RNF146

General Information

Gene Name       : RNF146
Gene ID             : ENSG00000118518.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: RNF146)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RNF146ENSG00000118518.1515.7812.2814.03ENCSR000AEF
HepG2RNF146ENSG00000118518.1514.3219.2616.79ENCSR985KAT
K562RNF146ENSG00000118518.1510.5011.7811.14ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RNF146 is not avaliable on ENCORE database.



Proteins bound to RNA
  • RNF146 RNA is bound by 10 proteins.  







eCLIP assay for RNF146 is not avaliable on ENCORE database.





10 proteins are bound to RNF146 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6127603386127603513+3'-UTR,intron-Distal,intron-Proximal3.110344.81700HepG2U2AF2
chr6127607177127607221+3'-UTR,CDS,intron-Distal,intron-Proximal3.410786.96989HepG2U2AF2
chr6127607280127607355+3'-UTR,CDS,intron-Distal,intron-Proximal4.238343.89565K562PRPF8
chr6127607887127608114+3'-UTR,CDS3.204285.18023HepG2GRWD1
chr6127608078127608142+3'-UTR,CDS4.523403.45943HepG2BCLAF1
chr6127588069127588177+5'-UTR,intron-Distal,intron-Proximal3.806463.90326K562DDX6
chr6127588017127588158+5'-UTR,intron-Proximal3.531889.84906HepG2NCBP2
chr6127588057127588178+5'-UTR,intron-Distal,intron-Proximal3.582243.87906HepG2SRSF9
chr6127591171127591220+intron-Distal4.431733.20552HepG2KHSRP
chr6127606817127606893+intron-Distal3.691765.52268HepG2RBFOX2
chr6127601490127601634+intron-Distal,intron-Proximal3.237277.02852K562KHSRP
chr6127588946127588981+intron-Distal4.204804.31871HepG2HNRNPM
chr6127606949127606979+intron-Distal3.062553.29251K562KHSRP
chr6127606979127607044+intron-Distal3.815686.89441K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RNF146 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RNF146 is not available on ENCORE database.

  • 48 RBPs can affect the levels of RNF146.  








The Knockdown/knockout RNA-Seq assay for RNF146 is not available on ENCORE database.





48 RBPs can affect the gene expression of RNF146 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RNF146ENSG00000118518.11627.76690432.762100.536604.143002.85880HepG2AATF
RNF146ENSG00000118518.11706.47770568.321300.313802.714702.11250HepG2ACO1
RNF146ENSG00000118518.11287.51130521.19220-0.858202.488601.91780HepG2BOP1
RNF146ENSG00000118518.11438.85920557.90530-0.346302.363001.42610HepG2YBX3
RNF146ENSG00000118518.11533.46640887.96780-0.7351013.4524012.02350HepG2DAZAP1
RNF146ENSG00000118518.11428.93330558.68090-0.381302.616901.49220HepG2DDX1
RNF146ENSG00000118518.11635.84470467.195500.444503.351402.34080HepG2DDX24
RNF146ENSG00000118518.111006.25360724.337800.474203.389702.70620HepG2DDX3X
RNF146ENSG00000118518.111236.65650643.627400.942008.763007.57530HepG2EIF4B
RNF146ENSG00000118518.111623.428001066.092200.6066011.6745010.57940HepG2ETF1
RNF146ENSG00000118518.11749.23090555.340900.431903.446702.51240HepG2EWSR1
RNF146ENSG00000118518.11873.92580551.975700.662804.858903.86270HepG2FIP1L1
RNF146ENSG00000118518.11488.72150312.985200.642804.851103.82510HepG2FUBP3
RNF146ENSG00000118518.11816.28440618.702900.399702.373101.75400HepG2G3BP1
RNF146ENSG00000118518.11777.47950553.065500.491303.807303.06700HepG2HNRNPA1
RNF146ENSG00000118518.11283.45830380.82750-0.426002.293801.42930HepG2HNRNPM
RNF146ENSG00000118518.11488.67850628.88550-0.363901.977401.39780HepG2IGF2BP2
RNF146ENSG00000118518.11737.61620604.899500.286102.220801.45430HepG2PARN
RNF146ENSG00000118518.11706.11230577.645100.289602.268401.70820HepG2PCBP1
RNF146ENSG00000118518.11428.65200545.06780-0.346602.407301.71570HepG2PPIL4
RNF146ENSG00000118518.11602.70750431.359300.482503.067502.22110HepG2PRPF8
RNF146ENSG00000118518.11909.73390587.788600.630009.126608.24860HepG2PTBP1
RNF146ENSG00000118518.11486.38150840.52680-0.789209.554908.53850HepG2PUF60
RNF146ENSG00000118518.11934.34400578.870400.6906012.1898011.05390HepG2PUS1
RNF146ENSG00000118518.11886.88530636.561500.478304.820404.02960HepG2QKI
RNF146ENSG00000118518.11796.94770572.811900.476304.618103.54530HepG2RBM15
RNF146ENSG00000118518.111682.98310891.048900.9173018.7676017.66360HepG2RBM22
RNF146ENSG00000118518.11730.12600577.731100.337602.271101.65520HepG2RBM25
RNF146ENSG00000118518.11891.58140654.141400.446704.832104.15250HepG2NELFE
RNF146ENSG00000118518.11759.53960609.263700.318002.603102.00310HepG2RECQL
RNF146ENSG00000118518.11865.02320627.424100.463203.453702.70370HepG2RPLP0
RNF146ENSG00000118518.11757.92500595.570600.347702.293601.56070HepG2RPS2
RNF146ENSG00000118518.11566.22900426.710100.408002.161501.45810HepG2RRP9
RNF146ENSG00000118518.11379.16340544.22620-0.521405.154004.32330HepG2SAFB2
RNF146ENSG00000118518.11636.04090805.94590-0.341603.348702.58900HepG2SLBP
RNF146ENSG00000118518.111264.538901006.394500.329304.159303.58160HepG2SRFBP1
RNF146ENSG00000118518.11810.23010638.742700.343003.155502.65920HepG2SRSF1
RNF146ENSG00000118518.11670.93740519.659500.368503.399002.79990HepG2SRSF9
RNF146ENSG00000118518.11921.15270574.153700.681909.662108.71610HepG2TAF15
RNF146ENSG00000118518.11548.94690373.071200.557103.428302.32930HepG2TFIP11
RNF146ENSG00000118518.11694.06890527.540600.395703.096002.21760HepG2TIA1
RNF146ENSG00000118518.11464.23330599.12380-0.368002.949602.37190HepG2TRIM56
RNF146ENSG00000118518.11651.94620869.19990-0.414902.311801.55230HepG2UBE2L3
RNF146ENSG00000118518.11469.99960346.917600.438002.648101.84600K562EIF4A3
RNF146ENSG00000118518.11531.06130392.698700.435402.135001.52570K562G3BP2
RNF146ENSG00000118518.11199.17850317.05590-0.670703.472602.41830K562HNRNPM
RNF146ENSG00000118518.11327.86720487.70310-0.572903.202202.06990K562IGF2BP2
RNF146ENSG00000118518.11519.08830380.544700.447802.350701.58420K562PCBP3
RNF146ENSG00000118518.11386.74790291.899300.405802.319301.58610K562POLR2G
RNF146ENSG00000118518.11420.17580305.780200.458402.359501.66430K562PRPF8
RNF146ENSG00000118518.11363.86120498.13870-0.453203.256802.54210K562PTBP1
RNF146ENSG00000118518.11368.69310477.75170-0.373802.099201.37140K562RBM22
RNF146ENSG00000118518.11238.16970408.82870-0.779503.213102.29110K562SF3B4
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RNF146 is not available on ENCORE database.





20 RBPs can affect the splicing of RNF146 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERNF146ENSG00000118518.11chr6+1276071941276073221276013751276014851276077601276095070.687000.000000.00000includedK562SRSF1
SERNF146ENSG00000118518.11chr6+1276071941276073221276013751276014851276077601276080360.217000.000530.03701includedHepG2RBM22
SERNF146ENSG00000118518.11chr6+1276071941276073221276013751276014851276077601276095070.402000.000060.01510includedK562MATR3
SERNF146ENSG00000118518.11chr6+127607194127607322127601375127601485127607760127608036-0.322000.000010.00084excludedK562AKAP8L
SERNF146ENSG00000118518.11chr6+1276071941276073221276013751276014851276077601276080360.319000.000510.02292includedK562FXR1
SERNF146ENSG00000118518.11chr6+127607194127607322127601375127601485127607760127608036-0.430000.000000.00007excludedHepG2SRSF7
SERNF146ENSG00000118518.11chr6+1276071941276073221276013751276014851276077601276095070.439000.000490.07350includedHepG2TIA1
SERNF146ENSG00000118518.11chr6+127607194127607322127601375127601485127607760127608036-0.386000.000000.00000excludedK562PUS1
SERNF146ENSG00000118518.11chr6+1276071941276073221276013751276014851276077601276095070.295000.001450.05549includedHepG2MATR3
SERNF146ENSG00000118518.11chr6+127607194127607322127601375127601485127607760127609507-0.227000.001590.03285excludedK562U2AF1
SERNF146ENSG00000118518.11chr6+1276071941276073221276013751276014851276077601276095070.299000.000130.02137includedHepG2LARP4
SERNF146ENSG00000118518.11chr6+1276071941276073221276013751276014851276077601276095070.524000.000000.00000includedHepG2SRSF1
SERNF146ENSG00000118518.11chr6+1276071941276073221276013751276014851276077601276095070.403000.000000.00051includedHepG2PCBP1
SERNF146ENSG00000118518.11chr6+1276071941276073221276013751276014851276077601276095070.433000.000240.03794includedK562RBM22
SERNF146ENSG00000118518.11chr6+1276071941276073221276013751276014851276077601276095070.354000.000160.02296includedHepG2TAF15
SERNF146ENSG00000118518.11chr6+127607194127607322127601375127601485127607760127608036-0.350000.000000.00006excludedK562RBM15
SERNF146ENSG00000118518.11chr6+127607194127607322127601375127601485127607760127608036-0.347000.000010.00042excludedK562AGGF1
SERNF146ENSG00000118518.11chr6+1276071941276073221276013751276014851276077601276080360.438000.000000.00216includedK562NCBP2
SERNF146ENSG00000118518.11chr6+1276034311276035401276013751276014851276071941276073220.619000.002600.08767includedHepG2HNRNPU
SERNF146ENSG00000118518.11chr6+1276071941276073221276013751276014851276077601276095070.405000.000010.00119includedHepG2SRSF9
SERNF146ENSG00000118518.11chr6+1276071941276073221276013751276014851276077601276095070.473000.000010.00057includedK562PTBP1
A5SSRNF146ENSG00000118518.11chr6+127588027127588240127588027127588070127601375127601485-0.397000.000050.01999shorterHepG2FUBP3
A5SSRNF146ENSG00000118518.11chr6+1275880271275882401275880271275880701276013751276014850.331000.002180.07358longerK562PUS1
A5SSRNF146ENSG00000118518.11chr6+127588027127588189127588027127588070127601375127601485-0.277000.000040.00665shorterHepG2SRSF9
A5SSRNF146ENSG00000118518.11chr6+1275880271275882401275880271275880701276013751276014850.370000.000600.05270longerK562AGGF1
A5SSRNF146ENSG00000118518.11chr6+1275880271275881891275880271275880701276013751276014850.194000.000420.06861longerHepG2HNRNPU
A5SSRNF146ENSG00000118518.11chr6+127588027127588189127588027127588070127601375127601485-0.264000.000100.00915shorterHepG2SRSF1
MXERNF146ENSG00000118518.11chr6+127603431127603540127606352127606493127601375127601485127607194127607322-0.506000.006900.084362includedK562SRSF1
MXERNF146ENSG00000118518.11chr6+1276034311276035401276063521276064931276013751276014851276071941276073220.344000.003310.036001includedHepG2SFPQ
MXERNF146ENSG00000118518.11chr6+127603431127603540127606352127606493127601375127601485127607194127607322-0.487000.001830.073562includedK562TIA1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RNF146 is not avaliable on ENCORE database.