COG1

General Information

Gene Name       : COG1
Gene ID             : ENSG00000166685.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: COG1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878COG1ENSG00000166685.1116.3113.2414.77ENCSR000AEF
HepG2COG1ENSG00000166685.1129.3723.2426.30ENCSR985KAT
K562COG1ENSG00000166685.1120.4513.1716.81ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for COG1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • COG1 RNA is bound by 7 proteins.  







eCLIP assay for COG1 is not avaliable on ENCORE database.





7 proteins are bound to COG1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr177119286171192933+3'-UTR,CDS,intron-Proximal5.562939.06713HepG2PRPF8
chr177120296271203032+5'-UTR,intron-Proximal3.236704.76426K562PRPF8
chr177120330171203393+5'-UTR,CDS,intron-Proximal4.519814.23351K562BUD13
chr177120330271203346+5'-UTR,CDS,intron-Proximal3.831154.41130K562AQR
chr177120338671203448+5'-UTR,CDS,intron-Proximal4.598685.50285K562PRPF8
chr177120294771202996+5'-UTR,CDS,intron-Proximal3.979895.23469HepG2AQR
chr177120295971202999+5'-UTR,intron-Proximal5.4293521.24327K562AQR
chr177120295571202959+5'-UTR,CDS,intron-Proximal4.4563012.08528K562AQR
chr177120295471203034+5'-UTR,CDS,intron-Proximal4.3264111.41721HepG2PRPF8
chr177120299971203020+5'-UTR,intron-Proximal4.374887.50107K562AQR
chr177120338171203441+5'-UTR,CDS,intron-Proximal3.849998.78209HepG2PRPF8
chr177120285071202956+CDS3.542867.97516HepG2GRWD1
chr177119351671193554+CDS,intron-Proximal3.892514.16174HepG2PRPF8
chr177119690071196987+CDS,intron-Proximal4.073683.31283K562PRPF8
chr177119798171198029+CDS3.665304.46864HepG2BCLAF1
chr177119920171199257+CDS4.638325.10960K562ZNF622
chr177119914371199201+CDS4.483404.90367K562ZNF622
chr177120232171202403+CDS,intron-Proximal3.253205.18023HepG2GRWD1
chr177119989871199919+CDS6.5751313.18741HepG2PRPF8
chr177119991971199964+CDS,intron-Proximal5.5810917.79328HepG2PRPF8
chr177119991871200017+CDS,intron-Proximal3.425966.00776K562PRPF8
chr177119796171198028+CDS3.059404.14618K562ZNF622
chr177119608471196155+CDS3.326243.40321HepG2GRWD1
chr177119685271196916+CDS,intron-Proximal3.645965.76104HepG2BCLAF1
chr177120232471202402+CDS,intron-Proximal3.920377.55042HepG2PPIG
chr177119676971196849+CDS4.256607.16838HepG2BCLAF1
chr177119689771196949+CDS,intron-Proximal3.148515.34140HepG2PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for COG1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for COG1 is not available on ENCORE database.

  • 55 RBPs can affect the levels of COG1.  








The Knockdown/knockout RNA-Seq assay for COG1 is not available on ENCORE database.





55 RBPs can affect the gene expression of COG1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
COG1ENSG00000166685.71011.34230867.657300.221001.909101.38680HepG2ACO1
COG1ENSG00000166685.71106.86830871.781400.344303.811802.92420HepG2AKAP8L
COG1ENSG00000166685.71823.611101330.638000.454607.844106.78320HepG2AUH
COG1ENSG00000166685.71014.75060867.525900.226002.092201.50220HepG2CKAP4
COG1ENSG00000166685.7847.78530637.836400.410402.856802.16030HepG2CPSF6
COG1ENSG00000166685.71552.924101102.172800.494503.322602.63120HepG2CELF1
COG1ENSG00000166685.71234.83880724.312200.769504.675303.41480HepG2DDX59
COG1ENSG00000166685.7822.54340685.090900.263701.955801.35410HepG2DNAJC21
COG1ENSG00000166685.7806.29460679.059900.247702.180301.58830HepG2DNAJC2
COG1ENSG00000166685.71251.58960750.551500.737607.926806.95950HepG2EIF2S1
COG1ENSG00000166685.71207.43580807.647900.580003.785202.98660HepG2EIF4B
COG1ENSG00000166685.7742.60060535.898700.470504.218702.74660HepG2FAM120A
COG1ENSG00000166685.71172.53660730.542700.682508.868407.04110HepG2FASTKD2
COG1ENSG00000166685.7996.83870616.312000.693606.465105.29130HepG2FUBP3
COG1ENSG00000166685.71246.36830892.979900.480902.798701.67700HepG2FUS
COG1ENSG00000166685.71077.11930824.333900.385802.612301.74890HepG2G3BP2
COG1ENSG00000166685.7992.72780723.019900.457303.046902.37940HepG2GPKOW
COG1ENSG00000166685.7989.77620828.399000.256702.268001.37740HepG2HDGF
COG1ENSG00000166685.71102.24500786.376300.487104.117403.27920HepG2HNRNPK
COG1ENSG00000166685.71052.92440689.992800.609605.680704.81280HepG2HNRNPLL
COG1ENSG00000166685.71022.25030764.257000.419505.253904.43950HepG2HNRNPU
COG1ENSG00000166685.71028.28390789.099900.381902.552101.90150HepG2IGF2BP2
COG1ENSG00000166685.7996.08820793.183100.328503.878202.67500HepG2KIF1C
COG1ENSG00000166685.7891.25660627.468800.506202.342001.37140HepG2METAP2
COG1ENSG00000166685.7684.47440495.819400.465103.991502.50800HepG2PKM
COG1ENSG00000166685.7696.87480477.788600.544403.532202.63080HepG2PRPF8
COG1ENSG00000166685.7736.140401121.73610-0.607706.851005.96940HepG2PUF60
COG1ENSG00000166685.71708.27520957.739900.8347017.8084016.41860HepG2QKI
COG1ENSG00000166685.71623.589301142.006800.507506.952005.67660HepG2RBM15
COG1ENSG00000166685.7826.13020984.21510-0.252601.907101.43910HepG2NELFE
COG1ENSG00000166685.7700.12530472.621600.566803.507102.63640HepG2RRP9
COG1ENSG00000166685.7943.77930680.601000.471506.468105.54520HepG2SAFB2
COG1ENSG00000166685.71528.619901054.777700.535203.341502.59840HepG2SF3A3
COG1ENSG00000166685.7533.18360682.94650-0.357102.069701.45350HepG2SF3B1
COG1ENSG00000166685.71648.99030759.901301.1176011.400709.82860HepG2SNRNP70
COG1ENSG00000166685.71020.670101442.25240-0.498808.874108.11690HepG2SRFBP1
COG1ENSG00000166685.7798.672401006.86440-0.334203.527202.75470HepG2SRSF7
COG1ENSG00000166685.71050.38300781.881800.425805.826405.07800HepG2SRSF9
COG1ENSG00000166685.7829.07980616.670600.426902.209401.59570HepG2SUPV3L1
COG1ENSG00000166685.71158.34610863.898700.423005.102604.37970HepG2TAF15
COG1ENSG00000166685.71315.39990793.722300.7287011.670209.98590HepG2TIA1
COG1ENSG00000166685.7529.02920364.265700.538303.375602.54110HepG2UCHL5
COG1ENSG00000166685.71234.37570935.426700.400005.666304.72310HepG2UPF1
COG1ENSG00000166685.71726.379401028.790000.7467023.4136022.21060HepG2ZNF622
COG1ENSG00000166685.71208.67250717.600300.752109.171208.20320K562AQR
COG1ENSG00000166685.71094.24790860.910400.345903.527602.48370K562ATP5C1
COG1ENSG00000166685.7586.30250456.863000.359802.586801.33740K562DDX6
COG1ENSG00000166685.7633.48390494.930000.356002.836501.61070K562EIF2S1
COG1ENSG00000166685.7542.17960423.943800.354802.447301.38260K562EIF4B
COG1ENSG00000166685.7775.18590574.777700.431404.073402.69710K562GLRX3
COG1ENSG00000166685.7799.52080642.043500.316402.479001.63350K562HNRNPU
COG1ENSG00000166685.7689.24140520.043000.406302.953101.71300K562IGF2BP3
COG1ENSG00000166685.7393.38170537.21740-0.449603.208802.29890K562MAGOH
COG1ENSG00000166685.71307.232201023.326900.353102.423601.36920K562MSI2
COG1ENSG00000166685.7568.63710396.980900.518303.356902.34690K562PSIP1
COG1ENSG00000166685.7619.77360813.67840-0.392702.263001.76200K562PUS1
COG1ENSG00000166685.7975.10240711.933200.453705.728804.73780K562UPF1
COG1ENSG00000166685.7775.06490609.178000.347402.476301.64610K562WDR3
COG1ENSG00000166685.71121.35270808.247700.472304.636103.47540K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for COG1 is not available on ENCORE database.





4 RBPs can affect the splicing of COG1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECOG1ENSG00000166685.7chr17+7120169171201819711998027119993271202292712024010.114000.001850.06806includedHepG2HNRNPU
SECOG1ENSG00000166685.7chr17+7120169171201819711997707119993271202292712024010.129000.000720.04774includedHepG2SRSF9
SECOG1ENSG00000166685.7chr17+712016917120181971199770711999327120229271202401-0.312000.000100.00281excludedK562HNRNPC
A3SSCOG1ENSG00000166685.7chr17+7119596571196160711960037119616071193364711935350.150000.001820.01183longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for COG1 is not avaliable on ENCORE database.