NPM2

General Information

Gene Name       : NPM2
Gene ID             : ENSG00000158806.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: NPM2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NPM2ENSG00000158806.135.2319.1312.18ENCSR000AEF
HepG2NPM2ENSG00000158806.1321.5415.2618.40ENCSR985KAT
K562NPM2ENSG00000158806.130.180.370.28ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NPM2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • NPM2 RNA is bound by 8 proteins.  







eCLIP assay for NPM2 is not avaliable on ENCORE database.





8 proteins are bound to NPM2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr82189421821894274+3'-UTR3.619353.12080HepG2XPO5
chr82189408021894168+3'-UTR,CDS,intron-Proximal3.835783.01266HepG2SF3B4
chr82189414721894311+3'-UTR,CDS,intron-Proximal3.190343.28107HepG2PABPN1
chr82188172921881804+5'-UTR,intron-Proximal3.181135.84601HepG2PRPF8
chr82189069321890787+CDS,intron-Proximal3.987557.56654HepG2PRPF8
chr82189171521891778+CDS,intron-Distal3.319344.27261HepG2GRWD1
chr82188298421883028+CDS3.419603.64266HepG2PPIG
chr82189170721891781+CDS,intron-Distal3.725095.15776HepG2BCLAF1
chr82189127321891425+intron-Distal3.787573.31570HepG2HNRNPK
chr82189207721892147+intron-Proximal5.111847.49561HepG2BCLAF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NPM2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NPM2 is not available on ENCORE database.

  • 73 RBPs can affect the levels of NPM2.  








The Knockdown/knockout RNA-Seq assay for NPM2 is not available on ENCORE database.





73 RBPs can affect the gene expression of NPM2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NPM2ENSG00000158806.9374.51880470.30970-0.328602.234101.67610HepG2ACO1
NPM2ENSG00000158806.91139.95070624.966500.867009.743907.92860HepG2AKAP8
NPM2ENSG00000158806.9678.08350472.534700.520905.659304.59760HepG2AKAP8L
NPM2ENSG00000158806.9542.32570408.004700.410502.174001.47370HepG2ASCC1
NPM2ENSG00000158806.9641.45250482.935800.409403.598202.83270HepG2AUH
NPM2ENSG00000158806.9279.08050387.63730-0.474002.375001.65360HepG2CIRBP
NPM2ENSG00000158806.9338.04260470.22600-0.476104.148703.36580HepG2CKAP4
NPM2ENSG00000158806.9429.97610199.974601.1043010.048208.81710HepG2CPSF6
NPM2ENSG00000158806.9439.51740335.677200.388702.664902.03260HepG2CELF1
NPM2ENSG00000158806.9660.10870906.67700-0.457903.735702.23690HepG2DDX47
NPM2ENSG00000158806.9388.61950202.810400.938105.118004.10660HepG2DDX55
NPM2ENSG00000158806.9404.69110227.089400.833503.911802.76020HepG2DDX59
NPM2ENSG00000158806.9429.16940292.696600.552003.427602.31190HepG2DDX5
NPM2ENSG00000158806.9735.98220405.828200.858707.543906.56960HepG2DDX6
NPM2ENSG00000158806.9369.78660146.179801.3388016.4332014.85650HepG2DNAJC21
NPM2ENSG00000158806.9196.80900144.903100.441601.962401.39560HepG2DNAJC2
NPM2ENSG00000158806.9745.56570390.058700.934509.786108.71250HepG2EIF2S1
NPM2ENSG00000158806.9945.10970431.025101.1326013.6320012.23440HepG2EIF4A3
NPM2ENSG00000158806.9627.53400459.593000.449203.363902.44290HepG2EWSR1
NPM2ENSG00000158806.9374.84480270.776400.469102.390401.32270HepG2FASTKD2
NPM2ENSG00000158806.9693.84760393.276900.819005.787104.71400HepG2FIP1L1
NPM2ENSG00000158806.9804.14270403.464100.9949010.931009.65250HepG2G3BP1
NPM2ENSG00000158806.9392.22190226.657700.791102.031001.47720HepG2GPKOW
NPM2ENSG00000158806.9408.16930164.160601.3140013.0051011.60370HepG2HNRNPC
NPM2ENSG00000158806.9480.36390328.741800.547105.364804.45250HepG2HNRNPL
NPM2ENSG00000158806.9477.78420216.306301.1432010.977909.82690HepG2HNRNPLL
NPM2ENSG00000158806.9345.38980163.075001.082604.327203.58340HepG2HNRNPU
NPM2ENSG00000158806.9516.47480407.467300.341902.139101.49670HepG2IGF2BP1
NPM2ENSG00000158806.9536.72060410.092200.388102.020901.43500HepG2IGF2BP2
NPM2ENSG00000158806.9278.49510166.574900.741405.632704.61870HepG2ILF2
NPM2ENSG00000158806.9289.81750435.81330-0.588602.678901.86200HepG2LARP4
NPM2ENSG00000158806.9779.47100435.146500.840908.217707.09880HepG2MAGOH
NPM2ENSG00000158806.9434.87190318.124600.450902.297001.55740HepG2MSI2
NPM2ENSG00000158806.9373.54350220.667900.759303.486502.39200HepG2MTPAP
NPM2ENSG00000158806.9668.11060447.857300.576903.964303.21090HepG2NCBP2
NPM2ENSG00000158806.9451.20900644.82070-0.515102.732201.31260HepG2NKRF
NPM2ENSG00000158806.9588.60860357.869800.717808.109206.82580HepG2NOL12
NPM2ENSG00000158806.9396.69520186.333901.090005.112003.60320HepG2NONO
NPM2ENSG00000158806.9336.62460191.818000.811305.029104.03160HepG2NSUN2
NPM2ENSG00000158806.9252.31870161.410400.644403.838502.85850HepG2PARN
NPM2ENSG00000158806.9205.57330422.50810-1.0393012.6735011.52450HepG2PCBP1
NPM2ENSG00000158806.9572.00430429.900200.411903.129702.55510HepG2PTBP1
NPM2ENSG00000158806.9661.63630341.627800.9535011.9794010.85790HepG2PUF60
NPM2ENSG00000158806.9501.84830362.664400.468504.479403.76450HepG2PUM1
NPM2ENSG00000158806.9588.91640362.392400.700407.240306.17250HepG2PUM2
NPM2ENSG00000158806.9145.56660277.27820-0.929703.961503.12330HepG2RAVER1
NPM2ENSG00000158806.9606.21620431.799600.489404.057603.04240HepG2RBM15
NPM2ENSG00000158806.9791.77770463.446500.7726010.307609.44960HepG2RBM22
NPM2ENSG00000158806.9282.99160422.57500-0.578404.054503.25160HepG2RBM25
NPM2ENSG00000158806.9903.74610445.749901.0196014.5860013.25110HepG2RPLP0
NPM2ENSG00000158806.9461.56240290.448500.668104.045403.08570HepG2RPS2
NPM2ENSG00000158806.9233.32050145.222700.683904.136803.37670HepG2SAFB2
NPM2ENSG00000158806.9358.67460169.349501.0826012.4154011.20490HepG2SMN1
NPM2ENSG00000158806.9579.81260283.064801.034408.966607.18670HepG2SMNDC1
NPM2ENSG00000158806.9482.15940337.321400.515304.550603.78210HepG2SRSF5
NPM2ENSG00000158806.9662.08800406.535600.703508.292207.19930HepG2SRSF7
NPM2ENSG00000158806.9758.71090534.879900.504202.559001.50570HepG2STIP1
NPM2ENSG00000158806.9550.11630383.615600.520005.248704.43970HepG2SUCLG1
NPM2ENSG00000158806.9370.17950265.415300.479902.365601.49140HepG2SUPT6H
NPM2ENSG00000158806.9807.98050201.863302.0008028.7229026.96490HepG2SUPV3L1
NPM2ENSG00000158806.9243.74970419.90050-0.784607.182206.35190HepG2TAF15
NPM2ENSG00000158806.9336.85330665.94920-0.983305.144703.72690HepG2TBRG4
NPM2ENSG00000158806.9260.44510135.282800.944904.722403.46910HepG2TFIP11
NPM2ENSG00000158806.9454.96620158.440201.521709.907009.06460HepG2TIAL1
NPM2ENSG00000158806.9283.11280159.875400.824306.723805.91220HepG2TRIM56
NPM2ENSG00000158806.9131.63990308.16440-1.227103.082602.03990HepG2U2AF2
NPM2ENSG00000158806.9708.53890353.307301.003809.519107.92230HepG2UBE2L3
NPM2ENSG00000158806.9290.48900119.225401.284709.872808.43890HepG2UCHL5
NPM2ENSG00000158806.9383.80720184.762401.054604.166202.92210HepG2UPF2
NPM2ENSG00000158806.9425.47510213.629200.9939012.4180011.16640HepG2ZC3H8
NPM2ENSG00000158806.9568.56520384.286900.565003.367802.78130HepG2ZNF622
NPM2ENSG00000158806.926.107904.265702.613503.310202.37020K562FMR1
NPM2ENSG00000158806.934.798906.045002.525104.131303.41700K562HNRNPC
NPM2ENSG00000158806.928.386009.142501.634402.394001.41820K562HNRNPL
NPM2ENSG00000158806.923.950706.831001.809802.233901.58410K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NPM2 is not available on ENCORE database.





2 RBPs can affect the splicing of NPM2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENPM2ENSG00000158806.9chr8+218827262188281721881647218817682188294621883032-0.222000.001410.05450excludedHepG2MATR3
SENPM2ENSG00000158806.9chr8+218831572188328321882946218830322189064021890734-0.071000.005510.09493excludedHepG2SRSF1
SENPM2ENSG00000158806.9chr8+218916192189178621890640218907342189202021892055-0.064000.001610.03741excludedHepG2SRSF1
SENPM2ENSG00000158806.9chr8+218822342188234121881635218817682188272621882817-0.152000.002660.05474excludedHepG2SRSF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NPM2 is not avaliable on ENCORE database.