FBXL21

General Information

Gene Name       : FBXL21
Gene ID             : ENSG00000164616.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FBXL21)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FBXL21ENSG00000164616.160.000.000.00ENCSR000AEF
HepG2FBXL21ENSG00000164616.169.4419.5014.47ENCSR985KAT
K562FBXL21ENSG00000164616.160.000.000.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FBXL21 is not avaliable on ENCORE database.



Proteins bound to RNA
  • FBXL21 RNA is bound by 8 proteins.  







eCLIP assay for FBXL21 is not avaliable on ENCORE database.





8 proteins are bound to FBXL21 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5135276660135276741+CDS,intron-Proximal5.083526.38747HepG2AQR
chr5135276226135276304+CDS4.636816.03821HepG2GRWD1
chr5135272551135272648+CDS3.150824.75490HepG2GRWD1
chr5135272623135272655+CDS,intron-Proximal4.580344.70478HepG2BCLAF1
chr5135276177135276220+CDS,intron-Proximal4.616373.77802HepG2U2AF2
chr5135272538135272604+CDS3.568805.15500HepG2BCLAF1
chr5135272447135272494+CDS,intron-Proximal4.245665.36861HepG2U2AF2
chr5135271365135271447+intron-Distal,intron-Proximal3.210353.60157HepG2GRWD1
chr5135266231135266289+intron-Distal,intron-Proximal5.8728410.35592HepG2EFTUD2
chr5135271007135271048+intron-Distal,intron-Proximal4.313734.08604HepG2PPIG
chr5135272774135272822+intron-Distal3.274133.42396HepG2U2AF2
chr5135266354135266409+intron-Distal5.477146.82887HepG2EFTUD2
chr5135271157135271241+intron-Distal,intron-Proximal4.082494.02395HepG2KHSRP
chr5135266296135266346+intron-Distal5.767569.61799HepG2EFTUD2
chr5135271118135271190+intron-Distal,intron-Proximal5.892516.69228HepG2PRPF8
chr5135266150135266219+intron-Proximal6.2284517.78886HepG2PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FBXL21 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FBXL21 is not available on ENCORE database.

  • 53 RBPs can affect the levels of FBXL21.  








The Knockdown/knockout RNA-Seq assay for FBXL21 is not available on ENCORE database.





53 RBPs can affect the gene expression of FBXL21 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FBXL21ENSG00000164616.10303.69890156.083300.960205.967304.64080HepG2ABCF1
FBXL21ENSG00000164616.10301.76200191.903800.652903.690502.55770HepG2ADAR
FBXL21ENSG00000164616.10259.96190138.253900.910906.051704.55900HepG2CSTF2
FBXL21ENSG00000164616.10223.79680382.10110-0.771807.079406.14080HepG2CELF1
FBXL21ENSG00000164616.10324.78860242.659300.420502.745201.91440HepG2DDX19B
FBXL21ENSG00000164616.10383.53770225.007500.769305.716304.77850HepG2DDX21
FBXL21ENSG00000164616.10329.00160220.387400.578003.415002.39440HepG2DDX24
FBXL21ENSG00000164616.10492.09990251.018500.971103.483102.73620HepG2DKC1
FBXL21ENSG00000164616.10132.63370193.24450-0.543002.360601.70470HepG2DNAJC21
FBXL21ENSG00000164616.10320.71650212.616900.592903.621302.40660HepG2EIF3G
FBXL21ENSG00000164616.10669.06410276.299701.275805.112804.24490HepG2EIF4A3
FBXL21ENSG00000164616.10714.76700405.339500.8182011.435909.96370HepG2EIF4G1
FBXL21ENSG00000164616.10251.40800135.279700.894005.506904.01200HepG2ESF1
FBXL21ENSG00000164616.10528.10470358.194800.560005.370604.58120HepG2ETF1
FBXL21ENSG00000164616.10366.22150256.393400.514303.112102.22910HepG2EWSR1
FBXL21ENSG00000164616.10566.36230274.290601.045906.587905.20520HepG2G3BP2
FBXL21ENSG00000164616.10212.34880139.094500.610302.397801.57110HepG2GEMIN5
FBXL21ENSG00000164616.10184.69330250.49510-0.439702.231301.34730HepG2HDGF
FBXL21ENSG00000164616.10316.97990195.095600.700104.141603.37430HepG2HNRNPA1
FBXL21ENSG00000164616.10278.21860374.33560-0.428102.980402.28350HepG2HNRNPL
FBXL21ENSG00000164616.10450.71660264.269000.770103.876202.67090HepG2KHSRP
FBXL21ENSG00000164616.10329.62930227.677300.533802.372901.60750HepG2LARP4
FBXL21ENSG00000164616.10321.70410407.46260-0.340902.027201.37160HepG2NOL12
FBXL21ENSG00000164616.10150.4972089.297900.752902.598101.87220HepG2NSUN2
FBXL21ENSG00000164616.1037.65030212.86980-2.499204.008902.92830HepG2PABPC1
FBXL21ENSG00000164616.10106.08870255.61600-1.268702.835602.10590HepG2PABPC4
FBXL21ENSG00000164616.10403.19260265.088900.604902.754501.53990HepG2PRPF6
FBXL21ENSG00000164616.10307.29720412.85580-0.426003.392002.74940HepG2PUM1
FBXL21ENSG00000164616.10188.78460267.24050-0.501402.857002.23370HepG2PUS1
FBXL21ENSG00000164616.10114.21730243.38970-1.091504.751103.84120HepG2RAVER1
FBXL21ENSG00000164616.10227.28600299.38460-0.397501.924501.47150HepG2RBM22
FBXL21ENSG00000164616.10165.03570254.44100-0.624602.529701.51660HepG2RCC2
FBXL21ENSG00000164616.10586.73140289.377201.0196014.2045013.15840HepG2NELFE
FBXL21ENSG00000164616.10484.32360269.549000.845309.509708.46900HepG2RECQL
FBXL21ENSG00000164616.10219.17700126.090200.797502.425601.77910HepG2RPLP0
FBXL21ENSG00000164616.10414.22230288.986800.519302.978902.14960HepG2RPS2
FBXL21ENSG00000164616.10433.00480233.603800.890203.442602.54990HepG2RPS3A
FBXL21ENSG00000164616.10100.31610191.97620-0.936405.680104.80960HepG2SAFB2
FBXL21ENSG00000164616.10373.79070270.691800.465503.024402.40900HepG2SF3B4
FBXL21ENSG00000164616.10144.44790247.83400-0.778803.868302.71970HepG2SMNDC1
FBXL21ENSG00000164616.10466.00450338.144000.462603.713103.15880HepG2SRFBP1
FBXL21ENSG00000164616.10227.67940383.99620-0.754107.021306.08840HepG2SRSF5
FBXL21ENSG00000164616.10756.19010293.589201.3648031.8346030.52950HepG2SSB
FBXL21ENSG00000164616.10333.25750436.73150-0.390102.810402.18530HepG2SUCLG1
FBXL21ENSG00000164616.10479.02360219.025801.128909.713408.57430HepG2SUPV3L1
FBXL21ENSG00000164616.10469.10710254.020900.884909.807308.85620HepG2TAF15
FBXL21ENSG00000164616.10344.16090209.483900.716104.346403.74850HepG2TIAL1
FBXL21ENSG00000164616.10114.76630211.33630-0.880805.824105.06010HepG2TRIM56
FBXL21ENSG00000164616.10195.15990129.398100.592702.652101.90950HepG2UCHL5
FBXL21ENSG00000164616.10522.33160200.610001.380509.258807.37180HepG2UPF2
FBXL21ENSG00000164616.10432.99940215.606301.005908.223306.98860HepG2XRN2
FBXL21ENSG00000164616.10187.44320104.690900.840204.796303.95270HepG2ZC3H8
FBXL21ENSG00000164616.10132.34080242.71630-0.875003.886403.26760HepG2ZNF622
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FBXL21 is not available on ENCORE database.





6 RBPs can affect the splicing of FBXL21 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFBXL21ENSG00000164616.10chr5+1352713111352714131352710081352711281352722821352723900.432000.000790.01689includedHepG2U2AF1
SEFBXL21ENSG00000164616.10chr5+1352713111352714131352710081352711281352722821352723900.696000.000000.00004includedHepG2HNRNPK
SEFBXL21ENSG00000164616.10chr5+1352713111352714131352710081352711281352722821352723900.494000.001000.01415includedHepG2U2AF2
SEFBXL21ENSG00000164616.10chr5+1352713111352714131352710081352711281352722821352723900.425000.001410.07421includedHepG2AKAP1
SEFBXL21ENSG00000164616.10chr5+1352713111352714131352710081352711281352722821352723900.570000.000120.01442includedHepG2IGF2BP3
SEFBXL21ENSG00000164616.10chr5+135272788135272880135272492135272649135273113135273236-0.540000.000010.00110excludedHepG2HNRNPU

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FBXL21 is not avaliable on ENCORE database.