CWC25

General Information

Gene Name : CWC25
Gene ID : ENSG00000273559.4
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: CWC25)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	CWC25	ENSG00000273559.4	18.89	20.21	19.55	ENCSR000AEF
HepG2	CWC25	ENSG00000273559.4	12.55	17.38	14.96	ENCSR985KAT
K562	CWC25	ENSG00000273559.4	16.53	18.44	17.48	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for CWC25 is not avaliable on ENCORE database.

Proteins bound to RNA

CWC25 RNA is bound by 10 proteins.

eCLIP assay for CWC25 is not avaliable on ENCORE database.

10 proteins are bound to CWC25 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr17	36966618	36966711	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	5.05093	5.13952	K562	SF3B4
chr17	36971269	36971352	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	3.54620	11.54327	HepG2	PPIG
chr17	36971295	36971355	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	4.66376	5.90930	HepG2	AQR
chr17	36969096	36969116	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	3.15233	3.02345	K562	ZNF622
chr17	36965954	36966020	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	5.23092	7.05570	HepG2	BCLAF1
chr17	36971115	36971168	-	3'-UTR,5'-UTR,CDS,intron-Distal	3.22575	5.66840	K562	ZNF622
chr17	36965956	36966007	-	3'-UTR,5'-UTR,CDS,intron-Distal	3.74126	5.86107	HepG2	PPIG
chr17	36966720	36966754	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	4.52240	4.90367	K562	ZNF622
chr17	36965975	36966012	-	3'-UTR,5'-UTR,CDS,intron-Distal	3.86741	3.34184	HepG2	GRWD1
chr17	36966701	36966787	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	3.56647	4.82719	K562	TRA2A
chr17	36971269	36971351	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	3.76069	9.12722	K562	ZNF622
chr17	36958415	36958449	-	3'-UTR,CDS,intron-Distal	3.96330	3.32022	K562	UCHL5
chr17	36971263	36971340	-	3'-UTR,5'-UTR,CDS,intron-Distal	3.80052	8.77730	K562	UCHL5
chr17	36971266	36971344	-	3'-UTR,5'-UTR,CDS,intron-Distal	3.84262	7.28307	HepG2	BCLAF1
chr17	36971285	36971349	-	3'-UTR,5'-UTR,CDS,intron-Distal	4.23471	5.05331	K562	GRWD1
chr17	36958983	36959039	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.87430	7.02609	K562	UCHL5
chr17	36958387	36958436	-	3'-UTR,CDS,intron-Distal	3.13808	3.94979	HepG2	BCLAF1
chr17	36971261	36971350	-	3'-UTR,5'-UTR,CDS,intron-Distal	4.85624	5.82083	HepG2	GRWD1
chr17	36963019	36963098	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.20995	4.78556	K562	LIN28B
chr17	36966638	36966735	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	4.09756	4.07325	HepG2	SF3B4
chr17	36971274	36971345	-	3'-UTR,5'-UTR,CDS,intron-Distal	4.22330	9.15724	HepG2	BUD13
chr17	36959065	36959116	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.26550	3.39477	K562	BUD13
chr17	36977150	36977192	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.45243	7.38586	HepG2	PPIG
chr17	36977154	36977271	-	5'-UTR,CDS,intron-Distal	3.96129	4.06415	K562	TRA2A
chr17	36981429	36981481	-	5'-UTR,CDS,intron-Distal	3.37914	3.12941	K562	UCHL5
chr17	36977271	36977321	-	5'-UTR,CDS,intron-Distal	3.31843	4.24993	HepG2	PPIG
chr17	36981418	36981466	-	5'-UTR,CDS,intron-Distal	3.81638	4.68902	HepG2	PPIG
chr17	36981427	36981488	-	5'-UTR,CDS,intron-Distal	3.87940	8.54758	K562	ZNF622
chr17	36977192	36977236	-	5'-UTR,CDS,intron-Distal	4.05745	7.55042	HepG2	PPIG
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for CWC25 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for CWC25 is not available on ENCORE database.
41 RBPs can affect the levels of CWC25.

The Knockdown/knockout RNA-Seq assay for CWC25 is not available on ENCORE database.

41 RBPs can affect the gene expression of CWC25 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CWC25	ENSG00000108296.7	638.89270	471.00210	0.43970	2.26510	1.77880	HepG2	AKAP1
CWC25	ENSG00000108296.7	546.15970	702.28040	-0.36270	3.03560	2.32140	HepG2	AUH
CWC25	ENSG00000108296.7	597.66790	430.82050	0.47220	2.15330	1.33080	HepG2	BCCIP
CWC25	ENSG00000108296.7	529.62910	370.26140	0.51630	3.20000	2.37060	HepG2	CIRBP
CWC25	ENSG00000108296.7	533.53980	736.50230	-0.46510	3.55950	2.09360	HepG2	DDX47
CWC25	ENSG00000108296.7	296.68650	402.21120	-0.43900	2.88080	2.16630	HepG2	DNAJC21
CWC25	ENSG00000108296.7	497.68660	731.96830	-0.55650	3.70320	2.76990	HepG2	EIF4G2
CWC25	ENSG00000108296.7	445.94240	282.27230	0.65970	4.88800	3.85870	HepG2	FUBP3
CWC25	ENSG00000108296.7	360.71600	511.86280	-0.50490	2.77240	2.13090	HepG2	GPKOW
CWC25	ENSG00000108296.7	563.16870	711.78140	-0.33790	2.47130	1.58120	HepG2	HNRNPA2B1
CWC25	ENSG00000108296.7	554.57900	390.16550	0.50720	3.25150	2.49490	HepG2	HNRNPK
CWC25	ENSG00000108296.7	314.78090	448.68730	-0.51140	4.32340	3.57980	HepG2	HNRNPU
CWC25	ENSG00000108296.7	562.94600	415.56090	0.43780	2.38510	1.77450	HepG2	MAGOH
CWC25	ENSG00000108296.7	570.81620	380.97940	0.58320	3.97380	3.11900	HepG2	PABPC4
CWC25	ENSG00000108296.7	473.01340	382.08890	0.30790	1.94280	1.41980	HepG2	PCBP1
CWC25	ENSG00000108296.7	373.17300	733.08680	-0.97410	12.34310	11.20370	HepG2	PUF60
CWC25	ENSG00000108296.7	614.46520	778.24800	-0.34090	3.20490	2.57770	HepG2	PUM1
CWC25	ENSG00000108296.7	678.38120	458.52070	0.56500	2.49080	1.82060	HepG2	RAVER1
CWC25	ENSG00000108296.7	1008.34740	673.93350	0.58120	7.63120	6.87050	HepG2	RBM22
CWC25	ENSG00000108296.7	417.74780	609.33980	-0.54460	3.00750	2.17450	HepG2	RPS3A
CWC25	ENSG00000108296.7	1157.71220	559.73610	1.04840	11.44830	10.01190	HepG2	SF3A3
CWC25	ENSG00000108296.7	536.95410	703.00630	-0.38870	3.49100	2.71750	HepG2	SLBP
CWC25	ENSG00000108296.7	603.83840	422.50230	0.51510	4.74410	4.16750	HepG2	SRSF1
CWC25	ENSG00000108296.7	431.72110	343.73590	0.32870	2.14820	1.64950	HepG2	SRSF9
CWC25	ENSG00000108296.7	548.12210	660.87790	-0.26990	1.93110	1.48300	HepG2	SSB
CWC25	ENSG00000108296.7	491.23930	379.78650	0.37110	2.37340	1.84740	HepG2	TAF15
CWC25	ENSG00000108296.7	627.24220	479.25550	0.38810	3.21090	2.57420	HepG2	UTP3
CWC25	ENSG00000108296.7	919.58660	545.94560	0.75210	15.21980	14.19390	HepG2	ZNF622
CWC25	ENSG00000108296.7	828.45480	677.60420	0.28990	2.33370	1.80500	K562	AGGF1
CWC25	ENSG00000108296.7	2236.87870	879.27360	1.34700	32.17070	30.36940	K562	AQR
CWC25	ENSG00000108296.7	1153.32310	938.87960	0.29670	3.03850	2.35920	K562	DDX47
CWC25	ENSG00000108296.7	585.47860	469.28760	0.31900	2.06940	1.37340	K562	EIF3G
CWC25	ENSG00000108296.7	587.25270	422.99650	0.47320	3.45350	2.54060	K562	EIF4A3
CWC25	ENSG00000108296.7	680.05460	439.90050	0.62840	7.29330	6.37440	K562	FXR1
CWC25	ENSG00000108296.7	781.92880	587.55150	0.41220	2.07690	1.33510	K562	NAA15
CWC25	ENSG00000108296.7	535.84690	771.83180	-0.52650	3.70870	2.74400	K562	PCBP3
CWC25	ENSG00000108296.7	435.38830	592.03260	-0.44340	3.24470	2.37250	K562	POLR2G
CWC25	ENSG00000108296.7	871.25820	451.75660	0.94750	11.38650	9.85700	K562	PRPF8
CWC25	ENSG00000108296.7	1714.48330	1309.69270	0.38840	3.43370	2.52650	K562	PUF60
CWC25	ENSG00000108296.7	936.40520	699.25730	0.42120	2.82770	2.27980	K562	PUS1
CWC25	ENSG00000108296.7	753.55800	538.62720	0.48430	3.92770	2.91260	K562	RBM22
CWC25	ENSG00000108296.7	965.92970	785.57670	0.29810	2.63130	1.83560	K562	SF3A3
CWC25	ENSG00000108296.7	615.03890	471.26960	0.38400	2.86920	1.99770	K562	SF3B4
CWC25	ENSG00000108296.7	732.25610	550.76680	0.41080	3.17250	2.41960	K562	SRSF1
CWC25	ENSG00000108296.7	368.27120	484.07800	-0.39450	2.56620	1.33820	K562	SSB
CWC25	ENSG00000108296.7	779.05090	593.80850	0.39160	3.20170	2.31780	K562	SYNCRIP
CWC25	ENSG00000108296.7	731.89720	557.37980	0.39290	2.55420	1.87250	K562	TARDBP
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for CWC25 is not available on ENCORE database.

10 RBPs can affect the splicing of CWC25 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	CWC25	ENSG00000108296.7	chr17	-	36966528	36966653	36965954	36966018	36966720	36966848	0.41800	0.00011	0.01133	included	HepG2	RBM22
SE	CWC25	ENSG00000108296.7	chr17	-	36966528	36966653	36965954	36966018	36966720	36966848	-0.18500	0.00509	0.07714	excluded	HepG2	U2AF1
SE	CWC25	ENSG00000108296.7	chr17	-	36962549	36962648	36959092	36959114	36963017	36963229	-0.17300	0.00045	0.01046	excluded	HepG2	U2AF1
SE	CWC25	ENSG00000108296.7	chr17	-	36966528	36966653	36965954	36966018	36966720	36966848	0.26800	0.00173	0.04806	included	K562	AKAP8L
SE	CWC25	ENSG00000108296.7	chr17	-	36962549	36962648	36959092	36959114	36963017	36963229	-0.14800	0.00000	0.00003	excluded	HepG2	U2AF2
SE	CWC25	ENSG00000108296.7	chr17	-	36966528	36966653	36965954	36966018	36966720	36966883	0.19000	0.00004	0.00074	included	K562	AQR
SE	CWC25	ENSG00000108296.7	chr17	-	36962800	36962857	36962549	36962648	36963017	36963229	0.06100	0.00102	0.01239	included	K562	AQR
SE	CWC25	ENSG00000108296.7	chr17	-	36971877	36971994	36971113	36971350	36977153	36977326	0.10700	0.00348	0.03456	included	K562	AQR
SE	CWC25	ENSG00000108296.7	chr17	-	36962549	36962648	36958952	36959114	36963017	36963229	-0.11500	0.00000	0.00005	excluded	K562	AQR
SE	CWC25	ENSG00000108296.7	chr17	-	36971877	36971994	36971174	36971350	36977153	36977326	0.12600	0.00034	0.07855	included	K562	PPIL4
SE	CWC25	ENSG00000108296.7	chr17	-	36962549	36962648	36959067	36959114	36963017	36963229	-0.11300	0.00180	0.04839	excluded	HepG2	SF3A3
SE	CWC25	ENSG00000108296.7	chr17	-	36966528	36966653	36965954	36966018	36966720	36966848	0.35000	0.00001	0.00445	included	K562	RBM22
SE	CWC25	ENSG00000108296.7	chr17	-	36966528	36966653	36965954	36966018	36966720	36966848	0.22200	0.00045	0.07231	included	K562	UPF1
SE	CWC25	ENSG00000108296.7	chr17	-	36962549	36962648	36959092	36959114	36963017	36963229	-0.14800	0.00202	0.03521	excluded	K562	U2AF2
SE	CWC25	ENSG00000108296.7	chr17	-	36966528	36966653	36965954	36966018	36966720	36966848	0.16400	0.00053	0.07259	included	K562	ZC3H8
A3SS	CWC25	ENSG00000108296.7	chr17	-	36958952	36959146	36958952	36959114	36962549	36962682	0.12600	0.00000	0.00000	longer	K562	AQR
A3SS	CWC25	ENSG00000108296.7	chr17	-	36962549	36962754	36962549	36962648	36963017	36963205	0.40100	0.00000	0.00000	longer	K562	AQR
A3SS	CWC25	ENSG00000108296.7	chr17	-	36966720	36966883	36966720	36966848	36969047	36969166	0.09400	0.00005	0.00049	longer	K562	AQR
A3SS	CWC25	ENSG00000108296.7	chr17	-	36965954	36966168	36965954	36966018	36966720	36966848	0.21400	0.00000	0.00000	longer	K562	AQR
A3SS	CWC25	ENSG00000108296.7	chr17	-	36966720	36966883	36966720	36966848	36969047	36969055	0.05500	0.00253	0.09899	longer	K562	PUS1
A5SS	CWC25	ENSG00000108296.7	chr17	-	36966528	36966848	36966720	36966848	36965954	36966018	0.31800	0.00005	0.01086	longer	K562	RBM22
A5SS	CWC25	ENSG00000108296.7	chr17	-	36966528	36966848	36966720	36966848	36965954	36966018	0.17100	0.00013	0.00330	longer	K562	AQR
A5SS	CWC25	ENSG00000108296.7	chr17	-	36966528	36966848	36966720	36966848	36965954	36966018	0.43700	0.00002	0.00359	longer	HepG2	RBM22
A5SS	CWC25	ENSG00000108296.7	chr17	-	36966528	36966848	36966720	36966848	36965954	36966018	0.28300	0.00074	0.06459	longer	K562	AKAP8L

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

CWC25

General Information

Functions

Localization

Domains (AlphaFold: CWC25)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for CWC25 is not avaliable on ENCORE database.

10 proteins are bound to CWC25 RNA:

eCLIP assay for CWC25 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for CWC25 is not available on ENCORE database.

41 RBPs can affect the gene expression of CWC25 :

The Knockdown/knockout RNA-Seq assay for CWC25 is not available on ENCORE database.

10 RBPs can affect the splicing of CWC25 :

The Knockdown/knockout RNA-Seq assay for CWC25 is not avaliable on ENCORE database.