TBC1D3

General Information

Gene Name       : TBC1D3
Gene ID             : ENSG00000274611.3
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: TBC1D3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TBC1D3ENSG00000274611.30.000.000.00ENCSR000AEF
HepG2TBC1D3ENSG00000274611.30.000.000.00ENCSR985KAT
K562TBC1D3ENSG00000274611.30.530.520.53ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TBC1D3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TBC1D3 RNA is bound by 12 proteins.  







eCLIP assay for TBC1D3 is not avaliable on ENCORE database.





12 proteins are bound to TBC1D3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr173635723436357284-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal5.0936028.76148HepG2U2AF2
chr173635808136358163-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.771096.93060K562EFTUD2
chr173635811636358152-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.1916523.66170HepG2PRPF8
chr173635723136357282-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.915728.27013K562U2AF2
chr173635812136358166-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.114135.41373HepG2PPIG
chr173635811236358166-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.8192019.57559HepG2U2AF2
chr173635808336358171-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.040157.03098HepG2EFTUD2
chr173635807936358167-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.569237.52282K562PRPF8
chr173635190136351997-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.0678712.35960HepG2BCLAF1
chr173635191636352008-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.167154.44630K562ZNF622
chr173635191536351997-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.409843.12941K562UCHL5
chr173635551736355546-intron-Distal3.282463.00589HepG2HNRNPC
chr173635003836350208-intron-Distal4.9569715.14933HepG2HNRNPK
chr173635807936358116-intron-Distal,intron-Proximal6.4631916.30191HepG2PRPF8
chr173635516436355233-intron-Distal3.147833.09653HepG2ILF3
chr173635153236351594-intron-Distal3.760603.19526HepG2CSTF2T
chr173635073236350819-intron-Distal3.444525.17145HepG2HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TBC1D3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TBC1D3 is not available on ENCORE database.

  • 38 RBPs can affect the levels of TBC1D3.  








The Knockdown/knockout RNA-Seq assay for TBC1D3 is not available on ENCORE database.





38 RBPs can affect the gene expression of TBC1D3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TBC1D3ENSG00000197681.811.4909083.78970-2.866306.306805.46510HepG2ACO1
TBC1D3ENSG00000197681.8120.2071068.747700.806003.129302.40570HepG2AUH
TBC1D3ENSG00000197681.859.616002.101204.8263012.5724010.55890HepG2CCAR1
TBC1D3ENSG00000197681.893.1949043.740401.091201.878001.30730HepG2DDX21
TBC1D3ENSG00000197681.8151.9715062.919101.272102.802302.20470HepG2EIF2S1
TBC1D3ENSG00000197681.819.7569062.20610-1.654703.557202.69170HepG2FIP1L1
TBC1D3ENSG00000197681.886.5199016.140102.4223013.1187011.71110HepG2HNRNPF
TBC1D3ENSG00000197681.844.2601015.895201.477304.024903.16650HepG2IGF2BP1
TBC1D3ENSG00000197681.872.854302.232405.0282012.0097010.28770HepG2LARP4
TBC1D3ENSG00000197681.821.1235056.32990-1.415103.381302.12770HepG2LARP7
TBC1D3ENSG00000197681.810.9028054.04540-2.309506.223903.82820HepG2PHF6
TBC1D3ENSG00000197681.873.8591030.273501.286602.057901.38220HepG2PRPF4
TBC1D3ENSG00000197681.88.5679070.21740-3.034803.971503.17490HepG2RBM25
TBC1D3ENSG00000197681.824.3829074.50820-1.611504.439003.84780HepG2SRFBP1
TBC1D3ENSG00000197681.8111.7178064.113300.801102.410001.62800HepG2TIA1
TBC1D3ENSG00000197681.874.2858026.429001.490903.002502.42030HepG2TRIM56
TBC1D3ENSG00000197681.820.4374053.20180-1.380302.838302.20200HepG2U2AF1
TBC1D3ENSG00000197681.811.923000.0000099999.999902.401801.49100HepG2U2AF2
TBC1D3ENSG00000197681.823.059903.297902.805703.327401.97090K562ABCF1
TBC1D3ENSG00000197681.835.538605.141702.789003.528802.43810K562BCLAF1
TBC1D3ENSG00000197681.882.668004.495604.2006012.3660010.48010K562BOP1
TBC1D3ENSG00000197681.834.280202.664503.685307.166305.27230K562CCAR1
TBC1D3ENSG00000197681.842.909404.775803.167402.914002.11030K562CPSF6
TBC1D3ENSG00000197681.856.5345016.011401.819904.925702.93960K562DDX19B
TBC1D3ENSG00000197681.832.303809.559501.756602.887502.22210K562DDX47
TBC1D3ENSG00000197681.824.463702.375003.364604.876303.72780K562FIP1L1
TBC1D3ENSG00000197681.853.191104.867703.449802.340301.55210K562FMR1
TBC1D3ENSG00000197681.839.067004.556303.099905.194604.11300K562GPKOW
TBC1D3ENSG00000197681.819.670701.955803.330102.911901.95360K562HNRNPM
TBC1D3ENSG00000197681.829.339303.216603.189104.801703.76150K562HSPD1
TBC1D3ENSG00000197681.835.180304.448902.983205.274604.04120K562METAP2
TBC1D3ENSG00000197681.829.345506.383802.200602.532801.81510K562NSUN2
TBC1D3ENSG00000197681.826.093302.699503.272803.489102.54990K562PPIG
TBC1D3ENSG00000197681.818.209302.240003.023003.033801.99230K562RCC2
TBC1D3ENSG00000197681.857.124704.345803.716309.472507.59510K562SF3B1
TBC1D3ENSG00000197681.815.060200.0000099999.999905.089003.90960K562SF3B4
TBC1D3ENSG00000197681.831.533206.437202.292303.500802.46350K562SRPK2
TBC1D3ENSG00000197681.834.019503.159903.428306.091504.53980K562SUPV3L1
TBC1D3ENSG00000197681.828.344307.433901.930802.356201.70100K562TARDBP
TBC1D3ENSG00000197681.833.681903.337203.335205.925904.37710K562UCHL5
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TBC1D3 is not available on ENCORE database.





3 RBPs can affect the splicing of TBC1D3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETBC1D3ENSG00000197681.8chr17-3634700936347082363467613634684736351935363519960.277000.002860.05789includedHepG2SRSF1
SETBC1D3ENSG00000197681.8chr17-363470093634708236346761363468473635193536351996-0.329000.002770.08392excludedHepG2HNRNPC
A3SSTBC1D3ENSG00000197681.8chr17-3635360036353787363536003635376536357157363572720.088000.002450.01541longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TBC1D3 is not avaliable on ENCORE database.