MCRS1

General Information

Gene Name : MCRS1
Gene ID : ENSG00000187778.13
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: MCRS1)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	MCRS1	ENSG00000187778.13	10.88	31.89	21.39	ENCSR000AEF
HepG2	MCRS1	ENSG00000187778.13	59.28	38.26	48.77	ENCSR985KAT
K562	MCRS1	ENSG00000187778.13	54.12	49.88	52.00	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for MCRS1 is not avaliable on ENCORE database.

Proteins bound to RNA

MCRS1 RNA is bound by 13 proteins.

eCLIP assay for MCRS1 is not avaliable on ENCORE database.

13 proteins are bound to MCRS1 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr12	49952238	49952474	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.08475	5.65050	K562	DDX55
chr12	49952253	49952311	-	3'-UTR,intron-Distal,intron-Proximal	4.68428	7.90397	K562	PABPC4
chr12	49954033	49954082	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.96928	6.23016	HepG2	PRPF8
chr12	49952153	49952210	-	3'-UTR,intron-Distal,intron-Proximal	3.10029	3.86052	K562	YBX3
chr12	49952427	49952492	-	3'-UTR,CDS,intron-Distal	3.63808	3.68829	K562	YBX3
chr12	49952572	49952684	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.45206	6.67352	HepG2	PRPF8
chr12	49953069	49953134	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.06920	5.40008	K562	SF3B4
chr12	49953691	49953759	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.01735	6.92731	HepG2	PRPF8
chr12	49959991	49960101	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.79347	3.15816	HepG2	PRPF4
chr12	49959997	49960068	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.37817	5.61554	HepG2	EFTUD2
chr12	49959959	49960066	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.73925	8.08515	K562	DDX24
chr12	49959394	49959428	-	5'-UTR,CDS,intron-Distal	4.17689	3.79199	HepG2	PPIG
chr12	49959986	49960056	-	5'-UTR,CDS,intron-Distal,intron-Proximal	5.24445	13.55782	K562	SF3B4
chr12	49961853	49961894	-	5'-UTR,intron-Distal,intron-Proximal	4.08201	7.50590	K562	DDX3X
chr12	49961830	49961843	-	5'-UTR,intron-Distal	3.90776	4.84938	K562	DDX3X
chr12	49958764	49958832	-	intron-Distal,intron-Proximal	3.11300	4.81603	K562	BUD13
chr12	49954034	49954070	-	intron-Distal,intron-Proximal	4.62613	7.50107	K562	AQR
chr12	49959254	49959292	-	intron-Distal,intron-Proximal	4.16668	4.23351	K562	BUD13
chr12	49953464	49953509	-	intron-Distal,intron-Proximal	4.67206	4.86944	K562	AQR
chr12	49954070	49954078	-	intron-Distal,intron-Proximal	5.12862	4.65563	K562	AQR
chr12	49956266	49956355	-	intron-Distal	3.04680	3.25203	K562	PTBP1
chr12	49960031	49960065	-	intron-Distal,intron-Proximal	4.04272	3.44423	K562	BUD13
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for MCRS1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for MCRS1 is not available on ENCORE database.
59 RBPs can affect the levels of MCRS1.

The Knockdown/knockout RNA-Seq assay for MCRS1 is not available on ENCORE database.

59 RBPs can affect the gene expression of MCRS1 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
MCRS1	ENSG00000187778.9	355.16930	501.20630	-0.49690	3.20850	2.06200	HepG2	AATF
MCRS1	ENSG00000187778.9	1417.54370	1018.42450	0.47700	3.33660	2.76010	HepG2	AKAP1
MCRS1	ENSG00000187778.9	1147.65620	842.65410	0.44560	3.34430	2.48060	HepG2	ASCC1
MCRS1	ENSG00000187778.9	1044.30970	1230.13990	-0.23630	2.04620	1.43910	HepG2	AUH
MCRS1	ENSG00000187778.9	294.25590	385.63060	-0.39010	2.03870	1.36950	HepG2	CALR
MCRS1	ENSG00000187778.9	458.81860	677.61390	-0.56250	3.31140	2.23690	HepG2	CCAR1
MCRS1	ENSG00000187778.9	1216.13360	800.58160	0.60310	5.80240	4.70900	HepG2	CIRBP
MCRS1	ENSG00000187778.9	912.70950	724.37590	0.33330	3.66150	2.91490	HepG2	CKAP4
MCRS1	ENSG00000187778.9	704.53520	498.60670	0.49870	2.30020	1.60600	HepG2	CNOT7
MCRS1	ENSG00000187778.9	344.81080	513.17730	-0.57370	3.09320	1.62920	HepG2	CSTF2T
MCRS1	ENSG00000187778.9	641.55960	864.97790	-0.43110	4.29250	3.52290	HepG2	CELF1
MCRS1	ENSG00000187778.9	385.47080	541.13580	-0.48940	3.54640	2.50280	HepG2	DDX24
MCRS1	ENSG00000187778.9	356.89010	509.21570	-0.51280	2.73810	1.63870	HepG2	AGO1
MCRS1	ENSG00000187778.9	721.38540	917.55190	-0.34700	3.02440	2.15570	HepG2	EIF4G1
MCRS1	ENSG00000187778.9	446.48910	584.59800	-0.38880	2.40130	1.38320	HepG2	ESF1
MCRS1	ENSG00000187778.9	1184.50190	898.30540	0.39890	2.76910	2.07700	HepG2	FXR1
MCRS1	ENSG00000187778.9	483.68240	351.51520	0.46040	2.39880	1.57190	HepG2	GEMIN5
MCRS1	ENSG00000187778.9	1170.07860	843.83580	0.47150	4.01360	3.18620	HepG2	HNRNPK
MCRS1	ENSG00000187778.9	240.00990	364.15020	-0.60140	3.08750	2.29820	HepG2	NSUN2
MCRS1	ENSG00000187778.9	587.76950	823.67200	-0.48680	3.38850	2.59490	HepG2	PABPC4
MCRS1	ENSG00000187778.9	1057.02510	880.30340	0.26380	1.83880	1.33940	HepG2	PUF60
MCRS1	ENSG00000187778.9	1093.41360	934.51460	0.22650	2.51540	1.94450	HepG2	PUM1
MCRS1	ENSG00000187778.9	636.30270	934.31780	-0.55420	6.58330	5.67960	HepG2	QKI
MCRS1	ENSG00000187778.9	974.95990	1180.51130	-0.27600	2.32610	1.83990	HepG2	RBM22
MCRS1	ENSG00000187778.9	546.92560	847.91740	-0.63260	7.03820	6.00280	HepG2	RBM25
MCRS1	ENSG00000187778.9	548.12920	790.89480	-0.52900	4.57400	3.72590	HepG2	RPLP0
MCRS1	ENSG00000187778.9	866.14470	616.68350	0.49000	2.89930	2.20880	HepG2	SF3A3
MCRS1	ENSG00000187778.9	288.54010	406.47600	-0.49440	2.66480	1.97250	HepG2	SF3B1
MCRS1	ENSG00000187778.9	683.89230	528.98140	0.37050	3.53430	2.82200	HepG2	SMN1
MCRS1	ENSG00000187778.9	1033.81180	1333.32330	-0.36710	5.33310	4.70010	HepG2	SRFBP1
MCRS1	ENSG00000187778.9	530.96910	842.53010	-0.66610	8.98270	8.06600	HepG2	TAF15
MCRS1	ENSG00000187778.9	549.97680	774.26710	-0.49350	4.18430	3.16440	HepG2	TIA1
MCRS1	ENSG00000187778.9	698.24510	494.97080	0.49630	4.47610	3.87200	HepG2	TIAL1
MCRS1	ENSG00000187778.9	1659.93410	2074.21060	-0.32140	2.67200	2.09270	K562	AQR
MCRS1	ENSG00000187778.9	1902.86680	2661.72980	-0.48420	7.36020	5.79330	K562	CELF1
MCRS1	ENSG00000187778.9	793.35180	562.88000	0.49500	4.79480	3.76230	K562	EIF3G
MCRS1	ENSG00000187778.9	1019.64470	766.33260	0.41190	3.29470	2.36480	K562	FIP1L1
MCRS1	ENSG00000187778.9	501.37860	713.14480	-0.50830	3.19220	1.96510	K562	FKBP4
MCRS1	ENSG00000187778.9	1453.64260	991.89830	0.55130	8.89730	7.88550	K562	FXR1
MCRS1	ENSG00000187778.9	126.84600	453.95090	-1.83950	20.51260	18.06140	K562	G3BP2
MCRS1	ENSG00000187778.9	897.12990	630.35270	0.50910	3.12290	2.12920	K562	HNRNPM
MCRS1	ENSG00000187778.9	1242.70890	1658.74740	-0.41660	4.26830	3.15020	K562	HNRNPU
MCRS1	ENSG00000187778.9	1365.02010	1038.93790	0.39370	3.25160	2.39120	K562	HSPD1
MCRS1	ENSG00000187778.9	1127.26560	831.21950	0.43940	4.16790	3.13200	K562	MAGOH
MCRS1	ENSG00000187778.9	1805.55670	2307.40130	-0.35380	3.07340	1.87980	K562	MSI2
MCRS1	ENSG00000187778.9	565.18080	1281.01070	-1.18050	18.09140	16.04000	K562	PCBP3
MCRS1	ENSG00000187778.9	528.15490	982.60390	-0.89560	14.10070	12.35690	K562	POLR2G
MCRS1	ENSG00000187778.9	1252.84900	869.98690	0.52600	5.16080	3.98360	K562	PPIG
MCRS1	ENSG00000187778.9	1237.68280	985.87050	0.32810	2.02580	1.37930	K562	PRPF8
MCRS1	ENSG00000187778.9	1188.23180	807.62380	0.55700	6.89000	5.87770	K562	PTBP1
MCRS1	ENSG00000187778.9	2052.26760	2461.50740	-0.26230	2.90820	1.92470	K562	PUM2
MCRS1	ENSG00000187778.9	1042.08610	774.10770	0.42880	2.11970	1.38850	K562	RBM22
MCRS1	ENSG00000187778.9	633.70670	471.95670	0.42510	3.44480	2.48650	K562	SF3B4
MCRS1	ENSG00000187778.9	1031.88180	791.80370	0.38200	1.99610	1.38460	K562	SRSF1
MCRS1	ENSG00000187778.9	861.57870	1118.47020	-0.37650	3.59980	1.84950	K562	SRSF9
MCRS1	ENSG00000187778.9	1212.95530	985.54280	0.29940	2.50500	1.72540	K562	SYNCRIP
MCRS1	ENSG00000187778.9	215.41540	445.60040	-1.04860	5.98860	3.47430	K562	TAF15
MCRS1	ENSG00000187778.9	1443.56970	801.22100	0.84930	5.70870	4.67120	K562	TARDBP
MCRS1	ENSG00000187778.9	319.88160	473.11060	-0.56460	4.03490	2.07040	K562	TBRG4
MCRS1	ENSG00000187778.9	1044.01680	772.90390	0.43370	2.57310	1.78680	K562	TIA1
MCRS1	ENSG00000187778.9	994.74580	758.77050	0.39060	2.27510	1.30630	K562	TRA2A
MCRS1	ENSG00000187778.9	314.20520	454.39360	-0.53220	4.03470	3.06490	K562	U2AF2
MCRS1	ENSG00000187778.9	1005.68540	1199.63330	-0.25440	2.64240	1.94040	K562	UPF1
MCRS1	ENSG00000187778.9	1769.19740	2336.82620	-0.40150	4.25410	3.14590	K562	ZC3H8
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for MCRS1 is not available on ENCORE database.

27 RBPs can affect the splicing of MCRS1 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	MCRS1	ENSG00000187778.9	chr12	-	49960173	49960407			49959859	49959998	49960504	49960624	0.05900	0.00039	0.03785	included	HepG2	G3BP1
SE	MCRS1	ENSG00000187778.9	chr12	-	49960504	49960624			49959859	49959998	49961830	49961936	-0.09400	0.00341	0.05590	excluded	K562	SRSF1
SE	MCRS1	ENSG00000187778.9	chr12	-	49960504	49960624			49959859	49959998	49961830	49961936	-0.13800	0.00005	0.00163	excluded	K562	SF3B4
SE	MCRS1	ENSG00000187778.9	chr12	-	49960504	49960624			49959859	49959998	49961830	49961936	-0.07000	0.00008	0.03162	excluded	K562	PUM1
SE	MCRS1	ENSG00000187778.9	chr12	-	49961429	49961532			49960504	49960624	49961830	49961884	0.05200	0.00432	0.08569	included	HepG2	HNRNPK
SE	MCRS1	ENSG00000187778.9	chr12	-	49961429	49961532			49960504	49960624	49961830	49961884	0.06200	0.00114	0.07662	included	HepG2	DDX3X
SE	MCRS1	ENSG00000187778.9	chr12	-	49960173	49960407			49959859	49959998	49960504	49960624	0.08600	0.00023	0.04309	included	HepG2	TIA1
SE	MCRS1	ENSG00000187778.9	chr12	-	49961429	49961532			49960504	49960624	49961830	49961884	0.07200	0.00032	0.02484	included	HepG2	NCBP2
SE	MCRS1	ENSG00000187778.9	chr12	-	49961429	49961532			49960504	49960624	49961830	49961884	-0.05200	0.00188	0.08046	excluded	K562	EFTUD2
SE	MCRS1	ENSG00000187778.9	chr12	-	49960504	49960624			49959859	49959998	49961830	49961936	-0.09000	0.00300	0.09479	excluded	HepG2	MATR3
SE	MCRS1	ENSG00000187778.9	chr12	-	49960522	49960624			49959859	49959998	49961830	49961936	-0.22500	0.00079	0.08390	excluded	HepG2	PCBP2
SE	MCRS1	ENSG00000187778.9	chr12	-	49960504	49960624			49959859	49959998	49961830	49961936	-0.17000	0.00000	0.00000	excluded	HepG2	SRSF1
SE	MCRS1	ENSG00000187778.9	chr12	-	49960504	49960624			49959859	49959998	49961830	49961936	-0.09100	0.00038	0.02128	excluded	HepG2	SF3B4
SE	MCRS1	ENSG00000187778.9	chr12	-	49961429	49961532			49960504	49960624	49961830	49961884	-0.10600	0.00000	0.00021	excluded	K562	U2AF2
SE	MCRS1	ENSG00000187778.9	chr12	-	49953235	49953318			49952996	49953084	49953511	49953604	-0.15000	0.00146	0.02732	excluded	K562	U2AF2
SE	MCRS1	ENSG00000187778.9	chr12	-	49960173	49960407			49959859	49959998	49960504	49960624	0.05700	0.00017	0.00918	included	K562	HNRNPU
SE	MCRS1	ENSG00000187778.9	chr12	-	49961429	49961588			49959859	49960624	49961830	49961936	0.08200	0.00169	0.04067	included	K562	RBM15
A3SS	MCRS1	ENSG00000187778.9	chr12	-	49959311	49959462			49959311	49959450	49959859	49959998	0.05900	0.00000	0.00000	longer	K562	AQR
A3SS	MCRS1	ENSG00000187778.9	chr12	-	49953235	49953351			49953235	49953318	49953511	49953604	0.10600	0.00000	0.00000	longer	K562	AQR
A3SS	MCRS1	ENSG00000187778.9	chr12	-	49953511	49953637			49953511	49953604	49953721	49953750	0.07000	0.00000	0.00000	longer	K562	AQR
A3SS	MCRS1	ENSG00000187778.9	chr12	-	49952425	49952533			49952425	49952512	49952625	49952753	0.26600	0.00000	0.00000	longer	K562	AQR
A3SS	MCRS1	ENSG00000187778.9	chr12	-	49958519	49958733			49958519	49958678	49959311	49959450	0.15400	0.00000	0.00000	longer	K562	AQR
A3SS	MCRS1	ENSG00000187778.9	chr12	-	49958263	49958444			49958263	49958373	49958519	49958678	0.10300	0.00000	0.00000	longer	K562	AQR
A3SS	MCRS1	ENSG00000187778.9	chr12	-	49954023	49954153			49954023	49954148	49956783	49956943	-0.10500	0.00002	0.00018	shorter	K562	AQR
A3SS	MCRS1	ENSG00000187778.9	chr12	-	49952425	49952533			49952425	49952512	49952625	49952753	0.10400	0.00002	0.00354	longer	K562	RBM15
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.20500	0.00279	0.04053	included	K562	SF3B4
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.12800	0.00033	0.02143	included	HepG2	BCCIP
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.14800	0.00076	0.01816	included	HepG2	PCBP2
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.24300	0.00000	0.00000	included	K562	PUS1
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.18400	0.00016	0.00303	included	HepG2	SF3A3
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.11100	0.00297	0.07907	included	HepG2	TIA1
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.22300	0.00000	0.00001	included	HepG2	PRPF8
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	-0.07900	0.00567	0.09166	excluded	K562	SRSF1
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	-0.21600	0.00074	0.04280	excluded	HepG2	HNRNPUL1
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.09900	0.00913	0.08381	included	K562	AGGF1
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.09700	0.00004	0.00192	included	HepG2	IGF2BP3
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.10800	0.00003	0.00185	included	HepG2	MATR3
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.11000	0.00621	0.06537	included	HepG2	PCBP1
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.19600	0.00000	0.00004	included	K562	AKAP8L
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.22200	0.00000	0.00001	included	K562	RBM15
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.18000	0.00000	0.00000	included	HepG2	G3BP1
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.18700	0.00027	0.00528	included	K562	U2AF2
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.09700	0.00004	0.00095	included	HepG2	NCBP2
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.15600	0.00072	0.04323	included	HepG2	HNRNPU
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.09600	0.00289	0.02245	included	HepG2	SF3B4
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.17200	0.00000	0.00000	included	HepG2	HNRNPK
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.12000	0.00051	0.00709	included	K562	EFTUD2
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	-0.10400	0.00194	0.09358	excluded	K562	SAFB
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	-0.22400	0.00006	0.01479	excluded	HepG2	RBFOX2
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	0.22300	0.00000	0.00000	included	K562	AQR
RI	MCRS1	ENSG00000187778.9	chr12	-	49959859	49960624			49959859	49959998	49960504	49960624	-0.08600	0.00083	0.01890	excluded	K562	PTBP1
MXE	MCRS1	ENSG00000187778.9	chr12	-	49952996	49953084	49953235	49953351	49952625	49952753	49953511	49953604	0.11500	0.00000	0.00000	1included	K562	AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

MCRS1

General Information

Functions

Localization

Domains (AlphaFold: MCRS1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for MCRS1 is not avaliable on ENCORE database.

13 proteins are bound to MCRS1 RNA:

eCLIP assay for MCRS1 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for MCRS1 is not available on ENCORE database.

59 RBPs can affect the gene expression of MCRS1 :

The Knockdown/knockout RNA-Seq assay for MCRS1 is not available on ENCORE database.

27 RBPs can affect the splicing of MCRS1 :

The Knockdown/knockout RNA-Seq assay for MCRS1 is not avaliable on ENCORE database.