TMBIM4

General Information

Gene Name       : TMBIM4
Gene ID             : ENSG00000155957.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TMBIM4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TMBIM4ENSG00000155957.1724.5941.3732.98ENCSR000AEF
HepG2TMBIM4ENSG00000155957.1730.8942.4236.66ENCSR985KAT
K562TMBIM4ENSG00000155957.1750.6433.4242.03ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TMBIM4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TMBIM4 RNA is bound by 7 proteins.  







eCLIP assay for TMBIM4 is not avaliable on ENCORE database.





7 proteins are bound to TMBIM4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr126653967066539739-3'-UTR,CDS,intron-Distal,intron-Proximal5.235847.80881K562PUM2
chr126654714566547231-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.556155.06399K562DDX3X
chr126656368366563771-5'-UTR,CDS,intron-Distal,intron-Proximal5.5843319.47813K562DDX3X
chr126656314766563192-5'-UTR,intron-Distal,intron-Proximal3.901373.28989K562RBM15
chr126656363666563683-5'-UTR,CDS,intron-Distal3.8935513.37398K562DDX3X
chr126656363466563678-5'-UTR,CDS,intron-Distal4.804286.75419HepG2DDX3X
chr126656311066563147-5'-UTR,CDS,intron-Distal,intron-Proximal4.111663.48187K562RBM15
chr126656367866563773-5'-UTR,CDS,intron-Distal,intron-Proximal4.119555.84843HepG2DDX3X
chr126655428466554381-intron-Distal4.421355.19823K562KHSRP
chr126656353266563613-intron-Distal4.272624.48994K562RBM15
chr126655760266557683-intron-Distal3.315323.84025HepG2SUGP2
chr126655436066554424-intron-Distal4.365874.94603K562CSTF2T
chr126653951566539601-intron-Distal,intron-Proximal4.267565.02888K562KHSRP
chr126655235766552428-intron-Distal3.858883.61897HepG2HNRNPC
chr126653393066534108-intron-Distal5.1607410.38845K562KHSRP
chr126653565866535740-intron-Distal3.739363.06150K562KHSRP
chr126653797066538034-intron-Distal3.477534.36650HepG2SUGP2
chr126655859166558629-intron-Distal3.728783.16028HepG2SUGP2
chr126653278666532904-intron-Distal,intron-Proximal4.199063.90026K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TMBIM4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TMBIM4 is not available on ENCORE database.

  • 77 RBPs can affect the levels of TMBIM4.  








The Knockdown/knockout RNA-Seq assay for TMBIM4 is not available on ENCORE database.





77 RBPs can affect the gene expression of TMBIM4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TMBIM4ENSG00000155957.121190.09190651.072900.870108.862207.96990HepG2AKAP1
TMBIM4ENSG00000155957.12452.77850352.762200.360002.397001.67770HepG2AKAP8L
TMBIM4ENSG00000155957.12722.42270538.718800.423202.601001.83880HepG2ASCC1
TMBIM4ENSG00000155957.1299.97130155.05170-0.633202.123101.59360HepG2BOP1
TMBIM4ENSG00000155957.12297.76120189.866300.649104.019303.11270HepG2CALR
TMBIM4ENSG00000155957.12851.77240511.816500.734707.225406.02010HepG2CIRBP
TMBIM4ENSG00000155957.12219.08970351.03340-0.680105.901204.99620HepG2CKAP4
TMBIM4ENSG00000155957.12598.33770372.239300.684603.596302.71820HepG2CNOT7
TMBIM4ENSG00000155957.12230.99880142.353200.698303.333102.58620HepG2CPSF6
TMBIM4ENSG00000155957.12409.18210275.807500.569003.520102.76270HepG2DDX21
TMBIM4ENSG00000155957.121221.83790623.701400.9700012.4395011.20340HepG2DDX3X
TMBIM4ENSG00000155957.12316.85170219.820000.527402.743201.45140HepG2DDX47
TMBIM4ENSG00000155957.12456.03340335.928400.440903.133602.41980HepG2DKC1
TMBIM4ENSG00000155957.12333.33350234.096000.509802.237701.40720HepG2EEF2
TMBIM4ENSG00000155957.12360.66140554.16590-0.619703.278702.53260HepG2EIF4B
TMBIM4ENSG00000155957.12429.78950574.24060-0.418002.299401.66600HepG2FXR1
TMBIM4ENSG00000155957.12402.75760532.73350-0.403502.043701.46900HepG2G3BP1
TMBIM4ENSG00000155957.12530.07050316.390800.744406.069505.07110HepG2HNRNPC
TMBIM4ENSG00000155957.12383.62460539.34490-0.491503.005902.27920HepG2HNRNPK
TMBIM4ENSG00000155957.12248.70170154.014200.691303.302202.62040HepG2HNRNPLL
TMBIM4ENSG00000155957.12426.56770574.44070-0.429402.337401.73290HepG2MAGOH
TMBIM4ENSG00000155957.12356.14030577.66850-0.697804.755703.94590HepG2MATR3
TMBIM4ENSG00000155957.12287.29150212.350300.436002.018801.32260HepG2MSI2
TMBIM4ENSG00000155957.12156.31640526.62640-1.7523023.4824021.43670HepG2PABPC4
TMBIM4ENSG00000155957.12511.09590357.642400.515004.798704.02940HepG2PUS1
TMBIM4ENSG00000155957.12483.49510323.096000.581402.316901.66840HepG2RAVER1
TMBIM4ENSG00000155957.12379.98390248.258500.614004.382103.33370HepG2RBM15
TMBIM4ENSG00000155957.12721.89580511.200600.497804.822304.18630HepG2RBM22
TMBIM4ENSG00000155957.12436.00600593.49230-0.444903.554602.95740HepG2NELFE
TMBIM4ENSG00000155957.12231.53270332.45020-0.521902.799002.11270HepG2RPLP0
TMBIM4ENSG00000155957.1299.86490152.45520-0.610301.908201.31490HepG2SF3B1
TMBIM4ENSG00000155957.12391.08590555.20640-0.505504.376303.65840HepG2SF3B4
TMBIM4ENSG00000155957.12576.65870329.943500.805405.867904.43580HepG2SMNDC1
TMBIM4ENSG00000155957.12692.82190579.522200.257501.717901.32030HepG2SRSF1
TMBIM4ENSG00000155957.12588.12300480.929300.290201.995201.45270HepG2SRSF5
TMBIM4ENSG00000155957.12803.88300501.312500.6812010.336209.46640HepG2SSB
TMBIM4ENSG00000155957.12651.37770546.942600.252001.828901.30380HepG2SUCLG1
TMBIM4ENSG00000155957.12557.11120360.599600.627504.144603.34130HepG2SUPV3L1
TMBIM4ENSG00000155957.12394.60420241.711000.707004.206603.01220HepG2TFIP11
TMBIM4ENSG00000155957.12471.58780334.802700.494102.362901.35850HepG2XPO5
TMBIM4ENSG00000155957.12233.04510168.652600.466502.324401.70190HepG2ZC3H8
TMBIM4ENSG00000155957.12203.57800274.79390-0.432802.396501.87660HepG2ZNF622
TMBIM4ENSG00000155957.12267.20170359.64170-0.428602.452501.91270K562AGGF1
TMBIM4ENSG00000155957.12174.44010278.45800-0.674704.858402.81420K562AKAP1
TMBIM4ENSG00000155957.12242.51070374.22160-0.625804.016303.22740K562AKAP8L
TMBIM4ENSG00000155957.12276.10070685.28900-1.3115016.6174015.33880K562AQR
TMBIM4ENSG00000155957.12298.87340392.64500-0.393702.294201.47010K562ATP5C1
TMBIM4ENSG00000155957.12233.10790329.59100-0.499702.283801.41270K562BCLAF1
TMBIM4ENSG00000155957.12157.48670241.53040-0.617002.728301.30960K562CKAP4
TMBIM4ENSG00000155957.12169.92720250.04400-0.557302.647101.61580K562CSTF2
TMBIM4ENSG00000155957.12564.02030832.42150-0.561605.373504.00970K562CELF1
TMBIM4ENSG00000155957.12308.87730402.70110-0.382702.275501.49210K562DKC1
TMBIM4ENSG00000155957.12224.74980309.81910-0.463102.925201.67500K562EIF2S1
TMBIM4ENSG00000155957.12578.48110438.234200.400503.126202.36880K562EIF2S2
TMBIM4ENSG00000155957.12185.28150294.71540-0.669604.184703.17680K562EIF4A3
TMBIM4ENSG00000155957.12130.66150205.93630-0.656403.218101.83850K562EXOSC5
TMBIM4ENSG00000155957.12407.94440306.488100.412402.450701.87470K562FXR1
TMBIM4ENSG00000155957.12284.93470455.34770-0.676305.595603.47580K562G3BP1
TMBIM4ENSG00000155957.12161.51660235.33370-0.543002.680101.55560K562GLRX3
TMBIM4ENSG00000155957.12118.94420223.40510-0.909403.462101.43820K562HNRNPA0
TMBIM4ENSG00000155957.12290.62360449.47400-0.629105.419104.15600K562HNRNPU
TMBIM4ENSG00000155957.12430.31290300.814600.516402.925702.10870K562HSPD1
TMBIM4ENSG00000155957.12278.30310476.35480-0.775405.231603.63840K562IGF2BP2
TMBIM4ENSG00000155957.12359.56990484.48190-0.430202.797201.59820K562IGF2BP3
TMBIM4ENSG00000155957.12298.25220397.14930-0.413102.272101.53390K562KIF1C
TMBIM4ENSG00000155957.12374.80960499.51380-0.414402.718701.80490K562MATR3
TMBIM4ENSG00000155957.12195.97890274.89630-0.488202.634701.90340K562NSUN2
TMBIM4ENSG00000155957.12169.24280278.47790-0.718503.929701.74900K562PABPC4
TMBIM4ENSG00000155957.12360.88030489.32020-0.439302.994701.58890K562PCBP1
TMBIM4ENSG00000155957.12159.48900445.34290-1.4815018.0711015.46300K562PCBP2
TMBIM4ENSG00000155957.1297.03490261.94980-1.4327010.701309.06830K562PCBP3
TMBIM4ENSG00000155957.1289.37430200.92010-1.168707.584506.28310K562POLR2G
TMBIM4ENSG00000155957.12115.46400221.50430-0.939903.658801.56120K562PPIL4
TMBIM4ENSG00000155957.12369.05910486.31500-0.398002.586701.94120K562PTBP1
TMBIM4ENSG00000155957.12250.53070371.13860-0.567002.793802.24860K562PUS1
TMBIM4ENSG00000155957.12299.17470466.27010-0.640204.973403.80740K562RBM22
TMBIM4ENSG00000155957.12155.28300249.88970-0.686403.637602.08530K562RBM25
TMBIM4ENSG00000155957.12131.24810264.39900-1.010403.484901.71130K562RBM39
TMBIM4ENSG00000155957.12162.42510271.27570-0.740004.761003.71560K562SF3A3
TMBIM4ENSG00000155957.12105.42240273.93650-1.3777013.2945011.32420K562SF3B4
TMBIM4ENSG00000155957.12297.04410450.28890-0.600204.184802.84900K562SRSF5
TMBIM4ENSG00000155957.12180.86480274.59700-0.602403.056001.37820K562TBRG4
TMBIM4ENSG00000155957.12349.55090465.42330-0.413002.566801.78190K562TIA1
TMBIM4ENSG00000155957.12333.42150456.76890-0.454102.638801.57630K562TRA2A
TMBIM4ENSG00000155957.12119.84010184.54130-0.622802.394001.52360K562TRIM56
TMBIM4ENSG00000155957.12146.45420255.37840-0.802204.223102.81430K562U2AF1
TMBIM4ENSG00000155957.12148.78840263.72260-0.825805.635404.48860K562U2AF2
TMBIM4ENSG00000155957.12212.10380376.28230-0.827003.679002.12060K562UTP18
TMBIM4ENSG00000155957.12185.98920259.36910-0.479802.587601.76640K562WDR43
TMBIM4ENSG00000155957.12580.36260772.07410-0.411802.870301.98850K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TMBIM4 is not available on ENCORE database.





6 RBPs can affect the splicing of TMBIM4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETMBIM4ENSG00000155957.12chr12-6656306966563133665471196654722866563634665637490.124000.000000.00002includedK562AQR
SETMBIM4ENSG00000155957.12chr12-6656269466563133665471196654722866563634665637600.108000.000060.01902includedK562LARP4
SETMBIM4ENSG00000155957.12chr12-6656269466563133665471196654722866563634665637600.214000.002080.04087includedK562U2AF1
SETMBIM4ENSG00000155957.12chr12-6656306966563133665471196654722866563634665637490.059000.000130.09637includedK562ZRANB2
SETMBIM4ENSG00000155957.12chr12-6656269466563133665471196654722866563634665637600.089000.005400.07715includedK562U2AF2
A3SSTMBIM4ENSG00000228144.2chr12-665471196654722866547119665471906656363466563765-0.083000.000060.00855shorterK562AKAP8L
A3SSTMBIM4ENSG00000155957.12chr12-6651770866517849665177086651779866522675665228930.052000.000000.00000longerK562AQR
A3SSTMBIM4ENSG00000155957.12chr12-6653962066539754665396206653973866541687665417210.102000.000060.00051longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TMBIM4 is not avaliable on ENCORE database.