CWC15

General Information

Gene Name : CWC15
Gene ID : ENSG00000150316.11
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: CWC15)

Not Available

Antibody Validation

View validation images for all CWC15 antibodies

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	CWC15	ENSG00000150316.11	67.68	53.41	60.55	ENCSR000AEF
HepG2	CWC15	ENSG00000150316.11	30.89	48.64	39.77	ENCSR985KAT
K562	CWC15	ENSG00000150316.11	58.06	65.11	61.59	ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	CWC15-BGKcLV28-K562	ENCSR825RYR	CWC15	K562	Released		ENCSR220DTX	CRISPR	KD% = 51.7,53.4

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
CWC15	ENCAB616CRG	A304-900A	1			Released, ENCODE4		BGKcLV28-53, Released, ENCODE4
CWC15	ENCAB952MZJ	A304-901A	1			Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
CWC15	K562	CRISPR	ENCSR825RYR	ENCSR220DTX	CWC15-BGKcLV28-53,CWC15-BGKcLV28-54	NT-BGKcLV28-1,NT-BGKcLV28-2	51.7,53.4	Released	ENCODE4
CWC15	HepG2	CRISPR			BGHcLV29-53,BGHcLV29-54	BGHcLV29-1,BGHcLV29-2	0,0	NotSatisfied	ENCODE4
CWC15	HepG2	CRISPR			BGHcLV34-19,BGHcLV34-20	BGHcLV34-1,BGHcLV34-2	0.0,0.0	NotSatisfied	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
CWC15	Product_ID: A304-900A Lot_ID: 1 Source: Bethyl Labs Target Name: CWC15-human
CWC15	Product_ID: A304-901A Lot_ID: 1 Source: Bethyl Labs Target Name: CWC15-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for CWC15 is not avaliable on ENCORE database.

Proteins bound to RNA

CWC15 RNA is bound by 17 proteins.

eCLIP assay for CWC15 is not avaliable on ENCORE database.

17 proteins are bound to CWC15 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr11	94706659	94706709	-	5'-UTR,intron-Distal,intron-Proximal	4.05601	13.57683	K562	ZNF622
chr11	94706660	94706729	-	5'-UTR,intron-Distal,intron-Proximal	3.42609	4.32211	K562	DDX3X
chr11	94706660	94706701	-	5'-UTR,intron-Distal	3.40778	5.65349	K562	UCHL5
chr11	94705307	94705358	-	5'-UTR,CDS,intron-Distal,intron-Proximal	3.12168	5.77418	K562	UCHL5
chr11	94703152	94703181	-	CDS,intron-Distal,intron-Proximal	4.55206	9.77102	K562	UCHL5
chr11	94703151	94703159	-	CDS,intron-Distal,intron-Proximal	3.18983	5.48645	K562	GRWD1
chr11	94704478	94704574	-	CDS,intron-Distal,intron-Proximal	3.09169	3.22124	K562	EFTUD2
chr11	94703241	94703261	-	CDS,intron-Distal,intron-Proximal	3.91820	8.70187	K562	ZNF622
chr11	94699552	94699626	-	CDS,intron-Distal,intron-Proximal	3.88791	7.09030	K562	SF3B4
chr11	94703157	94703238	-	CDS,intron-Distal	4.43103	4.69071	HepG2	GRWD1
chr11	94705325	94705349	-	CDS,intron-Distal	3.22932	5.94292	K562	ZNF622
chr11	94703152	94703259	-	CDS,intron-Distal,intron-Proximal	3.17805	9.95292	HepG2	BCLAF1
chr11	94696603	94696675	-	CDS,intron-Distal	3.60120	5.36496	K562	ZNF800
chr11	94704501	94704552	-	CDS,intron-Distal,intron-Proximal	5.28345	7.81477	K562	SF3B4
chr11	94699492	94699534	-	CDS,intron-Distal,intron-Proximal	4.29107	3.89826	HepG2	BCLAF1
chr11	94704140	94704225	-	CDS,intron-Distal,intron-Proximal	3.04319	9.24685	K562	ZNF622
chr11	94696637	94696666	-	CDS,intron-Distal	3.03855	4.83253	K562	GRWD1
chr11	94703235	94703261	-	CDS,intron-Distal,intron-Proximal	3.74207	3.26602	K562	PUM1
chr11	94696575	94696617	-	CDS,intron-Distal	3.88506	10.31435	K562	PUM2
chr11	94696571	94696613	-	CDS,intron-Distal	3.10288	3.94979	HepG2	BCLAF1
chr11	94699534	94699578	-	CDS,intron-Distal,intron-Proximal	3.91291	8.48086	K562	UCHL5
chr11	94703148	94703261	-	CDS,intron-Distal,intron-Proximal	3.46616	4.17990	K562	CPSF6
chr11	94703174	94703241	-	CDS,intron-Distal	3.09734	12.62180	K562	ZNF622
chr11	94705219	94705279	-	CDS,intron-Distal	3.20210	7.87286	K562	ZNF622
chr11	94704531	94704651	-	CDS,intron-Distal,intron-Proximal	3.38868	16.15040	K562	ZNF622
chr11	94704143	94704230	-	CDS,intron-Distal,intron-Proximal	3.98056	7.22820	K562	YBX3
chr11	94703181	94703260	-	CDS,intron-Distal	3.36328	13.21784	K562	UCHL5
chr11	94703152	94703174	-	CDS,intron-Distal,intron-Proximal	4.34584	8.16704	K562	ZNF622
chr11	94704491	94704548	-	CDS,intron-Distal,intron-Proximal	4.49211	8.29266	K562	AQR
chr11	94703262	94703324	-	intron-Distal,intron-Proximal	3.26403	4.13620	K562	KHSRP
chr11	94699368	94699410	-	intron-Distal,intron-Proximal	3.56223	6.16312	K562	AQR
chr11	94706552	94706613	-	intron-Distal	4.61607	8.52787	K562	AQR
chr11	94699357	94699415	-	intron-Distal,intron-Proximal	4.40739	3.96990	K562	BUD13
chr11	94703324	94703353	-	intron-Distal,intron-Proximal	4.30907	5.41654	K562	KHSRP
chr11	94704389	94704486	-	intron-Distal,intron-Proximal	3.29343	3.40058	K562	PRPF8
chr11	94699351	94699412	-	intron-Distal,intron-Proximal	4.03635	5.84589	K562	EFTUD2
chr11	94706613	94706661	-	intron-Distal	3.64986	5.35619	K562	AQR
chr11	94704385	94704507	-	intron-Distal,intron-Proximal	3.78739	6.41553	K562	KHSRP
chr11	94705170	94705212	-	intron-Distal,intron-Proximal	4.74336	4.65563	K562	AQR
chr11	94699350	94699416	-	intron-Distal,intron-Proximal	3.14690	3.44195	K562	TARDBP
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for CWC15 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for CWC15 is not available on ENCORE database.
56 RBPs can affect the levels of CWC15.

The Knockdown/knockout RNA-Seq assay for CWC15 is not available on ENCORE database.

56 RBPs can affect the gene expression of CWC15 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CWC15	ENSG00000150316.7	587.14880	847.07320	-0.52880	3.21990	2.16370	HepG2	CCAR1
CWC15	ENSG00000150316.7	665.50100	807.37230	-0.27880	1.95140	1.39330	HepG2	CELF1
CWC15	ENSG00000150316.7	362.88690	777.31680	-1.09900	11.76110	10.59380	HepG2	DDX6
CWC15	ENSG00000150316.7	362.06950	508.98890	-0.49140	2.79420	1.86900	HepG2	EEF2
CWC15	ENSG00000150316.7	507.69270	747.36880	-0.55790	4.06940	3.35970	HepG2	EIF2S1
CWC15	ENSG00000150316.7	523.98740	804.10700	-0.61790	3.73400	2.94110	HepG2	EIF4B
CWC15	ENSG00000150316.7	327.83220	432.74720	-0.40060	2.15390	1.45360	HepG2	FUBP3
CWC15	ENSG00000150316.7	651.75490	833.21660	-0.35440	2.05500	1.45500	HepG2	FXR1
CWC15	ENSG00000150316.7	317.22640	773.01940	-1.28500	16.67340	15.10870	HepG2	G3BP1
CWC15	ENSG00000150316.7	593.84120	790.64350	-0.41300	4.17040	3.35580	HepG2	HNRNPL
CWC15	ENSG00000150316.7	557.01140	785.78890	-0.49640	3.41410	2.67180	HepG2	IGF2BP2
CWC15	ENSG00000150316.7	664.60410	894.20740	-0.42810	2.31130	1.55700	HepG2	LARP4
CWC15	ENSG00000150316.7	631.81610	857.96590	-0.44140	2.72910	2.10060	HepG2	NCBP2
CWC15	ENSG00000150316.7	513.03540	764.17710	-0.57480	4.32010	3.43110	HepG2	PABPC4
CWC15	ENSG00000150316.7	446.25480	740.59400	-0.73080	10.62070	9.55620	HepG2	PCBP1
CWC15	ENSG00000150316.7	489.28040	753.58400	-0.62310	7.57870	6.76290	HepG2	PTBP1
CWC15	ENSG00000150316.7	624.78380	872.26900	-0.48140	6.26970	5.45260	HepG2	PUM1
CWC15	ENSG00000150316.7	674.50390	816.14600	-0.27500	1.87630	1.34700	HepG2	QKI
CWC15	ENSG00000150316.7	587.94810	838.66510	-0.51240	5.80190	5.06410	HepG2	NELFE
CWC15	ENSG00000150316.7	617.60910	781.10540	-0.33880	2.89860	2.26890	HepG2	RECQL
CWC15	ENSG00000150316.7	940.92000	641.36870	0.55280	2.58960	1.93670	HepG2	SF3A3
CWC15	ENSG00000150316.7	635.36150	784.57480	-0.30430	2.44530	1.88470	HepG2	SF3B4
CWC15	ENSG00000150316.7	415.65530	505.10690	-0.28120	1.87430	1.32740	HepG2	SMN1
CWC15	ENSG00000150316.7	625.12190	811.31810	-0.37610	3.38100	2.70140	HepG2	SRSF5
CWC15	ENSG00000150316.7	503.77030	666.24240	-0.40330	3.88790	3.25610	HepG2	SRSF9
CWC15	ENSG00000150316.7	879.48330	711.65440	0.30540	2.73760	2.22690	HepG2	SSB
CWC15	ENSG00000150316.7	362.82230	476.89350	-0.39440	2.04340	1.40830	HepG2	TARDBP
CWC15	ENSG00000150316.7	330.03990	476.83290	-0.53080	4.78670	4.08620	HepG2	TRIM56
CWC15	ENSG00000150316.7	225.96200	497.56490	-1.13880	2.96370	1.93930	HepG2	U2AF2
CWC15	ENSG00000150316.7	445.87890	568.79670	-0.35130	2.74600	2.04890	HepG2	UPF1
CWC15	ENSG00000150316.7	398.12510	549.14980	-0.46400	3.90060	3.20790	HepG2	UTP3
CWC15	ENSG00000150316.7	685.86330	501.33160	0.45210	3.37900	2.58250	HepG2	XRN2
CWC15	ENSG00000150316.7	252.89680	583.78970	-1.20690	11.60870	8.86790	HepG2	ZRANB2
CWC15	ENSG00000150316.7	1436.24270	905.68010	0.66510	13.21200	12.07090	K562	AGGF1
CWC15	ENSG00000150316.7	1284.86980	995.15980	0.36850	2.97910	1.94830	K562	AKAP8
CWC15	ENSG00000150316.7	1447.11570	942.38990	0.61870	7.54410	6.41880	K562	AKAP8L
CWC15	ENSG00000150316.7	1880.92780	1416.10010	0.40940	4.12110	3.43290	K562	AQR
CWC15	ENSG00000150316.7	1273.63570	988.77270	0.36510	3.80760	2.72170	K562	ATP5C1
CWC15	ENSG00000150316.7	276.63380	386.99510	-0.48430	2.65770	1.63200	K562	CCAR1
CWC15	ENSG00000150316.7	1296.99470	1014.14950	0.35480	3.82660	2.77420	K562	DKC1
CWC15	ENSG00000150316.7	1201.69240	923.44920	0.37990	3.00700	2.12010	K562	FIP1L1
CWC15	ENSG00000150316.7	951.03630	688.86380	0.46520	5.33710	4.53490	K562	FXR1
CWC15	ENSG00000150316.7	1885.52520	1528.87470	0.30240	2.51480	1.79090	K562	GRSF1
CWC15	ENSG00000150316.7	558.25850	714.47250	-0.35590	2.31420	1.76160	K562	HNRNPC
CWC15	ENSG00000150316.7	1040.16260	759.56640	0.45350	3.16380	2.16280	K562	HNRNPM
CWC15	ENSG00000150316.7	1507.96500	1000.15060	0.59230	7.00050	5.54510	K562	KIF1C
CWC15	ENSG00000150316.7	843.91270	1042.40000	-0.30470	2.29480	1.46140	K562	MATR3
CWC15	ENSG00000150316.7	1422.03030	1120.41580	0.34380	2.83620	1.91290	K562	MBNL1
CWC15	ENSG00000150316.7	1372.25400	785.32690	0.80510	4.36240	3.17860	K562	NAA15
CWC15	ENSG00000150316.7	1274.93840	801.91720	0.66880	2.91010	1.88690	K562	PABPN1
CWC15	ENSG00000150316.7	1291.12260	1048.32100	0.30040	1.99590	1.30270	K562	PPIG
CWC15	ENSG00000150316.7	1119.16980	686.33430	0.70530	7.99330	6.71190	K562	PRPF8
CWC15	ENSG00000150316.7	2240.60420	1838.25460	0.28550	2.04320	1.34160	K562	PUF60
CWC15	ENSG00000150316.7	2134.36200	934.67270	1.19120	24.11020	22.51670	K562	PUS1
CWC15	ENSG00000150316.7	1506.05390	910.63100	0.72570	13.30580	11.99960	K562	RBM15
CWC15	ENSG00000150316.7	712.12900	948.55520	-0.41360	2.91270	1.48720	K562	RBM34
CWC15	ENSG00000150316.7	548.80140	783.43950	-0.51350	4.34890	2.97970	K562	SRSF4
CWC15	ENSG00000150316.7	714.80300	1006.84210	-0.49420	4.19430	3.31820	K562	TARDBP
CWC15	ENSG00000150316.7	728.35110	971.20000	-0.41510	3.68470	2.72180	K562	TIA1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for CWC15 is not available on ENCORE database.

7 RBPs can affect the splicing of CWC15 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	CWC15	ENSG00000150316.7	chr11	-	94704347	94704436	94703653	94704229	94704538	94704651	0.06700	0.00000	0.00000	included	HepG2	U2AF2
SE	CWC15	ENSG00000150316.7	chr11	-	94704347	94704436	94703653	94704229	94704538	94704651	0.05200	0.00000	0.00001	included	K562	U2AF2
A3SS	CWC15	ENSG00000150316.7	chr11	-	94703152	94703341	94703152	94703260	94704140	94704278	0.09400	0.00000	0.00000	longer	K562	AQR
A3SS	CWC15	ENSG00000150316.7	chr11	-	94696532	94696754	94696532	94696679	94699459	94699607	0.08100	0.00000	0.00000	longer	K562	AQR
A3SS	CWC15	ENSG00000150316.7	chr11	-	94705218	94705433	94705218	94705357	94706661	94706776	0.08900	0.00000	0.00000	longer	K562	AQR
RI	CWC15	ENSG00000150316.7	chr11	-	94704140	94704651	94704140	94704229	94704538	94704651	0.11500	0.00000	0.00000	included	K562	PUS1
RI	CWC15	ENSG00000150316.7	chr11	-	94704140	94704651	94704140	94704229	94704538	94704651	0.10600	0.00000	0.00000	included	HepG2	U2AF2
RI	CWC15	ENSG00000150316.7	chr11	-	94704140	94704651	94704140	94704229	94704538	94704651	0.05800	0.00000	0.00000	included	K562	AGGF1
RI	CWC15	ENSG00000150316.7	chr11	-	94704140	94704651	94704140	94704229	94704538	94704651	0.06200	0.00000	0.00000	included	K562	AKAP8L
RI	CWC15	ENSG00000150316.7	chr11	-	94704140	94704651	94704140	94704229	94704538	94704651	0.07700	0.00000	0.00001	included	HepG2	U2AF1
RI	CWC15	ENSG00000150316.7	chr11	-	94704140	94704651	94704140	94704229	94704538	94704651	0.06900	0.00035	0.01008	included	K562	U2AF1
RI	CWC15	ENSG00000150316.7	chr11	-	94704140	94704651	94704140	94704229	94704538	94704651	0.13500	0.00000	0.00000	included	K562	U2AF2
RI	CWC15	ENSG00000150316.7	chr11	-	94704140	94704651	94704140	94704229	94704538	94704651	0.06900	0.00000	0.00000	included	K562	UTP18

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

CWC15

General Information

Functions

Localization

Domains (AlphaFold: CWC15)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for CWC15 is not avaliable on ENCORE database.

17 proteins are bound to CWC15 RNA:

eCLIP assay for CWC15 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for CWC15 is not available on ENCORE database.

56 RBPs can affect the gene expression of CWC15 :

The Knockdown/knockout RNA-Seq assay for CWC15 is not available on ENCORE database.

7 RBPs can affect the splicing of CWC15 :

The Knockdown/knockout RNA-Seq assay for CWC15 is not avaliable on ENCORE database.