SRA1

General Information

Gene Name       : SRA1
Gene ID             : ENSG00000213523.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SRA1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SRA1ENSG00000213523.1032.2238.7435.48ENCSR000AEF
HepG2SRA1ENSG00000213523.1020.0717.9219.00ENCSR985KAT
K562SRA1ENSG00000213523.1035.7429.3132.52ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq SRA1-BGKcLV33-K562SRA1K562Released   CRISPRKD% = 53.3,50.8
knockdown followed by RNA-seq SRA1-BGKcLV33-K562ENCSR033MIVSRA1K562ReleasedENCSR271ZAB   CRISPRKD% = 82.7,80.6






  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
SRA1ENCAB874LTSA300-743A1BGKcLV33-73, Released, ENCODE4


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
SRA1K562CRISPRBGKcLV33-69,BGKcLV33-70BGKcLV33-1,BGKcLV33-253.3,50.8ReleasedENCODE4
SRA1K562CRISPRENCSR033MIVENCSR271ZABSRA1-BGKcLV33-73,SRA1-BGKcLV33-74NT-BGKcLV33-1,NT-BGKcLV33-282.7,80.6ReleasedENCODE4
SRA1HepG2CRISPRBGHcLV31-69,BGHcLV31-70BGHcLV31-1,BGHcLV31-2NO CLEAR BAND,NotSatisfiedENCODE4


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
SRA1Product_ID: A300-743A
Lot_ID: 1
Source: Bethyl Labs
Target Name: SRA1-human		 SRA1-K562-CRISPR-A300-743A.png<br>Caption: Western blot following CRISPR against SRA1 in K562 whole cell lysate using SRA1 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against SRA1. SRA1 protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.








RNA Targets

  • eCLIP assay for SRA1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SRA1 RNA is bound by 2 proteins.  







eCLIP assay for SRA1 is not avaliable on ENCORE database.





2 proteins are bound to SRA1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5139930233139930305-3'-UTR,CDS,intron-Distal,intron-Proximal4.463537.71026K562PABPC4
chr5139930166139930233-3'-UTR,intron-Distal,intron-Proximal3.732255.82813K562PABPC4
chr5139936845139936963-CDS,intron-Distal,intron-Proximal3.296203.39477K562BUD13
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SRA1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SRA1 is not available on ENCORE database.

  • 63 RBPs can affect the levels of SRA1.  








The Knockdown/knockout RNA-Seq assay for SRA1 is not available on ENCORE database.





63 RBPs can affect the gene expression of SRA1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SRA1ENSG00000213523.5389.91710206.904700.9141010.095609.08420HepG2ACO1
SRA1ENSG00000213523.5627.58030293.781201.095009.938708.99680HepG2AKAP1
SRA1ENSG00000213523.5449.43580243.073800.886606.961305.74030HepG2ASCC1
SRA1ENSG00000213523.5318.74530197.097200.693404.239903.51670HepG2BOP1
SRA1ENSG00000213523.5289.95830206.805400.487502.939902.25890HepG2CKAP4
SRA1ENSG00000213523.5494.76830313.533500.658006.614605.70210HepG2CELF1
SRA1ENSG00000213523.5248.32580157.866000.653403.244902.51380HepG2DDX21
SRA1ENSG00000213523.5521.05660281.408400.888707.295106.32370HepG2DDX3X
SRA1ENSG00000213523.5501.59530241.763401.052808.926707.88170HepG2DDX6
SRA1ENSG00000213523.5237.23240169.332500.486302.599601.96410HepG2DNAJC2
SRA1ENSG00000213523.5264.59260169.058500.646102.365901.51110HepG2EEF2
SRA1ENSG00000213523.5407.79980256.799900.667101.980701.43690HepG2EIF4A3
SRA1ENSG00000213523.5399.37620250.056200.675403.280002.53350HepG2EIF4B
SRA1ENSG00000213523.5387.42230202.134700.938507.974306.56700HepG2EWSR1
SRA1ENSG00000213523.580.10580181.24660-1.178003.050201.98300HepG2FTO
SRA1ENSG00000213523.5324.80460188.958300.781404.086902.73930HepG2FUS
SRA1ENSG00000213523.5371.18090259.140700.518302.576601.90930HepG2FXR1
SRA1ENSG00000213523.5338.93540240.369800.495702.310801.70010HepG2G3BP1
SRA1ENSG00000213523.5259.43360172.483100.588802.765002.11830HepG2HNRNPA1
SRA1ENSG00000213523.5294.10970191.853800.616203.098202.37000HepG2HNRNPC
SRA1ENSG00000213523.5336.51460243.445700.467002.132001.51370HepG2HNRNPK
SRA1ENSG00000213523.5384.87240307.070000.325701.911001.33780HepG2HNRNPL
SRA1ENSG00000213523.5387.12970244.323100.663904.022503.22190HepG2IGF2BP2
SRA1ENSG00000213523.5457.90820290.323100.657303.719702.75640HepG2LARP4
SRA1ENSG00000213523.5298.16830153.804300.954904.870803.36710HepG2LARP7
SRA1ENSG00000213523.5568.94730259.231301.1340011.6997010.38300HepG2MAGOH
SRA1ENSG00000213523.5488.29060260.675700.905406.732105.78200HepG2MATR3
SRA1ENSG00000213523.5303.78880210.007200.532502.715601.91330HepG2MSI2
SRA1ENSG00000213523.5444.98120266.810700.737804.889404.06010HepG2NCBP2
SRA1ENSG00000213523.593.40230173.57590-0.894003.587702.73590HepG2NSUN2
SRA1ENSG00000213523.5279.93590188.649200.569303.420002.48770HepG2PARN
SRA1ENSG00000213523.5175.05130245.65050-0.488802.444701.71260HepG2PRPF4
SRA1ENSG00000213523.5407.94380273.023400.579204.241403.59580HepG2PTBP1
SRA1ENSG00000213523.5264.17510133.539100.984104.752503.97050HepG2RPS19
SRA1ENSG00000213523.5366.32960171.032001.098804.124303.15530HepG2RPS2
SRA1ENSG00000213523.5553.98480220.612801.328207.195306.07280HepG2SF3A3
SRA1ENSG00000213523.5215.20050305.98000-0.507803.048302.31630HepG2SLBP
SRA1ENSG00000213523.5269.03390197.930800.442702.404501.79900HepG2SMN1
SRA1ENSG00000213523.5343.93220176.080300.965806.402704.89840HepG2SMNDC1
SRA1ENSG00000213523.5445.46890296.695800.586204.707204.13220HepG2SRSF1
SRA1ENSG00000213523.5574.68020358.316500.681408.407707.42200HepG2SUCLG1
SRA1ENSG00000213523.5465.68480185.196001.3302011.0028010.12000HepG2TIAL1
SRA1ENSG00000213523.5267.83110195.651000.452902.437901.77530HepG2UPF1
SRA1ENSG00000213523.5448.33540188.891501.2469017.3364016.02820HepG2UTP3
SRA1ENSG00000213523.5340.27110189.827700.841904.773903.40230HepG2XRCC6
SRA1ENSG00000213523.5356.32150215.177000.727606.777906.02050HepG2ZNF622
SRA1ENSG00000213523.51702.94430903.803700.9138015.1888013.96510K562AQR
SRA1ENSG00000213523.5944.397001246.68180-0.400603.165301.59560K562DDX19B
SRA1ENSG00000213523.5899.86490650.817500.467405.552604.67700K562DDX47
SRA1ENSG00000213523.5659.01350517.154800.349602.737701.44170K562DDX6
SRA1ENSG00000213523.5285.08600399.13410-0.485502.668001.36600K562DHX30
SRA1ENSG00000213523.51397.036701189.742800.231602.063701.31880K562DKC1
SRA1ENSG00000213523.5269.38440383.38920-0.509102.850801.48370K562DNAJC21
SRA1ENSG00000213523.5585.43010375.482500.640704.879503.65160K562EFTUD2
SRA1ENSG00000213523.5807.85720532.906200.600105.866904.67950K562EIF4A3
SRA1ENSG00000213523.5647.30880479.903800.431603.793902.40910K562EIF4B
SRA1ENSG00000213523.5684.44220492.942100.473403.585402.60980K562FIP1L1
SRA1ENSG00000213523.5683.30980554.198800.302002.146501.60140K562FXR1
SRA1ENSG00000213523.51118.54250881.025300.344302.340501.64290K562GRSF1
SRA1ENSG00000213523.5665.94050441.540400.592705.081704.29430K562HNRNPC
SRA1ENSG00000213523.5685.86830405.483000.758203.172602.17070K562HNRNPM
SRA1ENSG00000213523.51088.26410668.281300.703408.090606.74620K562HSPD1
SRA1ENSG00000213523.5822.17110536.018100.617104.511403.07150K562IGF2BP2
SRA1ENSG00000213523.5713.35010532.149100.422703.370902.00570K562NCBP2
SRA1ENSG00000213523.5470.31160623.79960-0.407502.214301.47130K562PCBP3
SRA1ENSG00000213523.5853.62630559.631600.609005.365604.16210K562PPIG
SRA1ENSG00000213523.5713.43290365.389600.9652010.292408.84010K562PRPF8
SRA1ENSG00000213523.5776.23710547.068400.504704.843603.98820K562PTBP1
SRA1ENSG00000213523.5686.23580372.134300.882807.540106.17700K562RPS19
SRA1ENSG00000213523.5278.97160392.68080-0.493202.811101.53750K562SLBP
SRA1ENSG00000213523.5759.78800542.744900.485203.676002.85620K562TARDBP
SRA1ENSG00000213523.5667.71890523.556200.350802.422301.66200K562TIA1
SRA1ENSG00000213523.5792.62230645.207300.296802.531401.84300K562UPF1
SRA1ENSG00000213523.5788.466701018.15400-0.368802.879501.99590K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SRA1 is not available on ENCORE database.





9 RBPs can affect the splicing of SRA1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESRA1ENSG00000213523.5chr5-139931566139931769139930645139930754139936731139936917-0.194000.000020.00093excludedK562SRSF1
SESRA1ENSG00000213523.5chr5-1399315661399317691399306451399307541399367311399369170.138000.003490.07282includedHepG2HNRNPK
SESRA1ENSG00000213523.5chr5-139931566139931769139930645139930754139936731139936917-0.224000.001160.02877excludedHepG2SRSF1
A3SSSRA1ENSG00000213523.5chr5-1399306451399308481399306451399307541399315661399317690.122000.000000.00000longerK562AQR
A3SSSRA1ENSG00000213523.5chr5-139930645139931769139930645139930754139936731139937031-0.259000.000530.04858shorterK562SRSF1
RISRA1ENSG00000213523.5chr5-1399306451399317691399306451399307541399315661399317690.051000.008020.04626includedK562PUS1
RISRA1ENSG00000213523.5chr5-1399306451399317691399306451399307541399315661399317690.146000.003370.03968includedHepG2PRPF8
RISRA1ENSG00000213523.5chr5-1399306451399317691399306451399307541399315661399317690.118000.003640.04180includedK562PRPF8
RISRA1ENSG00000213523.5chr5-1399306451399317691399306451399307541399315661399317690.188000.005010.08661includedHepG2FTO
RISRA1ENSG00000213523.5chr5-1399306451399317691399306451399307541399315661399317690.142000.001900.06847includedK562SUPV3L1
RISRA1ENSG00000213523.5chr5-1399306451399317691399306451399307541399315661399317690.069000.010070.08921includedK562UTP18
RISRA1ENSG00000213523.5chr5-1399306451399317691399306451399307541399315661399317690.153000.000290.00441includedK562EFTUD2
RISRA1ENSG00000213523.5chr5-1399306451399317691399306451399307541399315661399317690.219000.000000.00000includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SRA1 is not avaliable on ENCORE database.