USPL1

General Information

Gene Name       : USPL1
Gene ID             : ENSG00000132952.11
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: USPL1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878USPL1ENSG00000132952.1116.5715.8116.19ENCSR000AEF
HepG2USPL1ENSG00000132952.117.1013.3710.23ENCSR985KAT
K562USPL1ENSG00000132952.1110.4411.3410.89ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for USPL1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • USPL1 RNA is bound by 9 proteins.  







eCLIP assay for USPL1 is not avaliable on ENCORE database.





9 proteins are bound to USPL1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr133119206831192192+5'-UTR3.612907.11310HepG2NCBP2
chr133119211331192182+5'-UTR4.136113.98353K562RBM15
chr133119591731195954+CDS3.365155.15776HepG2BCLAF1
chr133120531031205374+CDS3.102513.40321HepG2GRWD1
chr133120497031205008+CDS,intron-Proximal3.337624.61799HepG2BCLAF1
chr133123292931232987+CDS4.238726.65960HepG2BCLAF1
chr133123292231232961+CDS3.986273.26547HepG2HLTF
chr133123217831232232+CDS5.284047.24744K562PUM2
chr133120513231205183+CDS4.111846.65960HepG2BCLAF1
chr133123251131232540+CDS4.636094.34038HepG2BCLAF1
chr133120500831205059+CDS4.593119.30195HepG2BCLAF1
chr133121361331213676+intron-Distal4.499144.64001HepG2U2AF2
chr133119571231195802+intron-Distal,intron-Proximal3.519723.53952HepG2KHSRP
chr133119571731195813+intron-Distal,intron-Proximal3.9413710.80633K562KHSRP
chr133122846831228556+intron-Distal4.374823.91475K562PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for USPL1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for USPL1 is not available on ENCORE database.

  • 52 RBPs can affect the levels of USPL1.  








The Knockdown/knockout RNA-Seq assay for USPL1 is not available on ENCORE database.





52 RBPs can affect the gene expression of USPL1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
USPL1ENSG00000132952.7986.25350787.256400.325003.161702.43440HepG2AUH
USPL1ENSG00000132952.7397.08820595.00650-0.583404.537903.79300HepG2BOP1
USPL1ENSG00000132952.71007.36870518.105300.9592023.6909022.17560HepG2CKAP4
USPL1ENSG00000132952.7558.44460747.30860-0.420303.961003.21710HepG2CELF1
USPL1ENSG00000132952.7470.16950734.71340-0.644005.084204.25890HepG2DDX3X
USPL1ENSG00000132952.7369.05430502.76140-0.446003.402802.62820HepG2DNAJC21
USPL1ENSG00000132952.7455.64010606.72440-0.413102.231701.69330HepG2EIF2S1
USPL1ENSG00000132952.71259.54840792.759200.6679011.7317010.24490HepG2EIF4G1
USPL1ENSG00000132952.7688.68600380.845400.854509.823808.38920HepG2FUBP3
USPL1ENSG00000132952.7510.88620676.50850-0.405102.355301.71490HepG2FXR1
USPL1ENSG00000132952.7417.02410619.17790-0.570203.496302.78320HepG2GPKOW
USPL1ENSG00000132952.7379.58880507.57790-0.419202.515201.89600HepG2HNRNPA1
USPL1ENSG00000132952.7345.90950564.58370-0.706805.845204.86540HepG2HNRNPC
USPL1ENSG00000132952.7934.65360635.462500.556504.855303.94990HepG2HNRNPK
USPL1ENSG00000132952.7309.44960560.85120-0.8579012.2759011.07510HepG2HNRNPU
USPL1ENSG00000132952.7449.72740637.90160-0.504303.378302.63830HepG2IGF2BP2
USPL1ENSG00000132952.71025.06450578.408200.825506.430904.90210HepG2PCBP2
USPL1ENSG00000132952.7405.60750760.69080-0.9072011.9768010.85620HepG2PUF60
USPL1ENSG00000132952.7848.60420649.147900.386403.675902.97880HepG2RECQL
USPL1ENSG00000132952.7491.90690767.27300-0.641404.252703.26050HepG2RPS3A
USPL1ENSG00000132952.7629.66200361.693100.799706.969905.78680HepG2RRP9
USPL1ENSG00000132952.72100.61470672.256601.6436027.4616025.28550HepG2SF3A3
USPL1ENSG00000132952.7768.54950584.854400.394002.544401.86550HepG2SF3B1
USPL1ENSG00000132952.7425.86020582.46290-0.451804.437103.65660HepG2SMN1
USPL1ENSG00000132952.7470.32690650.75850-0.468502.053401.38470HepG2SNRNP70
USPL1ENSG00000132952.71170.72310853.271100.456206.722206.03600HepG2SRFBP1
USPL1ENSG00000132952.7884.22810629.348500.490502.827401.81380HepG2SRSF3
USPL1ENSG00000132952.7577.31320751.01700-0.379503.761603.05310HepG2SRSF5
USPL1ENSG00000132952.7398.59750503.33280-0.336602.481801.81890HepG2SRSF7
USPL1ENSG00000132952.7322.61740471.64150-0.547902.315801.68990HepG2SUPV3L1
USPL1ENSG00000132952.7840.32070611.729500.457904.587703.89370HepG2TAF15
USPL1ENSG00000132952.7889.62720562.134100.662208.172306.74680HepG2TIA1
USPL1ENSG00000132952.7544.95610743.08870-0.447403.786502.74920HepG2TUFM
USPL1ENSG00000132952.7453.58020596.18910-0.394403.432402.66870HepG2UPF1
USPL1ENSG00000132952.7761.03330517.974900.555007.389506.37890HepG2ZC3H8
USPL1ENSG00000132952.7837.23430655.693500.352503.930303.30920HepG2ZNF622
USPL1ENSG00000132952.74571.86640856.841402.41560109.58890106.47560K562AQR
USPL1ENSG00000132952.7507.24060661.96580-0.384102.225301.44840K562BOP1
USPL1ENSG00000132952.7511.06320703.82860-0.461703.835502.91270K562CPSF6
USPL1ENSG00000132952.7586.28980428.932900.450803.040102.08170K562EFTUD2
USPL1ENSG00000132952.7497.78570622.25280-0.322002.313401.64700K562EIF2S2
USPL1ENSG00000132952.7623.52080459.302300.440902.500501.52340K562EIF3D
USPL1ENSG00000132952.7533.80920705.27260-0.401902.751101.90530K562FIP1L1
USPL1ENSG00000132952.7565.02610433.693900.381502.723402.12250K562FXR1
USPL1ENSG00000132952.7846.01540487.897200.794003.471002.66140K562G3BP2
USPL1ENSG00000132952.7331.07850461.54610-0.479302.917702.30710K562HNRNPC
USPL1ENSG00000132952.7764.69030956.20790-0.322402.090601.39600K562HSPD1
USPL1ENSG00000132952.7417.54380569.55690-0.447902.266201.36430K562IGF2BP2
USPL1ENSG00000132952.7758.01200532.574300.509104.191102.98130K562PCBP2
USPL1ENSG00000132952.7634.86920800.61570-0.334702.103301.39170K562PPIG
USPL1ENSG00000132952.71115.30200417.399901.4178025.4632023.17890K562PRPF8
USPL1ENSG00000132952.7724.62380557.262700.378802.211301.71470K562PUS1
USPL1ENSG00000132952.7636.13090425.201500.581104.020203.03210K562RPS19
USPL1ENSG00000132952.7824.25700620.258400.410103.634102.70690K562SF3A3
USPL1ENSG00000132952.7749.67900453.245700.725902.776301.54450K562SNRNP200
USPL1ENSG00000132952.7645.98510416.553100.632906.305405.05980K562SYNCRIP
USPL1ENSG00000132952.7404.14920576.98660-0.513603.609402.79790K562TARDBP
USPL1ENSG00000132952.7420.59950556.56960-0.404102.742601.92920K562TIA1
USPL1ENSG00000132952.7744.28520473.201800.653305.222203.62060K562U2AF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for USPL1 is not available on ENCORE database.





9 RBPs can affect the splicing of USPL1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEUSPL1ENSG00000132952.7chr13+311952093119537631191919311921933119590031196029-0.329000.000920.07249excludedHepG2G3BP1
SEUSPL1ENSG00000132952.7chr13+311952093119537631191919311921933119590031196029-0.621000.000000.00000excludedK562IGF2BP2
SEUSPL1ENSG00000132952.7chr13+311952093119537631191919311921933119590031196029-0.425000.000000.00015excludedK562SRSF1
SEUSPL1ENSG00000132952.7chr13+311952093119537631191919311921933119590031196029-0.410000.000110.05194excludedK562KHSRP
SEUSPL1ENSG00000132952.7chr13+3119520931195376311919193119219331195900311960290.419000.000340.04450includedHepG2PCBP2
SEUSPL1ENSG00000132952.7chr13+3119520931195358311919193119219331195900311960290.364000.002440.06107includedHepG2SF3A3
SEUSPL1ENSG00000132952.7chr13+311952093119537631191919311921933119590031196029-0.497000.000000.00012excludedHepG2IGF2BP3
SEUSPL1ENSG00000132952.7chr13+3119381531193877311918293119219331195900311960290.386000.001900.09969includedK562HNRNPUL1
SEUSPL1ENSG00000132952.7chr13+3119520931195376311919193119219331195900311960290.359000.000400.02229includedHepG2SF3B4
MXEUSPL1ENSG00000132952.7chr13+31204971312056113121188031211994311959003119602931216764312168940.227000.005630.068901includedHepG2HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for USPL1 is not avaliable on ENCORE database.