COG2

General Information

Gene Name       : COG2
Gene ID             : ENSG00000135775.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: COG2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878COG2ENSG00000135775.1321.9418.7720.36ENCSR000AEF
HepG2COG2ENSG00000135775.1317.2925.3921.34ENCSR985KAT
K562COG2ENSG00000135775.1322.6222.5022.56ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for COG2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • COG2 RNA is bound by 15 proteins.  







eCLIP assay for COG2 is not avaliable on ENCORE database.





15 proteins are bound to COG2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1230807357230807424+3'-UTR,CDS,intron-Proximal3.364996.74268HepG2PRPF8
chr1230824306230824405+3'-UTR,CDS,intron-Proximal4.376004.62947HepG2AQR
chr1230827248230827328+3'-UTR,CDS,intron-Proximal4.430564.04372HepG2BCLAF1
chr1230805076230805161+3'-UTR,CDS,intron-Proximal3.178105.01844HepG2U2AF2
chr1230825759230825902+3'-UTR,CDS,intron-Proximal3.837633.11149HepG2G3BP1
chr1230827229230827314+3'-UTR,CDS,intron-Proximal3.922563.31827HepG2GRWD1
chr1230804422230804476+3'-UTR,CDS3.599413.27569HepG2BCLAF1
chr1230807266230807335+3'-UTR,CDS3.498593.27569HepG2BCLAF1
chr1230829035230829111+3'-UTR,CDS,intron-Proximal3.630113.87469HepG2BCLAF1
chr1230820838230820884+3'-UTR,CDS4.220393.02457HepG2BCLAF1
chr1230778386230778455+5'-UTR,CDS,intron-Proximal3.969123.60441HepG2GRWD1
chr1230796513230796610+5'-UTR,CDS,intron-Proximal5.204034.68690HepG2PRPF8
chr1230795211230795293+5'-UTR,CDS3.441896.58996HepG2GRWD1
chr1230796509230796577+5'-UTR,CDS,intron-Proximal4.073673.20743HepG2PPIG
chr1230798879230798965+5'-UTR,CDS,intron-Proximal4.256273.59236HepG2AQR
chr1230796502230796562+5'-UTR,CDS,intron-Proximal3.091763.08662K562YBX3
chr1230795304230795373+5'-UTR,CDS,intron-Proximal3.371873.90824K562YBX3
chr1230778250230778363+5'-UTR,CDS4.173448.28216K562DDX3X
chr1230778392230778469+5'-UTR,CDS,intron-Proximal3.320226.46344HepG2PRPF8
chr1230795313230795372+5'-UTR,CDS,intron-Proximal3.815863.34184HepG2GRWD1
chr1230778264230778300+5'-UTR5.058713.15149HepG2DDX3X
chr1230823562230823702+intron-Distal4.532275.07255HepG2KHSRP
chr1230807774230807833+intron-Distal4.832854.64001HepG2U2AF2
chr1230813085230813144+intron-Distal3.796253.04224HepG2SUGP2
chr1230801664230801772+intron-Distal3.638507.20487HepG2SUGP2
chr1230824308230824419+intron-Distal,intron-Proximal5.206366.04760K562AQR
chr1230806051230806100+intron-Distal4.634223.18269HepG2XPO5
chr1230811982230812120+intron-Distal3.996087.32475HepG2PTBP1
chr1230804946230805055+intron-Distal,intron-Proximal3.694063.26999K562KHSRP
chr1230801458230801544+intron-Distal3.184505.12506HepG2SUGP2
chr1230820511230820619+intron-Distal3.778043.45805K562KHSRP
chr1230802187230802284+intron-Distal4.092613.30440HepG2QKI
chr1230802098230802152+intron-Distal3.111273.10640HepG2SUGP2
chr1230801596230801715+intron-Distal3.944533.09122HepG2PTBP1
chr1230812008230812122+intron-Distal4.694204.31720HepG2MATR3
chr1230806993230807068+intron-Distal4.024338.36543HepG2U2AF2
chr1230811978230812061+intron-Distal5.082345.39854K562PTBP1
chr1230783134230783285+intron-Distal3.198294.89395HepG2SUGP2
chr1230811986230812106+intron-Distal3.919573.23532K562MATR3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for COG2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for COG2 is not available on ENCORE database.

  • 57 RBPs can affect the levels of COG2.  








The Knockdown/knockout RNA-Seq assay for COG2 is not available on ENCORE database.





57 RBPs can affect the gene expression of COG2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
COG2ENSG00000135775.91185.73980822.050400.528404.222103.07650HepG2ABCF1
COG2ENSG00000135775.9779.346301036.20770-0.411002.397001.89830HepG2AKAP1
COG2ENSG00000135775.91232.07000857.362700.523004.427903.44470HepG2ASCC1
COG2ENSG00000135775.9512.67150981.96530-0.937608.918107.17410HepG2CCAR1
COG2ENSG00000135775.91451.62390814.557500.8335010.960709.51520HepG2CIRBP
COG2ENSG00000135775.9870.36130698.263000.317703.288602.57430HepG2CKAP4
COG2ENSG00000135775.9586.49480747.41420-0.349802.126901.51510HepG2CPSF6
COG2ENSG00000135775.9594.04710401.425000.565304.365303.04580HepG2CSTF2
COG2ENSG00000135775.9786.19500645.924400.283402.616701.80300HepG2DDX19B
COG2ENSG00000135775.9923.40150648.872000.508904.848603.62710HepG2DDX24
COG2ENSG00000135775.9730.00290992.58250-0.443303.041702.39040HepG2DDX3X
COG2ENSG00000135775.9653.56290852.71050-0.383702.119601.57200HepG2DDX6
COG2ENSG00000135775.9951.85600668.179800.510406.596505.63580HepG2DKC1
COG2ENSG00000135775.9826.33410596.126400.471003.170702.18880HepG2EEF2
COG2ENSG00000135775.9900.35600626.264800.523605.247103.81330HepG2EIF3G
COG2ENSG00000135775.9982.74840712.092700.464703.670402.42330HepG2ESF1
COG2ENSG00000135775.9595.29160465.882300.353502.140601.44180HepG2FUBP3
COG2ENSG00000135775.91171.62300900.139100.380202.628201.76160HepG2G3BP2
COG2ENSG00000135775.9870.87950591.021100.559205.138104.29480HepG2HNRNPA1
COG2ENSG00000135775.9566.38550824.63010-0.542002.877001.88770HepG2MTPAP
COG2ENSG00000135775.9494.48570941.07420-0.9284010.295109.11320HepG2NCBP2
COG2ENSG00000135775.91029.85470716.932300.522404.705503.73860HepG2NSUN2
COG2ENSG00000135775.9392.31200586.00790-0.578902.616501.75810HepG2PABPC1
COG2ENSG00000135775.9580.34240838.03350-0.530103.924603.07590HepG2PABPC4
COG2ENSG00000135775.91021.38070854.613300.257102.263901.70460HepG2PCBP1
COG2ENSG00000135775.91059.58420807.910500.391104.459703.50220HepG2PRPF4
COG2ENSG00000135775.9710.83950492.912700.528103.647802.73500HepG2PRPF8
COG2ENSG00000135775.91051.31280840.558800.322702.684601.83840HepG2RBM15
COG2ENSG00000135775.91390.966901098.293000.340703.413902.85550HepG2RBM22
COG2ENSG00000135775.9615.50650854.73460-0.473704.045203.24320HepG2RBM25
COG2ENSG00000135775.91236.54070967.799500.353404.094303.45960HepG2NELFE
COG2ENSG00000135775.9672.22150472.516900.508503.517602.45400HepG2SERBP1
COG2ENSG00000135775.9897.608101240.46230-0.466707.009506.31270HepG2SRFBP1
COG2ENSG00000135775.9615.11520861.13020-0.485402.850101.83210HepG2SRSF3
COG2ENSG00000135775.91627.453901076.981500.5955012.5435011.60710HepG2SSB
COG2ENSG00000135775.9808.50240634.542200.349402.724202.22670HepG2TIAL1
COG2ENSG00000135775.9789.280901035.76600-0.392102.386701.61270HepG2UBE2L3
COG2ENSG00000135775.9623.89150823.71700-0.400903.880803.18980HepG2UTP3
COG2ENSG00000135775.9853.13080626.145800.446202.932302.18590HepG2XRN2
COG2ENSG00000135775.9959.72770797.308900.267402.569201.91770HepG2ZC3H8
COG2ENSG00000135775.91099.03150938.339100.228002.155601.65540HepG2ZNF622
COG2ENSG00000135775.9574.56290866.90440-0.593408.023007.12720K562AGGF1
COG2ENSG00000135775.9722.18060902.03580-0.320802.232901.64320K562AKAP8L
COG2ENSG00000135775.9210.68460359.42050-0.770602.690301.65490K562CCAR1
COG2ENSG00000135775.9753.099101036.05500-0.460204.977603.35440K562CCDC124
COG2ENSG00000135775.9616.84880787.38410-0.352202.572001.81470K562CPSF6
COG2ENSG00000135775.9447.68930576.51670-0.364902.379601.41570K562DDX3X
COG2ENSG00000135775.91551.073901157.262000.422506.420905.48560K562DDX47
COG2ENSG00000135775.9825.989801062.33930-0.363003.714702.90320K562EIF2S2
COG2ENSG00000135775.9833.33760650.338900.357602.852802.04450K562EIF3G
COG2ENSG00000135775.9917.29820626.362400.550306.840005.94940K562FXR1
COG2ENSG00000135775.9452.10440610.96890-0.434402.938202.32540K562HNRNPC
COG2ENSG00000135775.9616.52900832.89250-0.434002.519901.55540K562IGF2BP2
COG2ENSG00000135775.9535.03660733.80450-0.455803.476502.48980K562METAP2
COG2ENSG00000135775.9806.234801008.03830-0.322303.732502.88080K562NSUN2
COG2ENSG00000135775.9883.31210646.283100.450703.139702.34000K562PRPF8
COG2ENSG00000135775.9529.07000894.69700-0.757908.380607.48340K562PUS1
COG2ENSG00000135775.9677.72510871.64390-0.363003.228702.59600K562RBM15
COG2ENSG00000135775.9561.36250694.92200-0.307902.071101.33340K562SF3B4
COG2ENSG00000135775.9904.68440694.200300.382003.316802.41710K562SYNCRIP
COG2ENSG00000135775.9658.82390844.09280-0.357502.307101.65830K562TARDBP
COG2ENSG00000135775.9467.96280647.87820-0.469302.765901.67380K562U2AF1
COG2ENSG00000135775.9478.18680668.98070-0.484404.201703.21510K562U2AF2
COG2ENSG00000135775.9886.942301145.43370-0.369002.500601.36280K562UTP3
COG2ENSG00000135775.91177.60430951.098800.308103.703902.73460K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for COG2 is not available on ENCORE database.





6 RBPs can affect the splicing of COG2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECOG2ENSG00000135775.9chr1+230796503230796569230795209230795371230798886230798967-0.148000.002710.04609excludedK562SF3B4
SECOG2ENSG00000135775.9chr1+2308070042308071502308051012308052812308072612308073860.071000.000170.00277includedK562AQR
SECOG2ENSG00000135775.9chr1+230823816230823889230822680230822878230824165230824308-0.131000.000990.01215excludedK562AQR
SECOG2ENSG00000135775.9chr1+2308070042308071502308051012308052812308072612308073860.095000.000090.04581includedK562BUD13
SECOG2ENSG00000135775.9chr1+2308070042308071502308051012308052812308072612308073860.205000.000020.00115includedHepG2SF3A3
SECOG2ENSG00000135775.9chr1+2308070042308071502308051012308052812308072612308073860.059000.000640.03210includedK562HNRNPK
RICOG2ENSG00000135775.9chr1+2308051012308073862308051012308052812308072612308073860.086000.002430.02844includedHepG2NCBP2
RICOG2ENSG00000135775.9chr1+2308051012308073862308051012308052812308072612308073860.077000.001310.01694includedHepG2HNRNPK
MXECOG2ENSG00000135775.9chr1+230805101230805281230807004230807150230804421230804530230807261230807386-0.065000.000240.012732includedHepG2SF3A3
MXECOG2ENSG00000135775.9chr1+230805108230805281230807004230807150230804421230804530230807261230807386-0.221000.003160.079702includedHepG2SF3A3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for COG2 is not avaliable on ENCORE database.