PLCL1

General Information

Gene Name : PLCL1
Gene ID : ENSG00000115896.15
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: PLCL1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	PLCL1	ENSG00000115896.15	0.37	0.23	0.30	ENCSR000AEF
HepG2	PLCL1	ENSG00000115896.15	0.00	0.00	0.00	ENCSR985KAT
K562	PLCL1	ENSG00000115896.15	6.43	5.80	6.12	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for PLCL1 is not avaliable on ENCORE database.

Proteins bound to RNA

PLCL1 RNA is bound by 21 proteins.

eCLIP assay for PLCL1 is not avaliable on ENCORE database.

21 proteins are bound to PLCL1 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr2	199011930	199012020	+	3'-UTR	3.50958	4.38938	K562	TARDBP
chr2	199011900	199011999	+	3'-UTR	4.32609	22.48947	K562	EIF4G2
chr2	198949158	198949211	+	3'-UTR,CDS	4.02358	3.73926	K562	RBM15
chr2	198953643	198953700	+	3'-UTR,CDS	4.10633	3.02250	K562	YBX3
chr2	198669480	198669526	+	5'-UTR	3.89159	4.80676	K562	RBM15
chr2	198669921	198669994	+	CDS	3.21211	4.68262	K562	RBM15
chr2	198670016	198670062	+	CDS	3.97515	3.48187	K562	RBM15
chr2	198707159	198707215	+	intron-Distal	4.20955	3.90241	K562	MATR3
chr2	198828482	198828528	+	intron-Distal	3.19008	6.26546	K562	EXOSC5
chr2	198842005	198842080	+	intron-Distal	3.87235	3.33442	K562	HNRNPK
chr2	198794966	198795084	+	intron-Distal	3.96590	3.59673	K562	HNRNPL
chr2	198821874	198821928	+	intron-Distal	3.89675	3.33944	K562	MATR3
chr2	198894396	198894455	+	intron-Distal	3.47805	7.16876	K562	PTBP1
chr2	198761918	198761997	+	intron-Distal	4.06817	10.87923	K562	MATR3
chr2	198800141	198800213	+	intron-Distal	3.86838	6.09351	K562	ILF3
chr2	198696454	198696545	+	intron-Distal	3.13597	3.67498	K562	SAFB2
chr2	198784471	198784547	+	intron-Distal	4.02462	8.16945	K562	TARDBP
chr2	198706455	198706608	+	intron-Distal	3.13855	7.02852	K562	KHSRP
chr2	198684622	198684692	+	intron-Distal	4.02789	7.46094	K562	TARDBP
chr2	198675159	198675250	+	intron-Distal	3.00703	4.81794	K562	KHSRP
chr2	198678386	198678420	+	intron-Distal	3.19382	5.96041	K562	KHSRP
chr2	198714151	198714214	+	intron-Distal	4.20463	3.88340	K562	TARDBP
chr2	198709412	198709465	+	intron-Distal	3.02289	4.96160	K562	KHSRP
chr2	198786367	198786469	+	intron-Distal	4.33486	5.07945	K562	HNRNPL
chr2	198676598	198676654	+	intron-Distal	3.61619	4.17049	K562	TARDBP
chr2	198684634	198684694	+	intron-Distal	5.83141	11.47680	K562	EIF4G2
chr2	198670095	198670181	+	intron-Distal,intron-Proximal	4.02669	8.98893	K562	RBM15
chr2	198682064	198682154	+	intron-Distal	4.61037	25.42411	K562	TARDBP
chr2	198714767	198714832	+	intron-Distal	3.89046	10.12879	K562	AGGF1
chr2	198676542	198676597	+	intron-Distal	4.00837	4.29034	K562	U2AF2
chr2	198691215	198691356	+	intron-Distal	6.14357	32.52858	K562	QKI
chr2	198695916	198695970	+	intron-Distal	3.71673	3.10466	K562	SAFB2
chr2	198707792	198707840	+	intron-Distal	5.86863	11.61334	K562	PTBP1
chr2	198746242	198746311	+	intron-Distal	3.90993	6.16126	K562	TARDBP
chr2	198840123	198840315	+	intron-Distal	3.32360	3.56409	K562	MATR3
chr2	198970335	198970401	+	intron-Distal	4.11619	3.88340	K562	TARDBP
chr2	198799851	198799935	+	intron-Distal	4.93816	7.98841	K562	ILF3
chr2	198819467	198819598	+	intron-Distal	4.23356	5.56407	K562	QKI
chr2	198829079	198829133	+	intron-Distal	4.72052	6.41216	K562	EXOSC5
chr2	198694559	198694643	+	intron-Distal	3.73902	3.48705	K562	PPIL4
chr2	198714878	198714933	+	intron-Distal	3.87491	5.69449	K562	AGGF1
chr2	198743331	198743434	+	intron-Distal	4.81297	23.02519	K562	TARDBP
chr2	198696545	198696635	+	intron-Distal	4.09509	3.65589	K562	SAFB2
chr2	198863111	198863180	+	intron-Distal	4.99154	7.88729	K562	TARDBP
chr2	198844493	198844628	+	intron-Distal	3.89133	3.34601	K562	HNRNPK
chr2	198697784	198697881	+	intron-Distal	3.97727	7.64122	K562	SAFB2
chr2	198727068	198727130	+	intron-Distal	3.99747	3.82060	K562	KHDRBS1
chr2	198862933	198863066	+	intron-Distal	5.48734	24.99226	K562	TARDBP
chr2	198714832	198714878	+	intron-Distal	4.04203	8.84940	K562	AGGF1
chr2	198862900	198863035	+	intron-Distal	6.06974	12.95876	K562	EIF4G2
chr2	198761175	198761206	+	intron-Distal	4.63580	4.67693	K562	PTBP1
chr2	198720179	198720279	+	intron-Distal	4.13577	3.62025	K562	MATR3
chr2	198715102	198715232	+	intron-Distal	6.15941	21.29299	K562	TARDBP
chr2	198801052	198801109	+	intron-Distal	3.91564	6.85784	K562	ILF3
chr2	198784547	198784598	+	intron-Distal	4.82544	6.49093	K562	TARDBP
chr2	198672994	198673101	+	intron-Distal	3.35681	6.80241	K562	KHSRP
chr2	198876305	198876374	+	intron-Distal	4.06845	3.59909	K562	EXOSC5
chr2	198801492	198801528	+	intron-Distal	3.96658	3.81649	K562	ILF3
chr2	198707160	198707226	+	intron-Distal	4.07303	5.63677	K562	PTBP1
chr2	198694702	198694822	+	intron-Distal	4.88124	8.89716	K562	SAFB2
chr2	198711716	198711800	+	intron-Distal	4.85980	7.00934	K562	TARDBP
chr2	198876288	198876396	+	intron-Distal	4.22529	11.44618	K562	KHSRP
chr2	198774403	198774465	+	intron-Distal	4.65092	4.51377	K562	HNRNPM
chr2	198714782	198714851	+	intron-Distal	3.48386	3.04054	K562	GTF2F1
chr2	198821736	198821805	+	intron-Distal	4.62280	4.90095	K562	PTBP1
chr2	198707028	198707088	+	intron-Distal	5.22076	7.34317	K562	PTBP1
chr2	198698150	198698214	+	intron-Distal	3.59035	5.73368	K562	SAFB2
chr2	198720189	198720283	+	intron-Distal	4.62426	13.12839	K562	PTBP1
chr2	198694757	198694805	+	intron-Distal	3.99685	3.36385	K562	UCHL5
chr2	198841168	198841229	+	intron-Distal	3.33359	12.08663	K562	PTBP1
chr2	198694542	198694645	+	intron-Distal	3.23382	4.09989	K562	UCHL5
chr2	198714777	198714907	+	intron-Distal	6.76269	35.94192	K562	HNRNPL
chr2	198707309	198707451	+	intron-Distal	5.52959	18.60841	K562	PTBP1
chr2	198676369	198676431	+	intron-Distal	3.07840	5.22328	K562	KHSRP
chr2	198674194	198674260	+	intron-Distal	3.34359	4.46957	K562	TIA1
chr2	198674545	198674599	+	intron-Distal	4.18094	3.34609	K562	TARDBP
chr2	198714693	198714777	+	intron-Distal	4.06464	18.89908	K562	HNRNPL
chr2	198970334	198970387	+	intron-Distal	4.41070	3.89080	K562	EXOSC5
chr2	198840760	198840805	+	intron-Distal	4.51324	6.48743	K562	PTBP1
chr2	198762003	198762043	+	intron-Distal	4.29332	5.75812	K562	PTBP1
chr2	198829752	198829794	+	intron-Distal	4.56660	4.80399	K562	EXOSC5
chr2	198673169	198673217	+	intron-Distal	3.87868	3.42844	K562	KHSRP
chr2	198800869	198800956	+	intron-Distal	3.56771	5.60121	K562	ILF3
chr2	198782254	198782328	+	intron-Distal	4.03809	3.90026	K562	KHSRP
chr2	198707350	198707437	+	intron-Distal	4.80775	6.26399	K562	MATR3
chr2	198841014	198841075	+	intron-Distal	3.71309	5.29274	K562	PTBP1
chr2	198714699	198714771	+	intron-Distal	3.53041	4.12529	K562	GTF2F1
chr2	198716969	198717030	+	intron-Distal	3.22517	4.26200	K562	GTF2F1
chr2	198672863	198672984	+	intron-Distal	3.29415	5.83938	K562	KHSRP
chr2	198684576	198684634	+	intron-Distal	3.62068	4.00200	K562	EIF4G2
chr2	198782965	198783049	+	intron-Distal	4.13217	4.88815	K562	KHDRBS1
chr2	198828681	198828735	+	intron-Distal	4.56660	4.80399	K562	EXOSC5
chr2	198801109	198801155	+	intron-Distal	3.21396	3.37821	K562	ILF3
chr2	198700207	198700285	+	intron-Distal	4.44870	5.60468	K562	SAFB2
chr2	198761919	198761994	+	intron-Distal	6.63041	43.43601	K562	PTBP1
chr2	198864570	198864658	+	intron-Distal	4.34716	3.60944	K562	TARDBP
chr2	198698146	198698190	+	intron-Distal	3.52103	3.12941	K562	UCHL5
chr2	198800007	198800072	+	intron-Distal	3.74916	5.84562	K562	ILF3
chr2	198801970	198802088	+	intron-Distal	4.33126	8.98664	K562	KHSRP
chr2	198707023	198707081	+	intron-Distal	3.12792	4.82768	K562	MATR3
chr2	198800103	198800141	+	intron-Distal	3.78060	3.31709	K562	ILF3
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for PLCL1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for PLCL1 is not available on ENCORE database.
57 RBPs can affect the levels of PLCL1.

The Knockdown/knockout RNA-Seq assay for PLCL1 is not available on ENCORE database.

57 RBPs can affect the gene expression of PLCL1 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
PLCL1	ENSG00000115896.11	10.22840	0.00000	99999.99990	2.37100	1.87440	HepG2	AKAP1
PLCL1	ENSG00000115896.11	8.34730	0.47190	4.14460	1.90930	1.33680	HepG2	ZC3H8
PLCL1	ENSG00000115896.11	1209.07640	769.86620	0.65110	7.25260	5.30030	K562	ABCF1
PLCL1	ENSG00000115896.11	533.89540	839.63680	-0.65320	8.78070	7.84570	K562	AGGF1
PLCL1	ENSG00000115896.11	258.33520	817.74840	-1.66240	24.86450	23.29590	K562	AQR
PLCL1	ENSG00000115896.11	507.55500	403.65710	0.33030	2.25490	1.38840	K562	BCLAF1
PLCL1	ENSG00000115896.11	822.25700	600.74430	0.45270	3.16360	2.22990	K562	BOP1
PLCL1	ENSG00000115896.11	759.64170	536.29300	0.50220	3.49800	1.86680	K562	BUD13
PLCL1	ENSG00000115896.11	1246.27330	1003.39930	0.31260	2.83610	1.64290	K562	CCDC124
PLCL1	ENSG00000115896.11	1098.38660	1404.54850	-0.35470	3.45760	2.36500	K562	CELF1
PLCL1	ENSG00000115896.11	886.20710	556.75390	0.67050	7.92350	6.07360	K562	DDX3X
PLCL1	ENSG00000115896.11	275.50440	380.97560	-0.46760	2.45280	1.59460	K562	EFTUD2
PLCL1	ENSG00000115896.11	754.58280	557.92120	0.43550	4.04390	3.19880	K562	EIF2S2
PLCL1	ENSG00000115896.11	332.70620	580.15240	-0.80220	6.69250	5.46670	K562	EIF3G
PLCL1	ENSG00000115896.11	249.89560	581.63990	-1.21880	15.85990	13.77350	K562	EIF4A3
PLCL1	ENSG00000115896.11	374.49940	523.76920	-0.48400	3.19940	1.93780	K562	EIF4B
PLCL1	ENSG00000115896.11	574.15040	339.16610	0.75930	5.81000	3.39110	K562	FAM120A
PLCL1	ENSG00000115896.11	936.87150	649.89320	0.52750	4.57360	3.47150	K562	FMR1
PLCL1	ENSG00000115896.11	841.51680	550.81230	0.61130	2.57060	1.69220	K562	FTO
PLCL1	ENSG00000115896.11	254.70570	604.87580	-1.24780	18.69890	17.23520	K562	FXR1
PLCL1	ENSG00000115896.11	500.83670	656.16780	-0.38970	3.11140	1.89800	K562	GLRX3
PLCL1	ENSG00000115896.11	323.18600	743.37040	-1.20170	9.24450	7.84060	K562	GRSF1
PLCL1	ENSG00000115896.11	282.83080	519.96960	-0.87850	9.64470	7.77990	K562	HNRNPA1
PLCL1	ENSG00000115896.11	148.93650	439.56980	-1.56140	19.30210	17.80400	K562	HNRNPC
PLCL1	ENSG00000115896.11	400.51670	562.84000	-0.49090	3.67110	1.49990	K562	HNRNPH1
PLCL1	ENSG00000115896.11	687.62700	873.61140	-0.34540	2.49330	1.49620	K562	HNRNPL
PLCL1	ENSG00000115896.11	249.80920	455.27690	-0.86590	4.82050	3.55400	K562	HNRNPM
PLCL1	ENSG00000115896.11	398.53970	575.80620	-0.53090	4.82550	3.63630	K562	HNRNPU
PLCL1	ENSG00000115896.11	730.98910	927.18340	-0.34300	2.27720	1.53810	K562	KIF1C
PLCL1	ENSG00000115896.11	446.79790	861.79000	-0.94770	9.86910	8.21820	K562	MAGOH
PLCL1	ENSG00000115896.11	529.78940	860.10890	-0.69910	6.27090	4.79990	K562	MATR3
PLCL1	ENSG00000115896.11	427.39750	689.87460	-0.69080	9.35670	7.95980	K562	MTPAP
PLCL1	ENSG00000115896.11	945.71520	1249.45160	-0.40180	3.42070	1.74360	K562	NOL12
PLCL1	ENSG00000115896.11	474.75250	896.64380	-0.91740	4.71060	3.32340	K562	PABPN1
PLCL1	ENSG00000115896.11	594.99610	766.86040	-0.36610	2.30360	1.41490	K562	PCBP2
PLCL1	ENSG00000115896.11	262.17840	680.44420	-1.37590	18.21660	16.15570	K562	PCBP3
PLCL1	ENSG00000115896.11	209.84700	521.90910	-1.31450	18.10470	16.15600	K562	POLR2G
PLCL1	ENSG00000115896.11	165.34350	370.73390	-1.16490	9.72710	8.31480	K562	PRPF8
PLCL1	ENSG00000115896.11	620.17280	837.24990	-0.43300	3.14970	2.44600	K562	PTBP1
PLCL1	ENSG00000115896.11	693.40890	1246.26630	-0.84580	12.19190	10.46870	K562	PUF60
PLCL1	ENSG00000115896.11	598.79900	866.42690	-0.53300	4.12560	3.48210	K562	PUS1
PLCL1	ENSG00000115896.11	547.41810	844.22560	-0.62500	7.35760	6.42300	K562	RBM15
PLCL1	ENSG00000115896.11	614.22590	803.06420	-0.38670	2.41880	1.63580	K562	RBM22
PLCL1	ENSG00000115896.11	237.94750	465.08000	-0.96680	9.44610	7.50850	K562	SAFB
PLCL1	ENSG00000115896.11	433.35230	1000.27590	-1.20680	7.17770	4.68580	K562	SFPQ
PLCL1	ENSG00000115896.11	210.49610	316.70920	-0.58940	3.37120	1.96320	K562	SLBP
PLCL1	ENSG00000115896.11	372.68180	774.89830	-1.05610	21.33090	19.11680	K562	SRPK2
PLCL1	ENSG00000115896.11	337.10770	820.73440	-1.28370	15.44510	13.77250	K562	SRSF1
PLCL1	ENSG00000115896.11	435.06010	594.04130	-0.44930	3.39980	1.70830	K562	SRSF9
PLCL1	ENSG00000115896.11	824.23920	1087.37500	-0.39970	3.81750	2.06410	K562	SUCLG1
PLCL1	ENSG00000115896.11	265.98960	523.50890	-0.97680	11.69960	10.01770	K562	SYNCRIP
PLCL1	ENSG00000115896.11	428.17820	830.74370	-0.95620	8.11040	6.82090	K562	TARDBP
PLCL1	ENSG00000115896.11	173.55720	379.07410	-1.12710	9.22860	7.44660	K562	TIAL1
PLCL1	ENSG00000115896.11	836.02540	631.51270	0.40460	4.01760	2.48500	K562	TROVE2
PLCL1	ENSG00000115896.11	265.50030	379.88400	-0.51680	2.76440	1.74640	K562	UCHL5
PLCL1	ENSG00000115896.11	492.74580	695.44560	-0.49710	4.34540	3.23920	K562	WDR3
PLCL1	ENSG00000115896.11	526.03030	723.18140	-0.45920	5.18920	4.06210	K562	WDR43
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for PLCL1 is not available on ENCORE database.

1 RBPs can affect the splicing of PLCL1 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP	Bound by RBP
SE	PLCL1	ENSG00000115896.11	chr2	+	198866675	198866732			198669425	198670063	198948481	198950956	-0.81500	0.00047	0.06729	excluded	K562	LARP4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

PLCL1

General Information

Functions

Localization

Domains (AlphaFold: PLCL1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for PLCL1 is not avaliable on ENCORE database.

21 proteins are bound to PLCL1 RNA:

eCLIP assay for PLCL1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for PLCL1 is not available on ENCORE database.

57 RBPs can affect the gene expression of PLCL1 :

The Knockdown/knockout RNA-Seq assay for PLCL1 is not available on ENCORE database.

1 RBPs can affect the splicing of PLCL1 :

The Knockdown/knockout RNA-Seq assay for PLCL1 is not avaliable on ENCORE database.