MEIS2

General Information

Gene Name : MEIS2
Gene ID : ENSG00000134138.19
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: MEIS2)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	MEIS2	ENSG00000134138.19	30.89	36.73	33.81	ENCSR000AEF
HepG2	MEIS2	ENSG00000134138.19	13.44	12.58	13.01	ENCSR985KAT
K562	MEIS2	ENSG00000134138.19	37.23	43.19	40.21	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for MEIS2 is not avaliable on ENCORE database.

Proteins bound to RNA

MEIS2 RNA is bound by 15 proteins.

eCLIP assay for MEIS2 is not avaliable on ENCORE database.

15 proteins are bound to MEIS2 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr15	37184059	37184171	-	3'-UTR,intron-Distal,intron-Proximal	5.55328	15.30625	K562	PUM2
chr15	37390400	37390529	-	5'-UTR,intron-Distal,intron-Proximal	5.50851	11.06447	HepG2	PCBP2
chr15	37390118	37390170	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.55354	12.35151	K562	AQR
chr15	37391405	37391477	-	5'-UTR,intron-Distal	3.09598	4.24221	K562	TARDBP
chr15	37390497	37390593	-	5'-UTR,intron-Distal,intron-Proximal	4.61480	10.57832	HepG2	PTBP1
chr15	37388691	37388699	-	5'-UTR,intron-Distal,intron-Proximal	6.08289	24.24524	K562	AQR
chr15	37390405	37390589	-	5'-UTR,intron-Distal,intron-Proximal	6.07479	30.27643	K562	PTBP1
chr15	37388633	37388697	-	5'-UTR,intron-Distal,intron-Proximal	3.62714	3.88924	K562	PRPF8
chr15	37385699	37385784	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.19963	6.39176	K562	AQR
chr15	37387768	37387824	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.39294	4.39669	K562	BUD13
chr15	37388621	37388691	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.77818	28.64455	K562	AQR
chr15	37390421	37390497	-	5'-UTR,intron-Distal,intron-Proximal	4.03675	6.90077	HepG2	PTBP1
chr15	37391585	37391657	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.70163	5.34337	K562	AQR
chr15	37391329	37391405	-	5'-UTR,intron-Distal	4.36515	9.61624	K562	TARDBP
chr15	37387804	37387858	-	5'-UTR,CDS,intron-Distal,intron-Proximal	5.15948	6.91748	K562	SF3B4
chr15	37391234	37391333	-	5'-UTR,intron-Distal	4.39096	6.26655	K562	EIF4G2
chr15	37391348	37391455	-	5'-UTR,intron-Distal	4.75102	7.19397	K562	EIF4G2
chr15	37187333	37187352	-	CDS,intron-Distal,intron-Proximal	5.08240	5.65342	K562	AQR
chr15	37244715	37244892	-	intron-Distal	5.03054	6.09580	K562	HNRNPL
chr15	37319850	37319978	-	intron-Distal	4.00074	3.91018	K562	KHDRBS1
chr15	37390045	37390118	-	intron-Distal,intron-Proximal	3.50698	13.83627	K562	AQR
chr15	37326290	37326332	-	intron-Distal	3.62889	9.96429	K562	PTBP1
chr15	37371362	37371464	-	intron-Distal	4.35056	5.02888	K562	KHSRP
chr15	37326177	37326254	-	intron-Distal	4.33334	9.54872	HepG2	PTBP1
chr15	37307622	37307686	-	intron-Distal	4.82214	5.79092	K562	TARDBP
chr15	37274474	37274577	-	intron-Distal	3.62496	6.16263	K562	SAFB2
chr15	37385592	37385645	-	intron-Distal	4.66935	3.42734	K562	PTBP1
chr15	37390031	37390121	-	intron-Distal,intron-Proximal	3.99043	3.22972	K562	TARDBP
chr15	37389994	37390112	-	intron-Distal,intron-Proximal	3.10091	5.75838	K562	PRPF8
chr15	37277830	37277921	-	intron-Distal	4.11172	4.37667	K562	SAFB2
chr15	37294374	37294461	-	intron-Distal	4.34200	5.20871	K562	SAFB2
chr15	37390865	37390924	-	intron-Distal	3.77859	3.05187	HepG2	QKI
chr15	37388444	37388489	-	intron-Distal,intron-Proximal	4.25459	8.79285	K562	AQR
chr15	37390883	37390929	-	intron-Distal	4.26157	6.59655	K562	PTBP1
chr15	37390829	37390916	-	intron-Distal,intron-Proximal	4.36336	4.96496	K562	NONO
chr15	37310562	37310667	-	intron-Distal	3.72040	3.06411	K562	KHDRBS1
chr15	37187307	37187333	-	intron-Distal,intron-Proximal	4.20636	6.01372	K562	AQR
chr15	37219529	37219627	-	intron-Distal	4.51957	4.30178	K562	PTBP1
chr15	37326254	37326331	-	intron-Distal	5.19963	8.82480	HepG2	PTBP1
chr15	37326177	37326253	-	intron-Distal	4.51133	16.21411	K562	PTBP1
chr15	37274977	37275058	-	intron-Distal	3.85678	3.86679	K562	SAFB2
chr15	37242231	37242298	-	intron-Distal	3.85468	5.93532	K562	PTBP1
chr15	37326253	37326290	-	intron-Distal	4.58542	12.63672	K562	PTBP1
chr15	37390049	37390129	-	intron-Distal,intron-Proximal	4.11812	6.08151	K562	BUD13
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for MEIS2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for MEIS2 is not available on ENCORE database.
42 RBPs can affect the levels of MEIS2.

The Knockdown/knockout RNA-Seq assay for MEIS2 is not available on ENCORE database.

42 RBPs can affect the gene expression of MEIS2 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
MEIS2	ENSG00000134138.15	336.56640	261.26450	0.36530	2.06700	1.52670	HepG2	ACO1
MEIS2	ENSG00000134138.15	231.43050	358.34680	-0.63080	4.94700	4.07300	HepG2	AUH
MEIS2	ENSG00000134138.15	335.38440	228.74060	0.55200	2.77780	2.00400	HepG2	CIRBP
MEIS2	ENSG00000134138.15	283.90250	165.76040	0.77620	3.33090	2.48490	HepG2	CNOT7
MEIS2	ENSG00000134138.15	161.85240	329.53020	-1.02570	7.35130	6.27230	HepG2	CPSF6
MEIS2	ENSG00000134138.15	672.32020	374.20400	0.84520	4.74690	3.47700	HepG2	DDX59
MEIS2	ENSG00000134138.15	156.94770	214.85200	-0.45310	1.96160	1.35880	HepG2	DNAJC21
MEIS2	ENSG00000134138.15	392.83500	285.41220	0.46080	2.34680	1.59430	HepG2	EIF4G2
MEIS2	ENSG00000134138.15	268.03460	165.82400	0.69270	3.75340	2.84640	HepG2	FUBP3
MEIS2	ENSG00000134138.15	350.61110	252.72360	0.47220	2.22990	1.43530	HepG2	G3BP2
MEIS2	ENSG00000134138.15	138.74040	216.91030	-0.64470	2.74340	2.09940	HepG2	HNRNPA1
MEIS2	ENSG00000134138.15	148.24650	242.02530	-0.70720	3.24790	2.52250	HepG2	IGF2BP2
MEIS2	ENSG00000134138.15	381.49060	264.25260	0.52960	2.71010	2.08300	HepG2	NCBP2
MEIS2	ENSG00000134138.15	411.45650	263.11300	0.64500	3.28980	1.72120	HepG2	NKRF
MEIS2	ENSG00000134138.15	353.87100	197.16050	0.84380	3.56690	2.31610	HepG2	NONO
MEIS2	ENSG00000134138.15	161.40320	237.24030	-0.55570	2.90610	2.04050	HepG2	PARN
MEIS2	ENSG00000134138.15	356.94400	270.56290	0.39960	2.39350	1.66810	HepG2	PRPF4
MEIS2	ENSG00000134138.15	206.36150	303.24440	-0.55530	3.16620	2.44870	HepG2	PUM2
MEIS2	ENSG00000134138.15	445.49690	266.11940	0.74320	6.86960	5.97420	HepG2	PUS1
MEIS2	ENSG00000134138.15	429.75090	263.14410	0.70750	5.88310	5.02040	HepG2	QKI
MEIS2	ENSG00000134138.15	490.35690	259.83170	0.91620	4.86880	3.94890	HepG2	RAVER1
MEIS2	ENSG00000134138.15	619.25840	412.55020	0.58590	5.81300	4.62730	HepG2	RBM15
MEIS2	ENSG00000134138.15	378.53920	252.96890	0.58140	4.22370	3.51780	HepG2	SF3B4
MEIS2	ENSG00000134138.15	353.96710	274.09270	0.36890	2.07300	1.44980	HepG2	SLBP
MEIS2	ENSG00000134138.15	136.33070	392.62670	-1.52600	11.40170	9.82890	HepG2	SNRNP70
MEIS2	ENSG00000134138.15	222.23350	388.40510	-0.80550	7.56960	6.85290	HepG2	SRFBP1
MEIS2	ENSG00000134138.15	295.83820	214.83490	0.46150	2.79290	2.23950	HepG2	SRSF9
MEIS2	ENSG00000134138.15	309.50740	237.37840	0.38270	1.99810	1.50880	HepG2	TAF15
MEIS2	ENSG00000134138.15	396.96880	282.71240	0.48960	2.54430	1.93960	HepG2	U2AF1
MEIS2	ENSG00000134138.15	99.89490	195.69890	-0.97020	3.78030	2.59140	HepG2	UPF2
MEIS2	ENSG00000134138.15	723.10800	918.63400	-0.34530	3.40960	2.79200	K562	AGGF1
MEIS2	ENSG00000134138.15	460.74880	618.19840	-0.42410	3.81200	2.67440	K562	BCLAF1
MEIS2	ENSG00000134138.15	516.80940	891.06410	-0.78590	10.53210	8.98720	K562	CPSF6
MEIS2	ENSG00000134138.15	350.36070	468.99560	-0.42070	2.42450	1.44350	K562	CSTF2
MEIS2	ENSG00000134138.15	810.68060	558.69380	0.53700	3.80750	2.57440	K562	EIF3D
MEIS2	ENSG00000134138.15	1508.04320	1294.84540	0.21980	2.15520	1.32030	K562	EIF4G2
MEIS2	ENSG00000134138.15	680.79140	850.74600	-0.32150	2.05970	1.37090	K562	GPKOW
MEIS2	ENSG00000134138.15	833.46470	1084.01630	-0.37920	3.00210	2.21610	K562	GRSF1
MEIS2	ENSG00000134138.15	962.41500	1196.87930	-0.31450	2.18740	1.47800	K562	HSPD1
MEIS2	ENSG00000134138.15	415.80750	651.42620	-0.64770	4.57300	3.11810	K562	IGF2BP2
MEIS2	ENSG00000134138.15	808.25770	1008.90780	-0.31990	3.46170	2.63640	K562	NSUN2
MEIS2	ENSG00000134138.15	777.56240	948.06460	-0.28600	1.92520	1.45670	K562	PUS1
MEIS2	ENSG00000134138.15	461.87210	652.40230	-0.49830	2.59380	1.90660	K562	SRSF1
MEIS2	ENSG00000134138.15	886.04770	674.01390	0.39450	2.22780	1.48980	K562	SYNCRIP
MEIS2	ENSG00000134138.15	354.19910	472.43700	-0.41560	2.09960	1.40080	K562	U2AF2
MEIS2	ENSG00000134138.15	743.34320	915.36890	-0.30030	2.16350	1.39090	K562	WDR3
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for MEIS2 is not available on ENCORE database.

6 RBPs can affect the splicing of MEIS2 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	MEIS2	ENSG00000134138.15	chr15	-	37186917	37187013			37183610	37184660	37187351	37187441	-0.41200	0.00129	0.01752	excluded	HepG2	U2AF2
SE	MEIS2	ENSG00000134138.15	chr15	-	37242524	37242601			37188828	37188887	37329014	37329160	-0.14000	0.00157	0.04793	excluded	K562	UTP18
SE	MEIS2	ENSG00000134138.15	chr15	-	37186917	37187013			37183610	37184660	37187351	37187441	-0.23300	0.00043	0.08046	excluded	K562	SAFB
SE	MEIS2	ENSG00000134138.15	chr15	-	37186917	37187013			37183610	37184660	37187351	37187441	0.33400	0.00000	0.00019	included	K562	HNRNPC
MXE	MEIS2	ENSG00000134138.15	chr15	-	37242524	37242601	37329014	37329160	37188828	37188887	37375971	37376086	0.25000	0.00582	0.06100	1included	K562	DROSHA
MXE	MEIS2	ENSG00000134138.15	chr15	-	37242524	37242601	37329014	37329160	37188828	37188887	37375971	37376086	0.28700	0.00251	0.04131	1included	K562	HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

MEIS2

General Information

Functions

Localization

Domains (AlphaFold: MEIS2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for MEIS2 is not avaliable on ENCORE database.

15 proteins are bound to MEIS2 RNA:

eCLIP assay for MEIS2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for MEIS2 is not available on ENCORE database.

42 RBPs can affect the gene expression of MEIS2 :

The Knockdown/knockout RNA-Seq assay for MEIS2 is not available on ENCORE database.

6 RBPs can affect the splicing of MEIS2 :

The Knockdown/knockout RNA-Seq assay for MEIS2 is not avaliable on ENCORE database.