ALG2

General Information

Gene Name       : ALG2
Gene ID             : ENSG00000119523.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: ALG2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ALG2ENSG00000119523.933.6127.8230.71ENCSR000AEF
HepG2ALG2ENSG00000119523.927.9446.7037.32ENCSR985KAT
K562ALG2ENSG00000119523.917.1019.3118.20ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ALG2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ALG2 RNA is bound by 8 proteins.  







eCLIP assay for ALG2 is not avaliable on ENCORE database.





8 proteins are bound to ALG2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr9101981014101981063-3'-UTR,CDS,intron-Distal4.815057.35309K562LIN28B
chr9101980021101980086-3'-UTR,intron-Distal3.023283.15019HepG2IGF2BP1
chr9101980932101981017-3'-UTR,CDS,intron-Distal3.148933.95067HepG2SND1
chr9101979959101980022-3'-UTR,intron-Distal4.086493.76686K562IGF2BP1
chr9101984143101984199-5'-UTR,CDS,intron-Distal4.9935112.43527HepG2DDX3X
chr9101984092101984203-5'-UTR,CDS,intron-Distal5.202894.97000K562DDX3X
chr9101984068101984143-CDS,intron-Distal5.1960515.96203HepG2DDX3X
chr9101984026101984068-CDS,intron-Distal6.127468.23278HepG2DDX3X
chr9101983955101983987-CDS,intron-Distal3.067003.49427K562RBM15
chr9101983771101983847-CDS,intron-Distal4.992114.65563K562AQR
chr9101983776101983849-CDS,intron-Distal4.9258113.90941HepG2PRPF8
chr9101983911101984012-CDS,intron-Distal6.6985316.47004HepG2DDX3X
chr9101981469101981558-intron-Distal3.379974.72639K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ALG2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ALG2 is not available on ENCORE database.

  • 57 RBPs can affect the levels of ALG2.  








The Knockdown/knockout RNA-Seq assay for ALG2 is not available on ENCORE database.





57 RBPs can affect the gene expression of ALG2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ALG2ENSG00000119523.81338.02760987.640700.437903.417702.54660HepG2ASCC1
ALG2ENSG00000119523.8553.37760954.64200-0.786706.526705.01140HepG2CCAR1
ALG2ENSG00000119523.81346.34160938.312500.520804.037503.11280HepG2CIRBP
ALG2ENSG00000119523.81272.58950974.870600.384404.673503.87740HepG2CELF1
ALG2ENSG00000119523.8820.99600635.602200.369202.558801.90290HepG2DDX21
ALG2ENSG00000119523.8831.34590622.125800.418103.421902.40030HepG2DDX24
ALG2ENSG00000119523.81503.474401143.464600.394802.863102.22730HepG2DDX3X
ALG2ENSG00000119523.81086.42870802.698400.436603.479002.35390HepG2DDX5
ALG2ENSG00000119523.8797.35960623.735000.354202.421801.50400HepG2DHX30
ALG2ENSG00000119523.81332.774201043.643400.352702.111401.55000HepG2EIF4A3
ALG2ENSG00000119523.81269.59410990.635700.357802.670801.86970HepG2EIF4G2
ALG2ENSG00000119523.81408.992901171.566000.266102.568501.98570HepG2ETF1
ALG2ENSG00000119523.8502.96800698.19910-0.473203.769502.86030HepG2FUBP3
ALG2ENSG00000119523.8693.05250976.67570-0.494903.077802.37780HepG2G3BP1
ALG2ENSG00000119523.8907.25710652.884600.474603.980803.22590HepG2HNRNPA1
ALG2ENSG00000119523.81289.78340963.344600.420905.684404.42480HepG2HNRNPA2B1
ALG2ENSG00000119523.8566.97570988.57750-0.802107.709506.58890HepG2HNRNPK
ALG2ENSG00000119523.8795.69740954.84060-0.263002.545501.89740HepG2HNRNPL
ALG2ENSG00000119523.81307.84190992.829700.397502.942202.24950HepG2IGF2BP2
ALG2ENSG00000119523.81309.068401007.599800.377502.054501.34770HepG2LARP4
ALG2ENSG00000119523.8933.62400665.558200.488204.198102.70050HepG2LIN28B
ALG2ENSG00000119523.81544.140601053.036800.552105.154604.26690HepG2MAGOH
ALG2ENSG00000119523.81481.331501058.982900.484102.900302.25600HepG2MATR3
ALG2ENSG00000119523.8941.31140697.820600.431703.561902.64600HepG2MSI2
ALG2ENSG00000119523.81360.37040956.529200.508007.971407.02720HepG2PCBP1
ALG2ENSG00000119523.8864.500201052.50560-0.283902.139101.54620HepG2PUM2
ALG2ENSG00000119523.8669.258601054.18550-0.655506.121605.24390HepG2QKI
ALG2ENSG00000119523.8765.584001020.22240-0.414303.944902.94170HepG2RBM15
ALG2ENSG00000119523.8874.636401083.17450-0.308502.441201.92780HepG2NELFE
ALG2ENSG00000119523.8837.381201008.72470-0.268601.844501.32690HepG2RECQL
ALG2ENSG00000119523.8948.29460642.450700.561608.745807.69680HepG2SAFB2
ALG2ENSG00000119523.8582.44350448.739700.376102.165701.33000HepG2SERBP1
ALG2ENSG00000119523.81393.439801051.006200.406802.050601.38230HepG2SNRNP70
ALG2ENSG00000119523.81338.141701105.987400.274802.460801.97840HepG2SRFBP1
ALG2ENSG00000119523.81180.82220960.262200.298203.287302.73970HepG2SSB
ALG2ENSG00000119523.8464.66530806.89550-0.796207.272105.32890HepG2SSRP1
ALG2ENSG00000119523.8916.87840582.208100.655107.972206.43260HepG2SUPT6H
ALG2ENSG00000119523.8556.00370950.56610-0.773709.123508.20130HepG2TAF15
ALG2ENSG00000119523.8898.50920632.538100.506306.521805.56230HepG2ZC3H8
ALG2ENSG00000119523.81412.671501077.967700.390006.591305.84180HepG2ZNF622
ALG2ENSG00000119523.81810.64750822.289101.1387022.2885020.80630K562AQR
ALG2ENSG00000119523.8843.72440643.995000.389602.474101.65200K562BOP1
ALG2ENSG00000119523.81279.66650800.133300.6774013.0483011.74300K562DDX47
ALG2ENSG00000119523.81001.02620838.658900.255202.070401.32430K562DKC1
ALG2ENSG00000119523.8530.98920302.444800.811904.247902.97560K562EIF3A
ALG2ENSG00000119523.8817.49580499.991300.709207.915906.52620K562EIF4A3
ALG2ENSG00000119523.8649.00230519.972100.319702.373501.80500K562FXR1
ALG2ENSG00000119523.8735.62210527.104000.480802.682701.98900K562G3BP2
ALG2ENSG00000119523.81208.30200887.879700.444403.676202.76350K562HSPD1
ALG2ENSG00000119523.81429.008401086.848100.394803.457902.19470K562MSI2
ALG2ENSG00000119523.8587.33110419.524300.485303.094102.30050K562PRPF8
ALG2ENSG00000119523.81740.856401112.515700.645908.589107.14000K562PUF60
ALG2ENSG00000119523.81488.684401183.279600.331103.207502.05600K562PUM1
ALG2ENSG00000119523.8816.74090427.353600.934309.665208.12360K562RPS19
ALG2ENSG00000119523.8719.91980560.044700.362202.574901.88940K562SRSF1
ALG2ENSG00000119523.8642.24070859.24840-0.420002.987501.56960K562SSRP1
ALG2ENSG00000119523.8646.62660454.646300.508104.430803.38560K562SYNCRIP
ALG2ENSG00000119523.8683.11320510.906000.419002.393001.38690K562U2AF1
ALG2ENSG00000119523.8798.74330527.664200.598006.710805.46740K562U2AF2
ALG2ENSG00000119523.8848.20570681.358500.315902.744802.02900K562UPF1
ALG2ENSG00000119523.81222.13740926.341600.399703.458302.47510K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ALG2 is not available on ENCORE database.





4 RBPs can affect the splicing of ALG2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEALG2ENSG00000119523.8chr9-1019832601019834191019787071019811181019838281019842240.640000.000000.00000includedHepG2HNRNPK
SEALG2ENSG00000119523.8chr9-101983260101983419101978707101981118101983828101984224-0.097000.000030.00611excludedHepG2DDX59
SEALG2ENSG00000119523.8chr9-101983260101983419101978707101981118101983828101984224-0.128000.000410.03757excludedHepG2TBRG4
SEALG2ENSG00000119523.8chr9-1019832601019834191019787071019811181019838281019842240.221000.000180.02361includedHepG2SRSF7

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ALG2 is not avaliable on ENCORE database.