C21orf59

General Information

Gene Name       : C21orf59
Gene ID             :
Essential Gene : No

Functions

Localization

Domains (AlphaFold: C21orf59)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for C21orf59 is not avaliable on ENCORE database.



Proteins bound to RNA
  • C21orf59 RNA is bound by 22 proteins.  







eCLIP assay for C21orf59 is not avaliable on ENCORE database.





22 proteins are bound to C21orf59 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr213397648133976510-3'-UTR,CDS,intron-Distal4.352638.94008K562ZNF622
chr213397546633975528-3'-UTR,CDS,intron-Distal,intron-Proximal3.271485.09919K562DDX55
chr213397547033975526-3'-UTR,CDS,intron-Distal,intron-Proximal3.4473916.22459K562ZNF622
chr213397412533974265-3'-UTR,CDS,intron-Distal4.0001720.74060K562UCHL5
chr213397457933974649-3'-UTR,CDS,intron-Distal,intron-Proximal3.0623410.94089K562ZNF800
chr213397459633974679-3'-UTR,CDS,intron-Distal,intron-Proximal3.038844.65451K562MTPAP
chr213397420833974260-3'-UTR,CDS,intron-Distal4.512854.91614HepG2GRWD1
chr213397464533974677-3'-UTR,CDS,intron-Distal,intron-Proximal3.4531613.16579K562UCHL5
chr213397647233976594-3'-UTR,CDS,intron-Distal,intron-Proximal3.7343516.85915HepG2BCLAF1
chr213397644533976512-3'-UTR,CDS,intron-Distal,intron-Proximal4.548635.35719HepG2GRWD1
chr213397645933976541-3'-UTR,CDS,intron-Distal,intron-Proximal3.767033.04123K562LIN28B
chr213397415633974277-3'-UTR,CDS,intron-Distal3.5240915.06273K562PUM1
chr213397453833974629-3'-UTR,CDS,intron-Distal,intron-Proximal4.0949217.04905HepG2PRPF8
chr213397464533974676-3'-UTR,CDS,intron-Distal,intron-Proximal3.295647.64415K562ZNF622
chr213397557733975597-3'-UTR,CDS,intron-Distal,intron-Proximal3.674039.79481K562UCHL5
chr213397554133975593-3'-UTR,CDS,intron-Distal,intron-Proximal4.8757410.68247K562PABPC4
chr213397550933975590-3'-UTR,CDS,intron-Distal,intron-Proximal3.784715.31167HepG2GRWD1
chr213397420033974249-3'-UTR,CDS,intron-Distal3.453346.00087K562YBX3
chr213397413933974283-3'-UTR,CDS,intron-Distal3.1570517.05410K562ZNF622
chr213397405833974108-3'-UTR,intron-Distal,intron-Proximal6.01639400.00000K562PABPC4
chr213397536633975444-3'-UTR,CDS,intron-Distal,intron-Proximal4.530824.58968K562PRPF8
chr213397548233975515-3'-UTR,CDS,intron-Distal,intron-Proximal3.761623.87469HepG2BCLAF1
chr213397549933975575-3'-UTR,CDS,intron-Distal,intron-Proximal4.5715421.96565K562UCHL5
chr213397547033975499-3'-UTR,CDS,intron-Distal,intron-Proximal3.9699413.97212K562UCHL5
chr213397406233974099-3'-UTR,intron-Distal,intron-Proximal4.483404.77252K562ZNF622
chr213398459633984708-5'-UTR,intron-Distal,intron-Proximal3.2986310.37505K562DDX3X
chr213398460333984689-5'-UTR,intron-Distal,intron-Proximal3.933715.22400HepG2DDX3X
chr213398470833984882-5'-UTR,intron-Distal,intron-Proximal3.184229.07003K562DDX3X
chr213398460133984653-5'-UTR,intron-Distal,intron-Proximal3.226403.34822K562RBM15
chr213398214733982166-CDS,intron-Distal,intron-Proximal3.202373.31144K562TRA2A
chr213397651833976576-CDS,intron-Distal,intron-Proximal5.1010029.02939K562ZNF622
chr213397996633979979-CDS,intron-Distal4.4139020.11017K562UCHL5
chr213397995833979970-CDS,intron-Distal,intron-Proximal3.205183.05460HepG2PPIG
chr213398214633982209-CDS,intron-Distal,intron-Proximal3.5699618.23281K562ZNF622
chr213398001333980026-CDS,intron-Distal3.152517.52395K562GRWD1
chr213397653733976591-CDS,intron-Distal,intron-Proximal4.588136.18872K562TRA2A
chr213397996033980027-CDS,intron-Distal,intron-Proximal3.975157.17294K562TRA2A
chr213397996733980013-CDS,intron-Distal3.7953913.11289K562GRWD1
chr213397654533976572-CDS,intron-Distal,intron-Proximal3.9925939.34387K562UCHL5
chr213397658933976594-CDS,intron-Distal,intron-Proximal4.2755428.47992K562UCHL5
chr213397652533976573-CDS,intron-Distal,intron-Proximal3.9876915.51579K562GRWD1
chr213397995733980027-CDS,intron-Distal,intron-Proximal3.220875.63844K562SRSF1
chr213398001333980026-CDS,intron-Distal3.3795212.23735K562ZNF622
chr213398214733982173-CDS,intron-Distal,intron-Proximal4.728643.91772K562TARDBP
chr213397657333976586-CDS,intron-Distal,intron-Proximal3.5136010.26919K562GRWD1
chr213397995833979966-CDS,intron-Distal,intron-Proximal3.9230723.98410K562UCHL5
chr213398214633982228-CDS,intron-Distal,intron-Proximal3.4727211.78960K562PUM1
chr213397995733979967-CDS,intron-Distal,intron-Proximal3.402276.20035HepG2BCLAF1
chr213397657933976595-CDS,intron-Distal,intron-Proximal3.0037610.66926K562PUM1
chr213397995833979998-CDS,intron-Distal,intron-Proximal3.3524923.02802K562ZNF622
chr213397651233976577-CDS,intron-Distal,intron-Proximal3.641026.59473HepG2GRWD1
chr213397995733980028-CDS,intron-Distal,intron-Proximal4.050576.18146K562TARDBP
chr213397652133976545-CDS,intron-Distal,intron-Proximal3.6080511.53978K562UCHL5
chr213398214433982223-CDS,intron-Distal,intron-Proximal3.135856.09950HepG2BCLAF1
chr213398214733982181-CDS,intron-Distal,intron-Proximal4.2868220.41228K562UCHL5
chr213397998633980027-CDS,intron-Distal,intron-Proximal3.101678.98636K562PUM1
chr213397657233976589-CDS,intron-Distal,intron-Proximal4.4557939.62421K562UCHL5
chr213397658633976593-CDS,intron-Distal,intron-Proximal3.044547.82632K562GRWD1
chr213398218133982221-CDS,intron-Distal4.3604011.27765K562UCHL5
chr213398001233980026-CDS,intron-Distal3.6889017.08805K562UCHL5
chr213397652133976594-CDS,intron-Distal,intron-Proximal3.316388.05447HepG2PPIG
chr213397657633976593-CDS,intron-Distal,intron-Proximal3.4622219.16702K562ZNF622
chr213397652633976594-CDS,intron-Distal,intron-Proximal3.3584910.35201K562ZNF800
chr213397997933980012-CDS,intron-Distal3.9469730.25432K562UCHL5
chr213397995633979981-CDS,intron-Distal,intron-Proximal3.861264.71116K562CPSF6
chr213397863633978731-intron-Distal3.896103.41738HepG2PTBP1
chr213398437233984415-intron-Distal4.540078.52787K562AQR
chr213397859233978671-intron-Distal4.120923.29248HepG2SUGP2
chr213397865033978720-intron-Distal4.169353.42734K562PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for C21orf59 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for C21orf59 is not available on ENCORE database.

  • 53 RBPs can affect the levels of C21orf59.  








The Knockdown/knockout RNA-Seq assay for C21orf59 is not available on ENCORE database.





53 RBPs can affect the gene expression of C21orf59 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
C21orf59ENSG00000159079.14789.23540602.535200.389304.135303.42030HepG2ACO1
C21orf59ENSG00000159079.141271.46690721.666100.817008.073507.21620HepG2AKAP1
C21orf59ENSG00000159079.14860.95660573.479400.586103.589702.52440HepG2BCCIP
C21orf59ENSG00000159079.14664.87250469.853700.500802.260901.57410HepG2CNOT7
C21orf59ENSG00000159079.14314.41650532.04280-0.758906.160205.16650HepG2CPSF6
C21orf59ENSG00000159079.141018.33640823.667700.306002.710602.07320HepG2CELF1
C21orf59ENSG00000159079.14671.82170885.72110-0.398804.158703.27870HepG2DAZAP1
C21orf59ENSG00000159079.141271.42370691.279000.8790010.620009.46920HepG2DDX3X
C21orf59ENSG00000159079.14834.47900593.875800.490603.028302.38510HepG2DDX6
C21orf59ENSG00000159079.14552.47180375.148800.558303.898802.83660HepG2EIF3D
C21orf59ENSG00000159079.14453.63760603.08000-0.410802.191901.61870HepG2GPKOW
C21orf59ENSG00000159079.14864.31510640.338300.432602.564701.95480HepG2MATR3
C21orf59ENSG00000159079.14966.31070655.411700.560004.355603.56840HepG2NCBP2
C21orf59ENSG00000159079.14469.10570838.36940-0.8377010.811709.73690HepG2PUF60
C21orf59ENSG00000159079.14990.80280506.129200.969006.688005.61830HepG2RAVER1
C21orf59ENSG00000159079.141148.57570815.601400.493804.318103.70840HepG2RBM22
C21orf59ENSG00000159079.14667.68500803.81470-0.267702.409101.74840HepG2SLBP
C21orf59ENSG00000159079.14954.02100633.837500.589803.292302.43670HepG2SNRNP70
C21orf59ENSG00000159079.14469.38790572.40830-0.286301.958501.36220HepG2SRSF7
C21orf59ENSG00000159079.14707.45140410.159700.786306.323004.60250HepG2STIP1
C21orf59ENSG00000159079.14525.01730331.541500.663104.675203.68340HepG2UCHL5
C21orf59ENSG00000159079.14606.69880483.138700.328402.593301.91350HepG2UPF1
C21orf59ENSG00000159079.14651.48270496.616200.391503.308602.17420HepG2UTP18
C21orf59ENSG00000159079.141720.627602829.18320-0.7175011.018009.96160K562AQR
C21orf59ENSG00000159079.142398.680002024.257300.244702.757801.84580K562ATP5C1
C21orf59ENSG00000159079.14836.320701261.82630-0.593403.537502.55110K562BOP1
C21orf59ENSG00000159079.141889.652302262.17470-0.259602.799601.68890K562CPEB4
C21orf59ENSG00000159079.14874.418501341.60240-0.617606.714705.48470K562CPSF6
C21orf59ENSG00000159079.143120.182103719.96390-0.253702.962701.95440K562CELF1
C21orf59ENSG00000159079.142514.130702075.828700.276303.628202.60710K562DKC1
C21orf59ENSG00000159079.14900.078301404.27640-0.641708.127306.72360K562EIF4A3
C21orf59ENSG00000159079.142432.623903025.12630-0.314504.474003.29240K562EIF4G2
C21orf59ENSG00000159079.14863.654701365.20540-0.660607.668406.20130K562FMR1
C21orf59ENSG00000159079.14856.293001157.20280-0.434503.251202.25330K562FTO
C21orf59ENSG00000159079.141303.132301766.24770-0.438706.102904.45070K562GLRX3
C21orf59ENSG00000159079.14980.326801280.83540-0.385803.254402.39500K562GPKOW
C21orf59ENSG00000159079.142148.527902584.52410-0.266602.109301.44360K562GRSF1
C21orf59ENSG00000159079.14746.646301179.58100-0.659808.487807.49310K562HNRNPC
C21orf59ENSG00000159079.14804.051201093.84350-0.444002.551901.65900K562KRR1
C21orf59ENSG00000159079.142605.815503224.42760-0.307302.817901.67540K562MSI2
C21orf59ENSG00000159079.141326.097301856.99560-0.485809.196907.81010K562MTPAP
C21orf59ENSG00000159079.141711.828202063.19650-0.269304.502503.57770K562NSUN2
C21orf59ENSG00000159079.141286.764802127.10930-0.725102.330001.43650K562PABPN1
C21orf59ENSG00000159079.142762.695003300.59590-0.256702.005601.30990K562PUF60
C21orf59ENSG00000159079.142756.733503439.77930-0.319404.844603.56140K562PUM2
C21orf59ENSG00000159079.142314.744401913.086400.274902.271901.77040K562PUS1
C21orf59ENSG00000159079.142132.671301864.153300.194001.815701.31740K562RBM15
C21orf59ENSG00000159079.141296.966502035.98580-0.650609.815208.34930K562SF3A3
C21orf59ENSG00000159079.14920.058801218.35580-0.405102.672201.71460K562SF3B1
C21orf59ENSG00000159079.141754.803001416.181600.309202.802402.09230K562SRSF1
C21orf59ENSG00000159079.14781.271801031.08240-0.400302.550001.57920K562SUPV3L1
C21orf59ENSG00000159079.14710.739901017.27650-0.517304.158802.99090K562TIAL1
C21orf59ENSG00000159079.14823.346301081.08040-0.392903.229502.18900K562TRIM56
C21orf59ENSG00000159079.14735.226201091.29860-0.569805.277303.82920K562UCHL5
C21orf59ENSG00000159079.141580.730102187.65830-0.468809.384608.15760K562UPF1
C21orf59ENSG00000159079.141356.615001871.89820-0.464505.636404.36750K562WDR3
C21orf59ENSG00000159079.141537.311001946.63890-0.340605.525904.37160K562WDR43
C21orf59ENSG00000159079.142706.147803352.09050-0.308803.049701.68690K562WRN
C21orf59ENSG00000159079.142482.507203187.15420-0.360503.688602.66550K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for C21orf59 is not available on ENCORE database.





11 RBPs can affect the splicing of C21orf59 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEC21orf59ENSG00000159079.14chr21-339745813397467733973976339742833397547033975602-0.134000.000000.00000excludedK562SRSF1
SEC21orf59ENSG00000159079.14chr21-339745813397467733973976339742833397547033975602-0.061000.000000.00126excludedK562TIA1
SEC21orf59ENSG00000159079.14chr21-339745813397467733973976339742833397547033975602-0.063000.001580.09374excludedHepG2DDX3X
SEC21orf59ENSG00000159079.14chr21-339745813397467733973976339742833397547033975602-0.089000.000000.00000excludedK562PUS1
SEC21orf59ENSG00000159079.14chr21-339745813397467733973976339742833397547033975602-0.091000.000250.02085excludedHepG2NCBP2
SEC21orf59ENSG00000159079.14chr21-339745813397467733973976339742833397547033975602-0.155000.000000.00000excludedHepG2SRSF1
SEC21orf59ENSG00000159079.14chr21-339745813397473333974094339742833397547033975602-0.112000.000050.00156excludedK562U2AF2
SEC21orf59ENSG00000159079.14chr21-339745813397467733974094339742833397547033975602-0.236000.000000.00000excludedK562TARDBP
SEC21orf59ENSG00000159079.14chr21-339745813397473333974094339742833397547033975602-0.081000.006040.08059excludedK562HNRNPC
RIC21orf59ENSG00000159079.14chr21-339739763397560233973976339742833397547033975602-0.467000.000000.00000excludedK562SRSF1
RIC21orf59ENSG00000159079.14chr21-339739763397560233973976339742833397547033975602-0.411000.000080.01966excludedK562TIA1
RIC21orf59ENSG00000159079.14chr21-339739763397560233973976339742833397547033975602-0.495000.000040.00186excludedHepG2SRSF1
RIC21orf59ENSG00000159079.14chr21-339739763397560233973976339742833397547033975602-0.243000.003290.04312excludedK562U2AF2
RIC21orf59ENSG00000159079.14chr21-3397397633975602339739763397428333975470339756020.223000.000280.00212includedK562AQR
RIC21orf59ENSG00000159079.14chr21-339739763397560233973976339742833397547033975602-0.647000.000000.00000excludedK562TARDBP
RIC21orf59ENSG00000159079.14chr21-339739763397560233973976339742833397547033975602-0.521000.000000.00000excludedK562PTBP1
MXEC21orf59ENSG00000159079.14chr21-33974581339746773397547033975602339739763397428333976434339765930.147000.000000.000221includedK562TARDBP
MXEC21orf59ENSG00000159079.14chr21-3397547033975530339764343397659333973976339742833397995833980026-0.211000.000000.000002includedK562TARDBP
MXEC21orf59ENSG00000159079.14chr21-33974581339746773397547033975602339739763397428333976434339765930.083000.000610.037141includedK562PHF6

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for C21orf59 is not avaliable on ENCORE database.