PRSS21

General Information

Gene Name       : PRSS21
Gene ID             : ENSG00000007038.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PRSS21)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PRSS21ENSG00000007038.1017.1823.6020.39ENCSR000AEF
HepG2PRSS21ENSG00000007038.100.000.000.00ENCSR985KAT
K562PRSS21ENSG00000007038.1075.2451.2063.22ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PRSS21 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PRSS21 RNA is bound by 34 proteins.  







eCLIP assay for PRSS21 is not avaliable on ENCORE database.





34 proteins are bound to PRSS21 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1628716592871710+3'-UTR,intron-Distal4.386979.84602K562PABPC4
chr1628710352871113+3'-UTR,CDS,intron-Distal,intron-Proximal3.671945.62184K562GRWD1
chr1628712462871381+3'-UTR,CDS,intron-Distal,intron-Proximal3.233977.94539K562FUS
chr1628715662871626+3'-UTR,CDS,intron-Distal3.819454.14399K562LSM11
chr1628715832871631+3'-UTR,CDS,intron-Distal4.307513.35417K562METAP2
chr1628712582871373+3'-UTR,CDS,intron-Distal,intron-Proximal4.6020613.15302K562HNRNPK
chr1628713232871373+3'-UTR,CDS,intron-Distal,intron-Proximal4.4136216.55325K562SF3B4
chr1628715772871664+3'-UTR,CDS,intron-Distal3.515744.14719K562IGF2BP2
chr1628709872871057+3'-UTR,CDS,intron-Distal3.463739.30098K562YBX3
chr1628715652871659+3'-UTR,CDS,intron-Distal3.2757712.53117K562PABPC4
chr1628711312871226+3'-UTR,intron-Distal,intron-Proximal3.381906.07287K562HNRNPK
chr1628714272871512+3'-UTR,CDS,intron-Distal4.121375.48330K562UPF1
chr1628714062871457+3'-UTR,CDS,intron-Distal3.566513.85419K562NOLC1
chr1628708852870965+3'-UTR,CDS,intron-Distal,intron-Proximal4.3818833.26582K562SF3B4
chr1628711732871222+3'-UTR,intron-Distal,intron-Proximal3.387516.44106K562DROSHA
chr1628715762871622+3'-UTR,CDS,intron-Distal3.454833.93112K562RBM15
chr1628679662867978+5'-UTR,CDS,intron-Proximal6.7135822.68660K562AQR
chr1628673652867433+CDS,intron-Proximal4.4664413.02048K562DROSHA
chr1628673752867441+CDS,intron-Proximal3.426084.50192K562FAM120A
chr1628677102867809+CDS,intron-Proximal4.0714530.13472K562RBFOX2
chr1628678272867936+CDS3.004163.86816K562FTO
chr1628673682867491+CDS,intron-Proximal3.5497024.45524K562GEMIN5
chr1628673692867449+CDS,intron-Proximal4.3388518.67867K562RBFOX2
chr1628677022867815+CDS,intron-Proximal3.174039.04761K562CSTF2T
chr1628674382867472+CDS,intron-Proximal4.7251017.18244K562AQR
chr1628678242867877+CDS3.860959.16086K562UCHL5
chr1628677072867815+CDS,intron-Proximal4.6344331.56681K562BUD13
chr1628672832867333+CDS3.795735.06399K562DDX3X
chr1628677252867833+CDS,intron-Proximal3.1894224.13367K562PRPF8
chr1628678962867958+CDS3.109166.58309K562SRSF1
chr1628673592867450+CDS,intron-Proximal4.6648521.17188K562DDX24
chr1628673542867438+CDS,intron-Proximal3.2016313.08624K562AQR
chr1628673582867454+CDS,intron-Proximal4.9314624.10024K562BUD13
chr1628677752867826+CDS,intron-Proximal5.5948037.23048K562AQR
chr1628673692867438+CDS,intron-Proximal4.4247614.20741K562CSTF2T
chr1628673772867476+CDS,intron-Proximal3.0664815.28538K562PRPF8
chr1628673552867447+CDS,intron-Proximal5.5024631.29396K562GTF2F1
chr1628674042867439+CDS,intron-Proximal3.492746.02234K562UCHL5
chr1628677392867808+CDS,intron-Proximal4.5419723.51718K562SF3B4
chr1628707942870863+intron-Distal,intron-Proximal4.656855.85529K562RBM15
chr1628676982867802+intron-Distal,intron-Proximal3.5878414.42791K562DDX24
chr1628695832869654+intron-Distal3.023863.44056K562AKAP1
chr1628703162870393+intron-Distal5.0339623.97783K562BUD13
chr1628712502871298+intron-Distal,intron-Proximal3.321005.77413K562DDX24
chr1628698912869945+intron-Distal4.034645.89564K562AKAP8L
chr1628691962869250+intron-Distal4.574154.36078K562GTF2F1
chr1628703252870370+intron-Distal5.245235.93845K562DDX24
chr1628691852869230+intron-Distal3.774517.18598K562DROSHA
chr1628702912870308+intron-Distal4.169353.42734K562PTBP1
chr1628695532869674+intron-Distal3.796357.67917K562HNRNPK
chr1628702802870332+intron-Distal3.519036.44106K562DROSHA
chr1628692052869253+intron-Distal3.157824.49816K562UCHL5
chr1628708062870953+intron-Distal,intron-Proximal3.402277.98598K562SMNDC1
chr1628703412870362+intron-Distal3.041755.12902K562SF3B4
chr1628676182867685+intron-Distal4.1404213.76690K562PRPF8
chr1628676082867674+intron-Distal3.7921811.71348K562RBFOX2
chr1628708282870885+intron-Distal,intron-Proximal5.3054414.45274K562SF3B4
chr1628713022871343+intron-Distal,intron-Proximal3.375114.99373K562PCBP1
chr1628707292870764+intron-Distal4.447644.88343K562NOLC1
chr1628702532870315+intron-Distal3.3497711.36875K562BUD13
chr1628708172870879+intron-Distal,intron-Proximal3.040399.18328K562BUD13
chr1628690742869114+intron-Distal3.016826.13867K562BUD13
chr1628675372867575+intron-Distal,intron-Proximal4.711929.56266K562AQR
chr1628693452869492+intron-Distal5.6581911.20102K562HNRNPK
chr1628692732869315+intron-Distal4.138713.34601K562HNRNPK
chr1628702752870332+intron-Distal4.9519626.46700K562SF3B4
chr1628691572869248+intron-Distal3.952517.99428K562DDX24
chr1628675392867580+intron-Distal,intron-Proximal3.510815.75957K562RBFOX2
chr1628698822869938+intron-Distal3.234003.73797K562CSTF2T
chr1628676112867670+intron-Distal3.152385.98540K562GTF2F1
chr1628691892869245+intron-Distal4.524603.42734K562PTBP1
chr1628707772870842+intron-Distal3.938456.16252K562PHF6
chr1628676272867654+intron-Distal4.199878.26531K562BUD13
chr1628675392867579+intron-Distal,intron-Proximal3.700307.14018K562BUD13
chr1628696322869720+intron-Distal3.766525.79087K562FUS
chr1628674722867499+intron-Proximal4.7863712.86643K562AQR
chr1628679982868036+intron-Proximal4.219006.34856K562DROSHA
chr1628679782868014+intron-Proximal5.9174135.16110K562AQR
chr1628673702867418+intron-Proximal4.158127.87531K562FASTKD2
chr1628677242867800+intron-Proximal3.241546.56632K562DROSHA
chr1628677282867798+intron-Proximal3.2863015.21835K562GTF2F1
chr1628689882869023+intron-Proximal3.278326.32494K562UCHL5
chr1628673692867421+intron-Proximal4.223444.25524K562CPSF6
chr1628690062869042+intron-Proximal4.4720310.79083K562BUD13
chr1628673722867420+intron-Proximal3.7228110.38328K562SF3B4
chr1628689872869013+intron-Proximal6.3451014.81397K562AQR
chr1628677432867789+intron-Proximal4.139305.41633K562PCBP1
chr1628680142868040+intron-Proximal4.8108313.24177K562AQR
chr1628689762868987+intron-Proximal6.0442812.10660K562AQR
chr1628677472867774+intron-Proximal3.5148110.34961K562AQR
chr1628689702868976+intron-Proximal6.0850413.18785K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PRSS21 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PRSS21 is not available on ENCORE database.

  • 34 RBPs can affect the levels of PRSS21.  








The Knockdown/knockout RNA-Seq assay for PRSS21 is not available on ENCORE database.





34 RBPs can affect the gene expression of PRSS21 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PRSS21ENSG00000007038.61118.84660934.560800.259602.276601.75350K562AGGF1
PRSS21ENSG00000007038.6926.68580673.687900.459905.297103.14700K562AKAP1
PRSS21ENSG00000007038.61203.65390972.442400.307602.153401.57420K562AKAP8L
PRSS21ENSG00000007038.6710.187001331.88000-0.9072012.4695011.35350K562AQR
PRSS21ENSG00000007038.61364.307701020.306300.419105.061103.78440K562ATP5C1
PRSS21ENSG00000007038.61569.514901215.898500.368204.432903.01180K562CPEB4
PRSS21ENSG00000007038.61326.523801065.803300.315602.933701.68490K562DDX21
PRSS21ENSG00000007038.6962.55620682.553100.495804.916903.47330K562DDX3X
PRSS21ENSG00000007038.6893.62110691.997000.368803.336801.86660K562DDX6
PRSS21ENSG00000007038.6553.10850783.21170-0.501804.029002.91050K562EFTUD2
PRSS21ENSG00000007038.6582.62730838.48350-0.525203.702802.48940K562EIF3D
PRSS21ENSG00000007038.6555.96380713.06490-0.359002.086401.36860K562EIF4A3
PRSS21ENSG00000007038.61032.69860742.962300.475002.570101.49110K562FKBP4
PRSS21ENSG00000007038.6786.997501068.15450-0.440703.641402.65640K562FMR1
PRSS21ENSG00000007038.6529.39850741.55160-0.486205.061704.27790K562FXR1
PRSS21ENSG00000007038.6234.61200437.43400-0.898806.285705.12200K562G3BP2
PRSS21ENSG00000007038.6701.221501002.16320-0.515204.843203.79640K562GPKOW
PRSS21ENSG00000007038.62292.843401326.570000.7893014.2092012.46940K562GRSF1
PRSS21ENSG00000007038.61380.558301077.104100.358003.358902.17220K562HNRNPA1
PRSS21ENSG00000007038.6403.90250854.33090-1.080805.716604.88910K562HNRNPC
PRSS21ENSG00000007038.61529.699601137.128800.427804.485003.10210K562HNRNPL
PRSS21ENSG00000007038.61495.976101192.840300.326603.513502.50770K562HNRNPU
PRSS21ENSG00000007038.6786.15940563.630800.480002.355901.43070K562IGF2BP2
PRSS21ENSG00000007038.6971.52690590.731700.717709.536907.71850K562MATR3
PRSS21ENSG00000007038.61483.056901031.351700.523909.235507.84530K562MTPAP
PRSS21ENSG00000007038.6374.91550526.65620-0.490302.636701.68200K562PCBP2
PRSS21ENSG00000007038.61276.792301020.209000.323602.226601.49260K562PPIG
PRSS21ENSG00000007038.6412.61380762.15770-0.885309.561608.16410K562PRPF8
PRSS21ENSG00000007038.61205.869101786.31750-0.566906.652605.38600K562PUF60
PRSS21ENSG00000007038.61113.45250939.669600.244701.804101.30710K562RBM15
PRSS21ENSG00000007038.6931.887801258.18580-0.433104.221602.23250K562RBM17
PRSS21ENSG00000007038.6399.40770551.33020-0.465103.208302.29710K562RBM22
PRSS21ENSG00000007038.6541.91360737.80500-0.445202.774201.75720K562SUPV3L1
PRSS21ENSG00000007038.6645.03300868.67280-0.429403.994703.00400K562SYNCRIP
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PRSS21 is not available on ENCORE database.





6 RBPs can affect the splicing of PRSS21 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSPRSS21ENSG00000007038.6chr16+286867728689702868683286897028678012867967-0.135000.002250.01431shorterK562AQR
MXEPRSS21ENSG00000007038.6chr16+286780128679672868677286897028674302867457287095528711100.179000.000000.000051includedK562UCHL5
MXEPRSS21ENSG00000007038.6chr16+28678012867967286867728689702867430286745728709552871110-0.182000.000000.000002includedK562PUM1
MXEPRSS21ENSG00000007038.6chr16+286780128679672868897286897028674302867457287095528711100.244000.000070.029871includedK562APOBEC3C
MXEPRSS21ENSG00000007038.6chr16+286743028674572868677286897028671802867333287095528710680.124000.003300.099061includedK562HNRNPU
MXEPRSS21ENSG00000007038.6chr16+286780128679672868897286897028674302867457287095528711100.328000.000000.000001includedK562TIA1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PRSS21 is not avaliable on ENCORE database.