TPRKB

General Information

Gene Name       : TPRKB
Gene ID             : ENSG00000144034.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TPRKB)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TPRKBENSG00000144034.1443.9540.7442.34ENCSR000AEF
HepG2TPRKBENSG00000144034.1442.1272.6957.41ENCSR985KAT
K562TPRKBENSG00000144034.1479.1374.9677.04ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TPRKB is not avaliable on ENCORE database.



Proteins bound to RNA
  • TPRKB RNA is bound by 5 proteins.  







eCLIP assay for TPRKB is not avaliable on ENCORE database.





5 proteins are bound to TPRKB RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr27396169473961720-5'-UTR,CDS,intron-Distal,intron-Proximal4.3979112.22508K562DDX3X
chr27396442873964471-5'-UTR,intron-Distal,intron-Proximal4.478448.45138K562DDX3X
chr27396432573964453-5'-UTR,intron-Distal4.244424.52089HepG2NCBP2
chr27395931873959341-CDS,intron-Distal4.035654.31428K562YBX3
chr27395923273959295-CDS,intron-Distal,intron-Proximal4.768383.62536K562AQR
chr27395782873957864-CDS,intron-Distal,intron-Proximal4.312045.13745K562YBX3
chr27395934173959393-CDS,intron-Distal3.354184.31744K562YBX3
chr27395928873959318-CDS,intron-Distal,intron-Proximal4.700856.92025K562YBX3
chr27396167673961694-CDS,intron-Distal5.3351512.67847K562DDX3X
chr27396162873961676-CDS,intron-Distal,intron-Proximal4.4214213.01397K562DDX3X
chr27396017573960245-intron-Distal4.474754.17759HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TPRKB is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TPRKB is not available on ENCORE database.

  • 64 RBPs can affect the levels of TPRKB.  








The Knockdown/knockout RNA-Seq assay for TPRKB is not available on ENCORE database.





64 RBPs can affect the gene expression of TPRKB :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TPRKBENSG00000144034.10279.56030445.27640-0.671504.340403.36530HepG2ASCC1
TPRKBENSG00000144034.10370.84530525.51070-0.502904.410303.57940HepG2AUH
TPRKBENSG00000144034.10287.31480423.03980-0.558203.148802.32550HepG2CIRBP
TPRKBENSG00000144034.10310.64930474.67110-0.611604.121703.29800HepG2CPSF6
TPRKBENSG00000144034.10270.86180399.47430-0.560502.857101.73380HepG2CPSF7
TPRKBENSG00000144034.10384.59260630.65040-0.713508.930707.89990HepG2CELF1
TPRKBENSG00000144034.10513.00770678.19740-0.402704.271703.38270HepG2DAZAP1
TPRKBENSG00000144034.10275.73380539.02120-0.967105.671304.28730HepG2DDX59
TPRKBENSG00000144034.10212.83120442.78870-1.056908.329707.31260HepG2DDX6
TPRKBENSG00000144034.10211.72310294.79050-0.477502.614001.92600HepG2DNAJC21
TPRKBENSG00000144034.10227.03290292.22760-0.364201.926701.36470HepG2DNAJC2
TPRKBENSG00000144034.10155.91770425.71710-1.4491014.6106013.31630HepG2EIF2S1
TPRKBENSG00000144034.10296.27290470.49330-0.667203.926603.16920HepG2EIF4A3
TPRKBENSG00000144034.10353.72790640.87640-0.857409.036807.60110HepG2EIF4G2
TPRKBENSG00000144034.10500.57590603.37460-0.269501.819901.31140HepG2ETF1
TPRKBENSG00000144034.10293.27570440.32990-0.586303.414802.67930HepG2G3BP1
TPRKBENSG00000144034.10341.79370467.41270-0.451602.346501.53010HepG2G3BP2
TPRKBENSG00000144034.10487.62010623.23780-0.354002.778001.84230HepG2HNRNPA2B1
TPRKBENSG00000144034.10235.44050331.05510-0.491702.329501.68840HepG2HNRNPC
TPRKBENSG00000144034.10307.78150492.55730-0.678402.082901.45460HepG2HNRNPF
TPRKBENSG00000144034.10302.80010445.77760-0.558003.316602.55390HepG2HNRNPK
TPRKBENSG00000144034.10446.02270617.81430-0.470105.049904.16160HepG2HNRNPL
TPRKBENSG00000144034.10345.86330513.51590-0.570202.827502.19190HepG2HNRNPLL
TPRKBENSG00000144034.10279.58950485.04080-0.794803.186702.41400HepG2IGF2BP1
TPRKBENSG00000144034.10248.06730447.60030-0.851506.596705.59550HepG2IGF2BP2
TPRKBENSG00000144034.10283.45200435.28690-0.618903.807602.97130HepG2PABPC4
TPRKBENSG00000144034.10432.39690641.92860-0.570101.906701.39860HepG2PUF60
TPRKBENSG00000144034.10468.37840681.40520-0.540807.136706.27490HepG2PUM1
TPRKBENSG00000144034.10421.05340680.92630-0.693507.842706.73920HepG2PUM2
TPRKBENSG00000144034.10724.10730338.202301.098207.670006.52960HepG2RAVER1
TPRKBENSG00000144034.10218.59820332.18900-0.603702.510701.60830HepG2RPS10
TPRKBENSG00000144034.10809.46780393.084401.042007.311106.17690HepG2SF3A3
TPRKBENSG00000144034.10455.97100615.44710-0.432704.366403.51370HepG2SLBP
TPRKBENSG00000144034.10472.60540569.58820-0.269301.910001.47070HepG2SRFBP1
TPRKBENSG00000144034.10603.46050402.395900.584505.964305.33530HepG2SRSF1
TPRKBENSG00000144034.10406.19960633.77460-0.641807.795906.81570HepG2SRSF5
TPRKBENSG00000144034.10277.12540483.87810-0.804103.291702.54150HepG2SRSF7
TPRKBENSG00000144034.10228.29070327.37740-0.520103.465902.86340HepG2SRSF9
TPRKBENSG00000144034.10554.35430720.80750-0.378802.293301.71730HepG2SUCLG1
TPRKBENSG00000144034.10214.57740330.76300-0.624303.710502.63340HepG2SUPT6H
TPRKBENSG00000144034.10334.06550500.45940-0.583103.899403.05530HepG2TARDBP
TPRKBENSG00000144034.10195.96010319.50420-0.705303.852903.28410HepG2TIAL1
TPRKBENSG00000144034.10253.29810322.41400-0.348101.897201.41270HepG2TRIM56
TPRKBENSG00000144034.10450.71130627.08750-0.476503.292702.33350HepG2TUFM
TPRKBENSG00000144034.10450.44580663.72960-0.559203.670102.69940HepG2UBE2L3
TPRKBENSG00000144034.10226.41290348.60600-0.622604.824703.94360HepG2UPF1
TPRKBENSG00000144034.10544.50040336.565000.693907.472106.56630HepG2UTP3
TPRKBENSG00000144034.10552.44020371.917800.570703.037001.92480HepG2XRCC6
TPRKBENSG00000144034.10622.95960821.72850-0.399504.064402.88460K562BCLAF1
TPRKBENSG00000144034.10478.59820623.40350-0.381402.609001.58560K562CSTF2
TPRKBENSG00000144034.10401.65870527.57870-0.393402.508401.51760K562DDX3X
TPRKBENSG00000144034.10453.23210579.52570-0.354602.707501.51760K562EIF2S1
TPRKBENSG00000144034.10523.52020712.96930-0.445603.723302.22180K562EXOSC5
TPRKBENSG00000144034.10751.04380573.225700.389703.512802.84310K562FXR1
TPRKBENSG00000144034.10371.83790618.47520-0.734005.152004.36040K562HNRNPC
TPRKBENSG00000144034.10547.47950750.19820-0.454503.771701.56460K562HNRNPH1
TPRKBENSG00000144034.101131.30610700.684000.691103.950002.82310K562HNRNPM
TPRKBENSG00000144034.101914.293301155.089700.7287010.067908.57850K562HSPD1
TPRKBENSG00000144034.102205.371401631.919300.434404.376602.47440K562NOL12
TPRKBENSG00000144034.10742.67750927.66920-0.320903.616702.77640K562NSUN2
TPRKBENSG00000144034.10684.49160906.89370-0.405902.518901.72610K562PCBP3
TPRKBENSG00000144034.101197.54790967.050600.308302.005301.31080K562PPIG
TPRKBENSG00000144034.101017.01480539.686400.914009.741108.32790K562PRPF8
TPRKBENSG00000144034.10948.00700764.811200.309702.519201.70540K562SF3B4
TPRKBENSG00000144034.10571.12920738.15810-0.370102.448801.46810K562SRSF5
TPRKBENSG00000144034.10374.97640533.34890-0.508302.786101.84650K562TIAL1
TPRKBENSG00000144034.10401.59490566.41360-0.496103.192502.16010K562TRIM56
TPRKBENSG00000144034.10755.10370983.62770-0.381404.171103.30660K562UPF1
TPRKBENSG00000144034.10671.17060841.65840-0.326602.339501.53350K562WDR3
TPRKBENSG00000144034.101045.90980875.232300.256902.194901.43460K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TPRKB is not available on ENCORE database.





9 RBPs can affect the splicing of TPRKB :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETPRKBENSG00000144034.10chr2-739597107395982773959289739594127396155573961718-0.134000.000000.00000excludedK562PRPF8
SETPRKBENSG00000144034.10chr2-739597107395982773959289739594127396155573961718-0.068000.000020.00045excludedK562AQR
SETPRKBENSG00000144034.10chr2-739597107395982773959289739594127396155573961718-0.122000.000000.00001excludedK562EFTUD2
SETPRKBENSG00000144034.10chr2-739615557396165573959289739594127396442873964485-0.065000.001080.03988excludedK562TARDBP
SETPRKBENSG00000144034.10chr2-7395971073959827739592897395941273961555739617150.162000.000000.00000includedK562HNRNPC
A3SSTPRKBENSG00000144034.10chr2-7395695673957205739569567395715673957686739578630.095000.000000.00000longerK562AQR
A5SSTPRKBENSG00000144034.10chr2-7396155573961718739616547396171873959196739594120.154000.000000.00000longerK562AQR
A5SSTPRKBENSG00000144034.10chr2-739615557396171873961654739617187395928973959412-0.200000.002000.06499shorterHepG2U2AF2
A5SSTPRKBENSG00000144034.10chr2-739615557396171873961654739617187395928973959412-0.210000.000020.00218shorterHepG2SRSF1
A5SSTPRKBENSG00000144034.10chr2-739615557396171873961654739617187395928973959412-0.146000.000290.02076shorterK562U2AF2
A5SSTPRKBENSG00000144034.10chr2-739615557396171873961654739617187395928973959412-0.212000.000100.01763shorterHepG2QKI
A5SSTPRKBENSG00000144034.10chr2-7396155573961655739616547396165573959289739594120.137000.000420.07301longerK562SF3B1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TPRKB is not avaliable on ENCORE database.