CLCN2

General Information

Gene Name       : CLCN2
Gene ID             : ENSG00000114859.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CLCN2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CLCN2ENSG00000114859.150.560.740.65ENCSR000AEF
HepG2CLCN2ENSG00000114859.1514.118.3511.23ENCSR985KAT
K562CLCN2ENSG00000114859.157.366.306.83ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CLCN2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CLCN2 RNA is bound by 5 proteins.  







eCLIP assay for CLCN2 is not avaliable on ENCORE database.





5 proteins are bound to CLCN2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3184071363184071459-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.209356.82513HepG2PRPF8
chr3184070060184070131-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal5.5873811.12141HepG2PRPF8
chr3184070464184070528-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal5.253897.28294K562AQR
chr3184064047184064103-3'-UTR,intron-Distal,intron-Proximal5.655355.06516K562PUM2
chr3184070482184070535-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.7826510.32997HepG2PRPF8
chr3184071042184071086-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal5.100897.35950HepG2PPIG
chr3184076715184076770-5'-UTR,CDS,intron-Distal,intron-Proximal5.159258.72621HepG2PRPF8
chr3184079218184079261-5'-UTR,CDS,intron-Distal4.849946.91190HepG2PPIG
chr3184074800184074833-5'-UTR,CDS,intron-Distal,intron-Proximal4.308413.79199HepG2PPIG
chr3184079225184079339-5'-UTR,CDS,intron-Distal,intron-Proximal3.988049.09300HepG2DDX3X
chr3184072083184072101-CDS,intron-Distal4.163953.82843HepG2PPIG
chr3184072336184072355-CDS,intron-Distal4.474705.18660HepG2PPIG
chr3184076717184076753-intron-Distal,intron-Proximal4.800453.62536K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CLCN2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CLCN2 is not available on ENCORE database.

  • 67 RBPs can affect the levels of CLCN2.  








The Knockdown/knockout RNA-Seq assay for CLCN2 is not available on ENCORE database.





67 RBPs can affect the gene expression of CLCN2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CLCN2ENSG00000114859.10423.54730217.939200.958508.428107.45250HepG2BOP1
CLCN2ENSG00000114859.10135.47220198.06980-0.548002.070601.39670HepG2CALR
CLCN2ENSG00000114859.10440.65820293.895100.584305.472704.59710HepG2CKAP4
CLCN2ENSG00000114859.10291.05860200.076800.540702.470201.81540HepG2CPSF6
CLCN2ENSG00000114859.10263.02440187.792100.486002.432301.48090HepG2YBX3
CLCN2ENSG00000114859.10108.54650179.25240-0.723702.619901.31640HepG2CSTF2T
CLCN2ENSG00000114859.10347.66400271.848200.354802.220101.46700HepG2DDX19B
CLCN2ENSG00000114859.10279.67750192.956100.535402.593801.93340HepG2DDX21
CLCN2ENSG00000114859.10394.00540269.618000.547203.213302.13020HepG2DDX5
CLCN2ENSG00000114859.10393.77870281.206500.485703.235802.51320HepG2DKC1
CLCN2ENSG00000114859.10261.24730182.291800.519102.546101.51110HepG2EIF3G
CLCN2ENSG00000114859.10424.65150277.661200.612903.377902.67330HepG2EIF4A3
CLCN2ENSG00000114859.10210.77030287.24630-0.446602.132801.40050HepG2EWSR1
CLCN2ENSG00000114859.10204.80820308.74320-0.592102.315801.60760HepG2FIP1L1
CLCN2ENSG00000114859.10476.91230276.051500.788705.912204.59910HepG2G3BP2
CLCN2ENSG00000114859.10242.97320152.780500.669203.195402.22420HepG2GEMIN5
CLCN2ENSG00000114859.10361.53370226.793600.672702.309201.72110HepG2GPKOW
CLCN2ENSG00000114859.10259.46230186.169800.478802.037101.47270HepG2HNRNPA1
CLCN2ENSG00000114859.10645.27990263.381101.2927016.5548014.99610HepG2HNRNPK
CLCN2ENSG00000114859.10361.58900264.192300.452702.053501.46290HepG2IGF2BP2
CLCN2ENSG00000114859.10386.05950265.781600.538502.366401.44910HepG2KHSRP
CLCN2ENSG00000114859.10523.50660366.557700.514102.684401.86670HepG2LARP4
CLCN2ENSG00000114859.10446.60890280.387800.671504.312203.49690HepG2MAGOH
CLCN2ENSG00000114859.10471.26020281.934200.741102.412201.82090HepG2MATR3
CLCN2ENSG00000114859.10504.53660288.556700.806005.951205.03900HepG2NCBP2
CLCN2ENSG00000114859.10310.89040194.345800.677703.204602.08860HepG2PCBP2
CLCN2ENSG00000114859.10248.46780183.475500.437402.090901.44290HepG2PPIL4
CLCN2ENSG00000114859.10238.72420330.25760-0.468202.722502.17820HepG2PTBP1
CLCN2ENSG00000114859.10630.64050288.315601.1291015.6434014.37990HepG2PUF60
CLCN2ENSG00000114859.10407.39420306.077000.412403.280002.64560HepG2PUM1
CLCN2ENSG00000114859.10246.25920357.66020-0.538403.247402.57820HepG2QKI
CLCN2ENSG00000114859.10217.41720357.16130-0.716105.480804.32340HepG2RBM15
CLCN2ENSG00000114859.10279.54050427.02860-0.611304.846904.20960HepG2RBM22
CLCN2ENSG00000114859.10223.46350337.83730-0.596303.454902.70480HepG2RPLP0
CLCN2ENSG00000114859.10275.54400184.279700.580302.282401.42260HepG2RPS10
CLCN2ENSG00000114859.10233.51820166.990200.483701.907401.38900HepG2RPS19
CLCN2ENSG00000114859.10224.97110123.899700.860503.986303.02540HepG2RPS3A
CLCN2ENSG00000114859.10287.77520183.193600.651504.523203.73300HepG2SAFB2
CLCN2ENSG00000114859.10562.63290419.134200.424701.870701.31380HepG2SF3A3
CLCN2ENSG00000114859.10432.07440343.826600.329501.846301.34690HepG2SF3B4
CLCN2ENSG00000114859.10279.87690213.637300.389501.966101.40890HepG2SMN1
CLCN2ENSG00000114859.10426.52830238.361200.839404.467703.46460HepG2SNRNP70
CLCN2ENSG00000114859.10258.13670482.31320-0.9018011.0552010.23440HepG2SRFBP1
CLCN2ENSG00000114859.10221.17930358.88630-0.698305.313604.71250HepG2SRSF1
CLCN2ENSG00000114859.10145.81910230.51820-0.660702.504901.55630HepG2SRSF3
CLCN2ENSG00000114859.10505.59090284.690300.8285010.456009.34350HepG2SRSF5
CLCN2ENSG00000114859.10584.49230418.762400.481004.690304.05810HepG2SSB
CLCN2ENSG00000114859.10432.66990323.753600.418303.201502.54230HepG2SUCLG1
CLCN2ENSG00000114859.10178.33740322.59710-0.855106.676505.87120HepG2TAF15
CLCN2ENSG00000114859.10330.01230210.980200.645303.644102.82670HepG2TARDBP
CLCN2ENSG00000114859.10203.06360296.40570-0.545603.116302.23470HepG2TIA1
CLCN2ENSG00000114859.10289.24040199.893700.532902.860502.35360HepG2TIAL1
CLCN2ENSG00000114859.10351.90490201.669900.803107.432506.58470HepG2TRIM56
CLCN2ENSG00000114859.10444.74350281.700200.658705.282604.03370HepG2TUFM
CLCN2ENSG00000114859.10395.82600264.096800.583703.326702.64340HepG2U2AF1
CLCN2ENSG00000114859.10407.96660199.455801.032302.760801.77300HepG2U2AF2
CLCN2ENSG00000114859.10421.70470298.193800.499902.459001.67360HepG2UBE2L3
CLCN2ENSG00000114859.10372.81660230.141500.695802.633401.92650HepG2XRN2
CLCN2ENSG00000114859.10289.45050196.382500.559502.402401.42690K562CSTF2
CLCN2ENSG00000114859.10551.93820418.911400.397803.041001.76970K562DDX21
CLCN2ENSG00000114859.10199.17990359.07610-0.850207.744806.63080K562EIF2S2
CLCN2ENSG00000114859.10173.81620101.595000.774603.841002.91290K562EIF3G
CLCN2ENSG00000114859.10706.07210539.769600.387402.915501.95220K562EIF4G2
CLCN2ENSG00000114859.10149.43060236.04090-0.659603.238602.31710K562FIP1L1
CLCN2ENSG00000114859.1027.1891095.43390-1.811505.268904.22180K562G3BP2
CLCN2ENSG00000114859.10442.09100322.846200.453403.075001.86940K562GLRX3
CLCN2ENSG00000114859.10211.12950320.02260-0.600003.288402.42370K562HSPD1
CLCN2ENSG00000114859.10499.65890377.170100.405603.152202.35940K562NSUN2
CLCN2ENSG00000114859.10452.77890588.90820-0.379202.384701.62840K562PUF60
CLCN2ENSG00000114859.10144.08610281.15700-0.964405.339004.61700K562PUS1
CLCN2ENSG00000114859.10380.85790273.945400.475302.955002.34580K562RBM15
CLCN2ENSG00000114859.10335.53020207.035100.696503.389602.48250K562RPS19
CLCN2ENSG00000114859.10498.66460372.110900.422202.039901.33240K562SF3A3
CLCN2ENSG00000114859.10161.4250099.106500.703703.053802.15440K562SF3B4
CLCN2ENSG00000114859.10181.79350257.89110-0.504502.500301.72180K562SYNCRIP
CLCN2ENSG00000114859.10255.89450150.144500.769103.895403.04920K562TARDBP
CLCN2ENSG00000114859.10333.71680233.023500.518002.417501.54550K562TIAL1
CLCN2ENSG00000114859.10358.11910247.701100.531702.861401.89700K562TRIM56
CLCN2ENSG00000114859.1049.7142095.43750-0.940903.151702.29520K562U2AF2
CLCN2ENSG00000114859.10173.44010274.20310-0.660803.800901.63620K562ZNF800
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CLCN2 is not available on ENCORE database.





5 RBPs can affect the splicing of CLCN2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSCLCN2ENSG00000114859.10chr3-1840723351840725021840723351840724461840726911840727610.416000.001240.08323longerHepG2SF3A3
A3SSCLCN2ENSG00000114859.10chr3-1840723351840725021840723351840724461840726911840727610.742000.001280.06215longerK562SF3B4
A3SSCLCN2ENSG00000114859.10chr3-1840702301840703961840702301840702841840705241840705980.128000.019080.09159longerK562AQR
A3SSCLCN2ENSG00000114859.10chr3-1840723351840725021840723351840724461840726911840727610.481000.005760.03271longerK562AQR
A3SSCLCN2ENSG00000114859.10chr3-1840647221840648581840647221840648091840698001840699050.116000.002870.01776longerK562AQR
A3SSCLCN2ENSG00000114859.10chr3-1840734811840737241840734811840735661840747801840748080.209000.002110.01352longerK562AQR
A3SSCLCN2ENSG00000114859.10chr3-1840734811840737241840734811840735661840747801840748820.264000.000180.01174longerK562PUS1
A3SSCLCN2ENSG00000114859.10chr3-1840734811840737241840734811840735661840747801840748820.298000.000790.03272longerHepG2U2AF1
MXECLCN2ENSG00000114859.10chr3-1840698001840699051840700801840701191840647221840648091840702301840702840.148000.005640.078751includedHepG2U2AF1
MXECLCN2ENSG00000114859.10chr3-184069800184069905184070080184070119184064722184064809184070230184070284-0.246000.001440.047422includedHepG2SF3A3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CLCN2 is not avaliable on ENCORE database.