RPP40

General Information

Gene Name       : RPP40
Gene ID             : ENSG00000124787.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: RPP40)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RPP40ENSG00000124787.138.2414.6111.43ENCSR000AEF
HepG2RPP40ENSG00000124787.1324.4440.8532.65ENCSR985KAT
K562RPP40ENSG00000124787.1334.8134.4234.62ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RPP40 is not avaliable on ENCORE database.



Proteins bound to RNA
  • RPP40 RNA is bound by 4 proteins.  







eCLIP assay for RPP40 is not avaliable on ENCORE database.





4 proteins are bound to RPP40 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr650041385004200-CDS,intron-Distal4.046183.02250K562YBX3
chr650008325000890-CDS,intron-Distal,intron-Proximal5.5693812.58557HepG2DROSHA
chr650010975001183-intron-Distal4.806463.80336K562DDX6
chr650011245001246-intron-Distal,intron-Proximal6.4516318.41449HepG2DROSHA
chr650010045001057-intron-Distal3.782923.27618K562RBFOX2
chr650011305001277-intron-Distal,intron-Proximal6.5322020.60802HepG2RBFOX2
chr650021175002215-intron-Distal4.933865.52571HepG2RBFOX2
chr650009685001063-intron-Distal7.8483632.34342K562DROSHA
chr650022835002332-intron-Distal,intron-Proximal4.305544.50422HepG2DROSHA
chr650009705001054-intron-Distal5.506436.37383K562DDX6
chr650017185001758-intron-Distal4.684386.09817HepG2DROSHA
chr650020345002187-intron-Distal5.9354417.80660HepG2DROSHA
chr650010925001207-intron-Distal5.6978111.74611K562DROSHA
chr650009485001004-intron-Distal,intron-Proximal5.7139613.43272HepG2RBFOX2
chr650010165001063-intron-Distal5.177456.07369HepG2RBFOX2
chr650009235001004-intron-Distal,intron-Proximal6.6915825.24738HepG2DROSHA
chr650010045001066-intron-Distal7.2424335.60606HepG2DROSHA
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RPP40 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RPP40 is not available on ENCORE database.

  • 65 RBPs can affect the levels of RPP40.  








The Knockdown/knockout RNA-Seq assay for RPP40 is not available on ENCORE database.





65 RBPs can affect the gene expression of RPP40 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RPP40ENSG00000124787.9247.16470344.91120-0.480802.968402.26140HepG2AUH
RPP40ENSG00000124787.9374.61650283.910500.399901.911601.40620HepG2BOP1
RPP40ENSG00000124787.9201.25090304.40020-0.597002.568601.63460HepG2CCAR1
RPP40ENSG00000124787.9327.06710234.565000.479503.142502.44330HepG2CKAP4
RPP40ENSG00000124787.998.81220208.73200-1.078904.886203.86470HepG2CNOT7
RPP40ENSG00000124787.9157.51340260.64360-0.726603.752402.96450HepG2CPSF6
RPP40ENSG00000124787.9309.27970206.205000.584702.732201.45070HepG2DDX27
RPP40ENSG00000124787.9373.27850232.167600.685004.673603.01570HepG2DDX47
RPP40ENSG00000124787.9337.44920220.355900.614703.081802.27320HepG2DDX55
RPP40ENSG00000124787.9297.20880174.685400.766604.579003.14950HepG2EFTUD2
RPP40ENSG00000124787.9108.34070289.85370-1.4197010.977009.84320HepG2EIF2S1
RPP40ENSG00000124787.9568.78270299.149200.9269012.1285010.62030HepG2EIF4G1
RPP40ENSG00000124787.9163.70720286.57260-0.807805.053703.97260HepG2EIF4G2
RPP40ENSG00000124787.9362.77040229.264000.661904.626003.55140HepG2EWSR1
RPP40ENSG00000124787.994.93630210.20720-1.146807.126205.90160HepG2FUBP3
RPP40ENSG00000124787.9135.75870299.80960-1.143008.233807.11610HepG2G3BP1
RPP40ENSG00000124787.9123.35270205.51700-0.736503.153702.06380HepG2GNB2L1
RPP40ENSG00000124787.9201.12440276.26250-0.458002.697602.03180HepG2HNRNPL
RPP40ENSG00000124787.9206.96760305.20770-0.560402.306801.64410HepG2IGF2BP1
RPP40ENSG00000124787.9123.51380199.48950-0.691603.922803.06560HepG2ILF2
RPP40ENSG00000124787.9331.67580190.730600.798103.622402.59700HepG2PABPC1
RPP40ENSG00000124787.9411.31540275.272200.579304.720703.96310HepG2PCBP1
RPP40ENSG00000124787.9335.32620238.663800.490502.834002.05340HepG2PRPF4
RPP40ENSG00000124787.9319.27530170.039900.908805.942804.80870HepG2PRPF8
RPP40ENSG00000124787.9397.50960304.695400.383502.352301.79690HepG2PUM1
RPP40ENSG00000124787.9219.20550304.48180-0.474102.546301.90240HepG2PUM2
RPP40ENSG00000124787.9535.00400207.560701.365909.857008.58150HepG2RAVER1
RPP40ENSG00000124787.9481.48440330.991800.540604.280903.67280HepG2RBM22
RPP40ENSG00000124787.9354.97100168.209801.077307.779206.54430HepG2RRP9
RPP40ENSG00000124787.9366.72490240.477200.608702.283101.66970HepG2SF3A3
RPP40ENSG00000124787.9517.54580279.080700.890908.190407.03680HepG2SF3B1
RPP40ENSG00000124787.9432.93400291.617500.570004.375003.65720HepG2SF3B4
RPP40ENSG00000124787.9708.89880310.527201.190804.051003.09690HepG2SNRNP70
RPP40ENSG00000124787.9446.62520304.387900.553104.312203.75360HepG2SRSF1
RPP40ENSG00000124787.9220.34120324.57570-0.558803.839103.25740HepG2SSB
RPP40ENSG00000124787.9300.35180193.982100.630602.507801.36370HepG2SUB1
RPP40ENSG00000124787.9230.20960147.049600.646502.892401.87480HepG2TFIP11
RPP40ENSG00000124787.9142.17210191.46340-0.429401.852301.37300HepG2TRIM56
RPP40ENSG00000124787.9188.71990129.602900.542002.221801.54180HepG2UCHL5
RPP40ENSG00000124787.9388.25070205.901600.914908.238807.29420HepG2UTP3
RPP40ENSG00000124787.9312.68420207.446800.591902.747601.45620HepG2ZRANB2
RPP40ENSG00000124787.9315.29170237.559900.408301.880901.33820K562AKAP8L
RPP40ENSG00000124787.9642.81310432.469900.571702.471001.30410K562APOBEC3C
RPP40ENSG00000124787.9187.42220434.80460-1.2141011.1825010.11990K562AQR
RPP40ENSG00000124787.9146.64220253.24300-0.788204.104103.03980K562BOP1
RPP40ENSG00000124787.9178.19930269.27770-0.595603.139902.30330K562CPSF6
RPP40ENSG00000124787.91105.93770387.372801.5134023.0296021.33800K562DDX47
RPP40ENSG00000124787.9380.11860255.634600.572304.253103.13350K562DKC1
RPP40ENSG00000124787.9248.89620354.33760-0.509603.306302.53180K562EIF2S2
RPP40ENSG00000124787.9332.32440129.914901.354908.233706.46060K562EIF3A
RPP40ENSG00000124787.9340.90790201.004000.762103.449802.56690K562EIF3G
RPP40ENSG00000124787.9169.93580273.96880-0.689003.610202.62800K562FMR1
RPP40ENSG00000124787.9342.14550203.507800.749405.786204.95780K562FXR1
RPP40ENSG00000124787.9612.50650472.212500.375202.268901.58120K562GRSF1
RPP40ENSG00000124787.9139.82200207.64420-0.570502.268601.72060K562HNRNPC
RPP40ENSG00000124787.9369.75060210.586100.812004.999203.28380K562HNRNPK
RPP40ENSG00000124787.9384.49210263.741600.543702.839401.89510K562HNRNPM
RPP40ENSG00000124787.9577.94640434.714100.410802.466601.71140K562HSPD1
RPP40ENSG00000124787.9296.53780197.145500.588902.751001.77330K562PCBP2
RPP40ENSG00000124787.9137.02760306.83280-1.163008.415806.96780K562PCBP3
RPP40ENSG00000124787.9153.26950235.34430-0.618703.129802.27470K562POLR2G
RPP40ENSG00000124787.9454.05990203.564001.1573010.998109.48940K562PRPF8
RPP40ENSG00000124787.9841.66490534.747400.654306.485405.23640K562PUF60
RPP40ENSG00000124787.9544.89510207.382201.3936015.4255013.47360K562RPS19
RPP40ENSG00000124787.9431.24730259.784900.731103.538901.74420K562RPS3A
RPP40ENSG00000124787.9343.63990209.719200.712304.708503.28970K562SAFB
RPP40ENSG00000124787.9278.60710176.022600.662404.282803.21270K562SF3B4
RPP40ENSG00000124787.9445.82650236.066000.917207.360006.00540K562SYNCRIP
RPP40ENSG00000124787.9198.22740315.24110-0.669305.177404.22840K562UPF1
RPP40ENSG00000124787.9441.69600280.491100.655006.511905.26590K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RPP40 is not available on ENCORE database.





11 RBPs can affect the splicing of RPP40 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERPP40ENSG00000124787.9chr6-499894949990754996455499665450000425000138-0.288000.000230.00990excludedK562AKAP8L
SERPP40ENSG00000124787.9chr6-5000796500086550000425000138500233450024790.153000.000010.00157includedHepG2QKI
SERPP40ENSG00000124787.9chr6-499894949990754996455499665450000425000138-0.092000.000360.00587excludedHepG2U2AF2
SERPP40ENSG00000124787.9chr6-499894949990754996455499665450000425000138-0.330000.000010.00038excludedK562PUS1
SERPP40ENSG00000124787.9chr6-5000796500086550000425000138500233450024790.088000.001260.06621includedHepG2NCBP2
SERPP40ENSG00000124787.9chr6-499894949990754996455499665450000425000138-0.497000.000000.00000excludedK562U2AF1
SERPP40ENSG00000124787.9chr6-500079650008655000042500013850023345002479-0.102000.005380.08590excludedK562U2AF1
SERPP40ENSG00000124787.9chr6-499894949990754996455499665450000425000138-0.302000.000200.01007excludedK562UTP18
SERPP40ENSG00000124787.9chr6-499894949990754996455499665450000425000138-0.573000.000000.00000excludedK562U2AF2
SERPP40ENSG00000124787.9chr6-499894949990754996455499665450000425000138-0.292000.000070.00348excludedK562RBM15
SERPP40ENSG00000124787.9chr6-499894949990754996455499665450000425000138-0.334000.000020.00106excludedK562AGGF1
SERPP40ENSG00000124787.9chr6-5000796500086550000425000138500233450024790.146000.000150.03695includedHepG2DDX55
SERPP40ENSG00000124787.9chr6-4998949499907549964554996654500004250001380.218000.000870.03604includedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RPP40 is not avaliable on ENCORE database.