PON3

General Information

Gene Name       : PON3
Gene ID             : ENSG00000105852.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PON3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PON3ENSG00000105852.100.180.530.35ENCSR000AEF
HepG2PON3ENSG00000105852.1018.4429.5023.97ENCSR985KAT
K562PON3ENSG00000105852.100.000.000.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PON3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PON3 RNA is bound by 2 proteins.  







eCLIP assay for PON3 is not avaliable on ENCORE database.





2 proteins are bound to PON3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr79502356695023677-intron-Distal3.978834.78196HepG2PTBP1
chr79500969595009746-intron-Distal3.796253.04224HepG2SUGP2
chr79501487095014955-intron-Distal4.100093.04224HepG2SUGP2
chr79500760095007660-intron-Distal3.922023.04224HepG2SUGP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PON3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PON3 is not available on ENCORE database.

  • 67 RBPs can affect the levels of PON3.  








The Knockdown/knockout RNA-Seq assay for PON3 is not available on ENCORE database.





67 RBPs can affect the gene expression of PON3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PON3ENSG00000105852.6570.21370228.082401.3218024.8512023.44330HepG2ACO1
PON3ENSG00000105852.6997.41230403.000301.3073016.7202015.52540HepG2AKAP1
PON3ENSG00000105852.6237.57480145.659600.705703.433102.28060HepG2AKAP8
PON3ENSG00000105852.6555.05200333.461900.735005.756304.64520HepG2ASCC1
PON3ENSG00000105852.6654.27280387.448000.7558010.022008.85090HepG2AUH
PON3ENSG00000105852.6143.56290249.72200-0.798602.296201.47950HepG2BCLAF1
PON3ENSG00000105852.6255.34220179.146400.511202.213901.67330HepG2BOP1
PON3ENSG00000105852.6378.05520258.587100.547803.369502.52900HepG2CALR
PON3ENSG00000105852.6660.56890316.807601.0600011.8456010.35720HepG2CIRBP
PON3ENSG00000105852.6123.89680228.03730-0.880106.222505.29700HepG2CKAP4
PON3ENSG00000105852.6693.71940182.003801.9303021.7696019.66210HepG2CNOT7
PON3ENSG00000105852.6987.79750381.907901.3709035.9235034.14280HepG2CELF1
PON3ENSG00000105852.6914.31250386.071701.2437017.0578015.64530HepG2DDX3X
PON3ENSG00000105852.6284.14310162.243100.808405.096003.36980HepG2DDX47
PON3ENSG00000105852.6674.12900282.482101.2548014.2960012.71930HepG2DDX55
PON3ENSG00000105852.6610.09830331.577900.879607.259206.29980HepG2DDX6
PON3ENSG00000105852.6438.99560218.214201.0084011.6609010.47000HepG2DKC1
PON3ENSG00000105852.6376.07890245.019100.618004.748903.84900HepG2DNAJC21
PON3ENSG00000105852.6178.86270242.87660-0.441402.251601.65080HepG2DNAJC2
PON3ENSG00000105852.6574.39220318.819100.849207.271706.34450HepG2EIF2S1
PON3ENSG00000105852.6503.33650388.085100.375102.016001.31370HepG2EIF4G2
PON3ENSG00000105852.686.36000222.88130-1.3678010.416908.83250HepG2EWSR1
PON3ENSG00000105852.6237.88830152.174300.644503.500102.17010HepG2FAM120A
PON3ENSG00000105852.6406.33930201.600801.011106.778205.62930HepG2FIP1L1
PON3ENSG00000105852.6247.42300178.067700.474502.089201.39830HepG2FUBP3
PON3ENSG00000105852.6604.67710268.803601.1695010.386308.42760HepG2FUS
PON3ENSG00000105852.6656.91130283.679901.211308.081406.33650HepG2GNB2L1
PON3ENSG00000105852.6304.81390217.756100.485103.086102.05820HepG2HDGF
PON3ENSG00000105852.6567.84150377.394400.589306.034004.74800HepG2HNRNPA2B1
PON3ENSG00000105852.6427.53620275.156700.635704.107703.27530HepG2HNRNPC
PON3ENSG00000105852.6187.40330281.98420-0.589502.136401.49950HepG2HNRNPF
PON3ENSG00000105852.6250.90490374.06620-0.576204.634103.77830HepG2HNRNPL
PON3ENSG00000105852.6297.13160177.914300.739804.024503.28030HepG2HNRNPLL
PON3ENSG00000105852.6195.54120273.33700-0.483202.653502.05930HepG2HNRNPU
PON3ENSG00000105852.6194.47200277.67860-0.513902.052701.42290HepG2IGF2BP1
PON3ENSG00000105852.6282.89600177.415700.673002.933001.56310HepG2ILF3
PON3ENSG00000105852.6216.52900355.54880-0.715504.235603.42700HepG2MAGOH
PON3ENSG00000105852.6353.13030235.344300.585303.406001.63190HepG2MARK2
PON3ENSG00000105852.6386.13650178.178601.115706.036704.53220HepG2METAP2
PON3ENSG00000105852.6345.74050163.163301.083309.010007.62850HepG2MSI2
PON3ENSG00000105852.6586.07200365.989300.679204.992104.15170HepG2NCBP2
PON3ENSG00000105852.6171.24750407.19460-1.2496015.1102013.39710HepG2NOL12
PON3ENSG00000105852.6490.26730325.995300.588603.772002.93850HepG2PABPC4
PON3ENSG00000105852.6383.67250300.654100.351702.102101.56130HepG2PCBP1
PON3ENSG00000105852.6134.17640204.48130-0.607802.915402.12430HepG2PRPF4
PON3ENSG00000105852.6467.95460305.938800.613005.810305.07650HepG2PTBP1
PON3ENSG00000105852.6201.01250388.70290-0.951408.279107.32130HepG2PUF60
PON3ENSG00000105852.61014.93680412.625201.2984041.3369039.59570HepG2PUM1
PON3ENSG00000105852.6451.36370232.317400.9581012.1872011.05180HepG2PUS1
PON3ENSG00000105852.6139.37220243.41450-0.804505.468704.61540HepG2SAFB2
PON3ENSG00000105852.6256.12950166.263400.623302.887601.92740HepG2SERBP1
PON3ENSG00000105852.6499.99640283.855500.8167010.519209.39700HepG2SMN1
PON3ENSG00000105852.6602.74010419.943900.521205.126604.50370HepG2SRFBP1
PON3ENSG00000105852.6617.57900332.454100.8934012.1417011.30110HepG2SRSF1
PON3ENSG00000105852.6526.98090383.787300.457303.766303.05740HepG2SRSF5
PON3ENSG00000105852.6535.12620270.476700.984309.083108.18640HepG2SRSF9
PON3ENSG00000105852.6594.49030364.605000.705208.770007.95720HepG2SSB
PON3ENSG00000105852.6348.65160436.47200-0.324101.954101.41470HepG2SUCLG1
PON3ENSG00000105852.6365.10730281.248500.376401.890401.31730HepG2SUPV3L1
PON3ENSG00000105852.6516.74950298.847100.790008.606307.70660HepG2TAF15
PON3ENSG00000105852.6346.88440155.210401.160105.518004.05570HepG2TBRG4
PON3ENSG00000105852.6337.63900188.536600.840505.723104.36440HepG2TFIP11
PON3ENSG00000105852.6195.85960265.57160-0.439302.084701.63800HepG2TIAL1
PON3ENSG00000105852.6397.04520267.973900.567104.713304.01680HepG2TRIM56
PON3ENSG00000105852.6290.45530172.456900.752003.884603.14510HepG2U2AF1
PON3ENSG00000105852.6384.38530241.464300.670603.072901.73820HepG2XRCC5
PON3ENSG00000105852.6326.11820201.795600.692405.495704.60050HepG2ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PON3 is not available on ENCORE database.





8 RBPs can affect the splicing of PON3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPON3ENSG00000105852.6chr7-9500684495006988950014849500165095019465950195210.329000.000000.00000includedHepG2U2AF2
SEPON3ENSG00000105852.6chr7-949966739499680094993174949933759500148495001650-0.272000.003630.04101excludedHepG2U2AF2
SEPON3ENSG00000105852.6chr7-950194659501952195001484950016509502395595024048-0.238000.000000.00009excludedHepG2U2AF2
SEPON3ENSG00000105852.6chr7-9500684495006988950014849500165095019465950195210.134000.000350.02102includedHepG2SFPQ
SEPON3ENSG00000105852.6chr7-949966739499680094993174949933759500148495001650-0.171000.000100.02357excludedHepG2HNRNPA1
SEPON3ENSG00000105852.6chr7-9500684495006988950014849500165095019465950195210.288000.000000.00021includedHepG2MATR3
SEPON3ENSG00000105852.6chr7-9500684495006988950014849500165095019465950195210.203000.000010.00232includedHepG2RBFOX2
SEPON3ENSG00000105852.6chr7-9500684495006988950014849500165095019465950195210.162000.000240.03224includedHepG2TAF15
SEPON3ENSG00000105852.6chr7-949966739499680094993174949933759500148495001650-0.141000.000850.03764excludedHepG2HNRNPU
SEPON3ENSG00000105852.6chr7-9500684495006988950014849500165095019465950195210.154000.001400.07742includedHepG2SRSF9
MXEPON3ENSG00000105852.6chr7-9500148495001650950194659501952194993174949933759502395595024026-0.386000.000280.011492includedHepG2HNRNPU

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PON3 is not avaliable on ENCORE database.