NPHP3

General Information

Gene Name       : NPHP3
Gene ID             : ENSG00000113971.19
Essential Gene : No

Functions

Localization

Domains (AlphaFold: NPHP3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NPHP3ENSG00000113971.193.112.742.92ENCSR000AEF
HepG2NPHP3ENSG00000113971.194.657.936.29ENCSR985KAT
K562NPHP3ENSG00000113971.194.343.884.11ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NPHP3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • NPHP3 RNA is bound by 20 proteins.  







eCLIP assay for NPHP3 is not avaliable on ENCORE database.





20 proteins are bound to NPHP3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3132350260132350315-3'-UTR,5'-UTR,CDS,intron-Distal3.7095631.44978HepG2BCLAF1
chr3132278726132278783-3'-UTR,CDS,intron-Distal3.093119.00189HepG2BCLAF1
chr3132277113132277194-3'-UTR,intron-Distal3.707237.19109HepG2LSM11
chr3132298258132298403-3'-UTR,CDS,intron-Distal,intron-Proximal3.3549210.06183HepG2GRWD1
chr3132278679132278786-3'-UTR,CDS,intron-Distal4.3844113.64823HepG2PPIG
chr3132298367132298403-3'-UTR,CDS,intron-Distal,intron-Proximal3.9503518.23418HepG2BCLAF1
chr3132278692132278787-3'-UTR,CDS,intron-Distal,intron-Proximal4.0307711.30875HepG2PABPN1
chr3132295786132295843-3'-UTR,CDS,intron-Distal,intron-Proximal4.1072028.80518HepG2BCLAF1
chr3132338311132338355-3'-UTR,CDS,intron-Distal,intron-Proximal4.3841811.99763HepG2BCLAF1
chr3132337590132337615-3'-UTR,CDS,intron-Distal,intron-Proximal3.011438.27894HepG2BCLAF1
chr3132294658132294667-3'-UTR,CDS,intron-Distal3.263853.94979HepG2BCLAF1
chr3132322097132322164-3'-UTR,CDS,intron-Distal3.9137315.13430HepG2PPIG
chr3132347270132347290-3'-UTR,5'-UTR,CDS,intron-Distal3.756608.66838HepG2BCLAF1
chr3132322109132322143-3'-UTR,CDS,intron-Distal3.9104413.85216HepG2GRWD1
chr3132323939132323993-3'-UTR,CDS,intron-Distal,intron-Proximal3.437709.24355HepG2PPIG
chr3132277545132277676-3'-UTR,intron-Distal,intron-Proximal3.0485411.31568HepG2ZC3H11A
chr3132277154132277176-3'-UTR,intron-Distal3.287864.85828HepG2BCLAF1
chr3132322143132322162-3'-UTR,CDS,intron-Distal3.395907.75618HepG2GRWD1
chr3132277039132277088-3'-UTR,intron-Distal3.476833.64832HepG2ZC3H11A
chr3132322074132322086-3'-UTR,CDS,intron-Distal4.3072415.30407HepG2BCLAF1
chr3132358390132358472-3'-UTR,5'-UTR,CDS,intron-Distal4.3289218.33118HepG2BCLAF1
chr3132279950132279984-3'-UTR,CDS,intron-Distal4.0137610.98590HepG2BCLAF1
chr3132277219132277277-3'-UTR,intron-Distal,intron-Proximal3.887117.91102HepG2LSM11
chr3132338311132338390-3'-UTR,CDS,intron-Distal,intron-Proximal3.616243.23099HepG2UCHL5
chr3132338310132338370-3'-UTR,CDS,intron-Distal,intron-Proximal3.497284.16915HepG2HLTF
chr3132278676132278787-3'-UTR,CDS,intron-Distal,intron-Proximal3.064393.92610HepG2GRWD1
chr3132277819132277863-3'-UTR,CDS,intron-Distal4.225993.55598HepG2ZC3H11A
chr3132277246132277302-3'-UTR,intron-Distal,intron-Proximal4.058835.50789HepG2EIF3H
chr3132322071132322097-3'-UTR,CDS,intron-Distal,intron-Proximal4.8790520.47584HepG2PPIG
chr3132277823132277918-3'-UTR,CDS,intron-Distal3.340847.42509HepG2PABPN1
chr3132349279132349316-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.0335114.52112HepG2BCLAF1
chr3132323993132324051-3'-UTR,CDS,intron-Distal,intron-Proximal3.832069.05563HepG2PPIG
chr3132322164132322171-3'-UTR,CDS,intron-Distal3.372828.43208HepG2BCLAF1
chr3132277676132277724-3'-UTR,intron-Distal4.536744.66971HepG2ZC3H11A
chr3132298298132298367-3'-UTR,CDS,intron-Distal,intron-Proximal4.2598214.75464HepG2BCLAF1
chr3132322090132322109-3'-UTR,CDS,intron-Distal3.9212211.26222HepG2GRWD1
chr3132423058132423086-3'-UTR,CDS,intron-Distal3.895367.58784HepG2BCLAF1
chr3132358334132358390-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal5.3499234.50464HepG2BCLAF1
chr3132298323132298374-3'-UTR,CDS,intron-Distal,intron-Proximal4.6669812.79935HepG2PRPF8
chr3132279984132280042-3'-UTR,CDS,intron-Distal3.1785414.80413HepG2BCLAF1
chr3132277117132277199-3'-UTR,intron-Distal3.7184610.84321HepG2ZC3H11A
chr3132358401132358501-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.834644.16554HepG2PPIG
chr3132279944132279987-3'-UTR,CDS,intron-Distal,intron-Proximal3.829223.08510HepG2ZC3H11A
chr3132277205132277329-3'-UTR,intron-Distal,intron-Proximal4.2911612.83752HepG2PABPN1
chr3132280011132280067-3'-UTR,CDS,intron-Distal,intron-Proximal4.1444710.72269HepG2PPIG
chr3132297996132298063-3'-UTR,intron-Distal,intron-Proximal3.293048.24411HepG2KHSRP
chr3132297644132297666-3'-UTR,CDS,intron-Distal,intron-Proximal3.583556.20035HepG2BCLAF1
chr3132358334132358401-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.841485.90680HepG2PPIG
chr3132322104132322164-3'-UTR,CDS,intron-Distal3.7517422.36185HepG2BCLAF1
chr3132350183132350255-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.8701929.28846HepG2BCLAF1
chr3132322072132322074-3'-UTR,CDS,intron-Distal,intron-Proximal4.2208214.75464HepG2BCLAF1
chr3132350315132350323-3'-UTR,5'-UTR,CDS,intron-Distal4.0479418.33962HepG2BCLAF1
chr3132322069132322103-3'-UTR,CDS,intron-Distal,intron-Proximal3.848516.65791HepG2BUD13
chr3132278676132278787-3'-UTR,CDS,intron-Distal,intron-Proximal4.1126912.30399HepG2LSM11
chr3132298375132298403-3'-UTR,CDS,intron-Distal,intron-Proximal4.7126816.67786HepG2PPIG
chr3132298253132298298-3'-UTR,intron-Distal,intron-Proximal3.638248.74800HepG2BCLAF1
chr3132323941132323989-3'-UTR,CDS,intron-Distal,intron-Proximal3.061525.81107HepG2GRWD1
chr3132297698132297769-3'-UTR,CDS,intron-Distal,intron-Proximal4.311915.63851K562SF3B4
chr3132400557132400693-3'-UTR,intron-Distal,intron-Proximal4.418094.76003K562KHSRP
chr3132277138132277205-3'-UTR,intron-Distal3.268657.42509HepG2PABPN1
chr3132279944132280011-3'-UTR,CDS,intron-Distal,intron-Proximal3.582258.54450HepG2PPIG
chr3132295843132295855-3'-UTR,CDS,intron-Distal4.6878410.19430HepG2BCLAF1
chr3132413692132413728-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.359826.74947HepG2BCLAF1
chr3132345534132345569-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.7844311.54096HepG2BCLAF1
chr3132347183132347237-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.8475715.55279HepG2BCLAF1
chr3132337476132337512-3'-UTR,CDS,intron-Distal,intron-Proximal3.0626610.32758HepG2BCLAF1
chr3132294705132294759-3'-UTR,CDS,intron-Distal3.591489.02617HepG2PPIG
chr3132277818132277880-3'-UTR,CDS,intron-Distal3.349166.78262HepG2LSM11
chr3132322086132322104-3'-UTR,CDS,intron-Distal4.0428915.00162HepG2BCLAF1
chr3132297852132297914-3'-UTR,CDS,intron-Distal,intron-Proximal3.486633.93230HepG2U2AF1
chr3132298225132298364-3'-UTR,CDS,intron-Distal,intron-Proximal5.8860840.45379HepG2EFTUD2
chr3132323988132324050-3'-UTR,CDS,intron-Distal,intron-Proximal3.4015011.79442HepG2BCLAF1
chr3132349360132349402-3'-UTR,5'-UTR,CDS,intron-Distal4.2283014.68146HepG2BCLAF1
chr3132295786132295858-3'-UTR,CDS,intron-Distal,intron-Proximal3.9275812.11762HepG2PPIG
chr3132322072132322090-3'-UTR,CDS,intron-Distal,intron-Proximal4.115288.70622HepG2GRWD1
chr3132294614132294687-3'-UTR,CDS,intron-Distal,intron-Proximal3.034915.54641HepG2PPIG
chr3132297860132297919-3'-UTR,CDS,intron-Distal,intron-Proximal5.0914231.67714HepG2U2AF2
chr3132298069132298185-3'-UTR,intron-Distal3.6366512.98026HepG2KHSRP
chr3132277605132277674-3'-UTR,intron-Distal,intron-Proximal4.044918.92128HepG2LSM11
chr3132323993132324059-3'-UTR,CDS,intron-Distal,intron-Proximal3.379486.61645HepG2BUD13
chr3132278679132278703-3'-UTR,CDS,intron-Distal3.730927.83567HepG2BCLAF1
chr3132323941132323976-3'-UTR,CDS,intron-Distal,intron-Proximal3.2524910.21526HepG2BCLAF1
chr3132277909132277928-3'-UTR,CDS,intron-Distal3.583913.51117HepG2LSM11
chr3132358413132358479-3'-UTR,5'-UTR,CDS,intron-Distal3.442335.14253HepG2GRWD1
chr3132298246132298323-3'-UTR,intron-Distal,intron-Proximal4.6915014.13124HepG2PRPF8
chr3132361520132361556-5'-UTR,CDS,intron-Distal,intron-Proximal4.427424.68960HepG2ZC3H11A
chr3132360958132360978-5'-UTR,CDS,intron-Distal,intron-Proximal4.261523.88553HepG2ZC3H11A
chr3132361520132361544-5'-UTR,CDS,intron-Distal,intron-Proximal3.187847.61291HepG2BCLAF1
chr3132360816132360949-5'-UTR,CDS,intron-Distal3.659896.51392HepG2EIF3H
chr3132360950132360977-5'-UTR,CDS,intron-Distal3.4279110.08874HepG2BCLAF1
chr3132363726132363738-5'-UTR,CDS,intron-Distal,intron-Proximal3.545145.76104HepG2BCLAF1
chr3132363657132363719-5'-UTR,CDS,intron-Distal3.9225911.19453HepG2BCLAF1
chr3132360820132360882-5'-UTR,CDS,intron-Distal3.7338212.82131HepG2BCLAF1
chr3132360892132360950-5'-UTR,CDS,intron-Distal4.7212816.52049HepG2BCLAF1
chr3132360819132360882-5'-UTR,CDS,intron-Distal3.498564.27261HepG2GRWD1
chr3132361558132361616-5'-UTR,CDS,intron-Distal4.4337716.88216HepG2BCLAF1
chr3132435614132435661-5'-UTR,CDS,intron-Distal,intron-Proximal4.384414.50440HepG2PPIG
chr3132437847132437891-CDS,intron-Distal4.185044.23295HepG2GRWD1
chr3132437949132437980-CDS,intron-Distal5.276508.75808HepG2BCLAF1
chr3132332695132332749-intron-Distal3.903793.01456K562EXOSC5
chr3132313357132313432-intron-Distal4.286523.29248HepG2SUGP2
chr3132378533132378639-5'-UTR,CDS,intron-Distal,intron-Proximal3.114344.86573HepG2EIF3H
chr3132326945132327018-intron-Distal4.159983.96879HepG2MATR3
chr3132437673132437796-intron-Distal,intron-Proximal3.252834.52210K562KHSRP
chr3132415387132415449-intron-Distal5.296308.71243HepG2QKI
chr3132413979132414063-intron-Distal,intron-Proximal3.737485.09669HepG2QKI
chr3132325877132325978-intron-Distal4.022013.62238HepG2MATR3
chr3132378445132378512-5'-UTR,CDS,intron-Distal,intron-Proximal3.5990213.90271HepG2BCLAF1
chr3132414087132414151-intron-Distal,intron-Proximal5.1091615.81546HepG2QKI
chr3132378415132378495-5'-UTR,CDS,intron-Distal,intron-Proximal4.110565.93840HepG2PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NPHP3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NPHP3 is not available on ENCORE database.

  • 54 RBPs can affect the levels of NPHP3.  








The Knockdown/knockout RNA-Seq assay for NPHP3 is not available on ENCORE database.





54 RBPs can affect the gene expression of NPHP3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NPHP3ENSG00000113971.14489.22410599.41650-0.293102.062701.38700HepG2AKAP8L
NPHP3ENSG00000113971.14456.98900596.49490-0.384403.462302.73380HepG2CKAP4
NPHP3ENSG00000113971.14613.60650742.48530-0.275002.047201.47930HepG2CELF1
NPHP3ENSG00000113971.14302.32500425.00680-0.491404.212403.43970HepG2DNAJC2
NPHP3ENSG00000113971.14773.06370409.746000.915809.439108.38280HepG2EIF2S1
NPHP3ENSG00000113971.14685.23080452.786700.597704.144003.36650HepG2EIF4A3
NPHP3ENSG00000113971.14782.49730440.910200.827506.040305.05280HepG2EIF4B
NPHP3ENSG00000113971.14599.81170268.112001.1616015.4905013.69750HepG2FUBP3
NPHP3ENSG00000113971.14656.54400423.826100.631304.647603.79570HepG2G3BP1
NPHP3ENSG00000113971.14717.20860450.009800.672305.657004.37180HepG2G3BP2
NPHP3ENSG00000113971.14777.90080481.485100.692006.737405.69400HepG2HNRNPC
NPHP3ENSG00000113971.14582.84040429.276800.441102.634201.95180HepG2HNRNPK
NPHP3ENSG00000113971.14589.62700727.30620-0.302802.763902.09060HepG2HNRNPL
NPHP3ENSG00000113971.14342.78620478.30070-0.480604.020503.30050HepG2HNRNPU
NPHP3ENSG00000113971.14688.90420404.350500.768602.349801.45060HepG2IGF2BP3
NPHP3ENSG00000113971.14701.19880433.336300.694204.649003.31830HepG2KHSRP
NPHP3ENSG00000113971.14596.29410457.096000.383401.977801.41880HepG2MAGOH
NPHP3ENSG00000113971.14547.10040791.69780-0.533105.804604.70600HepG2NOL12
NPHP3ENSG00000113971.14652.56250435.915100.582004.492903.54450HepG2NSUN2
NPHP3ENSG00000113971.14618.96410411.695600.588206.151305.39870HepG2PTBP1
NPHP3ENSG00000113971.14398.79480755.72950-0.9222011.9802010.85850HepG2PUF60
NPHP3ENSG00000113971.14574.87220802.22230-0.480806.363405.54140HepG2PUM1
NPHP3ENSG00000113971.14885.32190445.920200.9893016.0812014.75350HepG2QKI
NPHP3ENSG00000113971.14626.69800404.684700.630905.511304.58950HepG2RBM25
NPHP3ENSG00000113971.14603.58220458.194700.397502.907302.35480HepG2NELFE
NPHP3ENSG00000113971.14650.15530426.715200.607406.497505.60960HepG2RECQL
NPHP3ENSG00000113971.14701.43500428.665000.710408.909907.94060HepG2SF3B4
NPHP3ENSG00000113971.14745.46670541.454500.461202.101001.42350HepG2SNRNP70
NPHP3ENSG00000113971.14825.48800447.418500.8835014.4845013.58310HepG2SRSF1
NPHP3ENSG00000113971.14533.91470746.15130-0.482905.359304.52960HepG2SRSF5
NPHP3ENSG00000113971.14942.14150789.311200.255202.202101.73190HepG2SSB
NPHP3ENSG00000113971.14955.47460402.115601.2485027.6888026.15120HepG2TAF15
NPHP3ENSG00000113971.14688.29300369.533600.897205.734104.54240HepG2TIA1
NPHP3ENSG00000113971.14503.51960630.99700-0.325602.463701.89140HepG2UTP3
NPHP3ENSG00000113971.14572.05450718.80330-0.329403.153402.58170HepG2ZNF622
NPHP3ENSG00000113971.14373.33820508.10180-0.444602.710801.48180K562APOBEC3C
NPHP3ENSG00000113971.14295.14860423.45990-0.520803.999403.23520K562DDX47
NPHP3ENSG00000113971.14156.12900294.54980-0.915806.796705.56200K562EIF3G
NPHP3ENSG00000113971.14275.13460189.600800.537102.380501.34660K562FKBP4
NPHP3ENSG00000113971.14211.19680316.17790-0.582103.709203.02380K562FXR1
NPHP3ENSG00000113971.14224.63050340.17120-0.598703.383102.54910K562GRSF1
NPHP3ENSG00000113971.14402.07310218.278500.881207.209106.28990K562HNRNPC
NPHP3ENSG00000113971.14115.40370192.88620-0.741102.979702.01040K562HNRNPM
NPHP3ENSG00000113971.14201.48260125.606300.681602.988001.43350K562ILF3
NPHP3ENSG00000113971.14318.65530423.52980-0.410502.420301.63120K562MAGOH
NPHP3ENSG00000113971.14294.09960422.68790-0.523303.642402.57040K562MATR3
NPHP3ENSG00000113971.1498.09700191.17500-0.962602.725101.98160K562PRPF8
NPHP3ENSG00000113971.14250.90080411.47720-0.713706.101405.14690K562PTBP1
NPHP3ENSG00000113971.14284.21820394.61980-0.473502.767701.92740K562RBM22
NPHP3ENSG00000113971.14206.00640326.03640-0.662303.213002.12500K562RPS3
NPHP3ENSG00000113971.14475.35460307.682100.627504.315302.58580K562SSRP1
NPHP3ENSG00000113971.14438.61790281.412800.640204.115402.53440K562STAU1
NPHP3ENSG00000113971.14130.41980186.27300-0.514302.048601.34060K562SYNCRIP
NPHP3ENSG00000113971.14293.64070408.26640-0.475502.675301.97770K562TARDBP
NPHP3ENSG00000113971.14260.94240386.38110-0.566303.388302.15520K562TRA2A
NPHP3ENSG00000113971.14446.39400350.542400.348602.206501.56050K562UPF1
NPHP3ENSG00000113971.14402.15580299.943700.423002.500201.66540K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NPHP3 is not available on ENCORE database.





13 RBPs can affect the splicing of NPHP3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENPHP3ENSG00000113971.14chr3-1324155741324156571324136701324138091324161031324162060.848000.000000.00000includedK562SRSF1
SENPHP3ENSG00000113971.14chr3-132436798132436961132435600132435753132437837132437988-0.634000.001630.03097excludedK562SRSF1
SENPHP3ENSG00000113971.14chr3-1324181961324182941324161031324162061324187611324189050.608000.000030.00429includedHepG2AKAP1
SENPHP3ENSG00000113971.14chr3-1324155741324156571324136701324138091324161031324162060.518000.000720.03967includedHepG2PTBP1
SENPHP3ENSG00000113971.14chr3-1324181961324182941324161031324162061324187611324189050.452000.000480.01409includedHepG2SRSF1
SENPHP3ENSG00000113971.14chr3-1324155741324156571324136701324138091324161031324162060.634000.000000.00001includedHepG2SRSF1
SENPHP3ENSG00000113971.14chr3-132415574132415657132413670132413809132416103132416206-0.226000.000820.08198excludedHepG2RBFOX2
SENPHP3ENSG00000113971.14chr3-1324155741324156571324136701324138091324161031324162060.410000.000150.02206includedHepG2TAF15
SENPHP3ENSG00000113971.14chr3-132405994132406070132405103132405231132407493132407735-0.196000.001360.03450excludedK562RBM15
SENPHP3ENSG00000113971.14chr3-132405994132406070132405103132405231132407493132407735-0.170000.004510.08598excludedK562AGGF1
SENPHP3ENSG00000113971.14chr3-1324181961324182941324161031324162061324187611324189050.659000.000000.00035includedHepG2HNRNPC
SENPHP3ENSG00000113971.14chr3-1324155741324156571324136701324138091324161031324162060.472000.000050.00357includedHepG2HNRNPC
SENPHP3ENSG00000113971.14chr3-1324155741324156571324136701324138091324161031324162060.593000.000280.01509includedK562PTBP1
A3SSNPHP3ENSG00000113971.14chr3-1324191771324193861324191771324192921324202731324203770.149000.013890.07005longerK562AQR
RINPHP3ENSG00000113971.14chr3-1324033971324052311324033971324036381324051031324052310.346000.003270.03861includedHepG2PRPF8
RINPHP3ENSG00000113971.14chr3-1324033971324052311324033971324036381324051031324052310.433000.001080.08778includedK562HNRNPK
RINPHP3ENSG00000113971.14chr3-1324033971324052311324033971324036381324051031324052310.502000.013480.09923includedHepG2U2AF1
MXENPHP3ENSG00000113971.14chr3-1324022421324023681324033971324052311324015461324016621324059941324060700.308000.000740.025661includedK562PPIL4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NPHP3 is not avaliable on ENCORE database.