
TK2ENSG00000166548.11705.70890531.165100.409804.092802.91920HepG2HDGF
TK2ENSG00000166548.11563.54720329.273400.775207.187606.21890HepG2HNRNPA1
TK2ENSG00000166548.11518.59570366.248200.501703.174402.43800HepG2HNRNPC
TK2ENSG00000166548.11498.03850363.827400.452903.870103.16400HepG2HNRNPU
TK2ENSG00000166548.11723.85950515.171900.490602.685801.70050HepG2KHSRP
TK2ENSG00000166548.11479.84910357.371100.425102.541001.76400HepG2MSI2
TK2ENSG00000166548.11803.23620559.305600.522103.627802.90630HepG2NCBP2
TK2ENSG00000166548.11356.63420243.179000.552302.919902.15110HepG2NSUN2
TK2ENSG00000166548.11756.78050538.863200.489905.694804.87330HepG2PCBP1
TK2ENSG00000166548.11842.17730548.345400.618908.690507.83140HepG2PTBP1
TK2ENSG00000166548.11556.89330742.40400-0.414803.171202.45270HepG2PUM2
TK2ENSG00000166548.11778.37270566.740100.457705.357504.55110HepG2PUS1
TK2ENSG00000166548.11918.16030593.803600.628707.925406.95170HepG2QKI
TK2ENSG00000166548.11805.93680590.321200.449103.101602.04930HepG2RBM27
TK2ENSG00000166548.11348.79630580.89360-0.735904.532703.65900HepG2SF3A3
TK2ENSG00000166548.11545.69380377.856600.530205.416004.56750HepG2SMN1
TK2ENSG00000166548.11506.96150302.015500.747203.942203.00180HepG2SNRNP70
TK2ENSG00000166548.111197.59580808.386400.566909.912609.12380HepG2SRFBP1
TK2ENSG00000166548.11538.05790407.042200.402502.992702.27340HepG2SRSF7
TK2ENSG00000166548.11582.35080484.782200.264501.882501.41120HepG2SRSF9
TK2ENSG00000166548.11799.19190535.645100.577206.926606.10930HepG2TAF15
TK2ENSG00000166548.11470.45000356.684700.399302.950702.37280HepG2TRIM56
TK2ENSG00000166548.11559.66380275.232901.0238010.477409.00670HepG2UCHL5
TK2ENSG00000166548.11639.86680426.609200.584802.999701.95460HepG2UPF2
TK2ENSG00000166548.11335.63680497.37200-0.567404.674103.92750HepG2UTP3
TK2ENSG00000166548.11409.02820294.689400.472903.535402.79030HepG2ZC3H8
TK2ENSG00000166548.11103.36360190.84090-0.884604.649703.94760K562AGGF1
TK2ENSG00000166548.11127.85090198.57530-0.635202.770502.11670K562AKAP8L
TK2ENSG00000166548.11113.1147051.892001.124103.837302.81050K562BOP1
TK2ENSG00000166548.1179.50820183.87410-1.209507.239305.25650K562CIRBP
TK2ENSG00000166548.11128.7666055.178301.222505.241304.16950K562CPSF6
TK2ENSG00000166548.11202.37620115.534600.808604.399503.04370K562DDX3X
TK2ENSG00000166548.11201.23820132.556200.602202.905402.23780K562DDX47
TK2ENSG00000166548.11191.95530126.902300.597002.793901.57880K562EIF2S1
TK2ENSG00000166548.11354.61330138.647601.3547016.0579014.53860K562EIF2S2
TK2ENSG00000166548.11368.38240218.166400.755705.705304.37860K562EIF4G2
TK2ENSG00000166548.11113.7210056.138201.018303.420402.46630K562FMR1
TK2ENSG00000166548.1199.7839047.580301.068303.392702.37320K562FTO
TK2ENSG00000166548.11284.03010184.791300.620003.198402.38800K562GRSF1
TK2ENSG00000166548.1183.82900171.33820-1.031304.796703.12920K562HNRNPK
TK2ENSG00000166548.11261.93560111.155801.236508.873607.46330K562HSPD1
TK2ENSG00000166548.1195.7809044.980401.090302.890801.93270K562KRR1
TK2ENSG00000166548.11111.1227051.424201.111503.998602.93400K562METAP2
TK2ENSG00000166548.11181.19410107.294200.755903.633802.71660K562MTPAP
TK2ENSG00000166548.11366.42310248.062400.562703.251802.21190K562PUM2
TK2ENSG00000166548.11206.52950100.950501.032604.879503.79290K562RPS19
TK2ENSG00000166548.11240.48460126.392700.927906.639405.58080K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TK2 is not available on ENCORE database.






No RBPs affect the alternative splcing events of TK2 on ENCORE database.





The Knockdown/knockout RNA-Seq assay for TK2 is not avaliable on ENCORE database.