MRC2

General Information

Gene Name       : MRC2
Gene ID             : ENSG00000011028.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MRC2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MRC2ENSG00000011028.130.000.200.10ENCSR000AEF
HepG2MRC2ENSG00000011028.130.000.000.00ENCSR985KAT
K562MRC2ENSG00000011028.137.004.475.73ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MRC2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MRC2 RNA is bound by 5 proteins.  







eCLIP assay for MRC2 is not avaliable on ENCORE database.





5 proteins are bound to MRC2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr176076982960769934+3'-UTR3.038594.75678K562METAP2
chr176077073260770776+3'-UTR3.268933.25727K562METAP2
chr176077061460770697+3'-UTR5.2836217.60288K562UPF1
chr176076981160769866+3'-UTR3.605166.40324K562UPF1
chr176077022360770281+3'-UTR4.460418.17454K562UPF1
chr176077072760770778+3'-UTR4.769869.54560K562UPF1
chr176077022960770295+3'-UTR3.829813.85485K562AKAP1
chr176077009060770142+3'-UTR5.171146.29854K562UPF1
chr176077029560770367+3'-UTR4.249549.71169K562UPF1
chr176076982460769902+3'-UTR4.625575.24155K562BUD13
chr176076587560765935+3'-UTR,CDS4.761436.02674K562UPF1
chr176076986660769986+3'-UTR5.6004620.80348K562UPF1
chr176077036760770605+3'-UTR4.8578636.48471K562UPF1
chr176077002560770070+3'-UTR4.335948.51603K562UPF1
chr176076804460768105+CDS4.982616.99975K562UPF1
chr176076651160766573+intron-Distal4.003713.56076K562BUD13
chr176076632160766383+intron-Proximal4.831155.65342K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MRC2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MRC2 is not available on ENCORE database.

  • 65 RBPs can affect the levels of MRC2.  








The Knockdown/knockout RNA-Seq assay for MRC2 is not available on ENCORE database.





65 RBPs can affect the gene expression of MRC2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MRC2ENSG00000011028.922.037000.480605.518705.367804.53350HepG2DDX6
MRC2ENSG00000011028.9277.84960430.19990-0.630703.417502.09010K562AARS
MRC2ENSG00000011028.9922.395001165.33180-0.337303.504502.87820K562AGGF1
MRC2ENSG00000011028.9556.77110399.374400.479204.174002.98020K562BCLAF1
MRC2ENSG00000011028.9469.19960302.985000.630905.034703.54480K562CSTF2
MRC2ENSG00000011028.91275.67880690.086800.8863019.0327016.00780K562DDX21
MRC2ENSG00000011028.9556.62410350.191500.668507.745705.52990K562DDX27
MRC2ENSG00000011028.91149.54260798.955800.524803.503602.78250K562DDX47
MRC2ENSG00000011028.9930.912301304.80430-0.487106.661605.21100K562DKC1
MRC2ENSG00000011028.9333.61900507.68880-0.605704.363002.64810K562DNAJC21
MRC2ENSG00000011028.91159.86470349.611001.7300015.0775012.38190K562EEF2
MRC2ENSG00000011028.9639.59730337.627000.921603.119302.14660K562EFTUD2
MRC2ENSG00000011028.9491.99620605.44890-0.299402.066601.42910K562EIF2S2
MRC2ENSG00000011028.9627.83810361.216500.797402.430001.46750K562EIF3D
MRC2ENSG00000011028.9296.38490192.571700.622003.743402.82760K562EIF3G
MRC2ENSG00000011028.9636.68340390.936900.703503.759501.51150K562EIF3H
MRC2ENSG00000011028.91263.404801000.426000.336602.941101.97320K562EIF4G2
MRC2ENSG00000011028.9972.00660439.871001.143805.412604.20120K562FIP1L1
MRC2ENSG00000011028.921.53450135.55310-2.654106.899805.67030K562G3BP2
MRC2ENSG00000011028.9897.34920683.828300.391903.770902.44760K562GLRX3
MRC2ENSG00000011028.9610.75640323.288600.917707.166605.88800K562GPKOW
MRC2ENSG00000011028.91006.89900806.766200.319602.144701.47380K562GRSF1
MRC2ENSG00000011028.91344.67500745.866200.8502015.1203012.92900K562HNRNPA1
MRC2ENSG00000011028.91512.58380470.380501.6850047.0465044.71710K562HNRNPC
MRC2ENSG00000011028.91431.87220826.022000.7936015.9649013.91650K562HNRNPU
MRC2ENSG00000011028.9807.49550596.292700.437302.617801.84270K562HSPD1
MRC2ENSG00000011028.9576.39710298.828000.947608.092105.97750K562IGF2BP2
MRC2ENSG00000011028.9557.41280313.202700.831504.566503.35420K562MATR3
MRC2ENSG00000011028.9996.924501441.58990-0.532106.319704.83820K562MBNL1
MRC2ENSG00000011028.9892.85670718.956500.312402.983202.14470K562MTPAP
MRC2ENSG00000011028.9660.804201010.45120-0.612704.215703.06010K562NAA15
MRC2ENSG00000011028.9340.27440477.35820-0.488403.374002.00830K562NCBP2
MRC2ENSG00000011028.91221.64030798.823600.612809.220007.96550K562NSUN2
MRC2ENSG00000011028.9432.06900304.956600.502603.525802.78680K562PTBP1
MRC2ENSG00000011028.9910.352901091.49910-0.261802.005101.30970K562PUF60
MRC2ENSG00000011028.9729.512801161.27240-0.6707010.066807.97470K562PUM1
MRC2ENSG00000011028.9762.913201137.51920-0.576308.285806.59910K562PUM2
MRC2ENSG00000011028.9751.773701202.52450-0.677707.000306.18220K562PUS1
MRC2ENSG00000011028.91066.82300765.175300.479403.176201.44710K562RBM17
MRC2ENSG00000011028.9442.73900285.029200.635204.319002.45250K562RBM34
MRC2ENSG00000011028.9595.94430385.030000.630105.596604.18080K562RCC2
MRC2ENSG00000011028.9602.11930334.469400.848102.424301.66140K562RPS19
MRC2ENSG00000011028.9584.59200303.939100.943508.098506.27390K562RPS3
MRC2ENSG00000011028.9917.03330557.320300.718404.434802.40790K562SBDS
MRC2ENSG00000011028.91046.70110667.749300.648406.863904.60900K562SDAD1
MRC2ENSG00000011028.9287.08870614.30480-1.097504.765703.05000K562SF1
MRC2ENSG00000011028.9504.27750364.977100.466302.810401.77680K562SRFBP1
MRC2ENSG00000011028.9532.61560293.375100.860207.999006.08170K562SRSF4
MRC2ENSG00000011028.9495.10910282.416700.809807.458905.63030K562SRSF5
MRC2ENSG00000011028.9937.01640615.779600.605608.834006.74700K562SRSF7
MRC2ENSG00000011028.9561.42910317.751400.821102.764501.74980K562SUPV3L1
MRC2ENSG00000011028.9461.67780727.03870-0.655107.316705.96610K562SYNCRIP
MRC2ENSG00000011028.9704.59980302.542001.219604.210403.33190K562TARDBP
MRC2ENSG00000011028.9592.43610291.847901.0213013.1468011.24270K562TIA1
MRC2ENSG00000011028.9772.13840405.664500.928509.874008.00740K562TIAL1
MRC2ENSG00000011028.9539.24610286.497500.912309.357607.00210K562TRA2A
MRC2ENSG00000011028.91492.540701083.575000.461904.195102.63240K562TROVE2
MRC2ENSG00000011028.951.02160131.13500-1.361903.079401.91530K562U2AF1
MRC2ENSG00000011028.9688.58590336.482301.033004.848403.46050K562UCHL5
MRC2ENSG00000011028.9576.83430791.71020-0.456804.008901.97310K562UPF2
MRC2ENSG00000011028.9487.02730744.75310-0.612804.938603.33480K562UTP3
MRC2ENSG00000011028.91083.24450724.759300.579706.877405.45870K562WDR3
MRC2ENSG00000011028.91226.35340753.667000.7023015.4057013.62720K562WDR43
MRC2ENSG00000011028.91558.686901092.941500.512005.745904.42880K562ZC3H8
MRC2ENSG00000011028.91009.06650772.998300.384403.397001.34810K562ZNF800
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MRC2 is not available on ENCORE database.





3 RBPs can affect the splicing of MRC2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
MXEMRC2ENSG00000011028.9chr17+6076564960765764607658616076602560759595607597386076621260766321-0.262000.002620.040672includedK562SRSF1
MXEMRC2ENSG00000011028.9chr17+6075941660759738607656496076576460758818607592986076586160766025-0.060000.000390.065142includedK562ZC3H8
MXEMRC2ENSG00000011028.9chr17+6076586160766025607662126076632160765649607657646076688260767121-0.192000.000980.022882includedK562PRPF8

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MRC2 is not avaliable on ENCORE database.