C5orf22

General Information

Gene Name       : C5orf22
Gene ID             : ENSG00000082213.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: C5orf22)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878C5orf22ENSG00000082213.1722.6620.8521.76ENCSR000AEF
HepG2C5orf22ENSG00000082213.178.9816.6512.81ENCSR985KAT
K562C5orf22ENSG00000082213.1727.7933.4330.61ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for C5orf22 is not avaliable on ENCORE database.



Proteins bound to RNA
  • C5orf22 RNA is bound by 7 proteins.  







eCLIP assay for C5orf22 is not avaliable on ENCORE database.





7 proteins are bound to C5orf22 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr53155286631552915+3'-UTR,CDS,intron-Proximal4.367623.77802HepG2U2AF2
chr53155412031554138+3'-UTR4.163613.11728K562FAM120A
chr53155306531553112+3'-UTR4.338517.87748K562PUM2
chr53155294131553044+3'-UTR,CDS3.773043.43253K562YBX3
chr53155392731553990+3'-UTR3.100464.14964K562UPF1
chr53153241931532575+5'-UTR,CDS3.910416.97927K562DDX3X
chr53154125031541386+intron-Distal,intron-Proximal3.896563.45805K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for C5orf22 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for C5orf22 is not available on ENCORE database.

  • 52 RBPs can affect the levels of C5orf22.  








The Knockdown/knockout RNA-Seq assay for C5orf22 is not available on ENCORE database.





52 RBPs can affect the gene expression of C5orf22 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
C5orf22ENSG00000082213.131335.99980722.548500.886709.526208.60400HepG2AKAP1
C5orf22ENSG00000082213.13565.37530770.57510-0.446704.549103.70680HepG2AUH
C5orf22ENSG00000082213.13457.98530763.46020-0.737306.974305.92210HepG2CPSF6
C5orf22ENSG00000082213.13379.71960571.60030-0.590103.888303.19230HepG2EIF2S1
C5orf22ENSG00000082213.13483.26200363.588500.410402.270501.44460HepG2EIF3D
C5orf22ENSG00000082213.13672.01710884.69590-0.396703.543802.87690HepG2ETF1
C5orf22ENSG00000082213.13300.29670591.22070-0.977309.239208.05980HepG2G3BP1
C5orf22ENSG00000082213.13468.13440568.37770-0.279901.884701.37460HepG2HNRNPU
C5orf22ENSG00000082213.13565.72870705.40690-0.318302.129501.48830HepG2IGF2BP1
C5orf22ENSG00000082213.13439.21670580.58150-0.402603.820502.97290HepG2ILF2
C5orf22ENSG00000082213.131143.61950637.497000.843009.723608.51180HepG2MAGOH
C5orf22ENSG00000082213.13889.90280641.081900.473003.008702.35400HepG2MATR3
C5orf22ENSG00000082213.13582.53450380.552600.614102.767001.71440HepG2METAP2
C5orf22ENSG00000082213.13454.94230584.05820-0.360402.191701.64100HepG2PCBP1
C5orf22ENSG00000082213.13371.08460506.95010-0.450103.523302.70160HepG2PPIL4
C5orf22ENSG00000082213.131288.63970574.075401.1664022.6594021.17230HepG2PUF60
C5orf22ENSG00000082213.13818.96150609.373200.426405.001904.25220HepG2PUM1
C5orf22ENSG00000082213.13395.79390608.94870-0.621606.168205.18010HepG2PUM2
C5orf22ENSG00000082213.13822.48650643.698900.353502.166001.60150HepG2QKI
C5orf22ENSG00000082213.131111.35640489.905801.181609.744408.47420HepG2RAVER1
C5orf22ENSG00000082213.13515.98690661.38490-0.358202.024901.54660HepG2NELFE
C5orf22ENSG00000082213.13520.13710353.755300.556004.231603.48630HepG2RPS19
C5orf22ENSG00000082213.13404.33920506.17410-0.324102.262201.67020HepG2SAFB2
C5orf22ENSG00000082213.13525.23120355.099600.564603.850902.74000HepG2SERBP1
C5orf22ENSG00000082213.131003.09440683.080900.554203.433002.67930HepG2SF3A3
C5orf22ENSG00000082213.13348.86930817.55730-1.2286017.9996016.36730HepG2SF3B1
C5orf22ENSG00000082213.13795.48780618.784400.362302.733902.14540HepG2SF3B4
C5orf22ENSG00000082213.13978.36470645.837700.599105.459104.85140HepG2SRSF1
C5orf22ENSG00000082213.13814.55640644.614600.337502.920202.28480HepG2SUCLG1
C5orf22ENSG00000082213.13295.49350557.21870-0.9151013.2827012.17870HepG2TRIM56
C5orf22ENSG00000082213.13865.52820589.775900.553304.647403.84390HepG2U2AF1
C5orf22ENSG00000082213.13813.81480593.555000.455202.453601.66930HepG2UBE2L3
C5orf22ENSG00000082213.13749.71790481.706100.638103.627702.16050HepG2XRCC5
C5orf22ENSG00000082213.13746.05030538.742600.469602.396501.41160HepG2XRCC6
C5orf22ENSG00000082213.131031.789701346.12530-0.383704.916904.19600K562AGGF1
C5orf22ENSG00000082213.131132.007101400.69460-0.307302.327601.72720K562AKAP8L
C5orf22ENSG00000082213.132253.670801849.891300.284701.964801.45430K562AQR
C5orf22ENSG00000082213.131484.621601827.13170-0.299502.829902.03870K562CPSF6
C5orf22ENSG00000082213.13655.58620974.46670-0.571808.516106.20810K562DDX27
C5orf22ENSG00000082213.132660.885102126.242700.323503.702202.96330K562DDX47
C5orf22ENSG00000082213.131855.034401507.309100.299403.365702.38690K562DKC1
C5orf22ENSG00000082213.131443.99190834.952100.7902011.605109.88850K562EIF4A3
C5orf22ENSG00000082213.131180.38170868.308500.442905.356704.55280K562FXR1
C5orf22ENSG00000082213.13744.800601053.88970-0.500805.102203.09100K562G3BP1
C5orf22ENSG00000082213.131512.64930951.044400.669405.620004.53160K562G3BP2
C5orf22ENSG00000082213.131426.867301910.13350-0.420804.251403.31750K562GRSF1
C5orf22ENSG00000082213.131442.795001101.026000.389902.907601.64130K562HNRNPK
C5orf22ENSG00000082213.131770.347301158.512500.611708.746607.20710K562MAGOH
C5orf22ENSG00000082213.131673.522402133.19990-0.350102.074401.36770K562PPIG
C5orf22ENSG00000082213.131404.291101125.551700.319102.838202.16660K562PTBP1
C5orf22ENSG00000082213.133618.359402622.219300.464405.573104.41710K562PUF60
C5orf22ENSG00000082213.132173.899902732.82240-0.330104.020502.85980K562PUM2
C5orf22ENSG00000082213.13966.097801389.17480-0.524005.447804.71760K562PUS1
C5orf22ENSG00000082213.13843.798901135.85330-0.428803.425302.19030K562NELFE
C5orf22ENSG00000082213.131190.89610896.833300.409002.863702.03200K562RPS19
C5orf22ENSG00000082213.131248.13150989.292800.335203.193402.27390K562SF3B4
C5orf22ENSG00000082213.131092.39120852.569600.357502.349101.41620K562SUPV3L1
C5orf22ENSG00000082213.131612.134801138.703300.501503.242602.35410K562SYNCRIP
C5orf22ENSG00000082213.13699.417701116.45950-0.674703.683202.56190K562TRIM56
C5orf22ENSG00000082213.131502.85520952.388900.6580010.648909.06850K562U2AF2
C5orf22ENSG00000082213.131372.870001724.69400-0.329104.378903.49530K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for C5orf22 is not available on ENCORE database.





6 RBPs can affect the splicing of C5orf22 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEC5orf22ENSG00000082213.13chr5+3154859631548794315457773154581931551399315515390.128000.000080.00270includedK562SRSF1
SEC5orf22ENSG00000082213.13chr5+315485963154879431545777315458193155139931551539-0.264000.002620.03146excludedHepG2U2AF2
SEC5orf22ENSG00000082213.13chr5+315485963154879431545777315458193155139931551539-0.169000.000820.05016excludedHepG2AKAP1
SEC5orf22ENSG00000082213.13chr5+315457523154581931541387315415093155139931551539-0.073000.004810.04503excludedK562AQR
SEC5orf22ENSG00000082213.13chr5+3154859631548794315457773154581931551399315515390.237000.003920.08793includedHepG2SF3A3
A3SSC5orf22ENSG00000082213.13chr5+3155137231551539315513993155153931545706315458190.103000.000090.00076longerK562AQR
A3SSC5orf22ENSG00000082213.13chr5+315383663153879631538590315387963153585031536000-0.307000.000140.08645shorterK562FMR1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for C5orf22 is not avaliable on ENCORE database.