RNASEH2B

General Information

Gene Name       : RNASEH2B
Gene ID             : ENSG00000136104.20
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: RNASEH2B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RNASEH2BENSG00000136104.20103.36101.01102.19ENCSR000AEF
HepG2RNASEH2BENSG00000136104.2020.6246.4733.55ENCSR985KAT
K562RNASEH2BENSG00000136104.2049.2956.2952.79ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RNASEH2B is not avaliable on ENCORE database.



Proteins bound to RNA
  • RNASEH2B RNA is bound by 10 proteins.  







eCLIP assay for RNASEH2B is not avaliable on ENCORE database.





10 proteins are bound to RNASEH2B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr135148392751484031+5'-UTR4.022595.06399K562DDX3X
chr135152804151528088+CDS,intron-Distal3.166683.50696K562BUD13
chr135150904051509112+CDS5.039198.53120K562LIN28B
chr135150893351509026+CDS,intron-Proximal3.242493.68839K562KHSRP
chr135148421251484274+CDS3.732976.98150K562DDX3X
chr135151742351517518+CDS,intron-Proximal4.123468.55183K562SF3B4
chr135150366851503719+CDS,intron-Proximal3.991224.07825K562YBX3
chr135153049451530544+CDS,intron-Distal4.198863.38968HepG2BCLAF1
chr135148935951489435+intron-Distal3.633075.07626HepG2PTBP1
chr135153580051535871+intron-Distal3.804793.29248HepG2SUGP2
chr135152558851525666+intron-Distal3.146473.35050HepG2SUGP2
chr135153950251539617+intron-Distal4.727455.84190HepG2HNRNPL
chr135154030251540436+intron-Distal3.303353.40400K562HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RNASEH2B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RNASEH2B is not available on ENCORE database.

  • 56 RBPs can affect the levels of RNASEH2B.  








The Knockdown/knockout RNA-Seq assay for RNASEH2B is not available on ENCORE database.





56 RBPs can affect the gene expression of RNASEH2B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RNASEH2BENSG00000136104.14265.99570365.45590-0.458302.851202.15650HepG2AUH
RNASEH2BENSG00000136104.14210.62060338.53900-0.684703.393502.30290HepG2CCAR1
RNASEH2BENSG00000136104.14140.94520221.81580-0.654202.741601.97230HepG2CIRBP
RNASEH2BENSG00000136104.14143.50520241.10120-0.748505.038804.19050HepG2CKAP4
RNASEH2BENSG00000136104.14142.52130213.47700-0.582902.295401.66160HepG2CPSF6
RNASEH2BENSG00000136104.14233.00900347.41880-0.576304.435703.53210HepG2DAZAP1
RNASEH2BENSG00000136104.14137.83630229.44270-0.735203.771602.59940HepG2DDX5
RNASEH2BENSG00000136104.14121.79580223.21530-0.874004.266103.53890HepG2EIF2S1
RNASEH2BENSG00000136104.14115.52220246.68460-1.094506.500005.51960HepG2EIF4A3
RNASEH2BENSG00000136104.14165.81410241.99940-0.545402.075601.51710HepG2GPKOW
RNASEH2BENSG00000136104.14119.57740179.81820-0.588602.079301.50980HepG2HNRNPA1
RNASEH2BENSG00000136104.14127.33530200.00290-0.651402.596201.92240HepG2HNRNPC
RNASEH2BENSG00000136104.14175.82280248.67680-0.500102.647301.94500HepG2HNRNPF
RNASEH2BENSG00000136104.14117.49480233.76610-0.992505.466004.50970HepG2HNRNPK
RNASEH2BENSG00000136104.14218.84090316.47290-0.532203.584302.82370HepG2HNRNPL
RNASEH2BENSG00000136104.1470.58850230.94390-1.7100012.2721011.06830HepG2HNRNPLL
RNASEH2BENSG00000136104.14138.48640244.87440-0.822305.201504.24140HepG2IGF2BP1
RNASEH2BENSG00000136104.14144.40540234.68700-0.700603.193502.47410HepG2IGF2BP2
RNASEH2BENSG00000136104.14248.87130357.56580-0.522802.401401.63140HepG2LARP4
RNASEH2BENSG00000136104.14355.61380250.360800.506202.247501.67530HepG2MATR3
RNASEH2BENSG00000136104.14149.97240235.51840-0.651102.162901.31520HepG2MTPAP
RNASEH2BENSG00000136104.14105.87090228.22660-1.108206.625905.51650HepG2PABPC4
RNASEH2BENSG00000136104.14136.15040219.10310-0.686402.746001.70950HepG2PCBP2
RNASEH2BENSG00000136104.14267.72870348.83780-0.381801.884801.32550HepG2PUM2
RNASEH2BENSG00000136104.14167.13660246.43220-0.560202.296301.71780HepG2QKI
RNASEH2BENSG00000136104.14149.37490267.90380-0.842805.149204.25600HepG2RPLP0
RNASEH2BENSG00000136104.14116.40020207.74130-0.835703.455202.39930HepG2RPS10
RNASEH2BENSG00000136104.1488.27070145.45000-0.720502.733902.12190HepG2RPS19
RNASEH2BENSG00000136104.14148.87650228.59260-0.618702.702302.00430HepG2SF3B1
RNASEH2BENSG00000136104.14209.72400315.31770-0.588304.054003.22800HepG2SLBP
RNASEH2BENSG00000136104.14329.81060247.245100.415602.023501.60140HepG2SRSF1
RNASEH2BENSG00000136104.14141.99790244.32090-0.782905.293904.38190HepG2SRSF7
RNASEH2BENSG00000136104.14128.73070201.13040-0.643802.744102.19430HepG2SRSF9
RNASEH2BENSG00000136104.14230.21790343.91320-0.579004.129703.53010HepG2SSB
RNASEH2BENSG00000136104.14295.02910369.26800-0.323801.835401.30980HepG2SUCLG1
RNASEH2BENSG00000136104.14117.15810225.08140-0.942005.063004.12560HepG2TARDBP
RNASEH2BENSG00000136104.14119.58700193.09980-0.691303.346702.80590HepG2TIAL1
RNASEH2BENSG00000136104.14134.96080194.77910-0.529302.506601.96430HepG2TRIM56
RNASEH2BENSG00000136104.14205.35900340.06320-0.727703.566102.61010HepG2UBE2L3
RNASEH2BENSG00000136104.14157.09330225.81390-0.523502.756502.21020HepG2ZNF622
RNASEH2BENSG00000136104.14472.21040856.80200-0.859508.923507.96660K562AQR
RNASEH2BENSG00000136104.14357.84550467.45430-0.385502.587301.66280K562BCLAF1
RNASEH2BENSG00000136104.14982.37720733.195600.422005.003104.16290K562DDX47
RNASEH2BENSG00000136104.14280.80590423.10940-0.591503.525802.48840K562EFTUD2
RNASEH2BENSG00000136104.14574.15800432.694200.408003.021102.18990K562EIF3G
RNASEH2BENSG00000136104.14615.73800405.663800.601903.696302.85290K562G3BP2
RNASEH2BENSG00000136104.14285.66020420.20660-0.556803.455102.79830K562HNRNPC
RNASEH2BENSG00000136104.14407.21970560.49250-0.460902.718201.49920K562HNRNPK
RNASEH2BENSG00000136104.141152.65430740.983500.637306.648805.42660K562HSPD1
RNASEH2BENSG00000136104.14394.19110561.17440-0.509602.836001.79550K562IGF2BP2
RNASEH2BENSG00000136104.14438.24830570.79540-0.381202.450901.34880K562IGF2BP3
RNASEH2BENSG00000136104.14162.97710335.81190-1.043006.371204.89020K562KRR1
RNASEH2BENSG00000136104.14235.74580376.74070-0.676304.121902.98740K562PSIP1
RNASEH2BENSG00000136104.14439.81650573.01180-0.381702.642701.99110K562PTBP1
RNASEH2BENSG00000136104.14238.18790343.63780-0.528802.881501.87000K562RCC2
RNASEH2BENSG00000136104.14229.19700325.76870-0.507302.416101.47420K562SRFBP1
RNASEH2BENSG00000136104.14423.67860561.74120-0.406902.665301.96980K562SRSF1
RNASEH2BENSG00000136104.14389.26410530.51880-0.446702.933401.84770K562SRSF5
RNASEH2BENSG00000136104.14426.30260568.52170-0.415302.529501.85110K562TARDBP
RNASEH2BENSG00000136104.14242.41150362.37240-0.580003.041002.05560K562TIAL1
RNASEH2BENSG00000136104.14387.46650538.13900-0.473903.077901.91480K562TRA2A
RNASEH2BENSG00000136104.14203.76880384.87420-0.917507.271405.57790K562TRIM56
RNASEH2BENSG00000136104.141005.812201290.48230-0.359503.153701.64870K562UBE2L3
RNASEH2BENSG00000136104.14467.86490632.81610-0.435702.907302.17090K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RNASEH2B is not available on ENCORE database.





2 RBPs can affect the splicing of RNASEH2B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERNASEH2BENSG00000136104.14chr13+5148713051487267514838135148427651501542515016140.057000.000360.07261includedK562WDR3
SERNASEH2BENSG00000136104.14chr13+5151598551516190515090205150913551517456515175300.078000.002960.06391includedHepG2HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RNASEH2B is not avaliable on ENCORE database.