KLHL20

General Information

Gene Name       : KLHL20
Gene ID             : ENSG00000076321.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: KLHL20)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878KLHL20ENSG00000076321.108.258.198.22ENCSR000AEF
HepG2KLHL20ENSG00000076321.107.149.678.40ENCSR985KAT
K562KLHL20ENSG00000076321.1014.3415.6314.98ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for KLHL20 is not avaliable on ENCORE database.



Proteins bound to RNA
  • KLHL20 RNA is bound by 11 proteins.  







eCLIP assay for KLHL20 is not avaliable on ENCORE database.





11 proteins are bound to KLHL20 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1173754360173754400+3'-UTR,CDS6.9402812.89621K562PUM2
chr1173755194173755283+3'-UTR4.525304.55095K562YBX3
chr1173754400173754458+3'-UTR5.6145429.96866K562PUM2
chr1173684215173684293+5'-UTR,intron-Proximal3.992114.89208K562AQR
chr1173684131173684252+5'-UTR,intron-Proximal4.474488.35706K562UCHL5
chr1173721022173721062+CDS,intron-Proximal6.4097324.02783K562LIN28B
chr1173722350173722401+CDS,intron-Proximal5.2410922.08597K562LIN28B
chr1173725107173725204+CDS,intron-Proximal3.745134.83899HepG2PRPF8
chr1173702836173702888+CDS,intron-Distal,intron-Proximal4.166684.23351K562BUD13
chr1173714766173714886+intron-Distal4.185104.58794K562KHSRP
chr1173716396173716492+intron-Distal4.246654.76003K562KHSRP
chr1173703425173703481+intron-Distal,intron-Proximal5.027314.86944K562AQR
chr1173716573173716631+intron-Distal3.249744.13575K562KHSRP
chr1173722502173722631+intron-Distal,intron-Proximal3.700263.06676K562U2AF2
chr1173712821173712933+intron-Distal3.696293.25538K562KHSRP
chr1173716492173716573+intron-Distal3.593275.78005K562KHSRP
chr1173693620173693699+intron-Distal3.971553.92684K562KHSRP
chr1173716631173716713+intron-Distal4.531856.73684K562KHSRP
chr1173722515173722626+intron-Distal,intron-Proximal3.774934.36528HepG2U2AF2
chr1173686233173686340+intron-Distal4.102044.93238K562QKI
chr1173686581173686691+intron-Distal3.843813.14791K562HNRNPL
chr1173716278173716396+intron-Distal4.401584.96658K562KHSRP
chr1173694525173694625+intron-Distal3.471834.22563K562UCHL5
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for KLHL20 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for KLHL20 is not available on ENCORE database.

  • 43 RBPs can affect the levels of KLHL20.  








The Knockdown/knockout RNA-Seq assay for KLHL20 is not available on ENCORE database.





43 RBPs can affect the gene expression of KLHL20 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
KLHL20ENSG00000076321.6579.54530409.151700.502202.667002.14470HepG2AKAP1
KLHL20ENSG00000076321.6408.65740282.634900.531903.326302.49070HepG2CALR
KLHL20ENSG00000076321.6433.55460321.638100.430702.161401.47240HepG2CIRBP
KLHL20ENSG00000076321.6373.88720252.951800.563602.278201.58890HepG2CNOT7
KLHL20ENSG00000076321.6310.22580217.215800.514102.573801.91600HepG2DDX21
KLHL20ENSG00000076321.6661.14750486.942300.441103.918403.22390HepG2ETF1
KLHL20ENSG00000076321.6580.73820345.369000.749605.230404.19990HepG2FIP1L1
KLHL20ENSG00000076321.6365.49560243.879600.583603.291702.59530HepG2HNRNPA1
KLHL20ENSG00000076321.6343.14090269.495700.348401.909601.39710HepG2HNRNPU
KLHL20ENSG00000076321.6265.03740360.99910-0.445801.962401.40570HepG2MAGOH
KLHL20ENSG00000076321.6434.79780279.581300.637004.581903.56130HepG2MSI2
KLHL20ENSG00000076321.6209.37840302.04300-0.528602.352901.66080HepG2NSUN2
KLHL20ENSG00000076321.6388.04770270.924500.518202.243301.30600HepG2PCBP2
KLHL20ENSG00000076321.6353.76950276.190700.357002.042601.37030HepG2PRPF4
KLHL20ENSG00000076321.6304.56180203.343300.582702.711001.91040HepG2PRPF8
KLHL20ENSG00000076321.6413.38800325.108700.346501.860501.39450HepG2PTBP1
KLHL20ENSG00000076321.6348.34400271.106000.361602.066401.51560HepG2PUS1
KLHL20ENSG00000076321.6467.02240352.158600.407202.044501.49590HepG2QKI
KLHL20ENSG00000076321.6450.85270350.553400.362902.083701.32620HepG2RBM15
KLHL20ENSG00000076321.6625.86220406.996400.620706.469205.75710HepG2RBM22
KLHL20ENSG00000076321.6425.86040319.584700.414102.194401.58790HepG2RBM25
KLHL20ENSG00000076321.6371.28610256.795000.531802.228201.37890HepG2RPS10
KLHL20ENSG00000076321.6557.58010353.330900.658106.507205.85590HepG2SRSF1
KLHL20ENSG00000076321.6464.77950311.793800.575904.886504.09290HepG2SRSF5
KLHL20ENSG00000076321.6548.78660399.130500.459304.143103.54270HepG2SSB
KLHL20ENSG00000076321.6507.89690295.476200.781406.118905.20150HepG2U2AF1
KLHL20ENSG00000076321.61057.25230792.597600.415603.103002.48840K562AQR
KLHL20ENSG00000076321.6825.87470532.284900.633605.538304.29320K562BOP1
KLHL20ENSG00000076321.6813.98760565.948200.524204.838103.80520K562CPSF6
KLHL20ENSG00000076321.61668.284801279.052300.383204.450503.20360K562CELF1
KLHL20ENSG00000076321.61013.25520847.952000.256802.271201.67210K562DDX47
KLHL20ENSG00000076321.6626.83040472.923000.406402.264901.33960K562EIF3D
KLHL20ENSG00000076321.6883.62820575.884100.617605.843104.58990K562FMR1
KLHL20ENSG00000076321.6644.40510488.133300.400602.254401.43410K562FTO
KLHL20ENSG00000076321.6675.13700514.580600.391701.907601.33310K562G3BP2
KLHL20ENSG00000076321.6780.06800540.322600.529704.483903.47820K562GPKOW
KLHL20ENSG00000076321.6567.37060808.95180-0.511804.362003.41750K562GRSF1
KLHL20ENSG00000076321.6451.27650612.95690-0.441802.343901.42160K562IGF2BP2
KLHL20ENSG00000076321.6453.29980644.39350-0.507504.224103.18160K562MAGOH
KLHL20ENSG00000076321.6706.53400527.423100.421702.762601.88660K562METAP2
KLHL20ENSG00000076321.6570.73160429.752700.409202.390601.69170K562PRPF8
KLHL20ENSG00000076321.6391.95520626.05370-0.675607.138206.10980K562PTBP1
KLHL20ENSG00000076321.6605.06630784.93550-0.375502.252301.75250K562PUS1
KLHL20ENSG00000076321.6607.95100764.80760-0.331102.418701.85790K562RBM15
KLHL20ENSG00000076321.6387.72340631.82040-0.704506.259504.53400K562NELFE
KLHL20ENSG00000076321.6685.89360513.934000.416302.347401.45740K562SF3B1
KLHL20ENSG00000076321.6640.55610515.317500.313802.110201.40970K562U2AF2
KLHL20ENSG00000076321.6862.19520718.723200.262502.027101.40600K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for KLHL20 is not available on ENCORE database.





6 RBPs can affect the splicing of KLHL20 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEKLHL20ENSG00000076321.6chr1+173743443173743577173735284173735428173744772173744981-0.220000.002770.04709excludedK562SF3B4
SEKLHL20ENSG00000076321.6chr1+1737225441737226931737223511737224461737250611737251770.064000.011200.08886includedK562AQR
SEKLHL20ENSG00000076321.6chr1+173744772173744981173735284173735428173751261173751368-0.334000.000000.00002excludedK562AQR
SEKLHL20ENSG00000076321.6chr1+173725061173725177173722351173722446173726114173726224-0.137000.000750.00960excludedK562AQR
SEKLHL20ENSG00000076321.6chr1+1737225441737226931737223511737224461737250611737251770.212000.000150.00346includedK562PUS1
SEKLHL20ENSG00000076321.6chr1+173743443173743577173735284173735428173744772173744981-0.177000.000040.00116excludedK562PUS1
SEKLHL20ENSG00000076321.6chr1+1736846611736847931736840791736842171736851411736852050.460000.000710.08394includedK562LARP4
SEKLHL20ENSG00000076321.6chr1+1737225441737226931737223511737224461737250611737251770.104000.000560.04436includedK562HNRNPUL1
SEKLHL20ENSG00000076321.6chr1+1737225441737226931737223511737224461737250611737251770.206000.000510.01139includedK562U2AF2
A3SSKLHL20ENSG00000076321.6chr1+1737512261737513681737512611737513681737447721737449810.096000.000880.00621longerK562AQR
A3SSKLHL20ENSG00000076321.6chr1+1737250281737251771737250611737251771737223511737224460.112000.001810.01179longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for KLHL20 is not avaliable on ENCORE database.