ITGB4

General Information

Gene Name       : ITGB4
Gene ID             : ENSG00000132470.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ITGB4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ITGB4ENSG00000132470.130.000.070.04ENCSR000AEF
HepG2ITGB4ENSG00000132470.1318.652.8910.77ENCSR985KAT
K562ITGB4ENSG00000132470.130.620.390.51ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ITGB4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ITGB4 RNA is bound by 1 proteins.  







eCLIP assay for ITGB4 is not avaliable on ENCORE database.





1 proteins are bound to ITGB4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr177375060573750662+CDS,intron-Distal,intron-Proximal6.033506.39134HepG2SF3A3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ITGB4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ITGB4 is not available on ENCORE database.

  • 82 RBPs can affect the levels of ITGB4.  








The Knockdown/knockout RNA-Seq assay for ITGB4 is not available on ENCORE database.





82 RBPs can affect the gene expression of ITGB4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ITGB4ENSG00000132470.9127.70700256.43500-1.005808.419407.47560HepG2ACO1
ITGB4ENSG00000132470.9383.23000209.938400.868106.054104.91500HepG2ASCC1
ITGB4ENSG00000132470.9235.42880110.475101.091504.288103.19100HepG2BCLAF1
ITGB4ENSG00000132470.9136.76890290.39490-1.086304.598903.63430HepG2CALR
ITGB4ENSG00000132470.9397.98430140.028001.506907.612106.64410HepG2CELF1
ITGB4ENSG00000132470.959.79000142.82110-1.256202.120701.33130HepG2DDX24
ITGB4ENSG00000132470.91357.56810125.076203.4400038.1962035.86610HepG2DDX55
ITGB4ENSG00000132470.9564.31210208.863801.433808.103507.09890HepG2DDX6
ITGB4ENSG00000132470.9154.94850245.32660-0.662903.791503.02250HepG2DKC1
ITGB4ENSG00000132470.9229.4039097.377501.236109.870108.60460HepG2DNAJC21
ITGB4ENSG00000132470.9242.3287096.517001.3280013.0585011.74960HepG2DNAJC2
ITGB4ENSG00000132470.9485.70480200.693901.2750013.0517011.82870HepG2EIF2S1
ITGB4ENSG00000132470.9148.35090237.36720-0.678103.209001.32930HepG2EIF3H
ITGB4ENSG00000132470.9142.45890221.74580-0.638402.687102.05740HepG2EIF4A3
ITGB4ENSG00000132470.9231.26710142.290200.700603.508102.60000HepG2EIF4G2
ITGB4ENSG00000132470.9590.65840392.339100.590105.605504.79930HepG2ETF1
ITGB4ENSG00000132470.9343.15660223.866900.616103.281602.53110HepG2FXR1
ITGB4ENSG00000132470.9265.25110105.182701.334408.822306.98360HepG2GNB2L1
ITGB4ENSG00000132470.9699.36820516.662300.436702.497601.88630HepG2GPKOW
ITGB4ENSG00000132470.9211.27870138.368800.610502.964502.00250HepG2HNRNPA2B1
ITGB4ENSG00000132470.9288.53600137.140901.0730010.482709.24890HepG2HNRNPL
ITGB4ENSG00000132470.9306.17950493.06130-0.687404.841204.03200HepG2HNRNPLL
ITGB4ENSG00000132470.9190.87780108.629000.813104.593703.82920HepG2HNRNPU
ITGB4ENSG00000132470.9120.11300210.99420-0.812803.888803.10150HepG2IGF2BP2
ITGB4ENSG00000132470.9191.42940110.960900.786704.681403.74950HepG2ILF2
ITGB4ENSG00000132470.9207.5907093.377301.152504.913303.26350HepG2KHDRBS1
ITGB4ENSG00000132470.9172.05060103.108200.738602.586601.48860HepG2LARP7
ITGB4ENSG00000132470.9143.60780223.94560-0.641002.201301.61340HepG2MAGOH
ITGB4ENSG00000132470.9130.27390225.17710-0.789503.231802.55420HepG2MATR3
ITGB4ENSG00000132470.9258.79550380.44260-0.555903.368402.47900HepG2MSI2
ITGB4ENSG00000132470.9418.93820230.463500.862106.061905.14120HepG2NCBP2
ITGB4ENSG00000132470.9229.00770149.290300.617203.276502.44880HepG2NOL12
ITGB4ENSG00000132470.9303.95530103.425001.555204.301802.52240HepG2NOLC1
ITGB4ENSG00000132470.9308.10060114.964701.422104.272202.89400HepG2NONO
ITGB4ENSG00000132470.9406.6656089.445402.1847010.888409.09960HepG2PABPC1
ITGB4ENSG00000132470.9162.39900107.524300.594802.398301.60560HepG2PARN
ITGB4ENSG00000132470.9288.4520096.888401.5738017.7576016.00310HepG2PPIL4
ITGB4ENSG00000132470.9301.41450225.581000.418002.004601.52550HepG2PTBP1
ITGB4ENSG00000132470.9331.71380142.513401.2187011.3328010.23720HepG2PUF60
ITGB4ENSG00000132470.9239.84760151.287400.664704.250503.54890HepG2PUM1
ITGB4ENSG00000132470.9276.92330151.174900.873206.045105.06610HepG2PUM2
ITGB4ENSG00000132470.9196.68220261.18880-0.409202.034501.48750HepG2PUS1
ITGB4ENSG00000132470.9142.12880244.30230-0.781504.435903.67070HepG2QKI
ITGB4ENSG00000132470.9141.72870327.91920-1.2102011.5299010.62580HepG2RBM22
ITGB4ENSG00000132470.9112.67060226.09660-1.004806.175105.21170HepG2RPLP0
ITGB4ENSG00000132470.9184.6805096.739000.932805.525204.66700HepG2SAFB2
ITGB4ENSG00000132470.9170.05420383.58040-1.173506.209405.17520HepG2SF3A3
ITGB4ENSG00000132470.9228.36880136.654600.740704.667103.79290HepG2SLBP
ITGB4ENSG00000132470.9292.24850112.814201.3731014.9139013.60290HepG2SMN1
ITGB4ENSG00000132470.9423.36680182.150601.216704.195802.50530HepG2SNRNP200
ITGB4ENSG00000132470.9212.52920543.01790-1.3533011.026709.48050HepG2SNRNP70
ITGB4ENSG00000132470.972.20530245.13790-1.7634013.9964013.10820HepG2SRSF1
ITGB4ENSG00000132470.9304.20750140.715001.112209.435808.37310HepG2SRSF5
ITGB4ENSG00000132470.9183.38130321.55430-0.810206.942406.20050HepG2SSB
ITGB4ENSG00000132470.9331.58560160.028401.0510010.932809.83460HepG2SUCLG1
ITGB4ENSG00000132470.9302.95900124.476601.283103.659502.89740HepG2SUPV3L1
ITGB4ENSG00000132470.967.34740220.34660-1.7101014.2848013.15710HepG2TAF15
ITGB4ENSG00000132470.9337.48240106.496801.6639023.0224021.59580HepG2TRIM56
ITGB4ENSG00000132470.9270.66190402.14490-0.571203.278902.60030HepG2U2AF1
ITGB4ENSG00000132470.9461.03390211.886701.121503.251802.18100HepG2U2AF2
ITGB4ENSG00000132470.9329.93990147.381101.162604.758903.64520HepG2UBE2L3
ITGB4ENSG00000132470.9124.99890328.42610-1.393707.763706.84160HepG2UTP3
ITGB4ENSG00000132470.9200.67560290.80490-0.535203.298902.57590HepG2ZC3H8
ITGB4ENSG00000132470.9237.09070374.12890-0.658102.853402.30070HepG2ZNF622
ITGB4ENSG00000132470.963.5239027.543101.205502.684101.48580K562ABCF1
ITGB4ENSG00000132470.994.8702053.779000.818802.479701.93720K562AGGF1
ITGB4ENSG00000132470.981.2293017.038102.253102.641802.06500K562AQR
ITGB4ENSG00000132470.924.609003.367902.869202.842201.50870K562BCCIP
ITGB4ENSG00000132470.932.764703.253503.332005.578904.20010K562BCLAF1
ITGB4ENSG00000132470.947.8133013.702201.802904.480103.07430K562CCAR1
ITGB4ENSG00000132470.9138.1922064.262801.104505.466703.77340K562CCDC124
ITGB4ENSG00000132470.927.977902.468303.502604.881903.41950K562CSTF2
ITGB4ENSG00000132470.9118.2738063.097600.906403.560901.88980K562DDX19B
ITGB4ENSG00000132470.944.0427019.796301.153602.081201.34200K562FIP1L1
ITGB4ENSG00000132470.947.5472014.989501.665303.069202.27550K562GRSF1
ITGB4ENSG00000132470.935.7956014.844701.269701.801001.30680K562HNRNPC
ITGB4ENSG00000132470.925.393505.917902.101202.617501.62900K562IGF2BP2
ITGB4ENSG00000132470.971.3318033.647501.083902.199501.47500K562MTPAP
ITGB4ENSG00000132470.930.946407.950701.960502.648401.39580K562NONO
ITGB4ENSG00000132470.962.0461022.519501.462102.780401.78740K562PABPN1
ITGB4ENSG00000132470.930.124907.954401.921002.361901.61010K562RPS19
ITGB4ENSG00000132470.943.8487015.077901.540003.103401.75900K562SLBP
ITGB4ENSG00000132470.923.225605.601402.051802.738501.69680K562SRSF5
ITGB4ENSG00000132470.923.857006.010801.988702.631001.93930K562TARDBP
ITGB4ENSG00000132470.929.045305.797102.324803.596602.64430K562TIA1
ITGB4ENSG00000132470.937.7886012.802101.561502.574501.67530K562TIAL1
ITGB4ENSG00000132470.951.8285013.604301.929604.480103.21180K562TRIM56
ITGB4ENSG00000132470.969.0652033.930601.025302.557501.71280K562WDR3
ITGB4ENSG00000132470.953.2166019.181901.472003.740002.70910K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ITGB4 is not available on ENCORE database.





3 RBPs can affect the splicing of ITGB4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEITGB4ENSG00000132470.9chr17+737517817375193173750656737508967375250973752698-0.441000.000000.00000excludedHepG2U2AF1
SEITGB4ENSG00000132470.9chr17+737517817375193173750656737508967375250973752698-0.256000.001910.07569excludedHepG2SF3B4
SEITGB4ENSG00000132470.9chr17+737498457375005573748526737486587375065673750896-0.468000.000650.09833excludedHepG2DDX55

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ITGB4 is not avaliable on ENCORE database.