PPP1R35

General Information

Gene Name       : PPP1R35
Gene ID             : ENSG00000160813.6
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PPP1R35)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PPP1R35ENSG00000160813.60.333.531.93ENCSR000AEF
HepG2PPP1R35ENSG00000160813.617.396.0711.73ENCSR985KAT
K562PPP1R35ENSG00000160813.624.3613.0518.70ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PPP1R35 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PPP1R35 RNA is bound by 13 proteins.  







eCLIP assay for PPP1R35 is not avaliable on ENCORE database.





13 proteins are bound to PPP1R35 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr7100033970100034077-5'-UTR,CDS,intron-Distal,intron-Proximal3.3118613.61786K562DDX3X
chr7100034023100034060-5'-UTR,intron-Distal,intron-Proximal3.516005.21096K562DDX55
chr7100033988100034096-5'-UTR,CDS,intron-Distal,intron-Proximal3.310745.42487HepG2NCBP2
chr7100033626100033708-CDS,intron-Distal,intron-Proximal3.495406.99312HepG2EFTUD2
chr7100033664100033750-CDS,intron-Distal,intron-Proximal3.084116.56588HepG2SF3B4
chr7100033642100033710-CDS,intron-Distal,intron-Proximal3.236695.08552K562GEMIN5
chr7100033620100033718-CDS,intron-Distal,intron-Proximal3.5569821.68791K562PRPF8
chr7100033518100033551-CDS,intron-Distal5.373087.93248K562RBM15
chr7100033707100033768-CDS,intron-Distal,intron-Proximal4.4850411.17766HepG2PRPF8
chr7100033630100033702-CDS,intron-Distal,intron-Proximal3.9071510.55517K562AQR
chr7100032995100033063-CDS,intron-Distal3.7306210.64078K562PABPC4
chr7100033019100033113-CDS,intron-Distal3.7489912.41857K562DDX55
chr7100033618100033670-CDS,intron-Distal3.247106.54857HepG2PPIG
chr7100033638100033715-CDS,intron-Distal,intron-Proximal3.653549.76884HepG2BUD13
chr7100033641100033699-CDS,intron-Distal,intron-Proximal3.379603.71240HepG2PABPN1
chr7100033551100033574-CDS,intron-Distal5.0202013.84893K562RBM15
chr7100033574100033586-CDS,intron-Distal4.755639.72826K562RBM15
chr7100033691100033741-intron-Distal,intron-Proximal3.793129.97118K562SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PPP1R35 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PPP1R35 is not available on ENCORE database.

  • 66 RBPs can affect the levels of PPP1R35.  








The Knockdown/knockout RNA-Seq assay for PPP1R35 is not available on ENCORE database.





66 RBPs can affect the gene expression of PPP1R35 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PPP1R35ENSG00000160813.276.63270126.91750-0.727902.386801.66700HepG2CALR
PPP1R35ENSG00000160813.2116.18870169.80210-0.547402.331001.71240HepG2CKAP4
PPP1R35ENSG00000160813.2271.08370137.977300.974205.440404.60030HepG2DDX6
PPP1R35ENSG00000160813.2130.2948071.774200.860103.565102.77350HepG2DNAJC21
PPP1R35ENSG00000160813.2128.4050071.159300.851502.740702.09200HepG2DNAJC2
PPP1R35ENSG00000160813.2162.36640316.20380-0.961608.447007.49620HepG2ETF1
PPP1R35ENSG00000160813.2174.09150120.884300.526102.078501.48340HepG2HNRNPL
PPP1R35ENSG00000160813.2205.7334095.146601.112502.423501.32490HepG2KHDRBS1
PPP1R35ENSG00000160813.2262.50900147.938900.827304.378603.55640HepG2MAGOH
PPP1R35ENSG00000160813.2208.22500131.585400.662002.090901.42600HepG2NOL12
PPP1R35ENSG00000160813.2183.4751091.093901.010102.184801.41050HepG2PABPC1
PPP1R35ENSG00000160813.2112.5040071.418100.655502.166001.50640HepG2PPIL4
PPP1R35ENSG00000160813.270.40900154.66870-1.135306.491005.36170HepG2PRPF4
PPP1R35ENSG00000160813.2216.95560133.332600.702304.122503.42970HepG2PUM1
PPP1R35ENSG00000160813.2310.32060206.735200.585903.508102.55270HepG2RBM15
PPP1R35ENSG00000160813.2145.89250264.28460-0.857205.761505.08220HepG2RBM22
PPP1R35ENSG00000160813.2165.1908071.305301.212004.829604.01850HepG2SAFB2
PPP1R35ENSG00000160813.2139.8159067.902601.041903.429602.34950HepG2SMNDC1
PPP1R35ENSG00000160813.270.78030148.40690-1.068104.902704.31940HepG2SRSF1
PPP1R35ENSG00000160813.2112.29810259.15360-1.2065010.759909.87730HepG2SSB
PPP1R35ENSG00000160813.2198.36880141.041200.492002.080501.52630HepG2SUCLG1
PPP1R35ENSG00000160813.244.68800133.37980-1.577608.475007.58140HepG2TAF15
PPP1R35ENSG00000160813.2112.55370195.63220-0.797503.356302.66980HepG2U2AF1
PPP1R35ENSG00000160813.2220.49280129.877400.763502.919002.06050HepG2UBE2L3
PPP1R35ENSG00000160813.2202.17090143.332700.496102.325701.81150HepG2ZNF622
PPP1R35ENSG00000160813.2690.29340551.830200.322902.658502.09890K562AGGF1
PPP1R35ENSG00000160813.2267.73770550.61250-1.040209.682908.69000K562AQR
PPP1R35ENSG00000160813.2841.01980602.497400.481105.363704.04280K562ATP5C1
PPP1R35ENSG00000160813.2501.15560844.35160-0.7526010.192508.38060K562CELF1
PPP1R35ENSG00000160813.2441.53860312.820700.497103.720302.13940K562DDX6
PPP1R35ENSG00000160813.2204.61160353.09330-0.787203.485101.49200K562DNAJC2
PPP1R35ENSG00000160813.2435.34500331.953200.391102.487501.79890K562EIF2S2
PPP1R35ENSG00000160813.2451.89340686.54050-0.603406.058704.68570K562EIF4G2
PPP1R35ENSG00000160813.2308.75310211.162500.548002.892302.02460K562FIP1L1
PPP1R35ENSG00000160813.2187.04370291.00230-0.637703.377002.42800K562FMR1
PPP1R35ENSG00000160813.28.3141076.25590-3.197208.925907.50960K562G3BP2
PPP1R35ENSG00000160813.2313.05930456.78360-0.545104.311402.89410K562GLRX3
PPP1R35ENSG00000160813.2322.49450495.71650-0.620204.715503.32610K562HNRNPA1
PPP1R35ENSG00000160813.2136.29420296.06030-1.119208.589807.58960K562HNRNPC
PPP1R35ENSG00000160813.2499.10870286.277300.801806.771905.53650K562HSPD1
PPP1R35ENSG00000160813.2339.60770171.607100.984703.981202.66020K562IGF2BP2
PPP1R35ENSG00000160813.2250.94840174.551300.523602.660501.49920K562IGF2BP3
PPP1R35ENSG00000160813.2216.40860441.09810-1.027305.797403.68990K562ILF2
PPP1R35ENSG00000160813.2147.96490233.16100-0.656102.477601.59760K562KRR1
PPP1R35ENSG00000160813.2398.45210264.141600.593003.683001.84900K562LSM11
PPP1R35ENSG00000160813.2250.85660180.361400.475902.130601.38870K562MAGOH
PPP1R35ENSG00000160813.2747.89390583.324300.358402.548701.53170K562MAK16
PPP1R35ENSG00000160813.2247.76680179.996800.460902.121101.32270K562MATR3
PPP1R35ENSG00000160813.2507.91750731.75160-0.526804.136602.75560K562MSI2
PPP1R35ENSG00000160813.2356.40750480.25050-0.430303.156702.29390K562MTPAP
PPP1R35ENSG00000160813.2455.15010291.599400.642304.015302.14790K562NUSAP1
PPP1R35ENSG00000160813.2224.51580437.72500-0.963202.651501.83890K562PCBP3
PPP1R35ENSG00000160813.2198.49250335.71770-0.758203.043902.20320K562POLR2G
PPP1R35ENSG00000160813.2453.50720239.725700.919604.418203.34840K562PPIG
PPP1R35ENSG00000160813.2418.34090265.467100.656004.439703.25090K562PSIP1
PPP1R35ENSG00000160813.2344.50970175.231700.975209.084207.92700K562PTBP1
PPP1R35ENSG00000160813.2533.56360749.04150-0.489402.550601.76810K562PUF60
PPP1R35ENSG00000160813.2478.24810796.90800-0.736707.062905.30330K562PUM1
PPP1R35ENSG00000160813.2232.75610168.031200.470002.036301.31990K562RBM22
PPP1R35ENSG00000160813.2255.57600176.824800.531302.306301.32820K562NELFE
PPP1R35ENSG00000160813.2272.58550430.92880-0.660702.950801.30690K562RPS3A
PPP1R35ENSG00000160813.2257.49400154.717700.734803.234102.14320K562RPS3
PPP1R35ENSG00000160813.2163.80390259.69670-0.664902.950201.94480K562SF3B1
PPP1R35ENSG00000160813.2349.55040229.676700.605803.508902.31840K562SRFBP1
PPP1R35ENSG00000160813.2383.92610539.44750-0.490704.507903.34610K562SRPK2
PPP1R35ENSG00000160813.2267.15190171.784500.637003.392202.61480K562SRSF1
PPP1R35ENSG00000160813.2276.77700149.364300.889805.287903.74690K562SRSF4
PPP1R35ENSG00000160813.2324.26310162.235000.999008.150706.25140K562SRSF5
PPP1R35ENSG00000160813.220.3828074.84420-1.876504.499802.47910K562TAF15
PPP1R35ENSG00000160813.2373.44640173.859301.1029010.123508.63630K562TARDBP
PPP1R35ENSG00000160813.2377.57650167.706301.170709.733108.08220K562TIA1
PPP1R35ENSG00000160813.2336.07530164.564601.030008.248806.07920K562TRA2A
PPP1R35ENSG00000160813.244.2741076.24570-0.784202.045901.35610K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PPP1R35 is not available on ENCORE database.





11 RBPs can affect the splicing of PPP1R35 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPPP1R35ENSG00000160813.2chr7-100033253100033390100032904100033156100033470100033687-0.216000.001620.05326excludedK562PRPF8
SEPPP1R35ENSG00000160813.2chr7-100033253100033390100032904100033156100033470100033687-0.375000.000000.00000excludedHepG2U2AF1
SEPPP1R35ENSG00000160813.2chr7-100033253100033390100032904100033156100033470100033687-0.346000.000000.00013excludedHepG2U2AF2
SEPPP1R35ENSG00000160813.2chr7-100033253100033390100032904100033156100033470100033687-0.396000.000000.00000excludedK562FXR1
SEPPP1R35ENSG00000160813.2chr7-100033253100033390100032904100033156100033470100033687-0.075000.001460.08336excludedK562HNRNPL
SEPPP1R35ENSG00000160813.2chr7-1000332531000333901000329041000331561000334701000336870.099000.000020.00413includedK562HNRNPUL1
SEPPP1R35ENSG00000160813.2chr7-100033253100033390100032904100033156100033470100033687-0.132000.000150.03930excludedK562SAFB
SEPPP1R35ENSG00000160813.2chr7-100033253100033390100032904100033156100033470100033687-0.169000.001670.05933excludedK562PTBP1
SEPPP1R35ENSG00000160813.2chr7-100033253100033390100032904100033156100033470100033687-0.137000.000640.01318excludedK562HNRNPC
RIPPP1R35ENSG00000160813.2chr7-1000332531000336871000332531000333901000334701000336870.130000.002110.09795includedK562EIF4G2
RIPPP1R35ENSG00000160813.2chr7-1000332531000336871000332531000333901000334701000336870.527000.000000.00000includedHepG2U2AF1
RIPPP1R35ENSG00000160813.2chr7-1000332531000336871000332531000333901000334701000336870.218000.007640.06233includedHepG2RBM22

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PPP1R35 is not avaliable on ENCORE database.