TMEM70

General Information

Gene Name       : TMEM70
Gene ID             : ENSG00000175606.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TMEM70)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TMEM70ENSG00000175606.1024.9420.8122.88ENCSR000AEF
HepG2TMEM70ENSG00000175606.1018.9726.9622.96ENCSR985KAT
K562TMEM70ENSG00000175606.1023.5027.6525.57ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TMEM70 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TMEM70 RNA is bound by 4 proteins.  







eCLIP assay for TMEM70 is not avaliable on ENCORE database.





4 proteins are bound to TMEM70 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr87489383674893957+3'-UTR,CDS4.2589922.19509K562PUM2
chr87489400274894044+3'-UTR4.135034.96821K562PUM2
chr87489379774893935+3'-UTR,CDS3.065883.94979HepG2BCLAF1
chr87488847174888517+5'-UTR,intron-Distal,intron-Proximal4.952507.55366K562DDX3X
chr87488842874888471+5'-UTR,intron-Distal,intron-Proximal4.627775.47892K562DDX3X
chr87488843574888518+5'-UTR,CDS,intron-Distal,intron-Proximal4.634715.48791HepG2DDX3X
chr87488852374888630+CDS,intron-Distal,intron-Proximal4.823978.90399HepG2DDX3X
chr87488858174888644+CDS,intron-Distal4.270964.15208K562RBM15
chr87488851974888588+CDS,intron-Distal,intron-Proximal3.984198.28216K562DDX3X
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TMEM70 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TMEM70 is not available on ENCORE database.

  • 60 RBPs can affect the levels of TMEM70.  








The Knockdown/knockout RNA-Seq assay for TMEM70 is not available on ENCORE database.





60 RBPs can affect the gene expression of TMEM70 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TMEM70ENSG00000175606.6286.18170187.858200.607202.764401.82200HepG2ABCF1
TMEM70ENSG00000175606.6520.35450376.111000.468202.286801.79860HepG2AKAP1
TMEM70ENSG00000175606.6339.27430253.222100.421902.500501.76740HepG2AKAP8L
TMEM70ENSG00000175606.6209.94800311.20800-0.567802.728701.94910HepG2ASCC1
TMEM70ENSG00000175606.6626.24860360.302500.797406.728705.79430HepG2DDX3X
TMEM70ENSG00000175606.6335.46210241.129800.476202.830702.14610HepG2DKC1
TMEM70ENSG00000175606.6192.87340297.53810-0.625402.993602.37700HepG2EIF2S1
TMEM70ENSG00000175606.6551.64630375.188700.556005.167904.08120HepG2EIF4G1
TMEM70ENSG00000175606.659.34470137.25260-1.209603.049101.98260HepG2FTO
TMEM70ENSG00000175606.6217.07900307.75100-0.503502.232301.63170HepG2G3BP1
TMEM70ENSG00000175606.6168.47860244.52420-0.537403.095302.33940HepG2HNRNPF
TMEM70ENSG00000175606.6591.59140333.704300.825906.405205.47790HepG2MATR3
TMEM70ENSG00000175606.6505.63910341.572400.565803.408102.70870HepG2NCBP2
TMEM70ENSG00000175606.674.27620131.43400-0.823402.462501.75630HepG2NSUN2
TMEM70ENSG00000175606.6413.97300205.786301.008305.815204.49450HepG2PABPC1
TMEM70ENSG00000175606.6219.76270323.00120-0.555603.371202.69100HepG2QKI
TMEM70ENSG00000175606.6423.19170200.380201.078504.261303.39550HepG2RAVER1
TMEM70ENSG00000175606.6486.83370200.769401.277808.642507.39640HepG2SF3A3
TMEM70ENSG00000175606.6240.03210345.16540-0.524103.579302.79810HepG2SLBP
TMEM70ENSG00000175606.6585.06410324.077300.8522010.390209.60390HepG2SRSF1
TMEM70ENSG00000175606.6456.51360355.425600.361002.387101.80030HepG2SRSF5
TMEM70ENSG00000175606.6592.47290402.186000.558806.044105.34090HepG2SSB
TMEM70ENSG00000175606.6298.64450196.736500.602102.911201.77850HepG2STIP1
TMEM70ENSG00000175606.6131.81630276.79630-1.070306.112105.16570HepG2SUPV3L1
TMEM70ENSG00000175606.6188.25450291.24440-0.629504.098803.43730HepG2TAF15
TMEM70ENSG00000175606.6103.98550185.41110-0.834303.039502.45510HepG2TRIM56
TMEM70ENSG00000175606.6280.32230162.368700.787704.707103.89930HepG2U2AF1
TMEM70ENSG00000175606.6297.64300195.823200.603904.298203.65570HepG2ZNF622
TMEM70ENSG00000175606.6370.26660221.736900.739604.819203.20800K562AARS
TMEM70ENSG00000175606.6578.19340378.663600.610506.294205.49140K562AGGF1
TMEM70ENSG00000175606.6835.33120394.015101.0840016.2649014.43850K562AKAP8L
TMEM70ENSG00000175606.6809.53270621.424200.381402.923401.64600K562APOBEC3C
TMEM70ENSG00000175606.61141.00140750.274900.604703.591702.94010K562AQR
TMEM70ENSG00000175606.670.38620130.13140-0.886603.357402.17210K562CCAR1
TMEM70ENSG00000175606.6860.90130452.528900.927707.755305.77750K562CCDC124
TMEM70ENSG00000175606.61118.73370865.768300.369703.654002.53020K562CELF1
TMEM70ENSG00000175606.6654.74340444.276000.559404.523702.62510K562DDX19B
TMEM70ENSG00000175606.6783.91380368.809201.0877016.8776015.38880K562DDX47
TMEM70ENSG00000175606.6499.68440342.491900.544803.034901.69000K562EEF2
TMEM70ENSG00000175606.6442.04520577.27030-0.385101.933901.31410K562EIF2S2
TMEM70ENSG00000175606.6567.82360352.426400.688006.431505.23340K562EIF3G
TMEM70ENSG00000175606.6463.50970272.327900.767206.731705.46370K562EIF4A3
TMEM70ENSG00000175606.6415.07540245.252800.759007.649205.58560K562EIF4B
TMEM70ENSG00000175606.6947.13840704.234100.427404.963803.72350K562EIF4G2
TMEM70ENSG00000175606.6139.26620215.92280-0.632703.101101.75780K562EXOSC5
TMEM70ENSG00000175606.6688.81540283.210801.2821024.0163022.34860K562FXR1
TMEM70ENSG00000175606.6526.38110286.243800.878806.573805.38070K562G3BP2
TMEM70ENSG00000175606.6676.91050418.154000.694807.548206.02030K562KIF1C
TMEM70ENSG00000175606.61125.67590750.666300.584406.422904.71530K562MSI2
TMEM70ENSG00000175606.6618.87170322.038900.942309.440408.05150K562PRPF8
TMEM70ENSG00000175606.6127.75900217.31970-0.766402.251301.44360K562PSIP1
TMEM70ENSG00000175606.61294.45850768.391000.752306.684405.41430K562PUF60
TMEM70ENSG00000175606.61326.04850817.174000.6983011.312309.08210K562PUM1
TMEM70ENSG00000175606.6486.95910273.130200.834104.456902.59940K562RAVER1
TMEM70ENSG00000175606.61114.07410328.060601.7637023.3058020.95770K562RPS19
TMEM70ENSG00000175606.6348.18220175.622900.987303.651402.17150K562SNRNP200
TMEM70ENSG00000175606.6423.34670309.951900.449702.229301.37980K562SRPK2
TMEM70ENSG00000175606.6507.12940361.526400.488203.432202.65020K562SRSF1
TMEM70ENSG00000175606.6629.58850215.346601.547607.413503.92710K562SUGP2
TMEM70ENSG00000175606.6585.00410365.950000.676702.310701.66110K562TARDBP
TMEM70ENSG00000175606.6458.04490286.627800.676202.976102.14330K562U2AF2
TMEM70ENSG00000175606.6345.05430222.415600.633503.119001.83690K562UTP3
TMEM70ENSG00000175606.6435.12790289.292100.588805.285804.15230K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TMEM70 is not available on ENCORE database.





12 RBPs can affect the splicing of TMEM70 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETMEM70ENSG00000175606.6chr8+7489131374891406748909907489109674893389748938210.172000.000110.01588includedHepG2G3BP1
SETMEM70ENSG00000175606.6chr8+748913137489140674890990748910967489338974893821-0.116000.006730.09573excludedK562SRSF1
SETMEM70ENSG00000175606.6chr8+7489131374891406748909907489109674893389748938210.235000.000000.00006includedK562AKAP8L
SETMEM70ENSG00000175606.6chr8+7489131374891406748909907489109674893389748938210.166000.000110.03779includedHepG2BCLAF1
SETMEM70ENSG00000175606.6chr8+7489131374891406748909907489109674893389748938210.383000.000000.00000includedK562PUS1
SETMEM70ENSG00000175606.6chr8+7489131374891406748909907489109674893389748938210.171000.000190.02231includedHepG2DDX6
SETMEM70ENSG00000175606.6chr8+7489131374891406748909907489109674893389748938210.147000.001040.08453includedHepG2SUPV3L1
SETMEM70ENSG00000175606.6chr8+7489131374891406748909907489109674893389748938210.253000.000000.00020includedK562RBM15
SETMEM70ENSG00000175606.6chr8+7489131374891406748909907489109674893389748938210.346000.000000.00003includedK562AGGF1
SETMEM70ENSG00000175606.6chr8+7489131374891406748909907489109674893389748938210.171000.000060.01842includedHepG2DDX55
SETMEM70ENSG00000175606.6chr8+7489131374891406748909907489109674893389748938210.148000.000010.00196includedK562ZC3H8
SETMEM70ENSG00000175606.6chr8+7489131374891406748909907489109674893389748938210.467000.000000.00000includedHepG2HNRNPC
SETMEM70ENSG00000175606.6chr8+7489131374891406748909907489109674893389748938210.565000.000000.00000includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TMEM70 is not avaliable on ENCORE database.