MFAP1

General Information

Gene Name       : MFAP1
Gene ID             : ENSG00000140259.6
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MFAP1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MFAP1ENSG00000140259.645.7245.8245.77ENCSR000AEF
HepG2MFAP1ENSG00000140259.633.6340.0036.81ENCSR985KAT
K562MFAP1ENSG00000140259.641.7542.2141.98ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
eCLIPeCLIP: 4169ENCSR491HUWMFAP1K562ReleasedENCAB079FZQENCSR851BGK  






  eCLIP  
  RBP    Exp_UID    Cell_Line    ENCODE_ACCESSION    Control_ENCODE_ACCESSION    ENCODE_Antibody_ID    Antibody    Lot_num    Status    Project  
MFAP14169K562ENCSR491HUWENCSR851BGKENCAB079FZQA304-647A1ReleasedENCODE4


  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
MFAP1K562CRISPRBGKcLV21-31,BGKcLV21-32BGKcLV21-1,BGKcLV21-2NotSatisfiedENCODE4


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MFAP1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MFAP1 RNA is bound by 7 proteins.  







eCLIP assay for MFAP1 is not avaliable on ENCORE database.





7 proteins are bound to MFAP1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr154409679444096887-3'-UTR,intron-Distal6.4713940.32981K562PUM2
chr154411675344116787-5'-UTR,CDS,intron-Distal4.480798.23108K562UCHL5
chr154411674644116820-5'-UTR,CDS,intron-Distal4.044418.24591HepG2GRWD1
chr154410544944105487-CDS,intron-Distal4.012846.61895K562ZNF622
chr154410714344107197-CDS,intron-Distal4.099483.56104K562CPSF6
chr154410685244106885-CDS,intron-Distal5.202108.40383K562ZNF622
chr154410519744105235-CDS,intron-Distal3.933098.13606K562UCHL5
chr154410202244102088-CDS,intron-Distal4.6594515.20336K562UCHL5
chr154410204044102110-CDS,intron-Distal3.037978.13818K562ZNF800
chr154410675144106887-CDS,intron-Distal,intron-Proximal4.774734.11729K562CPSF6
chr154410520544105329-CDS,intron-Distal3.197755.32196K562PUM1
chr154410714244107148-CDS,intron-Distal,intron-Proximal5.027946.96356K562UCHL5
chr154410957644109601-CDS,intron-Distal3.765886.09767K562UCHL5
chr154410674844106812-CDS,intron-Distal4.7403710.57237K562ZNF622
chr154410681744106886-CDS,intron-Distal6.6037925.71772K562UCHL5
chr154410944744109501-CDS,intron-Distal3.118723.17744HepG2GRWD1
chr154410671644106817-CDS,intron-Distal5.2931927.45665K562UCHL5
chr154411670144116746-CDS,intron-Distal3.263474.24070HepG2GRWD1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MFAP1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MFAP1 is not available on ENCORE database.

  • 58 RBPs can affect the levels of MFAP1.  








The Knockdown/knockout RNA-Seq assay for MFAP1 is not available on ENCORE database.





58 RBPs can affect the gene expression of MFAP1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MFAP1ENSG00000140259.6902.95260773.528900.223101.834101.32090HepG2ACO1
MFAP1ENSG00000140259.61666.816601171.538500.508603.891203.27610HepG2AKAP1
MFAP1ENSG00000140259.61355.126601110.239500.287502.930302.22710HepG2AUH
MFAP1ENSG00000140259.6484.88210754.79590-0.638503.851402.74430HepG2BCCIP
MFAP1ENSG00000140259.6715.792301106.73460-0.628706.509905.48750HepG2CPSF6
MFAP1ENSG00000140259.6922.429001171.27310-0.344604.133703.25600HepG2DAZAP1
MFAP1ENSG00000140259.6581.271701122.28530-0.9492011.6675010.46380HepG2DDX3X
MFAP1ENSG00000140259.6739.41990926.78320-0.325801.811401.31940HepG2EIF2S1
MFAP1ENSG00000140259.6859.826601254.61370-0.545104.374903.58200HepG2GPKOW
MFAP1ENSG00000140259.6430.956301197.29700-1.4742027.1537025.52140HepG2HNRNPLL
MFAP1ENSG00000140259.6736.76870981.37550-0.413603.433702.63370HepG2IGF2BP1
MFAP1ENSG00000140259.6637.44190974.41980-0.612205.224604.32300HepG2IGF2BP2
MFAP1ENSG00000140259.6480.63770781.35330-0.701007.046705.16800HepG2LIN28B
MFAP1ENSG00000140259.6598.405001063.95880-0.830208.765907.67250HepG2NCBP2
MFAP1ENSG00000140259.6663.53490947.60790-0.514103.845403.00570HepG2PABPC4
MFAP1ENSG00000140259.6499.58820622.46870-0.317302.255901.58370HepG2PPIL4
MFAP1ENSG00000140259.6877.78000698.295400.329902.244501.54100HepG2PRPF4
MFAP1ENSG00000140259.6800.80800969.16640-0.275302.206801.70720HepG2PTBP1
MFAP1ENSG00000140259.6815.340601108.72080-0.443403.939403.24210HepG2PUF60
MFAP1ENSG00000140259.6787.799201176.98790-0.5792010.873509.86110HepG2PUM1
MFAP1ENSG00000140259.6827.736201176.10840-0.506805.747404.79270HepG2PUM2
MFAP1ENSG00000140259.61460.108401065.441900.454505.964505.27550HepG2RBM22
MFAP1ENSG00000140259.6510.05830621.50640-0.285102.114001.53780HepG2SAFB2
MFAP1ENSG00000140259.61548.447801070.629500.532303.723602.93710HepG2SF3A3
MFAP1ENSG00000140259.6783.865001008.92140-0.364103.575202.91580HepG2SF3B4
MFAP1ENSG00000140259.6806.155601063.15580-0.399205.087904.18230HepG2SLBP
MFAP1ENSG00000140259.6433.14830724.77640-0.7427012.2970011.09250HepG2SMN1
MFAP1ENSG00000140259.61669.510601203.362400.472308.288107.54880HepG2SRFBP1
MFAP1ENSG00000140259.61535.956001053.138700.5443010.123109.34500HepG2SRSF1
MFAP1ENSG00000140259.6809.81070979.07930-0.273801.976701.37750HepG2SRSF7
MFAP1ENSG00000140259.6706.118701166.87770-0.724708.523107.34720HepG2TARDBP
MFAP1ENSG00000140259.6546.34020678.11970-0.311702.098001.65050HepG2TIAL1
MFAP1ENSG00000140259.6545.38270684.20190-0.327202.725302.16400HepG2TRIM56
MFAP1ENSG00000140259.61481.03440874.869200.759409.361708.19490HepG2U2AF1
MFAP1ENSG00000140259.61258.96700916.689700.457606.546805.69140HepG2UTP3
MFAP1ENSG00000140259.6405.42370563.95750-0.476202.378501.37080HepG2XPO5
MFAP1ENSG00000140259.61110.242701422.66560-0.357704.242003.56560K562AGGF1
MFAP1ENSG00000140259.63272.858602174.893700.589508.134707.21660K562AQR
MFAP1ENSG00000140259.6938.847201263.10990-0.428005.465803.49850K562BCCIP
MFAP1ENSG00000140259.61863.134102243.26730-0.267903.051101.88370K562CPEB4
MFAP1ENSG00000140259.61378.729301994.96010-0.533003.347602.48310K562CPSF6
MFAP1ENSG00000140259.6527.03230933.81870-0.8253011.793909.47610K562DDX3X
MFAP1ENSG00000140259.61905.898502320.89910-0.284203.820303.07220K562DDX47
MFAP1ENSG00000140259.61858.800401592.883300.222602.315401.52370K562DKC1
MFAP1ENSG00000140259.61490.825201766.61490-0.244902.455401.77060K562EIF2S2
MFAP1ENSG00000140259.61227.670102029.60970-0.725305.016303.85830K562FMR1
MFAP1ENSG00000140259.61309.542601014.578000.368104.219203.49520K562FXR1
MFAP1ENSG00000140259.61482.737101766.35750-0.252502.472501.39900K562GLRX3
MFAP1ENSG00000140259.61880.083002354.18280-0.324403.200902.39020K562GRSF1
MFAP1ENSG00000140259.61796.095901359.669000.401503.178101.84580K562HNRNPK
MFAP1ENSG00000140259.61282.235301859.24500-0.536102.883001.98740K562METAP2
MFAP1ENSG00000140259.61426.255401857.07640-0.380806.081804.92030K562MTPAP
MFAP1ENSG00000140259.61777.988802063.48040-0.214803.215802.41650K562NSUN2
MFAP1ENSG00000140259.61758.438201273.009800.466003.862002.70220K562PCBP2
MFAP1ENSG00000140259.61666.183701157.970400.524805.462504.40550K562PRPF8
MFAP1ENSG00000140259.6818.101401118.28090-0.450902.141301.35590K562PSIP1
MFAP1ENSG00000140259.61752.563201390.093000.334203.263402.54790K562PTBP1
MFAP1ENSG00000140259.62523.574503037.56480-0.267403.148502.12670K562PUM2
MFAP1ENSG00000140259.61314.090001088.893600.271102.283401.50890K562SF3B4
MFAP1ENSG00000140259.6636.30200966.92240-0.603704.516203.11680K562SRFBP1
MFAP1ENSG00000140259.62196.143401362.768400.6883012.0755010.59520K562SRSF1
MFAP1ENSG00000140259.61091.785401330.38350-0.285202.304501.56470K562TIA1
MFAP1ENSG00000140259.6923.799701186.71870-0.361302.365201.43150K562UCHL5
MFAP1ENSG00000140259.61821.771202187.94390-0.264203.691202.87090K562UPF1
MFAP1ENSG00000140259.61386.051201872.16770-0.433705.096103.89120K562WDR3
MFAP1ENSG00000140259.61923.122402450.01670-0.349303.318302.36260K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MFAP1 is not available on ENCORE database.





1 RBPs can affect the splicing of MFAP1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSMFAP1ENSG00000140259.6chr15-4409757344097703440975734409766344101952441021710.053000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MFAP1 is not avaliable on ENCORE database.