FXN

General Information

Gene Name       : FXN
Gene ID             : ENSG00000165060.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FXN)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FXNENSG00000165060.1225.1122.1723.64ENCSR000AEF
HepG2FXNENSG00000165060.1242.1755.3448.76ENCSR985KAT
K562FXNENSG00000165060.1232.1634.6633.41ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FXN is not avaliable on ENCORE database.



Proteins bound to RNA
  • FXN RNA is bound by 10 proteins.  







eCLIP assay for FXN is not avaliable on ENCORE database.





10 proteins are bound to FXN RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr97168778171687859+3'-UTR,intron-Distal4.320054.97297K562TIA1
chr97168785571687949+3'-UTR,intron-Distal3.532943.96118HepG2LARP4
chr97165069771650864+5'-UTR,CDS,intron-Proximal4.292477.94128HepG2DDX3X
chr97167989471679953+CDS,intron-Proximal3.188887.59396K562YBX3
chr97168179971681834+intron-Distal3.934663.10243K562SLTM
chr97165955871659642+intron-Distal3.743833.06084HepG2HNRNPK
chr97168565071685698+intron-Distal4.031593.39362HepG2CSTF2
chr97168336771683471+intron-Distal5.244428.16466K562SLTM
chr97168446971684519+intron-Distal4.336464.14527K562SLTM
chr97168532471685419+intron-Distal4.587715.09502K562SLTM
chr97168432471684395+intron-Distal4.220583.87995K562UCHL5
chr97168334371683377+intron-Distal4.706783.51211HepG2SLTM
chr97168298771683071+intron-Distal3.748675.08142K562SLTM
chr97168302071683077+intron-Distal4.306574.12522HepG2HLTF
chr97168195971682046+intron-Distal3.850825.57381HepG2SLTM
chr97166494271665032+intron-Distal4.537525.05488HepG2QKI
chr97168195671682028+intron-Distal3.817434.19798K562SLTM
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FXN is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FXN is not available on ENCORE database.

  • 62 RBPs can affect the levels of FXN.  








The Knockdown/knockout RNA-Seq assay for FXN is not available on ENCORE database.





62 RBPs can affect the gene expression of FXN :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FXNENSG00000165060.7176.22470295.89240-0.747704.031102.77990HepG2AKAP8
FXNENSG00000165060.7382.90420601.35060-0.651207.513306.47180HepG2AUH
FXNENSG00000165060.7197.91520312.24410-0.657803.553602.16770HepG2BUD13
FXNENSG00000165060.7236.00690495.45430-1.069908.512706.80200HepG2CCAR1
FXNENSG00000165060.7204.50790350.79520-0.778504.864803.97470HepG2CPSF6
FXNENSG00000165060.7408.64940544.76820-0.414802.942102.28280HepG2CELF1
FXNENSG00000165060.7437.15100585.66410-0.421903.683402.84820HepG2DAZAP1
FXNENSG00000165060.7231.28500374.32230-0.694603.809302.91720HepG2DDX55
FXNENSG00000165060.7238.38470398.35480-0.740803.275102.21340HepG2DDX59
FXNENSG00000165060.7230.16080392.05570-0.768404.629903.84830HepG2DDX6
FXNENSG00000165060.7221.04090321.13560-0.538903.365502.59500HepG2DNAJC21
FXNENSG00000165060.7245.84720318.29490-0.372602.213501.61720HepG2DNAJC2
FXNENSG00000165060.7102.41830376.88790-1.8797020.0835018.58590HepG2EIF2S1
FXNENSG00000165060.7416.35050553.55330-0.410902.264601.52230HepG2EIF4G2
FXNENSG00000165060.7461.23320690.43180-0.582006.666205.80010HepG2ETF1
FXNENSG00000165060.7199.17940370.81310-0.896605.448503.91790HepG2FUS
FXNENSG00000165060.794.72890389.83160-2.0410024.1984022.31700HepG2G3BP1
FXNENSG00000165060.7167.28340397.64520-1.2492010.591309.39600HepG2GPKOW
FXNENSG00000165060.7270.41660360.62440-0.415301.915901.32720HepG2HNRNPC
FXNENSG00000165060.7397.45890533.46620-0.424603.300702.56940HepG2HNRNPL
FXNENSG00000165060.7271.92540358.24030-0.397702.480201.90520HepG2HNRNPU
FXNENSG00000165060.7215.00910340.54560-0.663504.337403.33670HepG2MSI2
FXNENSG00000165060.7261.41820387.03980-0.566102.207501.34790HepG2MTPAP
FXNENSG00000165060.7435.42700580.74840-0.415502.921202.13760HepG2NOL12
FXNENSG00000165060.7220.84100343.75040-0.638402.424801.40820HepG2NONO
FXNENSG00000165060.7258.14710385.34030-0.577903.195902.42140HepG2PABPC4
FXNENSG00000165060.7523.23560393.660200.410402.972002.34640HepG2PCBP1
FXNENSG00000165060.7242.07460319.52200-0.400502.099201.45000HepG2PPIL4
FXNENSG00000165060.7124.85200288.73310-1.209508.506707.17630HepG2PRPF8
FXNENSG00000165060.7395.36140554.40160-0.487803.218002.58160HepG2PUF60
FXNENSG00000165060.7378.94520588.10360-0.634105.610104.66830HepG2PUM2
FXNENSG00000165060.7272.96230433.86200-0.668503.979703.24920HepG2QKI
FXNENSG00000165060.7198.75500285.61430-0.523102.137401.43870HepG2RRP9
FXNENSG00000165060.7255.06810417.92950-0.712403.381902.51300HepG2SNRNP70
FXNENSG00000165060.7341.85660651.78250-0.9310014.3556013.45150HepG2SRFBP1
FXNENSG00000165060.7436.93770547.42800-0.325202.031301.48490HepG2SRSF5
FXNENSG00000165060.7262.30920354.11510-0.433002.448701.92240HepG2SRSF9
FXNENSG00000165060.7464.84080622.54460-0.421403.627302.93370HepG2SUCLG1
FXNENSG00000165060.7136.51760284.12140-1.057408.480406.89970HepG2SUPT6H
FXNENSG00000165060.7120.98890372.62450-1.6228014.9390013.58480HepG2SUPV3L1
FXNENSG00000165060.7243.83500348.10350-0.513603.260002.72400HepG2TIAL1
FXNENSG00000165060.7258.88460351.20870-0.440002.820602.25250HepG2TRIM56
FXNENSG00000165060.7204.46090415.37500-1.022602.733501.75080HepG2U2AF2
FXNENSG00000165060.7417.41340573.39030-0.458002.230401.48320HepG2UBE2L3
FXNENSG00000165060.7531.88220385.852700.463003.961503.26390HepG2UTP3
FXNENSG00000165060.7159.36620370.66640-1.2178015.1787013.81090HepG2ZC3H8
FXNENSG00000165060.7385.48410552.16860-0.518403.196702.57460K562AQR
FXNENSG00000165060.7224.15950332.12250-0.567203.248202.39690K562CPSF6
FXNENSG00000165060.7666.81970454.296100.553606.279305.35410K562DDX47
FXNENSG00000165060.7172.48250319.59200-0.889806.082304.68380K562EFTUD2
FXNENSG00000165060.7353.38690537.28110-0.604405.769704.78800K562EIF2S2
FXNENSG00000165060.7373.50880252.590300.564204.036503.08550K562EIF3G
FXNENSG00000165060.7215.91530337.95810-0.646403.823702.81210K562FMR1
FXNENSG00000165060.7145.63130223.32110-0.616802.865901.50110K562FUS
FXNENSG00000165060.7421.64810229.943300.874708.651207.65360K562FXR1
FXNENSG00000165060.7167.52260248.85560-0.571002.865701.40450K562G3BP1
FXNENSG00000165060.7159.96590317.08230-0.987107.493106.18400K562GPKOW
FXNENSG00000165060.7186.20750293.16960-0.654803.548002.88260K562HNRNPC
FXNENSG00000165060.7370.23830272.986300.439502.574201.68660K562MATR3
FXNENSG00000165060.7219.27890380.52250-0.795205.277504.12570K562PCBP3
FXNENSG00000165060.7182.61100291.86100-0.676504.018203.04680K562POLR2G
FXNENSG00000165060.7161.39020262.84680-0.703703.615102.56290K562PSIP1
FXNENSG00000165060.7184.78070260.56280-0.495802.346001.68770K562SRSF1
FXNENSG00000165060.7410.74680292.761800.488403.184102.30350K562SYNCRIP
FXNENSG00000165060.7219.98780318.68430-0.534702.654401.65900K562UCHL5
FXNENSG00000165060.7342.46010443.36240-0.372602.506701.82120K562UPF1
FXNENSG00000165060.7507.12200394.502800.362202.790601.94070K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FXN is not available on ENCORE database.





4 RBPs can affect the splicing of FXN :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFXNENSG00000165060.7chr9+716875277168774671679853716799517171481671715094-0.203000.002580.04470excludedK562SRSF1
SEFXNENSG00000165060.7chr9+7168752771687746716798537167995171714816717150940.194000.003550.05686includedK562SF3B4
SEFXNENSG00000165060.7chr9+716680557166817671661300716613987167985371679959-0.086000.000010.00022excludedHepG2U2AF2
SEFXNENSG00000165060.7chr9+716680557166817671661300716613987167985371679959-0.126000.000060.00550excludedK562EFTUD2
SEFXNENSG00000165060.7chr9+7168752771687746716798537167995171714816717150940.246000.003770.05775includedK562U2AF2
SEFXNENSG00000165060.7chr9+716680557166817671661300716613987167985371679959-0.095000.006690.09047excludedK562U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FXN is not avaliable on ENCORE database.