SFMBT2

General Information

Gene Name       : SFMBT2
Gene ID             : ENSG00000198879.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SFMBT2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SFMBT2ENSG00000198879.1113.5613.9313.75ENCSR000AEF
HepG2SFMBT2ENSG00000198879.110.020.030.03ENCSR985KAT
K562SFMBT2ENSG00000198879.115.616.185.89ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SFMBT2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SFMBT2 RNA is bound by 33 proteins.  







eCLIP assay for SFMBT2 is not avaliable on ENCORE database.





33 proteins are bound to SFMBT2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1073262997326398-3'-UTR,intron-Distal3.719225.32884K562KHSRP
chr1073261727326284-3'-UTR,intron-Distal,intron-Proximal4.8485411.91013K562GTF2F1
chr1072052117205298-3'-UTR,intron-Distal3.391593.77784K562RBM15
chr1072055057205563-3'-UTR,intron-Distal4.551155.65349K562RBM15
chr1072053927205500-3'-UTR,intron-Distal4.791445.85529K562RBM15
chr1073271417327219-3'-UTR,intron-Distal3.213834.08064K562KHSRP
chr1073261947326272-3'-UTR,intron-Distal,intron-Proximal3.882156.67564K562CSTF2T
chr1073262147326270-3'-UTR,intron-Distal3.326393.74485K562DROSHA
chr1072056607205737-3'-UTR,CDS,intron-Distal4.119903.73926K562RBM15
chr1073262047326284-3'-UTR,intron-Distal,intron-Proximal3.345624.72639K562KHSRP
chr1074238337423907-5'-UTR,CDS,intron-Distal4.506357.95258K562DDX24
chr1074512457451305-5'-UTR,intron-Distal,intron-Proximal4.181154.33692K562NONO
chr1074506947450780-5'-UTR,intron-Distal,intron-Proximal3.685574.50953K562CSTF2T
chr1073278197327912-CDS,intron-Distal,intron-Proximal3.149844.39009K562IGF2BP2
chr1074096087409784-CDS,intron-Distal,intron-Proximal4.337905.21007K562SRSF1
chr1074122447412330-CDS,intron-Distal4.2334512.54198K562DDX24
chr1072477317247802-CDS,intron-Distal,intron-Proximal3.603315.75231K562AQR
chr1072478607247905-CDS,intron-Distal,intron-Proximal3.894793.31221K562U2AF1
chr1074237607423833-CDS,intron-Distal,intron-Proximal3.531734.70460K562DDX24
chr1074097877409852-CDS,intron-Distal,intron-Proximal4.089067.51551K562UCHL5
chr1072698457269900-CDS,intron-Distal,intron-Proximal3.718564.79276K562ZNF622
chr1074122407412331-CDS,intron-Distal,intron-Proximal3.4134210.55732K562ZNF622
chr1073188677318951-CDS,intron-Distal4.096654.30417K562YBX3
chr1072478557247906-CDS,intron-Distal,intron-Proximal4.409254.06574K562U2AF2
chr1072624887262550-CDS,intron-Distal,intron-Proximal5.472875.40008K562SF3B4
chr1074122397412338-CDS,intron-Distal,intron-Proximal4.6860417.61288K562UCHL5
chr1073187947318942-CDS,intron-Distal,intron-Proximal3.182233.40058K562PRPF8
chr1073965707396667-intron-Distal4.777476.13283K562NONO
chr1074179827418075-intron-Distal3.597823.84589K562HNRNPL
chr1073617377361859-intron-Distal3.9898215.33815K562PTBP1
chr1073615767361641-intron-Distal5.8465321.37948K562PTBP1
chr1073257557325817-intron-Distal,intron-Proximal4.065884.07352K562KHSRP
chr1074197487419900-intron-Distal4.5718612.40060K562YBX3
chr1074176647417726-intron-Distal3.880353.39667K562HNRNPL
chr1073774547377566-intron-Distal4.326844.66266K562TARDBP
chr1074208477420945-intron-Distal5.1505231.57597K562HNRNPL
chr1073397667339835-intron-Distal4.131914.27660K562HNRNPL
chr1074187767418820-intron-Distal3.575633.02850K562YBX3
chr1074199247419997-intron-Distal4.548755.18391K562HNRNPL
chr1074208437420920-intron-Distal7.6140167.97723K562AGGF1
chr1074186537418663-intron-Distal5.1336114.58753K562AGGF1
chr1074498857449949-intron-Distal3.056434.55729K562TIA1
chr1074210087421050-intron-Distal4.136304.24993K562HNRNPL
chr1073660127366138-intron-Distal3.943413.80299K562HNRNPL
chr1074495987449627-intron-Distal3.965533.02711K562EWSR1
chr1073406687340714-intron-Distal4.276613.37631K562HNRNPL
chr1074197797419818-intron-Distal4.256279.59054K562HNRNPL
chr1074215757421617-intron-Distal5.6597620.96201K562AGGF1
chr1074502717450346-intron-Distal3.481024.71867K562TIA1
chr1074080407408167-intron-Distal3.520713.98203K562MATR3
chr1074176777417727-intron-Distal6.4220612.00098K562AGGF1
chr1074528607452947-intron-Distal3.414166.13299K562GTF2F1
chr1072144117214456-intron-Distal,intron-Proximal4.747594.13847K562AQR
chr1074178347417881-intron-Distal4.867418.77893K562AGGF1
chr1073405557340673-intron-Distal3.632064.13833K562GTF2F1
chr1074515247451604-intron-Distal4.120834.94081K562FUS
chr1072798957279981-intron-Distal3.954103.34601K562HNRNPK
chr1073405527340758-intron-Distal4.8201753.56562K562AGGF1
chr1074508967450976-intron-Distal4.396473.84029K562DROSHA
chr1074217667421813-intron-Distal4.343815.63065K562HNRNPL
chr1072775587277608-intron-Distal4.772285.76685K562EXOSC5
chr1074208537420923-intron-Distal4.885877.57924K562YBX3
chr1072066507206727-intron-Distal3.794273.08314K562TARDBP
chr1074198257419924-intron-Distal6.5175529.73254K562HNRNPL
chr1074215707421615-intron-Distal4.990789.22379K562HNRNPL
chr1074187787418821-intron-Distal5.0326626.71155K562AGGF1
chr1074197357419779-intron-Distal4.843817.69482K562HNRNPL
chr1073973157397410-intron-Distal4.023983.69425K562TARDBP
chr1073922147392319-intron-Distal3.086713.94756K562SAFB
chr1074200597420117-intron-Distal8.4022564.02330K562AGGF1
chr1074204997420635-intron-Distal7.9710099.94305K562AGGF1
chr1074181427418280-intron-Distal5.3825711.17843K562HNRNPL
chr1073588067358868-intron-Distal4.924807.44287K562TARDBP
chr1072618537262011-intron-Distal3.745613.02234K562KHSRP
chr1074500277450089-intron-Distal4.059383.70058K562CSTF2T
chr1073585117358618-intron-Distal4.200183.87294K562TARDBP
chr1074063217406400-intron-Distal3.915973.37631K562HNRNPL
chr1073965017396558-intron-Distal4.099733.06347K562NONO
chr1073923967392480-intron-Distal3.045024.73846K562SAFB2
chr1074207507420841-intron-Distal7.2056559.07158K562AGGF1
chr1074229737423039-intron-Distal4.780168.77893K562AGGF1
chr1074197937419815-intron-Distal7.6355338.59595K562AGGF1
chr1074186277418653-intron-Distal4.4293816.29028K562AGGF1
chr1073618597362000-intron-Distal5.4461822.63563K562PTBP1
chr1072674097267490-intron-Distal3.390654.30679K562KHSRP
chr1073616417361711-intron-Distal6.3608133.03886K562PTBP1
chr1072782397278299-intron-Distal3.807475.20960K562EXOSC5
chr1072775077277610-intron-Distal3.237183.44195K562TARDBP
chr1074515187451603-intron-Distal3.312706.01711K562CSTF2T
chr1074180087418058-intron-Distal6.6539114.76922K562AGGF1
chr1074183427418396-intron-Distal3.748833.39667K562HNRNPL
chr1074199227420100-intron-Distal4.596859.83739K562AKAP8L
chr1074525907452642-intron-Distal4.755546.36475K562CSTF2T
chr1073279537328064-intron-Distal,intron-Proximal4.152834.76003K562KHSRP
chr1072650017265076-intron-Distal3.726133.33309K562SAFB
chr1074518487451928-intron-Distal3.293824.01547K562TIA1
chr1074528247452881-intron-Distal5.486247.12981K562DDX24
chr1074528547452966-intron-Distal3.179048.00599K562NCBP2
chr1073253357325449-intron-Distal3.303967.63703K562AGGF1
chr1073568237356913-intron-Distal6.9730227.61809K562PTBP1
chr1073588057358850-intron-Distal4.337503.26170K562EIF4G2
chr1074528817452940-intron-Distal4.622016.25151K562DDX24
chr1074208427420943-intron-Distal4.456785.61307K562GTF2F1
chr1073173927317480-intron-Distal3.944635.44125K562PTBP1
chr1074217517421814-intron-Distal3.913103.43253K562YBX3
chr1072774147277491-intron-Distal4.505215.79092K562TARDBP
chr1074515427451605-intron-Distal3.200273.08539K562EWSR1
chr1074528317452981-intron-Distal4.480798.23108K562UCHL5
chr1072492797249353-intron-Distal6.4659213.17986K562PTBP1
chr1074209237421003-intron-Distal4.533664.72754K562YBX3
chr1074198157419917-intron-Distal9.92859221.12705K562AGGF1
chr1073964187396487-intron-Distal3.120643.38183K562NONO
chr1073404937340648-intron-Distal6.7058327.10803K562HNRNPL
chr1074197907419922-intron-Distal3.986393.77708K562GTF2F1
chr1073404777340552-intron-Distal7.4559437.65656K562AGGF1
chr1074187777418821-intron-Distal3.525105.26345K562HNRNPL
chr1074001017400237-intron-Distal4.256214.92679K562HNRNPA1
chr1074214747421545-intron-Distal3.669855.05215K562HNRNPL
chr1072771267277166-intron-Distal4.346054.48623K562EXOSC5
chr1072138127213857-intron-Distal,intron-Proximal5.153075.69951K562AQR
chr1072774147277558-intron-Distal6.3479321.00970K562EXOSC5
chr1074209457420991-intron-Distal4.099797.51820K562HNRNPL
chr1073785737378631-intron-Distal3.904486.94220K562TARDBP
chr1074212837421321-intron-Distal4.313205.53787K562HNRNPL
chr1074522387452292-intron-Distal4.176614.48935K562CSTF2T
chr1074495767449627-intron-Distal3.947883.19904K562TIA1
chr1074498987449950-intron-Distal3.244003.41462K562EWSR1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SFMBT2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SFMBT2 is not available on ENCORE database.

  • 30 RBPs can affect the levels of SFMBT2.  








The Knockdown/knockout RNA-Seq assay for SFMBT2 is not available on ENCORE database.





30 RBPs can affect the gene expression of SFMBT2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SFMBT2ENSG00000198879.719.248101.834303.391302.889702.34700HepG2AKAP1
SFMBT2ENSG00000198879.714.518102.514202.529602.090601.50260HepG2PUM2
SFMBT2ENSG00000198879.725.651900.500005.681005.353804.49570HepG2U2AF1
SFMBT2ENSG00000198879.71331.586101642.52240-0.302803.288102.28520K562ATP5C1
SFMBT2ENSG00000198879.7913.88760710.376700.363302.639501.83820K562EIF4A3
SFMBT2ENSG00000198879.7836.88890639.722000.387503.630902.27670K562EIF4B
SFMBT2ENSG00000198879.7596.71560738.75990-0.308102.352701.78630K562FXR1
SFMBT2ENSG00000198879.7959.34810748.865100.357202.911301.80920K562HNRNPA1
SFMBT2ENSG00000198879.71066.68140829.294800.363103.564202.54930K562HNRNPU
SFMBT2ENSG00000198879.71050.08730842.132800.318302.385801.60260K562MAGOH
SFMBT2ENSG00000198879.7944.28160744.750100.342403.406302.51350K562MTPAP
SFMBT2ENSG00000198879.71037.15800709.369300.547905.731503.97430K562NCBP2
SFMBT2ENSG00000198879.71285.358501553.19160-0.273102.294501.41880K562PUM2
SFMBT2ENSG00000198879.71289.270701512.71680-0.230601.973101.45730K562RBM15
SFMBT2ENSG00000198879.71240.96490958.146400.373003.197901.46300K562RBM17
SFMBT2ENSG00000198879.7865.47080665.078100.379902.996201.60440K562RBM25
SFMBT2ENSG00000198879.7684.09970501.291700.448503.640502.50440K562RCC2
SFMBT2ENSG00000198879.7413.32390623.61160-0.593403.804202.84270K562RPS19
SFMBT2ENSG00000198879.7626.21770842.39550-0.427802.676801.69110K562RPS3
SFMBT2ENSG00000198879.71016.13230816.507600.315402.775301.95930K562SF3A3
SFMBT2ENSG00000198879.7743.84390494.378000.589304.189602.97290K562SF3B1
SFMBT2ENSG00000198879.71279.44180729.057700.8113014.7422012.64280K562SF3B4
SFMBT2ENSG00000198879.71291.22050817.872100.658702.608801.43030K562SNRNP200
SFMBT2ENSG00000198879.71139.22960836.527500.445506.509905.14530K562SRPK2
SFMBT2ENSG00000198879.7590.27700802.09900-0.442403.630402.82670K562SRSF1
SFMBT2ENSG00000198879.7980.69990783.045400.324602.474001.70580K562TIA1
SFMBT2ENSG00000198879.7977.22190768.416300.346702.348601.35960K562TRA2A
SFMBT2ENSG00000198879.71087.89350679.691900.678503.515402.24960K562U2AF1
SFMBT2ENSG00000198879.71183.19780701.852200.7534012.3304010.61620K562U2AF2
SFMBT2ENSG00000198879.7942.53760750.778400.328102.456901.63010K562WDR3
SFMBT2ENSG00000198879.71003.33920780.708000.361904.291803.25410K562WDR43
SFMBT2ENSG00000198879.71476.569201160.371000.347602.932502.04110K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SFMBT2 is not available on ENCORE database.





5 RBPs can affect the splicing of SFMBT2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESFMBT2ENSG00000198879.7chr10-723950972396497230585723069572423757242446-0.282000.000800.02615excludedK562AKAP8L
SESFMBT2ENSG00000198879.7chr10-7267225726733772623727262499726981672698990.172000.005450.06650includedK562PUS1
SESFMBT2ENSG00000198879.7chr10-723950972396497230585723069572423757242446-0.324000.001070.01796excludedK562PUS1
SESFMBT2ENSG00000198879.7chr10-7267225726733772623727262499726981672698990.417000.000240.00598includedK562U2AF2
SESFMBT2ENSG00000198879.7chr10-723950972396497230585723069572423757242446-0.306000.000040.00198excludedK562AGGF1
A3SSSFMBT2ENSG00000198879.7chr10-7214456721465572144567214623721795172181270.296000.009670.05142longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SFMBT2 is not avaliable on ENCORE database.