NT5C

General Information

Gene Name       : NT5C
Gene ID             : ENSG00000125458.6
Essential Gene : No

Functions

Localization

Domains (AlphaFold: NT5C)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NT5CENSG00000125458.66.5416.5011.52ENCSR000AEF
HepG2NT5CENSG00000125458.641.8422.5632.20ENCSR985KAT
K562NT5CENSG00000125458.629.0420.8824.96ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NT5C is not avaliable on ENCORE database.



Proteins bound to RNA
  • NT5C RNA is bound by 18 proteins.  







eCLIP assay for NT5C is not avaliable on ENCORE database.





18 proteins are bound to NT5C RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr177312640673126527-3'-UTR,intron-Distal,intron-Proximal4.068173.08342HepG2AKAP1
chr177312649673126553-3'-UTR,intron-Distal,intron-Proximal3.958375.82560HepG2PABPN1
chr177312633973126373-3'-UTR,intron-Distal,intron-Proximal7.1900516.57425K562PABPC4
chr177312643873126492-3'-UTR,intron-Distal,intron-Proximal4.259093.99014HepG2PABPN1
chr177312684873126897-3'-UTR,CDS,intron-Distal,intron-Proximal5.596429.74663HepG2PPIG
chr177312636273126484-3'-UTR,intron-Distal,intron-Proximal4.171506.88182HepG2LARP4
chr177312641073126494-3'-UTR,intron-Distal,intron-Proximal3.701784.51056HepG2LSM11
chr177312639273126496-3'-UTR,intron-Distal,intron-Proximal4.700656.52213HepG2UPF1
chr177312693273126963-3'-UTR,CDS,intron-Distal,intron-Proximal4.173688.06490HepG2PPIG
chr177312775473127845-5'-UTR,CDS,intron-Distal,intron-Proximal4.000437.38342HepG2NCBP2
chr177312727373127343-5'-UTR,CDS,intron-Distal,intron-Proximal4.7041515.19414HepG2SRSF1
chr177312727873127337-5'-UTR,CDS,intron-Distal,intron-Proximal5.2086415.63780HepG2PPIG
chr177312729473127343-5'-UTR,CDS,intron-Distal,intron-Proximal3.316063.34231K562RBM15
chr177312738573127456-5'-UTR,intron-Distal,intron-Proximal5.022074.94135HepG2RBM5
chr177312737973127468-5'-UTR,intron-Distal,intron-Proximal4.7323334.23751HepG2SF3B4
chr177312737473127416-5'-UTR,CDS,intron-Distal,intron-Proximal5.4631819.58297HepG2SF3A3
chr177312771673127813-5'-UTR,CDS,intron-Distal,intron-Proximal3.851066.42088HepG2SRSF1
chr177312773473127819-5'-UTR,CDS,intron-Distal,intron-Proximal4.402445.63105K562DDX3X
chr177312718473127294-5'-UTR,CDS,intron-Distal,intron-Proximal3.1442315.01680HepG2PRPF8
chr177312765773127716-CDS,intron-Distal,intron-Proximal3.119185.71745HepG2SRSF1
chr177312757873127643-CDS,intron-Distal,intron-Proximal3.546706.66908HepG2PRPF8
chr177312711973127172-CDS,intron-Distal,intron-Proximal3.869276.87708HepG2EFTUD2
chr177312759373127638-CDS,intron-Distal,intron-Proximal4.854474.62947HepG2AQR
chr177312764473127750-CDS,intron-Distal,intron-Proximal4.4496010.03600HepG2GRWD1
chr177312720073127247-intron-Distal,intron-Proximal4.069206.86590K562SF3B4
chr177312720173127253-intron-Distal,intron-Proximal4.5229210.18833HepG2EFTUD2
chr177312720973127250-intron-Distal,intron-Proximal3.508768.78215HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NT5C is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NT5C is not available on ENCORE database.

  • 57 RBPs can affect the levels of NT5C.  








The Knockdown/knockout RNA-Seq assay for NT5C is not available on ENCORE database.





57 RBPs can affect the gene expression of NT5C :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NT5CENSG00000125458.2281.01300170.628200.719702.993202.01450HepG2BCCIP
NT5CENSG00000125458.2326.65540206.051600.664702.313701.67700HepG2CPSF6
NT5CENSG00000125458.2310.00950212.033600.547902.390401.53120HepG2EEF2
NT5CENSG00000125458.2185.76710264.48040-0.509702.641901.50270HepG2EIF2S2
NT5CENSG00000125458.2310.59970220.082900.496902.120201.55740HepG2EIF4A3
NT5CENSG00000125458.2210.93830294.62290-0.482002.512201.70650HepG2EIF4G1
NT5CENSG00000125458.2313.51970222.131600.497002.258801.63130HepG2FXR1
NT5CENSG00000125458.2227.12670327.80610-0.529302.643201.94170HepG2HNRNPF
NT5CENSG00000125458.2375.62140272.003100.465603.380302.64170HepG2HNRNPL
NT5CENSG00000125458.2242.94480181.181700.423101.986401.46310HepG2HNRNPU
NT5CENSG00000125458.2229.98990138.215100.734603.389402.04640HepG2KHDRBS1
NT5CENSG00000125458.2227.13460151.311100.585902.364201.32030HepG2LARP7
NT5CENSG00000125458.2397.50060222.209500.838905.787204.85020HepG2MAGOH
NT5CENSG00000125458.2447.35970296.103700.595204.983603.96370HepG2NOL12
NT5CENSG00000125458.2246.04470179.341200.456102.189001.42770HepG2PARN
NT5CENSG00000125458.2248.46170161.599900.620503.617702.78640HepG2PPIL4
NT5CENSG00000125458.2416.30440300.070500.472203.879803.20320HepG2PUM1
NT5CENSG00000125458.2337.89030182.462700.888905.575104.15230HepG2RBM27
NT5CENSG00000125458.2323.48780242.414700.416102.237201.74050HepG2NELFE
NT5CENSG00000125458.2299.72890225.802900.408502.107401.55990HepG2RECQL
NT5CENSG00000125458.2273.49510168.268400.700703.292302.41940HepG2RPS2
NT5CENSG00000125458.2299.54570171.776900.802104.418303.04420HepG2RPS5
NT5CENSG00000125458.2282.69400161.351400.808906.332105.41720HepG2SAFB2
NT5CENSG00000125458.2319.96500188.164900.765806.499805.57990HepG2SMN1
NT5CENSG00000125458.2232.34640155.567500.578602.357401.48030HepG2SMNDC1
NT5CENSG00000125458.2149.34630236.70400-0.664403.216402.71650HepG2SRSF1
NT5CENSG00000125458.2455.04090317.405700.519604.511703.75270HepG2SUCLG1
NT5CENSG00000125458.2151.28960212.79460-0.492101.975101.48770HepG2TAF15
NT5CENSG00000125458.2246.20320177.625200.470902.412901.87900HepG2TRIM56
NT5CENSG00000125458.2284.39930152.899000.895203.932402.72560HepG2UPF2
NT5CENSG00000125458.2421.72050289.730900.541504.165703.45490HepG2UTP3
NT5CENSG00000125458.2231.42720130.459000.826904.023502.69710HepG2XPO5
NT5CENSG00000125458.2306.23900164.395600.897404.825903.87820HepG2XRN2
NT5CENSG00000125458.2172.52090243.32300-0.496102.504401.86020HepG2ZC3H8
NT5CENSG00000125458.2369.12670655.71800-0.829007.228306.35160K562AQR
NT5CENSG00000125458.2851.40520609.130100.483004.056503.28810K562DDX47
NT5CENSG00000125458.2343.65310496.01830-0.529404.460603.57480K562EIF2S2
NT5CENSG00000125458.2477.21510325.927100.550003.784302.82810K562EIF4A3
NT5CENSG00000125458.2387.48480288.347500.426202.261501.49480K562FIP1L1
NT5CENSG00000125458.223.83740123.72480-2.3758012.2893010.57900K562G3BP2
NT5CENSG00000125458.2950.92810661.003300.524604.931903.92500K562GRSF1
NT5CENSG00000125458.2238.43540431.14340-0.854607.378306.44960K562HNRNPC
NT5CENSG00000125458.2376.84900237.183600.667903.300102.27520K562HNRNPM
NT5CENSG00000125458.2546.40320390.918800.483003.123102.28020K562HSPD1
NT5CENSG00000125458.2323.68470520.41680-0.685103.128101.60330K562ILF2
NT5CENSG00000125458.2273.93350417.91500-0.609403.714902.04970K562LARP7
NT5CENSG00000125458.2360.82350207.083600.801003.060102.17530K562MAGOH
NT5CENSG00000125458.2366.49000206.631300.826607.031405.46920K562MATR3
NT5CENSG00000125458.2234.00970325.48730-0.476002.512801.34460K562NCBP2
NT5CENSG00000125458.2515.62380638.53000-0.308402.498701.78560K562NSUN2
NT5CENSG00000125458.2343.69230547.56880-0.671903.615402.18670K562PABPC1
NT5CENSG00000125458.2322.63600444.24540-0.461402.334201.57050K562PCBP3
NT5CENSG00000125458.2253.03260340.74270-0.429402.229601.51010K562POLR2G
NT5CENSG00000125458.2550.50000327.351200.749806.818705.43040K562PPIG
NT5CENSG00000125458.2361.91560201.210600.846807.454506.40130K562PTBP1
NT5CENSG00000125458.2285.20000192.821000.564602.526501.72640K562RBM22
NT5CENSG00000125458.252.56890121.44830-1.208104.037502.13310K562TAF15
NT5CENSG00000125458.2429.68060199.606101.1060011.047909.47730K562TARDBP
NT5CENSG00000125458.2368.86470192.556100.937705.807804.55510K562TIA1
NT5CENSG00000125458.2237.89410371.82550-0.644303.637102.55990K562TIAL1
NT5CENSG00000125458.2303.53570189.076300.682803.232102.03590K562TRA2A
NT5CENSG00000125458.2296.76820395.22140-0.413302.125801.31220K562TRIM56
NT5CENSG00000125458.278.31720123.83990-0.661102.236601.51540K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NT5C is not available on ENCORE database.





10 RBPs can affect the splicing of NT5C :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENT5CENSG00000125458.2chr17-731271397312720073126847731269627312727573127376-0.113000.000160.00409excludedK562HNRNPC
A5SSNT5CENSG00000125458.2chr17-7312705973127376731271397312737673126847731269620.119000.000080.00473longerK562PUS1
A5SSNT5CENSG00000125458.2chr17-7312705973127376731271397312737673126847731269620.135000.002840.04518longerK562AQR
A5SSNT5CENSG00000125458.2chr17-7312705973127376731271397312737673126847731269620.182000.001270.08761longerHepG2RBM22
A5SSNT5CENSG00000125458.2chr17-7312705973127376731271397312737673126847731269620.256000.000140.01693longerHepG2SF3B4
A5SSNT5CENSG00000125458.2chr17-7312705973127376731271397312737673126847731269620.189000.000010.00163longerK562HNRNPC
A5SSNT5CENSG00000125458.2chr17-731271397312737673127275731273767312684773126962-0.239000.000030.00403shorterK562HNRNPC
A5SSNT5CENSG00000125458.2chr17-7312705973127376731271397312737673126847731269620.117000.000200.02280longerK562RBM15
A5SSNT5CENSG00000125458.2chr17-7312705973127376731271397312737673126847731269620.323000.000810.04691longerK562U2AF2
A5SSNT5CENSG00000125458.2chr17-7312705973127376731271397312737673126847731269620.103000.000580.05287longerK562UTP18
RINT5CENSG00000125458.2chr17-731271477312735373127147731272007312727573127353-0.081000.001360.06997excludedK562DROSHA
RINT5CENSG00000125458.2chr17-7312714773127353731271477312720073127275731273530.191000.000980.01218includedK562EFTUD2
RINT5CENSG00000125458.2chr17-7312714773127353731271477312720073127275731273530.168000.000540.00386includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NT5C is not avaliable on ENCORE database.