TM2D3

General Information

Gene Name       : TM2D3
Gene ID             : ENSG00000184277.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TM2D3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TM2D3ENSG00000184277.1215.7219.2417.48ENCSR000AEF
HepG2TM2D3ENSG00000184277.1223.3828.3825.88ENCSR985KAT
K562TM2D3ENSG00000184277.1219.3317.0418.18ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TM2D3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TM2D3 RNA is bound by 14 proteins.  







eCLIP assay for TM2D3 is not avaliable on ENCORE database.





14 proteins are bound to TM2D3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr15102182148102182279-3'-UTR,intron-Distal3.081984.88619HepG2LARP4
chr15102182540102182594-3'-UTR,intron-Distal4.9512712.39861HepG2FUBP3
chr15102186905102187001-3'-UTR,CDS,intron-Distal,intron-Proximal3.738807.47181HepG2PRPF8
chr15102182594102182652-3'-UTR,intron-Distal3.510055.15985HepG2FUBP3
chr15102182244102182292-3'-UTR,intron-Distal4.160703.88553HepG2ZC3H11A
chr15102186922102187006-3'-UTR,CDS,intron-Distal,intron-Proximal3.339654.49651HepG2SND1
chr15102182443102182504-3'-UTR,intron-Distal5.101055.79762HepG2FUBP3
chr15102182157102182230-3'-UTR,intron-Distal3.909384.59124HepG2FUBP3
chr15102182175102182291-3'-UTR,intron-Distal3.682515.99919HepG2DDX55
chr15102182352102182407-3'-UTR,intron-Distal3.205344.27074HepG2FUBP3
chr15102182659102182698-3'-UTR,CDS,intron-Distal5.816315.06516K562PUM2
chr15102186927102187103-3'-UTR,CDS,intron-Distal,intron-Proximal3.457746.36993K562SND1
chr15102182154102182210-3'-UTR,intron-Distal4.2462214.02202K562PUM2
chr15102182230102182294-3'-UTR,intron-Distal3.324424.03249HepG2FUBP3
chr15102182734102182848-3'-UTR,CDS,intron-Distal3.603466.46801HepG2SND1
chr15102190222102190284-5'-UTR,CDS,intron-Distal,intron-Proximal3.730803.02850K562YBX3
chr15102192280102192346-5'-UTR,intron-Distal,intron-Proximal4.349065.09344HepG2XPO5
chr15102192490102192570-5'-UTR,CDS,intron-Distal,intron-Proximal5.446184.57565HepG2DDX3X
chr15102192466102192565-CDS,intron-Distal,intron-Proximal5.655808.87727K562DDX3X
chr15102163891102163954-intron-Distal3.340596.07207HepG2PTBP1
chr15102163767102163812-intron-Distal3.659985.28137HepG2MATR3
chr15102162090102162207-intron-Distal4.024525.57156HepG2QKI
chr15102162565102162676-intron-Distal5.111676.80441HepG2MATR3
chr15102162298102162396-intron-Distal3.114353.72889HepG2SUGP2
chr15102162895102162997-intron-Distal4.6369910.11929HepG2MATR3
chr15102162797102162834-intron-Distal4.431733.62238HepG2MATR3
chr15102185026102185269-intron-Distal,intron-Proximal3.267203.20886K562PRPF8
chr15102162659102162713-intron-Distal4.153053.79098HepG2SUGP2
chr15102162329102162407-intron-Distal3.828504.87826HepG2MATR3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TM2D3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TM2D3 is not available on ENCORE database.

  • 58 RBPs can affect the levels of TM2D3.  








The Knockdown/knockout RNA-Seq assay for TM2D3 is not available on ENCORE database.





58 RBPs can affect the gene expression of TM2D3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TM2D3ENSG00000184277.8612.49460484.022300.339502.646701.89450HepG2AKAP8L
TM2D3ENSG00000184277.8905.03470668.448000.437104.910004.03800HepG2AUH
TM2D3ENSG00000184277.8602.16700481.650900.322102.617901.96680HepG2CKAP4
TM2D3ENSG00000184277.81269.73700971.527900.386102.621802.01130HepG2DDX3X
TM2D3ENSG00000184277.8235.55180445.71440-0.920106.229905.12570HepG2DDX55
TM2D3ENSG00000184277.8463.94410312.427900.570304.065902.89240HepG2DHX30
TM2D3ENSG00000184277.8457.23100323.929300.497103.779202.96630HepG2DNAJC21
TM2D3ENSG00000184277.8422.00350321.061900.394302.978602.30620HepG2DNAJC2
TM2D3ENSG00000184277.8420.39270863.24160-1.038009.242708.02410HepG2EIF4B
TM2D3ENSG00000184277.8888.39600603.088100.558704.887803.82350HepG2EIF4G2
TM2D3ENSG00000184277.81088.23270767.461800.503706.591305.72940HepG2ETF1
TM2D3ENSG00000184277.8505.58180894.54640-0.823208.611107.44900HepG2FXR1
TM2D3ENSG00000184277.8622.62830829.83570-0.414502.512001.87620HepG2G3BP1
TM2D3ENSG00000184277.8220.02050327.03250-0.571802.934002.27040HepG2HNRNPA1
TM2D3ENSG00000184277.8340.64150586.48030-0.783809.679008.12690HepG2HNRNPA2B1
TM2D3ENSG00000184277.8522.50590363.760900.522403.390902.63030HepG2HNRNPC
TM2D3ENSG00000184277.8790.85310489.078300.693209.721508.47930HepG2HNRNPF
TM2D3ENSG00000184277.8403.92700252.966000.675104.194603.43510HepG2HNRNPLL
TM2D3ENSG00000184277.8853.94780481.597300.8262011.114309.75640HepG2IGF2BP1
TM2D3ENSG00000184277.8400.05410791.58360-0.984504.199202.98960HepG2IGF2BP3
TM2D3ENSG00000184277.8413.50700714.38030-0.788805.479903.58220HepG2ILF3
TM2D3ENSG00000184277.8252.54020483.08100-0.935806.681105.37780HepG2LARP4
TM2D3ENSG00000184277.8594.11750894.85860-0.590904.783303.92790HepG2MAGOH
TM2D3ENSG00000184277.8561.15790899.87090-0.681305.512604.64610HepG2MATR3
TM2D3ENSG00000184277.8518.04420740.72460-0.515906.084205.23970HepG2PCBP1
TM2D3ENSG00000184277.8322.55380243.292600.406701.971401.31060HepG2PRPF4
TM2D3ENSG00000184277.8472.31630753.67580-0.674209.268008.38400HepG2PTBP1
TM2D3ENSG00000184277.8772.83960641.457300.268701.919701.46730HepG2RBM22
TM2D3ENSG00000184277.8533.77970838.80140-0.652109.036408.16070HepG2NELFE
TM2D3ENSG00000184277.8548.28730781.17040-0.510705.910405.05590HepG2RECQL
TM2D3ENSG00000184277.8920.80580526.934400.805209.266808.13450HepG2RPLP0
TM2D3ENSG00000184277.8188.92240261.70950-0.470202.109601.56570HepG2RPS19
TM2D3ENSG00000184277.8549.09200735.74500-0.422202.114501.41470HepG2RPS3A
TM2D3ENSG00000184277.8443.51960692.83470-0.643504.423502.77610HepG2SART3
TM2D3ENSG00000184277.8653.19320423.373100.625504.130903.29830HepG2SF3A3
TM2D3ENSG00000184277.8409.38570250.381100.709204.943804.02270HepG2SF3B1
TM2D3ENSG00000184277.8432.24620278.594800.633602.849502.05670HepG2SNRNP70
TM2D3ENSG00000184277.8883.37460480.521100.8783015.8008014.37700HepG2SRSF7
TM2D3ENSG00000184277.8384.65960539.38300-0.487702.746801.46770HepG2SSRP1
TM2D3ENSG00000184277.8439.39600678.29110-0.626408.346507.36410HepG2SUCLG1
TM2D3ENSG00000184277.8509.90780736.13630-0.529705.732004.97570HepG2TAF15
TM2D3ENSG00000184277.8267.27740354.26320-0.406502.487301.94640HepG2TRIM56
TM2D3ENSG00000184277.8122.26320213.67640-0.805403.885702.03980HepG2TROVE2
TM2D3ENSG00000184277.8525.83080368.029200.514703.347102.66200HepG2U2AF1
TM2D3ENSG00000184277.8536.35800362.499100.565105.359204.57110HepG2UTP3
TM2D3ENSG00000184277.8601.09140412.942200.541506.308405.57010HepG2ZNF622
TM2D3ENSG00000184277.8597.62960384.888600.634706.117905.32550K562AGGF1
TM2D3ENSG00000184277.8650.36180400.491900.699404.750203.88770K562AKAP8L
TM2D3ENSG00000184277.8980.93080682.673100.522904.479603.76620K562AQR
TM2D3ENSG00000184277.8322.78760452.07740-0.486003.263501.87180K562EXOSC5
TM2D3ENSG00000184277.8631.91520425.029300.572104.352803.28790K562KIF1C
TM2D3ENSG00000184277.8516.68500333.738400.630503.510402.49010K562NAA15
TM2D3ENSG00000184277.8397.57510575.03900-0.532403.386602.46560K562PCBP3
TM2D3ENSG00000184277.8308.29570441.05790-0.516703.514302.60450K562POLR2G
TM2D3ENSG00000184277.8832.62230397.192901.0677013.8287012.65980K562PUS1
TM2D3ENSG00000184277.8565.50080386.992400.547104.749803.99280K562RBM15
TM2D3ENSG00000184277.8581.20650376.195900.627505.509204.51760K562SRSF1
TM2D3ENSG00000184277.8363.28260502.01100-0.466603.643501.88720K562SRSF9
TM2D3ENSG00000184277.8315.27370442.41550-0.488803.349702.44710K562SYNCRIP
TM2D3ENSG00000184277.8363.50640505.48450-0.475703.837202.33180K562TROVE2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TM2D3 is not available on ENCORE database.





16 RBPs can affect the splicing of TM2D3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETM2D3ENSG00000184277.8chr15-102191898102191976102190206102190364102192473102192570-0.169000.000050.00173excludedK562SF3B4
SETM2D3ENSG00000184277.8chr15-1021918981021919761021902061021903641021924731021925870.165000.003710.05985includedHepG2U2AF1
SETM2D3ENSG00000184277.8chr15-102191898102191976102190206102190364102192473102192587-0.113000.000540.01929excludedK562AKAP8L
SETM2D3ENSG00000184277.8chr15-1021918981021919761021902061021903641021924731021925870.166000.004670.05028includedHepG2U2AF2
SETM2D3ENSG00000184277.8chr15-1021918981021919761021902061021903641021924731021925870.183000.001690.05915includedK562FXR1
SETM2D3ENSG00000184277.8chr15-1021918981021919761021902061021903641021924731021925870.141000.000460.04582includedHepG2SRSF7
SETM2D3ENSG00000184277.8chr15-102191898102191976102190206102190364102192473102192587-0.113000.003770.05005excludedK562PUS1
SETM2D3ENSG00000184277.8chr15-102191898102191976102190206102190364102192473102192587-0.230000.001120.04931excludedHepG2SFPQ
SETM2D3ENSG00000184277.8chr15-1021918981021919761021902061021903641021924731021925700.193000.000720.05204includedHepG2HNRNPL
SETM2D3ENSG00000184277.8chr15-1021918981021919761021902061021903641021924731021925870.291000.000100.03836includedK562PPIL4
SETM2D3ENSG00000184277.8chr15-1021918981021919761021902061021903641021924731021925700.214000.000190.05537includedHepG2NOL12
SETM2D3ENSG00000184277.8chr15-102191898102191976102190206102190364102192473102192587-0.136000.000060.00303excludedK562AGGF1
SETM2D3ENSG00000184277.8chr15-102190206102190364102186927102187102102192473102192579-0.102000.000550.09666excludedK562SAFB
SETM2D3ENSG00000184277.8chr15-1021918981021919761021902061021903641021924731021925700.192000.000210.03753includedHepG2KHSRP
A3SSTM2D3ENSG00000184277.8chr15-1021869271021871671021869271021871021021902061021903940.154000.000000.00000longerK562AQR
A5SSTM2D3ENSG00000184277.8chr15-102191898102192594102192473102192594102190206102190364-0.063000.001360.09964shorterK562AGGF1
A5SSTM2D3ENSG00000184277.8chr15-102191898102192594102192473102192594102190206102190364-0.153000.000030.00444shorterK562SF3B4
A5SSTM2D3ENSG00000184277.8chr15-1021918981021925941021924731021925941021902061021903640.140000.000110.02990longerK562DROSHA

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TM2D3 is not avaliable on ENCORE database.